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All Journal Majalah Obstetri dan Ginekologi Sari Pediatri Paediatrica Indonesiana Jurnal Ilmiah Universitas Batanghari Jambi Syntax Literate: Jurnal Ilmiah Indonesia Manuju : Malahayati Nursing Journal Jurnal Respirasi (JR) Biomolecular and Health Science Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Majalah Biomorfologi (Biomorphology Journal) JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH RESEARCH Mitra Raflesia (Journal of Health Science) INDONESIAN MIDWIFERY HEALTH AND SCIENCES JOURNAL KESANS : International Journal of Health and Science Jurnal Pengabdian Masyarakat Bangsa Jurnal Widya Medika
Umiastuti, Pirlina
Department Of Public Health And Preventive Medicine, Airlangga University Medical School/Dr. Soetomo Hospital Surabaya, Indonesia.
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Journal : Majalah Biomorfologi (Biomorphology Journal)

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THE USE OF GLUCOSAMINE AND THE INCREASE OF IOP: A LITERATURE REVIEW Wega Yusan Wira Perdana; Pirlina Umiastuti; Nabila Putri Wardhani; Amirah Jasmine; Nur Milati Bani Mostavan; Nadhilah Putri Ghaisani; Audi Salman Faza
Majalah Biomorfologi Vol. 32 No. 2 (2022): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v32i2.2022.89-95

Abstract

Highlights: 1. There are differences in the result of the use of glucosamine and the increase of intraocular pressure.2. There are many other factors that may contribute to the increase in the intraocular pressure other than the use of glucosamine such as races, genetics, different dose, and duration of glucosamine use. Abstract: Background: Glucosamine is an amino monosaccharide that can directly stimulate the synthesis of glycosaminoglycans in the cartilage. It has been widely used as an osteoarthritis treatment. However, several literatures show the possible side effects of glucosamine, such as increased intraocular pressure (IOP). Objective: The objective of this study was to determine if there was any correlation between the use of glucosamine and the increase in IOP. Material and Method: This was a descriptive qualitative study that implied a systematic review design. The study sample consisted of patients with osteoarthritis (OA) and glaucoma in Iran, Indonesia, Thailand, the USA, and India between 2013 and 2018. The literature search was conducted on a database (PubMed and Google Scholar) and selected using inclusion and exclusion criteria. Discussion: The research identified 5 studies on the use of glucosamine and the increase of IOP. Two articles provide significant results on the correlation between the use of glucosamine and the increase of IOP (P < 0.05). In addition, two studies showed significant IOP reduction outcomes after discontinuation of glucosamine (P < 0.05). A case series indicated an increase in IOP during the 6th month of glucosamine use but still at normal value. Conclusion: Many other factors contribute to IOP growth, other than the use of glucosamine. Therefore, a large-scale randomized clinical trial or a multicentre cohort study using the same parameters is still needed to improve the quality of the subsequent systematic review
Co-Authors Ainiyah, Safira Nur Aldika Akbar, Muhammad Ilham Amalia, Rize Budi Ambang Kurnia Amelia Rahmah Kartika Amirah Jasmine Arya Ivan Mahendra Aryana, Hanung Asdi Wihandono Atika Atika Audi Salman Faza Ayu Pisita Wulandari Berghan Yusta Kumila Besse Ramlah Budi Prasetyo Dirda Prasasta, Reka Elvia Eighty Mardiyan K, Eighty Emyrazel Fahdizar Erwin Astha Triyono Fairuz, Jihan Jauza Fakhira, Avisha Filipus Michael Yofrido Firdausiyah Firdausiyah Hadi, Indawan Setyono Hanung Aryana Hasanah, Rizka Uswatun Imaniar Indraswara Imanina, Shabrina Nur Inar Melati , Feras Indawan Setyono Hadi Irma Irma Ivan Sofian Wibowo Jaya, Jessica Hoetama Jayanata, Muhammad Gita Jessica Hoetama Jaya Kalishah, Jihan Khansa Raihani Komaratih, Evelyn Likka, Elisantri Rambu Saja Enga Mali, Veronika Fia ManikRetno Wahyunitisari Mariska Nuriana Muhammad Fadhil Nabila Putri Wardhani Nadhilah Putri Ghaisani Neissya Nastiti Ninik Sriwijayanti Nisa', Ayu Imamatun Nita Yulia, Eli Nur Milati Bani Mostavan Palobo, Kezia Arung Prastowo, Rachmat Ageng Pratama Mahardika, Nandha Purwanto , Bambang R Yuvasanghar A/L Ravindra Rachmat Ageng Prastowo Raissa, Safira Retno Asih Setyoningrum Rizqi Handi Prayata Rozalina Loebis, Rozalina Rynda Kirana Satwikaputri S. Soedarsono Safira Nur Ainiyah Salsabila Nurulnisa Satwikaputri, Rynda Kirana Sawitri Sawitri Shabrina Nur Imanina Siti Aria Soedarsono Soedarsono Sri Umijati Subagiono, Arya Agung Hari Sudaryanti, Lestari Suropati, Bagus Meurah Swanjo, Julian Benedict Teddy Ontoseno Vemaniarti Lian Pravitasari Wega Yusan Wira Perdana Widati Fatmaningrum Wiharjo Hadisuwarno Yofrido, Filipus Michael Zahra Sabrina Setyarto