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Studi Penggunaan Sefalosporin Generasi Ketiga pada Pasien Pneumonia di Instalasi Rawat Inap Rumah Sakit Umum Haji Surabaya Worotikan, Natania Imanuella; Hasmono, Didik; Kasih, Elisabeth; Ramdani, Dewi
Jurnal Farmasi Sains dan Terapan Vol 6, No 2 (2019)
Publisher : Jurnal Farmasi Sains dan Terapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (255.059 KB) | DOI: 10.33508/jfst.v6i2.2233

Abstract

Pneumonia is an acute lung tissue infection caused by inflammation of the lung parenchyma and the presence of exudate compaction in lung tissue. Based on epidemiology, pneumonia can be differentiated into communityacquired pneumonia and health care-associated pneumonia. The HCAP category divided pneumonia into hospital acquired pneumonia and ventilator-associated pneumonia. This study aims to analyze the pattern of third generation cephalosporin use in pneumonia patients based on drug route of administration, dosage, frequency, interval and duration of drug usage, and laboratory data. This study was conducted retrospectively with time limited sampling method during the period of August 1, 2016 - August 31, 2017. The study was conducted in 31 patients with diagnosis of pneumonia undergoing hospitalization and received third generation cephalosporin antibiotic therapy at inpatient installation of RSU Haji Surabaya which traced through Medical Record. All samples were recorded on the data collection sheet, and then the data was recapitulated and analyzed. Based on the observation result, it was found that ceftriaxone with frequency and dose 2x1 g (iv) used as much as 41% (11 people), the combination between ceftriaxone 2x1 g (iv) with levofloxacin 1x1 g (iv) used as much as 22% (4 people). The longest use of third generation cephalosporin antibiotics was ceftriaxone (4-6 days) as much as 35% (12 people).
Hubungan Indeks Massa Tubuh dengan Keparahan dan Mortalitas Pasien Covid-19 Hasanah, Uswatun; Ramdani, Dewi; Darmawan, Endang; Sugiyarto, Sugiyarto
Jurnal Kesehatan Vol 13 No 2 (2022): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v13i2.3051

Abstract

Covid-19 is a novel viral disease resulting in many casualties around the world, including in Indonesia. By the 19th of January 2022, the death rate is 3.36% higher than the world’s, i.e., 1.64%. Covid-19 -related death is caused by several factors; one of them is body mass index (BMI). A patient’s BMI affects the clinical condition as well as the severity of the case. Increasing BMI is believed to be a risk and mortality factor for Covid-19 patients. This research aimed at identifying the relationship between BMI and the severity as well as mortality of Covid-19 patients. From March 2020 to June 2021, as many as 345 in-patients at RSU Haji Surabaya were studied using the retrospective cohort research method. The data were analyzed using Chi-square with <0.05 significance value to see the relationship amongst its test variables. The results indicated that there was no significant relationship between body mass index and severity and mortality in Covid-19 patients. Therefore, it can be concluded that the severity and mortality of Covid-19 patients in Indonesia were not dependent only on the increase in BMI. 
Analysis And Evaluation Of Pharmacist Power Needs With The WISN Method In The Pharmaceutical Installation Of Haji Hospital Surabaya Subhan, Muhammad; Wardani, Ratna; Ramdani, Dewi
JBMP (Jurnal Bisnis, Manajemen dan Perbankan) Vol. 7 No. 2 (2021): September
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (387.811 KB) | DOI: 10.21070/jbmp.v7i2.1476

Abstract

The success of the hospital in carrying out its functions is influenced by several factors, among which the most dominant is human resources. Human resources are one of the important factors to be able to provide quality and comprehensive services in health services and are the key determinants of the rate and quality of services. The method of calculating needs based on workload (WISN) is an indicator that shows the amount of workforce required for health facilities based on workload, so that the allocation / relocation of labor will be easier and more rational. This research is a descriptive observational research with qualitative data analysis with purposive sampling method, namely the sampling technique by determining certain criteria. The HR category that will be calculated is the pharmacist in the Pharmacy Installation of the Surabaya Haji Hospital and results in a calculation of the total need for pharmacists of 24 people, compared to the current number of pharmacists of 20 pharmacists, the addition of pharmacists is 4 people in the Home Pharmacy Installation Haji Hospital Surabaya. The current number of fulfilled personnel from the calculation results only fulfills 83% of the ideal amount generated by the WISN method. With the obstacles faced such as the large workload of clinical pharmacy services that are carried out every day. To anticipate this, it is necessary to fulfill the need for pharmacists.
The Quantitative and Qualitative Analysis of Antibiotic Use in Bone Fracture Patients in a Public Hospital in Indonesia Atmajani, Wanudya; Hasmono, Didik; Awdisma, Wien Maryati; Isparnadi, Erwien; Ramdani, Dewi
Pharmaceutical Journal of Indonesia Vol. 8 No. 1 (2022)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2022.008.01.8

Abstract

Pendahuluan: Terapi antibiotik profilaksis memiliki peran penting dalam memfasilitasi penyembuhan pasca operasi yang optimal. Penggunaan antibiotik yang tidak tepat di rumah sakit akan meningkatkan biaya terapi dan kejadian infeksi nosokomial mikroorganisme infeksius. Antibiotik profilaksis preoperasi diyakini dapat mengurangi kejadian infeksi tempat pembedahan. Tujuan: Penelitian ini bertujuan untuk mengetahui pola penggunaan antibiotik dan menganalisis penggunaan antibiotik secara kualitatif dengan metode Gyssen dan kuantitatif dengan metode defined daily dose (DDD) pada pasien rawat inap dengan fraktur tulang di Rumah Sakit Umum Haji Surabaya, Indonesia. Metode: Penelitian ini merupakan penelitian observasional deskriptif yang dilakukan terhadap 89 sampel. Data dikumpulkan secara retrospektif melalui rekam medis pada periode Januari-Desember 2019. Data penggunaan antibiotic kemudian dianalisis secara kualitatif dan kuantitatif dengan metode Gyssen dan DDD. Hasil: Pada penelitian ini, antibiotik yang banyak digunakan sebagai antibiotik profilaksis dan terapeutik pada pasien fraktur tulang adalah seftriakson. Analisis kuantitatif menggunakan metode DDD menunjukkan bahwa nilai ceftriaxone adalah 45,6/100 pasien-hari dan cefazoline adalah 3,1/100 pasien-hari. Analisis penggunaan antibiotik pada pasien fraktur tulang dengan menggunakan metode Gyssen menunjukkan bahwa penggunaan antibiotik yang rasional sebanyak 84,3%, penggunaan antibiotik tidak tepat waktu sebanyak 4,5%, dan interval pemberian antibiotik tidak tepat sebanyak 11,2%. Kesimpulan: penggunaan antibiotik pada pasien bedah fraktur sudah tergolong penggunaan antibiotik yang rasional namun penggunaan antibiotik masih melebihi standar WHO. Selanjutnya perlu dilakukan penelitian serupa dengan pengambilan data secara prospektif sehingga dapat mengamati kejadian infeksi luka operasi. Introduction: Prophylactic antibiotic therapy has an important role in facilitating optimal postoperative healing. Inappropriate use of antibiotics in hospitals will increase the cost of therapy and the incidence of nosocomial infections of infectious microorganisms. Preoperative prophylactic antibiotics are believed to reduce the incidence of surgical site infections. Objective: This study aims to determine the pattern of antibiotic use and analyse the use of antibiotics qualitatively by the Gyssen method and quantitatively by the defined daily dose (DDD) method in inpatients with bone fractures at the Haji General Hospital Surabaya, Indonesia. Methods: This study was a descriptive observational study conducted on 89 samples. Data were collected retrospectively through medical records in the period January-December 2019. Antibiotic use data were then analysed qualitatively and quantitatively using the Gyssen and DDD methods. Results: In this study, the antibiotic that was widely used as a prophylactic and therapeutic antibiotic in patients with bone fractures was ceftriaxone. Quantitative analysis using the DDD method showed that the value of ceftriaxone was 45.6/100 patient-days and cefazoline was 3.1/100 patient-days. Analysis of antibiotic use in bone fracture patients using the Gyssen method showed that the rational use of antibiotics was 84.3%, the use of antibiotics was not timely as much as 4.5%, and the interval of antibiotic administration was not appropriate as much as 11.2%. Conclusion: the use of antibiotics in fracture surgery patients is classified as rational use of antibiotics but the use of antibiotics still exceeds WHO standards. Furthermore, it is necessary to conduct a similar study with prospective data collection so that it can observe the incidence of surgical wound infection.
Pengembangan Sistem Informasi Sertifikasi Menggunakan Metode Agile Septiani, Lintang; Ramdani, Dewi; maula, Anjas Teguh; Nugroho, Nur Budi; Ar Ridho, Muhammad Fikri
Digital Transformation Technology Vol. 4 No. 2 (2024): Periode September 2024
Publisher : Information Technology and Science(ITScience)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47709/digitech.v4i2.5144

Abstract

The Academy Support Unit (UPA) at Indramayu State Polytechnic has an important role in organizing certification services to measure the skills, knowledge, and work attitudes of graduates according to industry standards. This competency certification is designed to improve the competitiveness of graduates, so that they are more easily accepted in the workforce. However, the certification process still faces several challenges, especially in administration which tends to be prone to recording errors. So that the process of reporting results is also constrained. To overcome these obstacles, Indramayu State Polytechnic developed a website-based application with the Laravel Framework called the Training and Competency Test Service Information System. This study uses an agile method approach. It is expected that the entire administrative process, from registration to reporting results, can improve efficiency and transparency. This step is also expected to support the vision of vocational education in producing competent graduates who are ready to compete in the global job market.
The Quantitative and Qualitative Analysis of Antibiotic Use in Bone Fracture Patients in a Public Hospital in Indonesia Atmajani, Wanudya; Hasmono, Didik; Awdisma, Wien Maryati; Isparnadi, Erwien; Ramdani, Dewi
Pharmaceutical Journal of Indonesia Vol. 8 No. 1 (2022)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2022.008.01.8

Abstract

Pendahuluan: Terapi antibiotik profilaksis memiliki peran penting dalam memfasilitasi penyembuhan pasca operasi yang optimal. Penggunaan antibiotik yang tidak tepat di rumah sakit akan meningkatkan biaya terapi dan kejadian infeksi nosokomial mikroorganisme infeksius. Antibiotik profilaksis preoperasi diyakini dapat mengurangi kejadian infeksi tempat pembedahan. Tujuan: Penelitian ini bertujuan untuk mengetahui pola penggunaan antibiotik dan menganalisis penggunaan antibiotik secara kualitatif dengan metode Gyssen dan kuantitatif dengan metode defined daily dose (DDD) pada pasien rawat inap dengan fraktur tulang di Rumah Sakit Umum Haji Surabaya, Indonesia. Metode: Penelitian ini merupakan penelitian observasional deskriptif yang dilakukan terhadap 89 sampel. Data dikumpulkan secara retrospektif melalui rekam medis pada periode Januari-Desember 2019. Data penggunaan antibiotic kemudian dianalisis secara kualitatif dan kuantitatif dengan metode Gyssen dan DDD. Hasil: Pada penelitian ini, antibiotik yang banyak digunakan sebagai antibiotik profilaksis dan terapeutik pada pasien fraktur tulang adalah seftriakson. Analisis kuantitatif menggunakan metode DDD menunjukkan bahwa nilai ceftriaxone adalah 45,6/100 pasien-hari dan cefazoline adalah 3,1/100 pasien-hari. Analisis penggunaan antibiotik pada pasien fraktur tulang dengan menggunakan metode Gyssen menunjukkan bahwa penggunaan antibiotik yang rasional sebanyak 84,3%, penggunaan antibiotik tidak tepat waktu sebanyak 4,5%, dan interval pemberian antibiotik tidak tepat sebanyak 11,2%. Kesimpulan: penggunaan antibiotik pada pasien bedah fraktur sudah tergolong penggunaan antibiotik yang rasional namun penggunaan antibiotik masih melebihi standar WHO. Selanjutnya perlu dilakukan penelitian serupa dengan pengambilan data secara prospektif sehingga dapat mengamati kejadian infeksi luka operasi. Introduction: Prophylactic antibiotic therapy has an important role in facilitating optimal postoperative healing. Inappropriate use of antibiotics in hospitals will increase the cost of therapy and the incidence of nosocomial infections of infectious microorganisms. Preoperative prophylactic antibiotics are believed to reduce the incidence of surgical site infections. Objective: This study aims to determine the pattern of antibiotic use and analyse the use of antibiotics qualitatively by the Gyssen method and quantitatively by the defined daily dose (DDD) method in inpatients with bone fractures at the Haji General Hospital Surabaya, Indonesia. Methods: This study was a descriptive observational study conducted on 89 samples. Data were collected retrospectively through medical records in the period January-December 2019. Antibiotic use data were then analysed qualitatively and quantitatively using the Gyssen and DDD methods. Results: In this study, the antibiotic that was widely used as a prophylactic and therapeutic antibiotic in patients with bone fractures was ceftriaxone. Quantitative analysis using the DDD method showed that the value of ceftriaxone was 45.6/100 patient-days and cefazoline was 3.1/100 patient-days. Analysis of antibiotic use in bone fracture patients using the Gyssen method showed that the rational use of antibiotics was 84.3%, the use of antibiotics was not timely as much as 4.5%, and the interval of antibiotic administration was not appropriate as much as 11.2%. Conclusion: the use of antibiotics in fracture surgery patients is classified as rational use of antibiotics but the use of antibiotics still exceeds WHO standards. Furthermore, it is necessary to conduct a similar study with prospective data collection so that it can observe the incidence of surgical wound infection.
Evaluating fondaparinux vs bovine-derived enoxaparin as halal anticoagulants in East Java Provincial Haji Hospital Samlan, Karima; Ayumuyas, Nur Palestin; Ramdani, Dewi; Zulfiana, Risa; Sari, Annisa Kartika; Isnaeni, Isnaeni
Journal of Halal Science and Research Vol. 6 No. 2 (2025): September
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/jhsr.v6i2.12277

Abstract

This study evaluated the effectiveness of two halal anti-coagulant therapies used in patients at East Java Provincial Haji Hospital. The research design was a retrospective, comparative, observational study spanning the last three years. The study population consisted of patients assigned to anti-coagulant therapy, divided into two groups based on the use of two halal anti-coagulants: bovine enoxaparin and fondaparinux. Participation in this study is voluntary, and all patient data will be kept confidential in accordance with data protection laws. Inclusion criteria were patients with diagnoses requiring anticoagulants, such as atrial fibrillation, while exclusion criteria included patients with conditions that could affect drug metabolism or response to therapy. The main variables to be assessed in this study were length of stay, which is one of the key indicators of anticoagulant effectiveness. In addition, this study also compared the cost-effectiveness of hospital care. This data will be collected through electronic medical records, followed by rigorous statistical analysis. Independent t-test and chi-square by which quantitative data, while multivariate analysis was applied to control potential confounding variables. Two anticoagulant groups were used as samples containing fondaparinux and bovine enoxaparin, respectively. Based on the observational results showed that the average length of stay for patients using the group fondaparinux was shorter than bovine enoxaparin. The bovine enoxaparin group has a lower price per dose, but based on the LOS, the fondaparinux group can reduce total hospital costs, because it has a shorter length of stay. The expectation of this research will provide insight into the effectiveness of halal anti-coagulant drugs in muslim patients, which will also assist in clinical decision making. Hopefully, the results of this research will be useful in Indonesia and other countries with large muslim populations, and can provide the scientific confirmation needed to validate the use of halal medicines. Keywords: Anticoagulant, Effectiveness, Enoxaparin, Fondaparinux, Halal pharmaceuticals.
Studi Penggunaan Sefalosporin Generasi Ketiga pada Pasien Pneumonia di Instalasi Rawat Inap Rumah Sakit Umum Haji Surabaya Worotikan, Natania Imanuella; Hasmono, Didik; Kasih, Elisabeth; Ramdani, Dewi
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol. 6 No. 2 (2019)
Publisher : Faculty of Pharmacy, Widya Mandala Surabaya Catholic University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v6i2.2233

Abstract

Pneumonia is an acute lung tissue infection caused by inflammation of the lung parenchyma and the presence of exudate compaction in lung tissue. Based on epidemiology, pneumonia can be differentiated into communityacquired pneumonia and health care-associated pneumonia. The HCAP category divided pneumonia into hospital acquired pneumonia and ventilator-associated pneumonia. This study aims to analyze the pattern of third generation cephalosporin use in pneumonia patients based on drug route of administration, dosage, frequency, interval and duration of drug usage, and laboratory data. This study was conducted retrospectively with time limited sampling method during the period of August 1, 2016 - August 31, 2017. The study was conducted in 31 patients with diagnosis of pneumonia undergoing hospitalization and received third generation cephalosporin antibiotic therapy at inpatient installation of RSU Haji Surabaya which traced through Medical Record. All samples were recorded on the data collection sheet, and then the data was recapitulated and analyzed. Based on the observation result, it was found that ceftriaxone with frequency and dose 2x1 g (iv) used as much as 41% (11 people), the combination between ceftriaxone 2x1 g (iv) with levofloxacin 1x1 g (iv) used as much as 22% (4 people). The longest use of third generation cephalosporin antibiotics was ceftriaxone (4-6 days) as much as 35% (12 people).