Article Per Year (5 Year)
p-Index From 2021 - 2026
2.461
P-Index
This Author published in this journals
All Journal Dentika Dental Journal ODONTO Dental Journal Interdental Jurnal Kedokteran Gigi (IJKG) Jurnal Ilmiah Medicamento Jurnal Abdi Dharma Masyarakat Odonto dental journal
Mochammad Taha Ma’ruf
Universitas Mahasaraswati Denpasar
Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health

Published : 22 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 22 Documents
Search

 1   2   3 
Sub-Acute Toxicity and Allergy Studies of Bidara Leaf (Ziziphus Mauritiana) Extract as A Wound Healing Material Ma'ruf, Mochammad Taha; Dewi, Putu Sulistiawati; Poernomo, Hendri
Odonto : Dental Journal Vol 10, No 2 (2023): December 2023
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.10.2.194-201

Abstract

Background: In dentistry, the wound healing process is often encountered in tooth extractions, incisions, oral and facial surgery, gingival flaps and biopsies. Post-tooth extraction wound is a medium that allows pathogenic microbes to breed and infect the wound. Wound management must be carried out as soon as possible to restore mucosal integrity so as to prevent bacterial infections penetrates the body. Bidara (Ziziphus mauritiana) is one of the plants used as traditional medicine by the community. Research on this plant as a medicinal raw material is increasing, so further research needs to be carried out to prove the safety of this medicinal plant. This study aims to determine the effects of sub-acute toxicity and allergic reactions caused after administering bidara leaf extract on the liver histopathology of mice. Methods: In vivo laboratory experimental study using a post-test only control group design with 24 mice (Mus musculus). The research sample consisted of 4 groups, namely the control group given 0.3% Na-CMC, the treatment group given bidara leaf extract at a dose of 500 mg/kg BW, 600 mg/kg BW, and 700 mg/kg BW. The treatment extract was given orally for 28 days. Results: The results of the study showed that the dose of bidara leaf extract had an effect on the liver histopathology of mice, namely at doses of 600 mg/kg BW and 700 mg/kg BW it had a toxic effect that was visible from changes in liver cell structure. Allergy tests showed that bidara leaf extract did not cause allergic reactions in mice. Conclusion: It can be concluded that bidara leaf extract (Ziziphus mauritiana) does not cause allergies and at certain doses does not have toxicity in the liver of animals study.
Advantages and Limitations of Nanomaterials in Restorative and Endodontic Treatments: A Literature Review Mochammad Taha Ma’ruf; Atia Nurul Sidiqa; Ilma Yudistian
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 22 No. 1 (2026): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v22i1.13837

Abstract

Introduction: Nanotechnology has transformed dentistry by introducing nanomaterials with superior mechanical properties, improved aesthetics, and enhanced antibacterial effects, thereby improving treatment outcomes. These materials have been widely adopted in modern dental treatments. However, concerns remain regarding their potential toxicity, production costs, and long-term effects on human health and the environment. This review explores the benefits and challenges of nanomaterials in dentistry, particularly their applications in restorative and endodontic treatments. It examines potential risks to provide a balanced perspective on their clinical use. Review: Nanomaterials enhance the strength and durability of dental restorations while reducing bacterial adhesion. In endodontics, nanomaterials enhance the antimicrobial activity and penetration of root canal sealers, thereby improving root canal disinfection and reducing the risk of reinfection. However, prolonged exposure to nanomaterials raises concerns about biocompatibility, oxidative stress, immune responses, and neurotoxicity. Current studies highlight the need for standardized safety protocols and long-term clinical trials. Conclusion: Nanotechnology offers significant advancements in dentistry, improving treatment durability and patient outcomes. However, further research is required to assess long-term safety, optimize materials for clinical use, and develop regulatory guidelines. Ensuring the biocompatibility and environmental safety of nanomaterials is a priority for their widespread adoption.
Co-Authors Alva Edy Tontowi Atia Nurul Sidiqa Bayu Prayoga Deta Putra Hendri Poernomo Ilma Yudistian Laksmi Novrina Dewi Luh Gede Pradnyani Marsetyawan Heparis Nur Ekanda Soesatyo Mbiliyora, Paskarani Metta Liliana Mochammad Yuwono Nabila, Aghnia PA Nindya Winda Wati Putra, Bayu Prayoga Deta Putu Sulistiawati Dewi Setiawan Setiawan Setiawan Setiawan Wati, PA Nindya Winda Widowati Siswomihardjo Zulni, Shalsa Septia