Sarce Makaba
Department of Master of Public Health Program, Faculty of Public Health, Cenderawasih University of Jayapura

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Determinants of Treatment Failure in Drug-Resistant Tuberculosis Patients in Papua Province Yulpriati Kalua; Hasmi; Sarce Makaba; Arius Togodly; Novita Medyati; Rosmin Mariati Tingginehe
Formosa Journal of Science and Technology Vol. 5 No. 3 (2026): March 2026
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjst.v5i3.34

Abstract

The purpose of the study was to analyze the determinants of treatment failure in RO tuberculosis patients in Papua Province. Types of analytical observational research with a cross-sectional approach. The population is 471 people, and the sampling is saturated. Data were obtained using secondary data using univariate analysis, bivariate analysis using the Chi-square test, and multivariate analysis using binary logistic regression. The results of the study were found to be 55.4% failed in the treatment of Drug-Resistant TB. Chi-square test results with a p-value of < 0.05 were occupation, OAT side effects, treatment combinations, and adherence to OAT intake. The insignificant variables were age, sex, ethnicity, comorbid DM, comorbid HIV/AIDS, and TB treatment history. Comorbid HIV AIDS is the most dominant factor for treatment failure in RO TB patients
Determinants of Incidence of Loss to Follow-up in Tuberculosis Patients at Bintuni Health Center Henderyana Arrang Pantan; Hasmi; Sarce Makaba; Arius Togodly; Novita Medyati; Rosmin Mariati Tingginehe
Formosa Journal of Science and Technology Vol. 5 No. 4 (2026): April 2026
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjst.v5i4.48

Abstract

This study aims to analyze factors related to the incidence of Loss To Follow Up (LTFU) in TB patients at the Bintuni Health Center, Teluk Bintuni Regency. The study used an analytical observational design with a cross-sectional design based on secondary data recorded in the TB 03 register. The study population is all TB patients who started treatment in the period from January 2024 to August 2025, with a total of 245 patients sampled. The results showed that the relationship between age (p=0.260), sex (p=0.998), distance traveled (p=0.967), PMO (p=0.536), and ethnicity (p=0.141) was not significant with the incidence of LTFU. Meanwhile, the variables of education (p=0.000), employment (p=0.000), and drug side effects (p=0.000) were significantly related to the incidence of LTFU. Drug side effect variables are the most dominant factor in the incidence of LTFU
Risk Factors for Compliance with Anti-Tuberculosis Drugs in Pulmonary Tuberculosis Patients at the Central Market Health Center Derlinda Natalia Londong; Hasmi; Yacob Ruru; Sarce Makaba; Arius Togodly; Muhammad Akbar Nurdin
Formosa Journal of Science and Technology Vol. 5 No. 4 (2026): April 2026
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjst.v5i4.37

Abstract

This study aims to analyze the determinants of compliance with OAT in pulmonary tuberculosis patients at the Central Market Health Center. This study used a cross-sectional design involving 158 pulmonary TB patients at the Pasar Sentral Health Center, Mimika Regency, whose samples were taken by a saturated sampling technique. Data analysis was carried out univariate, bivariate (Chi-square and Fisher Exact tests), and multivariate with logistic regression. Bivariate analysis found that age (p = 0.978), gender (p = 0.136), OAT side effects (p = 0.301), and distance to health facilities (p = 0.635) were not significant with adherence to OAT taking. Comorbidity variables were significantly related (p = 0.016; RP = 2,808; 95% CI: 1,445–5,457). Multivariate analysis confirmed comorbidity as a significant factor (p = 0.008; Exp(B) = 5.487), while gender showed a significant tendency (p = 0.058; Exp(B) = 2.428)
Risk Analysis of Drug-Resistant Tuberculosis Incidence in Papua Province Hasriyati; Hasmi; Arius Togodly; Sarce Makaba; Agus Zainuri; Muhammad Akbar Nurdin
Formosa Journal of Science and Technology Vol. 5 No. 4 (2026): April 2026
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjst.v5i4.35

Abstract

Drug-resistant tuberculosis is a public health threat because it contributes to the increasing incidence of tuberculosis. The purpose of this study is to determine the risk of the incidence of Drug-Resistant Tuberculosis (TB C RO) in Papua Province. Types of analytical observational research with a cross-sectional approach. The population is 272 people, and the sample is the total population. The secondary data were then analyzed univariately, bivariately with the Chi-Square test, and multivariately using binary logistics. The results of the study found that factors that were significantly related to the incidence of RO tuberculosis were ethnicity, HIV comorbidities, treatment history, contact examinations and HIV comorbidities were the dominant factors. Insignificant variables are Age, Gender, and occupation