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Identifikasi Senyawa BTEX pada Asap Kendaraan Bermotor Roda Dua MAULANA, YUSUF EKA; YULIANA, TRISNA; ROHMAH, AINI ASPIATI
Jurnal Reka Lingkungan Vol 9, No 2 (2021)
Publisher : Institut Teknologi Nasional, Bandung

Â AbstrakPenggunaan kendaraan bermotor roda dua di Indonesia semakin berkembang pesat. Semakin tinggi tingkat penggunaan transportasi yang beroperasi disuatu daerah, maka akan semakin tinggi pula potensi pencemaran udara di daerah tersebut. Jika pembakaran pada kendaraan bermotor tidak sempurna maka dapat dihasilkan senyawa yang berbahaya yaitu benzene (C6H6), toluene (C7H8), ethylbenzene (C8H9), dan xylene (C8H10) atau biasa disingkat BTEX. Tujuan penelitian ini adalah untuk mengidentifikasi senyawa BTEX dan senyawa hidrokarbon lainnya dalam asap kendaraan bermotor dengan menggunakan kromatografi gas-spektrometer massa (GC-MS). Hasil identifikasi menunjukkan adanya hubungan yangsangat kuat antara standard dengan hasil pengukuran yaitu dengan R2 di atas 0,99. Identifikasi menunjukkan senyawa BTEX yang terbentuk adalah Benzene, Toluene, Etil Benzene, Xylene.Kata kunci: kendaraan bermotor, hidro karbon, BTEX, GC-MS.AbstractThe use of two wheels motorized vehicles or motorcycles in Indonesia is growing rapidly. It has been known that the greater the number of two wheels motorized vehicles the higher the potential for air pollution. If the combustion occur incomplete, hazardous compounds can be generated, namely benzene (C6H6), toluene (C7H8), ethylbenzene (C8H9), and xylene (C8H10) or commonly abbreviated BTEX. The purpose of this study was to identify BTEX compounds and other hydrocarbon compounds in motor vehicle fumes using gas chromatography-mass spectrometers. The identification results indicate a very strong relationship between the standard and the measurement results, with R2 above 0.99. Identification shows that BTEX compounds formed are Benzene, Toluene, Ethyl Benzene, Xylene.Â Keywords: motorcycles, hidro karbon, BTEX, GC-MS.

Identifikasi Senyawa BTEX pada Asap Kendaraan Bermotor Roda Dua MAULANA, YUSUF EKA; YULIANA, TRISNA; ROHMAH, AINI ASPIATI
Jurnal Reka Lingkungan Vol 9, No 2 (2021)
Publisher : Institut Teknologi Nasional, Bandung

Â AbstrakPenggunaan kendaraan bermotor roda dua di Indonesia semakin berkembang pesat. Semakin tinggi tingkat penggunaan transportasi yang beroperasi disuatu daerah, maka akan semakin tinggi pula potensi pencemaran udara di daerah tersebut. Jika pembakaran pada kendaraan bermotor tidak sempurna maka dapat dihasilkan senyawa yang berbahaya yaitu benzene (C6H6), toluene (C7H8), ethylbenzene (C8H9), dan xylene (C8H10) atau biasa disingkat BTEX. Tujuan penelitian ini adalah untuk mengidentifikasi senyawa BTEX dan senyawa hidrokarbon lainnya dalam asap kendaraan bermotor dengan menggunakan kromatografi gas-spektrometer massa (GC-MS). Hasil identifikasi menunjukkan adanya hubungan yangsangat kuat antara standard dengan hasil pengukuran yaitu dengan R2 di atas 0,99. Identifikasi menunjukkan senyawa BTEX yang terbentuk adalah Benzene, Toluene, Etil Benzene, Xylene.Kata kunci: kendaraan bermotor, hidro karbon, BTEX, GC-MS.AbstractThe use of two wheels motorized vehicles or motorcycles in Indonesia is growing rapidly. It has been known that the greater the number of two wheels motorized vehicles the higher the potential for air pollution. If the combustion occur incomplete, hazardous compounds can be generated, namely benzene (C6H6), toluene (C7H8), ethylbenzene (C8H9), and xylene (C8H10) or commonly abbreviated BTEX. The purpose of this study was to identify BTEX compounds and other hydrocarbon compounds in motor vehicle fumes using gas chromatography-mass spectrometers. The identification results indicate a very strong relationship between the standard and the measurement results, with R2 above 0.99. Identification shows that BTEX compounds formed are Benzene, Toluene, Ethyl Benzene, Xylene.Â Keywords: motorcycles, hidro karbon, BTEX, GC-MS.

Growth and yield response of Tanjung II and Unpad CB2 red chili varieties grown in the medium land Lestari, Rahma Wati; Kusumiyati, Kusumiyati; Mubarok, Syariful; Maulana, Yusuf Eka
Kultivasi Vol 23, No 1 (2024): Jurnal Kultivasi
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/kultivasi.v23i1.42551

Red chili is an important commodity that is daily needed by the community. Non-central chili areas often experience deficits due to the high consumption volume and low productivity of chili peppers. To increase the productivity of chili in non-central areas, expand it in the medium land. This study aims to determine the productivity of two introduced chili varieties in the medium land whose adaptation areas came from lowland and highland areas. This study was analyzed using an independent sample T-test at a significant level of 5%. The results of the data analysis showed that the Tanjung II variety significantly influenced the parameters of stem diameter and weight of the fruit. Meanwhile, the Unpad CB2 variety significantly influences the parameters of plant height, number of leaves, number of flowers, number of fruits, and fruit set. However, both varieties have no noticeable effect on the weight parameters of the cropping fruit and potential yield in hectares. The Tanjung II variety experienced a decrease in yield by 54.58%, while the Unpad CB2 variety was 53.56%.

Synthesis, Evaluation, and Molecular Docking Study of 4-Monoacyl Resorcinol Against Tyrosinase Enzyme Danova, Ade; Maulana, Yusuf Eka; Hermawati, Elvira; Chavasiri, Warinthorn
Indonesian Journal of Chemical Research Vol 11 No 2 (2023): Edition for September 2023
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598//ijcr.2023.11-nov

Tyrosinase is a crucial enzyme in melanin production to protect the skin from ultraviolet, leading to skin cancers. This study synthesized eight compounds of acyl resorcinol with long-chain carbon (1-8) and structurally elucidated by 1H and 13C NMR. The in vitro evaluation of eight synthesized compounds against tyrosinase enzyme showed that 4-heptanoyl resorcinol (6) exhibited high inhibitory activity compared with the kojic acid as standard. In addition, the molecular docking study demonstrated that 6 showed lower binding energy (-7.3 kcal/mol) than kojic acid (-6.9 kcal/mol) and possessed interaction with crucial residues in the active site.

The LC-MS of Grammatophyllum scriptum (Lindl.)Bl. and Cytoxic Activity Test: LC-MS of Grammatophyllum scriptum (Lindl.)Bl. and Cytoxic Activity Test de Fretes, Christina; Simaremare, Eva; Gunawan, Elsye; Agustini, Verena; Maulana, Yusuf Eka; Fadhilah, Nabila Nur
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 13 No 2 (2021): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Tiger orchid (Grammatophyllum scriptum (Lindl.) Bl.) It is one of the plants that are favored among the community as ornamental plants because of its beautiful flowers. Tiger orchids have secondary metabolite compounds of alkaloids, flavonoids, and tannins that can be used as traditional medicine. However, research on tiger orchids in the field of pharmacology is still very limited. The purpose of this study is to find out the content of chemical compounds contained in the herb extract of tiger orchids (Grammatophyllum scriptum (Lindl.) Bl.) as well as LC₅₀ and concentration of tiger orchid herb extract (Grammatophyllum scriptum (Lindl.) Bl.) It most effectively kills shrimp larvae (Artemia salina Leach.). The sample used was sampled using 96% ethanol. Tiger orchid (Grammatophyllum scriptum (Lindl.) Bl.) pregnant 2′,6′-Dihydroxy-4′-methoxy-dihydrochalcone, apigenin-7-O-α-L-rhamnose(1→4)-6"-O-acetyl-β-D-glucoside, kushenol H, rubrofusarin, 3-hydroxy baicalein and luteolin obtained from the results of the analysis using Liquid Chromatography Mass Spectrometry (LCMS). The results showed that the herb extract of tiger orchid (Grammatophyllum scriptum (Lindl.) Bl.) has cytotoxic activity with an LC₅₀ value of 150.96 ppm.

Effect of Poultry Manure and Ethephon on Growth, Yield, and Quality of Cayenne Pepper (Capsicum frutescens L.) ‘Ratuni UNPAD’ Kusumiyati, Kusumiyati; Ramadhani, Rahmatillah; Maulana, Yusuf Eka; Hamdani, Jajang Sauman
AGRIVITA Journal of Agricultural Science Vol 46, No 1 (2024)
Publisher : Faculty of Agriculture University of Brawijaya in collaboration with PERAGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17503/agrivita.v46i1.4034

The production of 'Ratuni UNPAD' cayenne pepper can be increased using organic chicken manure. However, the application of ethephon is needed during fertilization due to the significantly slow flower initiation. Therefore, this study aims to determine the interaction between chicken manure and ethephon on the growth, yield, and quality of the 'Ratuni UNPAD' cayenne pepper. Planting is carried out 829 meters above sea level (masl), and a factorial randomized block experimental design comprises 2 factors with 3 replications. The first factor is the dose of chicken manure (10, 20, 30, and 40 t/ha), while the second is the ethephon concentration (0, 500, 1000, and 1500 ppm). The results showed no interaction between poultry manure and ethephon on the growth, yield, and quality of the 'Ratuni UNPAD' cayenne pepper. According to the doses of chicken manure, 40 t/ha significantly affects the flower initiation, fruit number, weight, length, and diameter, as well as capsaicin and dihydrocapsaicin. The 30 t/ha shows the highest value for the number of leaves and productive branches, while 20 tons dose/ha influences flavonoids, phenolics, and total carotenoids. The ethephon concentration of 1500 ppm significantly affects the flower initiation, fruit length, diameter, capsaicin, and dihydrocapsaicin.

Potential of Favipiravir Analogs as SARS-CoV-2 RdRp Inhibitors: Synthesis and In Silico Studies Alni, Anita; Lokitha, Angela; Maulana, Yusuf Eka; Hermawati, Elvira; Danova, Ade
Indonesian Journal of Chemistry Vol 26, No 1 (2026)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.98538

The novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for causing the lethal infectious disease known as COVID-19. The RNA-dependent RNA polymerase (RdRp) is a pivotal component that facilitates the translation of viral RNA into viral proteins. Therefore, our study aimed to synthesize new inhibitors from favipiravir (FVP) analogs by modifying the hydrophobicity through a nucleophilic aromatic substitution at the C-6 position of the pyrazine ring with alkoxy groups under acidic conditions. Moreover, the synthesized FVP analogs were investigated for their antiviral potency against SARS-CoV-2 RdRp through in silico studies. Five FVP analogs (3–7), including four known (3, 4, 5, 7) and one new (6), were successfully synthesized with yields ranging from 2.3 to 32.7%. All favipiravir analogs could be drug-likeness with inactive hepatotoxicity and carcinogenicity. The docking study showed that compound 5 exhibited a strong binding affinity with a binding score of −7.00 kcal/mol by interacting with the catalytic site residues of Asp618 and Asp760 of SARS-CoV-2 RdRp. Furthermore, the molecular dynamics simulation revealed that the compound 5 was stable, as indicated by RMSD, Rg, solute H-bonds, RMSF, and binding energy calculations. Thus, these results suggest that the FVP-RTP analog (5) may have antiviral potency by targeting SARS-CoV-2 RdRp.

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