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All Journal Chemica: Jurnal Ilmiah Kimia dan Pendidikan Kimia PROSIDING SEMINAR KIMIA Jurnal Ilmiah Manuntung Jurnal Riset Kefarmasian Indonesia Bioscientist : Jurnal Ilmiah Biologi FASKES : Jurnal Farmasi, Kesehatan, dan Sains Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan JI-KES (Jurnal Ilmu Kesehatan)
Warnida, Husnul
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences

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PENGARUH DUKUNGAN KELUARGA TERHADAP KEPATUHAN MINUM OBAT PASIEN HIPERTENSI DI PUSKESMAS MUARA WIS Handayani, Sri Endah; Warnida, Husnul; Sentat, Triswanto
Jurnal Ilmiah Manuntung Vol 8 No 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.527

Abstract

One of the public health concerns is drug non-adherence. The main cause of poor hypertension control is noncompliance with antihypertensive medications. The elements that drive compliance behavior are numerous and complicated, with social support being one of them. Family support is critical in health care since it is through family support that a healthy family can be achieved. Family members can help by providing information about their sickness or reminding them to take their medications. The goal of this research was to identify the relationship between family support and medication adherence in hypertensive patients at Muara Wis Health Center, Kutai Kartanegara Regency, Province East Borneo. This study is descriptive correlational and uses a cross-sectional method, which involves measuring or observing at the same time and the same location. The participants in this study were 100 hypertensive patients of Muara Wis Health Center. The data in this study were analyzed using Spearman rank correlation. Based on the MMAS (Morisky Medication Adherence Scale) questionnaire, medication adherence in hypertensive patients at the Muara Wis Health Center had 52 percent low adherence, 29 percent moderate adherence, and 19 percent high adherence. According to pill count, low adherence patients was 51 percent, moderate adherence was 29 percent, and high adherence was 20 percent. Patients with hypertension who had poor family support were 54 percent, those who received moderate family support were 26 percent, and those who received strong family support were 20 percent. Hence, there is a significant relationship between family support and medication adherence in hypertensive patients of Muara Wis Health Center.
KINERJA DAN MUTU PELAYANAN KEFARMASIAN DI PUSKESMAS BAQA DI KOTA SAMARINDA Warnida, Husnul; Pertiwi, Sari Putri; Syamsul, Eka Siswanto
Jurnal Ilmiah Manuntung Vol 7 No 2 (2021): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v7i2.447

Abstract

Community Health Center (puskesmas) is the basic service health facility in Indonesia. Community Health Center organizes individual health efforts and community health efforts that must be supported by a quality pharmaceutical care. Pharmaceutical care at health center must comply with Pharmaceutical Care Standards. This study aims to determine the performance and quality of pharmaceutical care at Baqa Health Center according to Permenkes no 74/2016 and Permenpan 14/2017. This research is a descriptive research. Respondents were 306 patients who received pharmaceutical care at Baqa Health Center. The data collected were patient satisfaction level, measurement of the average time for drug compounding, the average time for drug delivery and drug information administration, and the percentage of compliance with the service standards. The results showed that the quality of pharmaceutical care at Baqa Community Health Center was 93.33% in the good category, and the performance value of pharmaceutical care at the Baqa Community Health Center was 81.09 in the good category.
Aktivitas dan Stabilitas Fisik Lotion Tabir Surya dari Ekstrak Daun Rambai Warnida, Husnul; Nurhasnawati, Henny; Sukawaty, Yullia; Ardhita, Ardhita
FASKES : Jurnal Farmasi, Kesehatan, dan Sains Vol. 3 No. 1 (2025): Bulan Juli 2025, FASKES : Jurnal Farmasi, Kesehatan, dan Sains
Publisher : Program Studi Farmasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32665/faskes.v3i1.3007

Abstract

Background: Long-term, intense sun exposure can cause erythema and sunburn, as well as premature aging and skin cancer. For generations, the people of the Banjar tribe of Borneo have applied a wet paste of Sonneratia caseolaris leaves mixture on the skin when undertaking tasks in the hot sun. The Sonneratia caseolaris tree is a mangrove plant that grows on river banks throughout the Borneo Island. Objectives: The study aims to formulate Sonneratia caseolaris leaves ethanol extract into a stable lotion and test its efficacy as a sunscreen. Methods: Sonneratia caseolaris leaves were macerate with 70% ethanol, and the sunscreen activity of the extract was examined in vitro with a UV-visible spectrophotometer, and then formulated into a lotion dosage form. Organoleptic and homogeneity observations, pH measurements, viscosity measurements, and spreadability measurements were all performed on the lotion. Following that, the lotion sunscreen activity of was tested in vitro. Results: The Sonneratia caseolaris extract sunscreen lotion has met the requirements of organoleptic, homogeneity, pH, viscosity, and spreadability tests. Conclusions and suggestions: Sunscreen lotion with 2.5% Sonnerata caseolaris extract classified as standard suntan. Sonneratia caseolaris extract of Borneo has the potential to develop as a raw material for herbal cosmetics.
Uji Aktivitas Antibakteri Ekstrak Metanol Propolis dari Lebah Kelulut (Heterotrigona itama) terhadap Bakteri Pseudomonas aeruginosa dan Staphylococcus aureus Wulandari, Dyah Tantri; Supomo, Supomo; Warnida, Husnul
Bioscientist : Jurnal Ilmiah Biologi Vol. 11 No. 2 (2023): December
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v11i2.9373

Abstract

One of the causes of infection is influenced by the occurrence of wounds. Treatment of infected wounds using antibiotics. But antibiotics causes resistance. Then another alternative material from natural ingredients is used, is Propolis from Heterotrigona itama bees. This study aims to determine the inhibition, MIC and MBC of Propolis methanol extract with concentrations of 10%,20%30%,40%,50% against Pseudomonas aeruginosa and Staphylococcus aureus. Research uses experimental research with a non-probability sampling technique, purposive sampling. The extraction method uses methanol solvent maceration. Antibacterial test was carried out by disc diffusion method, positive control of 0.1% clindamycin, negative control of DMSO. The independent variable is the concentration of propolis methanol extract and the dependent variable is the inhibition zone formed and the MIC and MBC values. Analyzed statistically using the ANOVA. Propolis methanol extract inhibited Pseudomonas aeruginosa bacteria at concentrations of 10%:7.74mm, 20%:8.05mm, 30%:10.00mm, 40%:10.05mm, 50%:12,25mm, and can inhibit the growth of Staphylococcus aureus bacteria at concentrations of 10%:7,05mm, 20%:8.00mm, 30%:10.20mm, 40%:11.15mm, 50%:12,05mm. MIC and MBC methanol extract of propolis on the bacteria Pseudomonas aeruginosa and Staphylococcus aureus of 100 mg/ml. Statistical test results showed that all concentrations of propolis methanol extract had a significant difference with the positive control of Clindamycin 0.1%.
Aktivitas Anti Jamur Fraksi Aktif Ekstrak Etanol Umbi Bawang Rambut (Allium Chinense G.Don) terhadap Jamur Candida Albicans Supomo, Supomo; Idriana, Idriana; Eka, Audinah; Indra, Indra; Huda, Miftahul; Warnida, Husnul
JI-KES (Jurnal Ilmu Kesehatan) Vol. 4 No. 2 (2021): JI-KES (Jurnal Ilmu Kesehatan)
Publisher : LPPM Universitas Hafshawaty Zainul Hasan Probolinggo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33006/ji-kes.v4i2.188

Abstract

AbstrakTumbuhan umbi bawang rambut (Allium chinense G.Don) memiliki efek sebagai antijamur karena mengandung metabolit sekunder seperti flavanoid, alkaloid dan saponin. Tujuan penelitian ini adalah mengetahui aktivitas antijamur ekstrak umbi bawang rambut melalui proses fraksinasi menggunakan pelarut N-heksan, etil asetat, kloroform dan etanol-air. Penelitian yang dilakukan adalah penelitian eksperimental. Sampel yang digunakan adalah umbi bawang rambut yang diperoleh di kampung Kelasan kecamatann Sungai Payang Kutai Kartanegara. Penelitian ini menggunakan metode maserasi dengan pelarut etanol 70%, metode uji aktivitas antijamur berdasarkan metode difusi cakram terhadap jamur Candida albicans dengan konsentrasi 5%, 10%, 25%, dan 50%, dengan kontrol negatif DMSO 50%. Hasil penelitian menunjukkan bahwa semua fraksi dari ekstrak etanol umbi bawang rambut memiliki aktivitas antijamur. Aktivitas antijamur fraksi etil asetat memberikan daya hambat yang paling besar terhadap Candida albicans diantara fraksi lainnya. Kata kunci:  candida albicans; Allium chinense G. Don; antijamur; fraksi AbstractAllium chinense has an antifungal effect because it contains secondary metabolites such as flavonoids, alkaloids and saponins. The purpose of this research is to investigate the antifungal activity of Allium chinense extract through fractionation process using N-hexane solvent, ethyl acetate, chloroform and ethanol-water. The research is experimental research. Samples used are the Allium chinense found in  Kelasan Sungai Payang  Kutai Kartanegara. Using maseration method with 70% ethanol solvent, antifungal activity test method based on disc diffusion method on Candida albicans fungi with concentration of 5%, 10%, 25%, and 50%, with negative control of DMSO 50%. The results showed that all fractions of Allium chinense ethanol extract had antifungal activity. The antifungal activity of the ethyl acetate fraction provides the greatest resistance to Candida albicans among other fractions. Keywords:  candida albicans, allium chinense G. Don, antifungal, fraction
Uji Aktivitas Antioksidan Ekstrak Baccaurea Lanceolata Fructus dengan Metode ABTS dan DPPH Rahman, Rauli Dimas Nur; Supomo, Supomo; Warnida, Husnul
JI-KES (Jurnal Ilmu Kesehatan) Vol. 6 No. 2 (2023): JI-KES (Jurnal Ilmu Kesehatan)
Publisher : LPPM Universitas Hafshawaty Zainul Hasan Probolinggo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33006/jikes.v6i2.546

Abstract

Abstrak Radikal bebas dapat menyebabkan kerusakan pada tubuh yang berlanjut kepada penyakit kronis seperti kanker, penyakit neurodegeneratif dan diabetes. Antioksidan merupakan suatu zat yang memiliki kemampuan untuk memperlambat proses oksidasi yang disebabkan radikal bebas. Ekstrak buah limpasu (Baccaurea lanceolata) memiliki kandungan senyawa flavonoid dan tannin. Metabolit sekunder seperti flavonoid dan tanin ini memiliki aktivitas antioksidan.  Tujuan penelitian ini adalah untuk mengetahui aktivitas antioksidan ekstrak buah limpasu menggunakan metode ABTS (2,2-azinobis-3-Ethylbenzothiazoline-6-Sulfonic Acid) dan DPPH (1,1-difenil-2-pikrilhidrazil) melalui nilai IC50. Penelitian yang dilakukan bersifat eksperimental. Objek penelitian ini adalah aktivitas antioksidan dari metode ABTS dan DPPH. Konsentrasi ekstrak etanol buah limpasu diukur menggunakan spektrofotometri UV-Vis untuk mendapatkan persen inhibisi dari sampel. Persen inhibisi dimasukkan ke dalam persamaan regresi linear untuk mendapatkan nilai IC50 dari kedua metode uji. Berdasarkan hasil penelitian diperoleh nilai IC50 sebesar 721,19 ppm pada metode DPPH yang termasuk kategori antioksidan tidak aktif, sedangkan pada uji ABTS didapatkan nilai IC50 sebesar 118,70 ppm yang termasuk kategori antioksidan sedang. Keywords: antioksidan, buah limpasu, ABTS, DPPH, IC50    Abstract Free radicals can harm the body and cause chronic diseases such as cancer, neurodegenerative diseases, and diabetes. Antioxidants are substances that have the ability to slow the oxidation process caused by free radicals. Limpasu fruit extract (Baccaurea lanceolata) contains flavonoid and tannin. Flavonoids and tannins have antioxidant activity. The goal of this study was to determine the antioxidant activity of limpasu fruit extract using the ABTS (2,2-azinobis-3-ethylbenzothiazoline-6-sulfonic acid) and DPPH (1,1-diphenyl-2-picrylhydrazil) methods using the IC50 value. This study is an experiment. The antioxidant activity of the ABTS and DPPH methods is the focus of this study. Independent variables of this study were limpasu fruit extract with concentration of 100; 200; 300; 400 500 ppm in DPPH and 30; 40; 50; 60; 70 ppm in ABTS, dependent variable is the antioxidant activity of limpasu fruit extract. The concentration of limpasu fruit extract measured using UV-Vis spectrophotometry to obtain the inhibition percentage of sample. The inhibition percentage was then entered into a linear regression equation to calculate the IC50 value for both methods. According to the study's findings, the IC50 value in the DPPH method was 721.19 ppm, indicating that it was an inactive antioxidant, whereas the IC50 value in the ABTS test was 118.70 ppm, indicating that it was a moderate antioxidant. Keywords: antioxidants, limpasu fruit, ABTS, DPPH, IC50
Co-Authors Anita Apriliana, Anita Ardhita, Ardhita Ardhita, Fazri Wisnu Ardita, Ardita Eka Siswanto Syamsul Eka, Audinah Handayani, Sri Endah Henny Nurhasnawati Idriana, Idriana Ilham Ilham Indra Indra Masliyana, Agustiani Mega, Mega Miftahul Huda Mursyidin, Musyidin Pertiwi, Sari Putri Rahman, Rauli Dimas Nur Risa Supriningrum Said, Bagus Moch sapri sapri Sukawaty, Yullia Supomo Supomo Triswanto Sentat Wulandari, Dyah Tantri