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Penyuluhan dan Workshop Obat Nyamuk Sintetis dan Alami Sebagai Tindakan Pencegahan DBD Agnes Anania Triavika Sahamastuti; Elsabda Siratan; Theodore Ebenezer Leonard; Gisella Edny Tjugianto; Leonny Yulita Hartiadi; Istiqomah Agusta
JPPM (Jurnal Pengabdian dan Pemberdayaan Masyarakat) VOL. 3 NOMOR 2 SEPTEMBER 2019 JPPM (Jurnal Pengabdian dan Pemberdayaan Masyarakat)
Publisher : Lembaga Publikasi Ilmiah dan Penerbitan (LPIP)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (624.545 KB) | DOI: 10.30595/jppm.v3i2.4560

Abstract

Selama bulan Januari-Februari 2016, Jakarta Timur menduduki peringkat kedua dalam jumlah penderita DBD. Hal ini diperkirakan karena kurangnya partisipasi masyarakat dalam pemberantasan sarang nyamuk dan menjaga sanitasi. Hingga saat ini, masyarakat umum menggunakan obat pengusir nyamuk untuk menghindari gigitan nyamuk. Namun penggunaan pengusir nyamuk sintetis dengan cara yang salah dan dalam jangka waktu lama dapat berdampak buruk terhadap kesehatan. Kegiatan Pengabdian Masyarakat ini bertujuan untuk meningkatkan pengetahuan masyarakat mengenai bahaya penggunaan obat pengusir nyamuk sintetis dan pemberian solusi melalui bahan alamiah berkhasiat mengusir nyamuk. Kegiatan ini dilakukan di wilayah RW 11, Pulomas Barat, DKI Jakarta dengan melibatkan kelompok ibu PKK dan Jumantik (Jumat Bebas Jentik) dan dihadiri oleh 37 orang partisipan. Hasil evaluasi menunjukkan bahwa pengetahuan para partisipan mengenai bahaya obat nyamuk sintetis beserta cara pembuatan obat nyamuk alami meningkat setelah penyuluhan. Data mengenai tingkat penggunaan obat pengusir nyamuk di daerah warga juga berhasil diperoleh. Para partisipan dilatih membuat lotion pengusir nyamuk dari bahan alami diakhir kegiatan. Kegiatan ini diharapkan dapat meningkatkan kesadaran masyarakat untuk berpartisipasi aktif dalam menurunkan angka kejadian penyakit DBD dengan memanfaatkan bahan-bahan alami yang terjangkau dan mudah diperoleh.
Comparison of Antimicrobial Activity between Ethanolic Extract and Essential Oil of Ginger (Zingiber officinale) against Food-borne Bacteria Foustine, Shania; Andre, Andre; Setiadi, Bastian; Hartiadi, Leonny Yulita; Sahamastuti, Agnes Anania Triavika
Indonesian Journal of Life Sciences 2019: IJLS Vol 01 No .02
Publisher : Indonesia International Institute for Life Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (474.707 KB) | DOI: 10.54250/ijls.v1i2.21

Abstract

Background: Ginger (Zingiber officinale) is one of the most well-known spices with antimicrobial activity. However, different extraction methods of ginger will result in different antimicrobial properties due to the various substances extracted. This study aimed to compare antimicrobial activity between ethanolic extract and essential oil of ginger against food-borne bacteria grown in 2.1% Mueller Hinton agar. Methods: Fresh ginger rhizomes were extracted either by using vapor distillation method or maceration using ethanol to obtain ginger essential oils (GEO) and ginger ethanolic extract (GEE), respectively. Ethanolic extract and essential oil of ginger at different concentrations were then tested for their antimicrobial activity using disk diffusion method against Escherichia coli, Bacillus subtilis, Salmonella typhi, and Staphylococcus aureus. Tetracycline was also used as a standard of antibacterial agent. Results: Ginger essential oil in 25%, 50%, and 100% showed significant growth inhibition of four types of bacteria compared to ginger ethanolic extract. This antimicrobial effect of ginger essential oil was shown to be dose-dependent. However, it has been demonstrated that ginger ethanolic extract 50% and 100% has a stronger antimicrobial effect against B.subtilis. Conclusion: Ginger essential oil and ethanolic extract showed different degree of antibacterial activity against food-borne bacteria due to compound contained within respective extracts, with a higher degree of activity found in ginger essential oil. These may show that different ginger extract may have different antibacterial activity.
Synergistic Antibacterial Activities of Ginger and Lemongrass Essential Oils as an Alternative Prevention to Food-Borne Disease Sahamastuti, Agnes Anania Triavika; Andre, Andre; Foustine, Shania; Sumarpo, Anton; Hartiadi, Leonny Yulita
Indonesian Journal of Life Sciences 2019: IJLS Vol 01 No .02
Publisher : Indonesia International Institute for Life Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (433.341 KB) | DOI: 10.54250/ijls.v1i2.25

Abstract

Background: Lemongrass and ginger are traditional food ingredients in Asian countries, including Indonesia, Thailand, India, and Malaysia. Although their single essential oil has been assessed for its antibacterial activities, no report has been done for their combination. Material and methods: Our study evaluated single and combination of these herbs for their antibacterial properties against food-borne bacteria E. coli (NEB® catalog No. C2989K), B. subtilis (ATCC 6633), S. typhi (ATCC 14028) and S. aureus (InaCC B4). Essential oil of lemongrass and ginger were obtained by steam distillation and their antimicrobial were evaluated using disk diffusion assay with chloramphenicol as the standard antibiotic. Synergistic activity was assessed using the combination of materials at two or four-fold dilution from their respected MIC value. Results: We confirmed that single lemongrass and ginger essential oils inhibited the bacteria growth with MIC value of about 1-5% and 2.5-5%, respectively. Moreover, their synergism activities were observed when both were mixed at two-fold dilution from their respective MIC. Conclusion: We conclude that the combination of the ginger essential oils and lemongrass essential oils may have potential as a natural preservative to prevent food-borne diseases.
A Review of Phytochemical Properties and Therapeutic Activities of Glebionis coronaria Wijaya, Evelyn Jeanette; Nathanael, Joshua; Carolan, Orlando; Adiyanto, Shakila Angjaya; Bun, Wiranata Buntaran; Sahamastuti, Agnes Anania Triavika
Indonesian Journal of Life Sciences 2020: IJLS Vol 02 No .02
Publisher : Indonesia International Institute for Life Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (446.061 KB) | DOI: 10.54250/ijls.v2i2.40

Abstract

Glebionis coronaria, formerly Chrysanthemum coronarium, is one of the medicinal herbs that belong to the Asteraceae family. This review paper aims to provide information regarding the botanical description, distribution, and phytochemical properties which contribute to the medicinal properties of Glebionis coronaria. Various studies have reported the presence of tannins, vitamins, macro- and microelements, beta-carotene, carbohydrates, protein, and other bioactive compounds in the plant’s essential oil, extract, or plant parts. Researchers have uncovered the potential pharmaceutical activities of the plant, including antibacterial, antifungal, antioxidant, anti-inflammatory, anti-cholesterol, to the potential anticancer properties. Based on the scientific evidence collected, G. coronaria has the potential to be used in many clinical areas for medicinal purposes. However, appropriate clinical testing should be pursued to evaluate the medicinal effects of this plant.
Phytochemical Screening, Therapeutic Benefits, and Adverse Effects of Citrus aurantifolia - A Review Chriscensia, Erika; Wibowo, Elizabeth Chrestella; Enriko, Gregorius; Wijaya, Owen Chrisfian; Sahamastuti, Agnes Anania Triavika
Indonesian Journal of Life Sciences 2020: IJLS Vol 02 No .02
Publisher : Indonesia International Institute for Life Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (487.287 KB) | DOI: 10.54250/ijls.v2i2.41

Abstract

Key lime or Citrus aurantifolia has been well known for its functions, either as food or medicine. This fruit has a greenish-yellow color with a sour and bitter taste and distributed initially from East Asia. This review summarizes the phytochemical screening, therapeutic effects, and adverse effects of key lime. Most parts of the plant contain phytochemicals, such as phenols, flavonoids, steroids, terpenoids, and alkaloids, with other varying compounds like saponin, tannin, anthraquinone, glycosides, and carbohydrates that may be due to the country where the plant is grown, or the extraction methods. Some studies have been conducted to evaluate the therapeutic effects of key lime, including antibacterial, antioxidant, anticancer or antitumor, anti-cholesterol, anti-larvae, anti-mosquito, antidiabetic, anti-inflammatory, and anticholinesterase. Key lime also may cause some adverse effects, such as phytophotodermatitis. It may lead to toxicity manifested in conditions such as edema, inflammation, or necrosis in some organs in the body, an increase in lymphocytes & liver enzymes, and a decrease in hemoglobin.
A Review of Botany, Phytochemical, and Pharmacological Effects of Dysphania ambrosioides Hewis, Lavisiony Gracius; Daeli, Giovanni Batista Christian; Tanoto, Kenjiro; Carlos, Carlos; Sahamastuti, Agnes Anania Triavika
Indonesian Journal of Life Sciences 2020: IJLS Vol 02 No .02
Publisher : Indonesia International Institute for Life Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (496.085 KB) | DOI: 10.54250/ijls.v2i2.42

Abstract

Traditional medicine is widely used worldwide due to its benefits and healthier components that these natural herbs provide. Natural products are substances produced or retrieved from living organisms found in nature and often can exert biological or pharmacological activity, thus making them a potential alternative for synthetic drugs. Natural products, especially plant-derived products, have been known to possess many beneficial effects and are widely used for the treatment of various diseases and conditions. Dysphania ambrosioides is classified as an annual or short-lived perennial herb commonly found in Central and South America with a strong aroma and a hairy characteristic. Major components in this herb are ascaridole, p-cymene, α-terpinene, terpinolene, carvacrol, and trans-isoascaridole. Active compounds isolated from this herb are found to exert various pharmacological effects including schistosomicidal, nematicidal, antimalarial, antileishmanial, cytotoxic, antibacterial, antiviral, antifungal, antioxidant, anticancer, and antibiotic modulatory activity. This review summarizes the phytochemical compounds found in the Dysphania ambrosioides, together with their pharmacological and toxicological effects.
Effectiveness And Safety Of Erdosteinie In Management Of Chronic Obstructive Pulmonary Disease (COPD): A Systematic And Meta-Analysis Yolanda, Lorensia; Gunawan, Catherine Keiko; Sumarpo, Anton; Sahamastuti, Agnes Anania Triavika; Cokro, Fonny
Jurnal Ilmu Kedokteran dan Kesehatan Vol 12, No 9 (2025): Volume 12 Nomor 9
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v12i9.20524

Abstract

Chronic obstructive pulmonary disease (COPD) is a chronic lung disease that cause limitation in the airflow and chronic inflammation. Erdosteine has been proposed as a potential therapeutic option for COPD management, based on its antioxidant activity and anti-inflammatory properties. The purpose of this systematic review and meta-analysis is to evaluate the effectiveness and safety of erdosteine in COPD patients. Multiple databases have been involved in the literature study following PRISMA guidelines, identifying randomized controlled trials (RCTs) that compared erdosteine with placebo. A total of seven studies were included in the qualitative analysis, and nine were analyzed quantitatively. Meta-analysis results indicated that erdosteine significantly improved forced expiratory volume in one second (FEV1), reduced reactive oxygen species (ROS) and 8-isoprostan levels, and lowered interleukin-8 (IL-8) concentrations. Subgroup analyses demonstrated greater benefits in patients with moderate to severe COPD (stage II/III). Safety analysis revealed that erdosteine was generally well-tolerated, with only mild adverse effects reported. However, study limitations included high heterogeneity and potential bias in some trials. Overall, the findings suggest that erdosteine is an effective and safe adjunct therapy for COPD.
Pektin Dari Daun Cincau Rambat (Cyclea barbata M.) dan Aplikasinya Dalam Bidang Biomedis: Review Sahamastuti, Agnes Anania Triavika
COMSERVA : Jurnal Penelitian dan Pengabdian Masyarakat Vol. 5 No. 4 (2025): COMSERVA: Jurnal Penelitian dan Pengabdian Masyarakat
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/comserva.v5i4.3342

Abstract

Pectin is a natural polysaccharide widely utilized in the food, pharmaceutical, and biomedical industries due to its biodegradable, biocompatible, and non-toxic properties. However, the current commercial sources of pectin remain limited to citrus peels and apple pomace, raising concerns about sustainability and raw material diversification. Therefore, exploration of alternative pectin sources is required. One promising candidate is Cyclea barbata Miers, a traditional Indonesian plant commonly used in refreshing beverages and herbal medicine. This study aims to assess the potential of Cyclea barbata leaves as an alternative pectin source by reviewing extraction yield, degree of esterification, and its possible applications. The method employed includes literature review and analysis of previous empirical data, which indicate that pectin yield ranges between 2.6–13.04% with a degree of esterification varying from 4–94.87%, depending on extraction conditions. These findings confirm that factors such as solvent type, pH, and temperature significantly influence pectin characteristics. The implications of this study highlight the potential of Cyclea barbata-derived pectin for various health-related applications, including pectin–chitosan membranes for wound dressings, emulsifiers, and biopolymer matrices in catalytic nanomaterial synthesis. With further research focusing on extraction optimization, comprehensive molecular characterization, and biological activity testing, Cyclea barbata pectin could be developed into a high-value local biomaterial that supports sustainability and self-reliance in natural-based industries.