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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Pengabdian Al-Ikhlas Journal of Medical Laboratory in Infectious and Degenerative Diseases
Anggitasari, Wima
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Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

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PENYULUHAN TENTANG KELOMPOK RISIKO TINGGI TERINFEKSI COVID-19 DAN EDUKASI PERILAKU HIDUP BERSIH DAN SEHAT SEBAGAI UPAYA PENCEGAHAN PENULARAN COVID-19 Pebriarti, Iski Weni; Anggitasari, Wima; Mayasari, Shinta; Susanti, Dhina Ayu
JURNAL PENGABDIAN AL-IKHLAS UNIVERSITAS ISLAM KALIMANTAN MUHAMMAD ARSYAD AL BANJARY Vol 10, No 3 (2024): AL-IKHLAS JURNAL PENGABDIAN
Publisher : Universitas Islam kalimantan MAB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31602/jpaiuniska.v10i3.9720

Abstract

Animo masyarakat dalam menggali informasi mengenai infeksi dan penyebaran COVID-19 mengalami peningkatan yang sangat signifikan sejak terdapat laporan kasus positif COVID-19 di Indonesia. Namun tidak banyak media massa online yang menginformasikan mengenai kelompok berisiko tinggi tertular COVID-19. Kecamatan Puger khususnya Desa Grenden adalah salah satu wilayah yang termasuk dalam Kabupaten Jember terdampak COVID-19 paling awal. Kegiatan pengabdian masyarakat dalam bentuk penyuluhan mengenai kelompok berisiko tinggi tertular COVID-19 diperlukan dalam upaya pencegahan penularan COVID-19 dan peningkatan wawasan masyarakat dalam menyikapi kelompok risiko tinggi tertular COVID-19. Kegiatan ini dihadiri oleh Kepala Dusun, kader posyandu, dan masyarakat khususnya yang termasuk dalam kelompok berisiko tinggi tertular COVID-19 seperti wanita hamil, penderita penyakit kronis tidak menular, penderita obesitas dan masyarakat dengan kebiasaan merokok. Materi yang disampaikan yaitu kelompok dengan risiko tinggi tertular COVID-19, enam langkah mencuci tangan dan lima waktu mencuci tangan, serta cara menggunakan masker dengan benar. Para peserta cukup antusias selama mengikuti kegiatan, terlihat dari beberapa peserta tampak berusaha mengikuti gerakan cuci tangan sambil menyanyi serta minat masyarakat untuk meminta leaflet dan stiker lebih banyak agar dapat diberikan kepada keluarganya.
The Effect of Boiled Mung Bean Seeds on Alanine Aminotransferase Levels in Rats (Rattus norvegicus L.) Induced by NaNO2 dwi ayu pratiwi, nabila; Mufidah, Hartalina; Imroatul Muflihah, Ahdiah; Anggitasari, Wima
Journal of Medical Laboratory in Infectious and Degenerative Diseases Vol. 2 No. 2 (2024): December
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/jmid.v2i2.26

Abstract

Background: Sodium nitrite is a chemical compound used in the coloring and preserving process of processed meat. Excess sodium nitrite entering the body can have clinical impacts on health, especially the liver. Disorders of the liver can be identified by increased levels of Alanine Aminotransferase. Mung beans contain antioxidants, a compound that has benefits as a hepatoprotection. Purpose: This study aims to determine the effect of Mung bean stew on Alanine aminotransferase levels in rats (Rattus norvegicus L.) with anemia before and after administration. Method: This research design is an experimental study with quantitative data collection. This study was conducted in June–July 2024. The sample in this study was rats (Rattus norvegicus), which were taken randomly using random sampling techniques. The Mung beans used in this study were Mung beans that had undergone an infusion process. After collecting data, the researcher processed the data using Paired sample-t test analysis, One-Way ANOVA, and Post Hoc Tukey using SPSS. Results: The Paired sample-t test for Alanine Aminotransferase levels in rats (Rattus norvegicus) with anemia showed sig>0.05 in all treatment groups. The test results of the average change in Alanine Aminotransferase levels before and after between groups showed a sig value <0.05. Conclusion: Based on this study, it can be concluded that Based on this research, it can be concluded that there is no effect of boiled Mung beans on Alanine aminotransferase levels.
Immunomodulator Effect of Cnidoscolus aconitifolius Leaves Extract on CD4+ and CD8+ Expression in Salmonella typhimurium infected mice Hidayati, Sholihatil; Susanti, Dhina Ayu; Destiawan, Rian Anggia; Muflihah, Ahdiah Imroatul; Handayani, Rizka; Anggitasari, Wima
Pharmaciana Vol. 14 No. 1 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i1.27050

Abstract

Typhoid fever is a common health problem in the community caused by Salmonella bacteria. The incidence rate of this infection will increase if a person's immune system is weakened. Plant extracts are generally considered to be potential immunomodulatory agents developed, which have smaller side effects. Research shows that Cnidoscolus aconitifolius leaves have medicinal properties including as hepatoprotective, antidiabetic, and anticardiovascular. The results of the antioxidant activity test show the results that Cnidoscolus aconitifolius leaves extract (CAE) has potential as an antioxidant with a very strong category. This study was conducted to determine the effect of giving Japanese papaya leaf extract on CD4+ and CD8+ expression in Babl/c mice induced by Salmonella typhimurium bacteria. The study was started by preparing 70% ethanol extract from Cnidoscolus aconitifolius leaves and preparing 30 Babl/C mice as experimental animals which were divided into 6 groups (healthy control, negative control, positive control and treatment group by giving CAE dose of 100 mg/kgbw, 200 mg/kgbw and 400 mg/kgbw). Induction was carried out by oral infection with Salmonella thypimurium bacteria. After 3 days the infected mice were treated orally once a day for 7 days. Evaluation of CD4+ and CD8+ expression was carried out using the flowcytometer method of the lymph organs. Data analysis was carried out by the Anova test followed by the post hoc test (Tukey) using the SPSS for Windows application. The results showed that giving CAE at doses of 100 mg/kgbw, 200 mg/kgbw and 400 mg/kgbw could increase the expression ratio of CD4+ and CD8+, whereas giving CAE at a dose of 400 mg/kgbw showed significantly different results (p<0.05) to the negative control. This shows that the CAE has potential as an immunomodulatory agent that can improve immune function.
Co-Authors AHDIAH IMROATUL MUFLIHAH dwi ayu pratiwi, nabila Hidayati, Sholihatil Mufidah, Hartalina Pebriarti, Iski Weni RIAN ANGGIA DESTIAWAN Rizka Handayani Shinta Mayasari Susanti, Dhina Ayu