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EFFECT OF Clitoria ternatea INFUSION ON THE NEUTROPHIL CELLS AND LYMPHOCYTE CELLS IN A MODEL OF Salmonella typhimurium INFECTION Anggia Destiawan, Rian; Imroatul Muflihah, Ahdiah; Hidayati, Sholihatil; Hariani Nurjanah, Mutia; Sandi Basuki, Aditya Occy; Asista Indarusanti, Delvia; Hayati, Farhatul; Amalia, Nabila
Jurnal Biosains Pascasarjana Vol. 26 No. 2 (2024): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v26i2.2024.185-192

Abstract

Salmonellosis is caused by infection with the bacterium Salmonella sp. which causes immune dysregulation and damage to digestive epithelial cells. So there is a need to increase immunity to fight Salmonella sp. The purpose of this study is to determine the effect of telang flower infusion on the number of Nuetrophophil cells and Lomfosyte cells on Salmonella typhimurium infection. The study was divided into 6 groups, negative, positive, Stimuno (0.26ml/20gBB), therapy 1 (0.25 ml/20gBB), therapy 2 (0.5 ml/20gBB), therapy 3 (1 ml/20gBB). Infusion making, Bacterial infection, infusa therapy, Giemsa staining, and 95% p-value data analysis. The results showed that there was a significant difference in the number of neutrophil cells in each group (p<0.05). Meanwhile, the number of lymphocytes after the anova test showed a significant increase in the number of lymphocytes (0.00<0.05). The conclusion of this study is that the infusion of telang flowers from low to high doses has an effect on increasing the number of neutrophil cells and lymphocyte cells
The Effect of Boiled Mung Bean Seeds on Alanine Aminotransferase Levels in Rats (Rattus norvegicus L.) Induced by NaNO2 dwi ayu pratiwi, nabila; Mufidah, Hartalina; Imroatul Muflihah, Ahdiah; Anggitasari, Wima
Journal of Medical Laboratory in Infectious and Degenerative Diseases Vol. 2 No. 2 (2024): December
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/jmid.v2i2.26

Abstract

Background: Sodium nitrite is a chemical compound used in the coloring and preserving process of processed meat. Excess sodium nitrite entering the body can have clinical impacts on health, especially the liver. Disorders of the liver can be identified by increased levels of Alanine Aminotransferase. Mung beans contain antioxidants, a compound that has benefits as a hepatoprotection. Purpose: This study aims to determine the effect of Mung bean stew on Alanine aminotransferase levels in rats (Rattus norvegicus L.) with anemia before and after administration. Method: This research design is an experimental study with quantitative data collection. This study was conducted in June–July 2024. The sample in this study was rats (Rattus norvegicus), which were taken randomly using random sampling techniques. The Mung beans used in this study were Mung beans that had undergone an infusion process. After collecting data, the researcher processed the data using Paired sample-t test analysis, One-Way ANOVA, and Post Hoc Tukey using SPSS. Results: The Paired sample-t test for Alanine Aminotransferase levels in rats (Rattus norvegicus) with anemia showed sig>0.05 in all treatment groups. The test results of the average change in Alanine Aminotransferase levels before and after between groups showed a sig value <0.05. Conclusion: Based on this study, it can be concluded that Based on this research, it can be concluded that there is no effect of boiled Mung beans on Alanine aminotransferase levels.