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All Journal Majalah Kedokteran Gigi Indonesia ODONTO Dental Journal Dentino: Jurnal Kedokteran Gigi TRIHAYU: Jurnal Pendidikan Ke-SD-an Jurnal Ilmiah Universitas Batanghari Jambi Pendas : Jurnah Ilmiah Pendidikan Dasar Jurnal Tarbiyah : Jurnal Ilmiah Kependidikan Darmabakti Cendekia: Journal of Community Service and Engagements Dentin An-Nadaa: Jurnal Kesehatan Masyarakat Jurnal Radiologi Dentomaksilofasial Indonesia (JRDI) Jurnal Sosial dan Teknologi EDUCASIA : Jurnal Pendidikan, Pengajaran, dan Pembelajaran Indo-MathEdu Intellectuals Journal Mamba'ul 'Ulum Jurnal Pengabdian Ilung (Inovasi Lahan Basah Unggul) Interdependence Journal of International Studies Jurnal Pengabdian Mandiri JOMPA ABDI: Jurnal Pengabdian Masyarakat SENTRI: Jurnal Riset Ilmiah Odonto dental journal Prosiding Temu Ilmiah Nasional Guru Shibyan: Jurnal Pendidikan Guru Madrasah Ibtidaiyah Jurnal Sosial Politik Humaniora Jurnal Ilmu Ekonomi Manajemen Perusahaan dan Bisnis
Aulia Azizah
Department Of Dental Public Health, Faculty Of Dentistry, Lambung Mangkurat University, Banjarmasin
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Analisis Hubungan Riwayat Keluarga dan Aktivitas Fisik dengan Kejadian Hipertensi di Kelurahan Indrasari Kabupaten Banjar Elsi Setiandari L.O; Ari Widyarni; Aulia Azizah
Jurnal Ilmiah Universitas Batanghari Jambi Vol 20, No 3 (2020): Oktober
Publisher : Universitas Batanghari Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33087/jiubj.v20i3.1094

Abstract

Hypertension is a condition in which a person has an increase in blood pressure above normal as indicated by the systolic and diastolic numbers on blood pressure checks using a blood pressure measuring device. The incidence of hypertension in Southeast Asia is 24.7% and 23.3% of Indonesia's population. The results of the initial survey of blood pressure measurements and interviews obtained the results of blood pressure checks from 30 community members with the criteria not suffering from hypertension as many as 3 people and those suffering from pre-hypertension were 9 people and those suffering from hypertension were 18 people. The purpose of this study was to determine the analysis of the relationship between family history and physical activity with the incidence of hypertension in Indrasari Village, Banjar Regency. This research was conducted with an analytic observational research design and method cross sectional. The population in this study were all hypertension sufferers in Indrasari who met the criteria as many as 87 people. Data analysis used univariate analysis using frequency distribution and bivariate analysis using chi-square test. The results showed that from the results of the chi square test, there was correlation between family history, physical activity and the incidence of hypertension , the value was obtained p = 0.001 <α 0.005 and the value obtained p = 0.001 <α 0.005 was. Based on the results of the research analysis, it can be concluded that there is a relationship between family history and physical activity with the incidence of hypertension in Indrasari Village, Banjar Regency.
HEALTH BEHAVIOR AND DENTAL CARRIES IN COASTAL COMMUNITY: LITERATURE REVIEW Koko Komarudin; Maharani Laillyza Apriasari; Aulia Azizah
ODONTO : Dental Journal Vol 8, No 2 (2021): December 2021
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.8.2.74-80

Abstract

ABSTRACTBackground: The important role of coastal communities is not directly in line with their living conditions, which are mostly poor. Dental caries is basically a disease that is also suffered by the general public in Indonesia, even in the world. RISKESDAS 2018 shows the prevalence of caries in Indonesia is 88.8%. Dental caries is caused by the bacterium Streptococcus mutans. People who live in coastal areas are at risk of suffering from dental caries. Brushing behavior also has a relationship with the incidence of dental caries. Method: All articles reviewed were obtained from Pubmed, Science Direct, and Google Scholar with a period of 10 years in full text. using the keywords behavior, caries, and coastal area.Result: Based on reviews from several journals, it was found that the brushing behavior of coastal communities was good, but the frequency of brushing teeth was not appropriate and the behavior of using drinking water had no known fluoride content. There are variations in the category of dental caries at the age level of people in coastal areas.Conclusion: Knowledge and healthy behavior can reduce the risk of dental caries related to the behavior of coastal communities, so that life productivity can be much better than ever.
RISK FACTORS OF ANGULAR CHEILITIS AT GUSTI HASAN AMAN DENTAL HOSPITAL SOUTH KALIMANTAN Aulia Azizah; Selviana Rizky Pramitha; Maharani Laillyza Apriasari
Dentino : Jurnal Kedokteran Gigi Vol 6, No 2 (2021)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v6i2.12002

Abstract

Background: The second highest burden of all diseases in world population includes infectious disease with a total of 28% cases. Angular cheilitis is an infectious condition on the corner of the mouth that may initiate masticatory, facial expression and speech dysfunction due to the involvement of orbicularis oris muscle surrounding the lips. The management of angular cheilitis comprises the elimination of causative microbes using antifungal agent. Therapeutic failure reveals the disregard of any related risk factor. Purpose: To analyze the risk factors of angular cheilitis in Gusti Hasan Aman Dental Hospital year 2019. Method: This study resorted analytical descriptive design of quantitative approach using cross-sectional method. Samples were 65 dental statuses of patients in Oral Medicine Clinic of Gusti Hasan Aman Dental Hospital year 2019. Result: Univariate data analysis presented the distribution of children category aged ≤ 18 years old (75.8%), men (54.8%), not consuming vegetable and fruit behaviour (46.8%), duration of treatment 1-7 days (56.4%), and incidence of angular cheilitis (75.8%). Fisher exact test unveiled the relationship between age and angular cheilitis (p<0.05) in which age ≤ 18 years old was 4.266 fold higher to experience angular cheilitis, while the relationship between gender and angular cheilitis (p<0.05) demonstrates the predilection of male with 4.853 fold at risk than female. Conclusion: Age and gender are risk factors in the incidence of angular cheilitis at Gusti Hasan Aman Dental Hospital year 2019.  Keywords : Age, Angular Cheilitis, Behavior, Gender
THE RELATIONSHIP BETWEEN THE SEVERITY OF MALOCCLUSION AND GINGIVAL STATUS IN STUDENTS OF SMPN 5 MARABAHAN Akhmad Aufayed Ma’rifatullah; Diana Wibowo; Aulia Azizah
Dentino : Jurnal Kedokteran Gigi Vol 6, No 1 (2021)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v6i1.10633

Abstract

ABSTRACTBackground: South Kalimantan experienced dental and mouth problems with a prevalence of 59,6%, so did Barito Kuala Regency with 68,66%. Malocclusion is a dental and oral health problem related to the disharmony between jaws and teeth. Many cases of malocclusion occur in children aged 12-14 years by 15,6% in the form of crowded teeth in South Kalimantan. Malocclusion is a factor that can cause food debris to stick to the interdental area between the crowded teeth, thus forming plaque accumulation. Plaque is the primary etiological factor that influences gingival status. Objective: This study aimed to determine the relationship between the severity of malocclusion and gingival status in students aged 12-14 years at SMPN 5 Marabahan. Method:  This study used analytic survey research with cross sectional research design. The research population was all students of SMPN 5 Marabahan aged 12-14 years who born in March 2005 - January 2008, amounting to 88 people. The minimum sample size which determined by the proportion estimation formula was 47 people. The used sampling technique was simple random sampling technique with inclusion and exclusion criteria. Results: The distribution frequency of the study showed mild malocclusion of 55,3% and mild inflammation of 57,4%. Spearman analysis test results on the severity of malocclusion based on Mal I and gingival status based on GI showed a significance value of p = 0,045 (p < 0,05). Conlclusion: It could be concluded that there was a relationship between the severity of malocclusion and gingival status in students aged 12-14 years at SMPN 5 Marabahan.Keywords:Gingival Index, Gingival Status, Malalignment Index, Malocclusion, Permanent Tooth Occlusion Stage 2.
THE EFFECTIVENESS OF THE ROLL TOOTH-BRUSHING TECHNIQUE TOWARD GINGIVAL HEALTH STATUS OF TOTALLY BLIND PEOPLE Jessica Laurent Citradi; Isnur Hatta; Aulia Azizah
Dentino : Jurnal Kedokteran Gigi Vol 7, No 1 (2022)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v7i1.13094

Abstract

Background: Gingivitis is an inflammatory reaction that occurs in gingival tissue. Based on 2018 RISKESDAS data, gingivitis case that occurs in Indonesia reaches 13,9%. The prevalence of gingivitis in South Kalimantan is higher than Indonesia’s, that is 14,2%. The bad habit of mantaining oral health causes plaque accumulation on the marginal gingiva, which resulting in gingivitis. The said condition also affects disabled people, one of which is blind people. Tooth brushing intervention can be done in various kind. One of the recommended methods is the roll technique that effectively cleans plaque and can mantain gum health. Purpose: To analyze the effectiveness of the roll tooth-brushing technique toward the gingival health status (gingival index) of totally blind people. Methods: This research used quasi-experimental research method with non-equivalent control group design. The sampling technique was using purposive sampling with total samples were 15 people. This research was conducted in 21 days with 9 times encounter. The time span of each encounter is once in every 2 days. Gingival index examination used gingival index. The data analysis in this research was using Mann Whitney Test. Result: The Mann Whitney test result shows that p-value is 0,018, which is smaller than the alpha value that is 0,05 (p<0,05) which means that there is a difference between the case group that was given with socialization and roll brushing technique and the control group that was not given the said socialization and treatment. Conclusion: The roll tooth-brushing technique is effective for gingival health status (gingival index) of totally blind people.
HUBUNGAN KECEMASAN DENTAL TERHADAP PERFORMANCE TREATMENT INDEX PADA ANAK KELAS 5-6 SDN BERANGAS TIMUR 1 KECAMATAN ALALAK KABUPATEN BARITO KUALA Muhammad Aulia Rifa Syarafi; Rosihan Adhani; Aulia Azizah
Dentin Vol 5, No 1 (2021)
Publisher : Universitas Lambung Mangkurat

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Abstract

ABSTRACTBackground: Dental anxiety is cause of psychological symptoms, as depression, fear, and discomfort regarding dental treatment. Prevalence of dental anxiety from population in several countries mostly in children with rates 5-20%. Feelings fear dental care become obstacle for dentists their efforts improve public dental health. This condition affects Performance Treatment Index, which is percentage number of teeth still filled with DMF-T number. PTI describes person's motivation to fill cavities in effort maintain permanent teeth. Based Riskesdas data, PTI in Barito Kuala is only 0.48%. Purpose: Analyzing relationship between dental anxiety Performance Treatment Index in children5-6 at SDN Berangas Timur 1, Barito Kuala Regency. Methods:This study used analytic observational study with cross sectional approach to 28 respondents. Research instrument for measuring anxiety using CFSS-DS questionnaire and PTI measurement using DMF-T index then calculated using PTI formula. Results: Research found results of dental anxiety with 22 children not anxious and 6 children anxious. Results with the good PTI category  obtained 1 child and poor 27 children. Result Spearman correlation test shows value p = 0.611. Conclusion: There was no relationship between dental anxiety and Performance Treatment Index in children at SDN Berangas Timur 1, Alalak District, Barito Kuala Regency.Keywords: Children, Dental Anxiety, Performance Treatment Index.ABSTRAKLatar Belakang: Kecemasan dental adalah penyebab dari gejala psikologis, seperti depresi, ketakutan, dan perasaan tidak nyaman terhadap perawatan dental. Prevalensi kecemasan dental dari populasi pada beberapa negara paling banyak  pada anak-anak dengan angka 5-20%. Perasaan takut terhadap perawatan gigi menjadi hambatan dokter gigi dalam usaha peningkatan kesehatan gigi masyarakat. Kondisi ini berpengaruh pada Performance Treatment Index, yaitu presentase jumlah gigi tetap ditambal terhadap angka DMF-T. PTI menggambarkan motivasi seseorang untuk menambalkan gigi berlubang dalam upaya mempertahankan gigi tetap. Berdasarkan data Riskesdas, PTI di Barito Kuala hanya 0,48%. Tujuan: Menganalisis hubungan antara Kecemasan dental terhadap Performance Treatment Index pada anak-anak Kelas 5-6 di SDN Berangas Timur 1 Kecamatan Alalak. Metode: Penelitian ini menggunakan penelitian observasional analitik dengan pendekatan Cross Sectional pada 28 responden. Instrumen penelitian pada pengukuran kecemasan menggunakan kuesioner CFSS-DS dan pengukuran PTI menggunakan indeks DMF-T kemudian dihitung menggunakan rumus PTI. Hasil: Penelitian ini mendapatkan hasil kecemasan dental dengan 22 anak tidak cemas dan 6 anak cemas. Hasil dengan kategori PTI baik diperoleh 1 anak dan buruk 27 anak. Hasil uji korelasi Spearman menunjukkan nilai p=0,611. Kesimpulan: Tidak terdapat hubungan antara Kecemasan dental terhadap Performance Treatment Index pada anak-anak di SDN Berangas Timur 1 Kecamatan Alalak Kabupaten Barito Kuala.Kata kunci: Anak-anak, Kecemasan dental, Performance Treatment Index
EFEKTIVITAS PENYULUHAN MENGGUNAKAN LAGU “GIGI SEHAT” TERHADAP PENURUNAN PLAK DI BARITO KUALA (Tinjauan SDN Barangas Timur 1 Kecamatan Alalak Kabupaten Barito Kuala) Faulina Windiyana; Rosihan Adhani; Aulia Azizah
Dentin Vol 4, No 1 (2020)
Publisher : Universitas Lambung Mangkurat

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Abstract

ABSTRAK           Background: Basic Health Research Results (Riskesdas) in 2018 showed the dental and oral health problems of the people in Indonesia reached 57.6%, while the dental and mouth problems in the province of South Kalimantan in children aged 5-9 years amounted to 71.17%, the daily brushing behavior amounted to 96.04% but the correct brushing time is only 4.97%. This indicates that there is still a lack of knowledge about how and when to brush the teeth properly and correctly so it needs an innovation in providing information in this is necessary. The counseling by using the songs is expected to change a person's behavior in ways and when they’re brushing their teeth properly. Objective: To analyze the effectiveness of the counseling using the "Healthy Teeth" song in students at the East Java 1 East Elementary School, Alalak District, Barito Kuala Regency. Method: Using an experimental and using the non equivalent control group design by dividing the respondents into two groups. The research was conducted at Barangas Blanket 1 Elementary School in Alalak Sub-district, Barito Kuala District, using the technique of probability sampling with positive sampling of 38 respondents. Results: The Whitney Mann test was found to have a significant significance of 0.018 <0.05, meaning that the effectiveness of using the "Healthy Teeth" song indeed decrease the index. Conclusion: Counseling using "Healthy Teeth" songs has effective effect in reducing plaque.Keywords: Counseling, Dental Plaque, SongABSTRAK          Latar belakang: Hasil Riset Kesehatan Dasar (Riskesdas) tahun 2018, masalah kesehatan gigi dan mulut masyarakat Indonesia sebesar 57,6%, sedangkan masalah gigi dan mulut di Provinsi Kalimantan selatan pada anak usia 5-9 tahun sebesar 71,17%, perilaku menyikat gigi setiap hari sebesar 96,04% tetapi waktu menyikat gigi yang benar hanya sebesar 4,97%. Hal tersebut menandakan bahwa masih kurangnya pengetahuan tentang cara dan waktu menyikat gigi yang baik dan benar sehingga perlunya suatu inovasi dalam memberikan informasi dalam hal tersebut. Penyuluhan menggunakan lagu diharapakan dapat merubah perilaku seseorang dalam cara dan waktu menyikat gigi yang baik dan benar. Tujuan: Menganalisis efektivitas penyuluhan menggunakan lagu “Gigi Sehat” pada siswa di SDN Barangas Timur 1 Kecamatan Alalak Kabupaten Barito Kuala. Metode: Menggunakan quasi eksperimental dengan rancangan non equivalent control grup design dengan membagi responden menjadi dua kelompok. Penelitian ini di laksanakan di SDN Barangas Timut 1 Kecamatan Alalak Kabupaten Barito Kuala dengan teknik pengambilan sampel menggunakan teknik non probability sampling dengan purposive sampling yaitu sebanyak 38 responden. Hasil: Uji Mann Whitney didapatkan nilai signifikansi sebesar 0,018 < 0,05, artinya terdapat efektivitas penyuluhan menggunakan lagu “Gigi Sehat” terhadap penurunan indeks plak. Kesimpulan: Penyuluhan menggunakan lagu “Gigi Sehat” efektif dalam menurunkan plak. Kata kunci:, lagu, penyuluhan, plak
HUBUNGAN ANTARA KEBIASAAN BURUK BERNAFAS MELALUI MULUT DENGAN TINGKAT KEPARAHAN MALOKLUSI PADA ANAK SEKOLAH DASAR Dinda Chesya; Diana Wibowo; Aulia Azizah
Dentin Vol 5, No 3 (2021)
Publisher : Universitas Lambung Mangkurat

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Abstract

ABSTRACTBackground: In Indonesia, malocclusion is a very high dental and oral health problem, accounting for about 80% of the population, ranks third after dental caries and periodontal disease. According to Basic Health Research (Riskesdas) data, South Kalimantan is an area with a high incidence of dental and oral health problems, which is around 59.6%, and cases of malocclusion in South Kalimantan are around 12%. This habit is most often done in elementary school children. Elementary school children aged 6-12 years need early diagnosis, because the permanent and primary teeth of this age group are fused in the oral cavity, and the occlusion is still temporary. If a malocclusion is found, it is easier to treat. Purpose: The purpose of the literature study was to determine the relationship between bad mouth breathing habits and the severity of malocclusion in elementary school children. Methods: All reviewed articles were obtained from searching Google Scholar, Pubmed and Science Direct data sources which have a maximum journal publication time of 10 years. Results: Bad habit of breathing through the mouth in elementary school children has a high percentage of 64.52%, and in children who breathe through the nose is 35.48%. The severity of malocclusion in children who have bad habits of mouth breathing is moderate malocclusion. The most cases of malocclusion are cases of class II division 1. Conclusion: There is a relationship between bad mouth breathing habits and the severity of malocclusion in elementary school children. Keywords: Bad habits, mouth breathing, malocclusion ABSTRAKLatar belakang : Di Indonesia, maloklusi merupakan masalah kesehatan gigi dan mulut yang sangat tinggi, terhitung sekitar 80% dari populasi, menempati urutan ketiga setelah karies gigi dan penyakit periodontal. Menurut data Riset Kesehatan Dasar (Riskesdas), Kalimantan Selatan merupakan daerah dengan insiden masalah kesehatan gigi dan mulut yang tinggi yaitu sekitar 59,6%, dan kasus maloklusi yang terjadi di Kalimantan Selatan sekitar 12%. Kebiasaan ini paling sering dilakukan pada anak sekolah dasar. Anak SD usia 6-12 tahun perlu diagnosis dini, karena gigi tetap dan gigi sulung kelompok usia ini menyatu dalam rongga mulut, dan oklusinya masih bersifat sementara. Jika ditemukan maloklusi, lebih mudah untuk dirawat. Tujuan: Tujuan studi literature  untuk mengetahui hubungan antara kebiasaan buruk bernafas melalui mulut dengan tingkat keparahan maloklusi pada anak sekolah dasar. Metode: Semua artikel yang direview diperoleh dari pencarian sumber data Google Scholar, Pubmed dan Science Direct yang memiliki rentang waktu penerbitan jurnal maksimal 10 tahun terakhir. Hasil: Kebiasaan buruk bernafas melalui mulut pada anak sekolah dasar memiliki persentase tinggi yaitu 64,52%, dan pada anak yang bernafas melalui hidung yaitu 35,48%. Tingkat keparahan maloklusi pada anak yang memiliki kebiasaan buruk bernafas melalui mulut yaitu maloklusi tingkat sedang. Kasus maloklusi yang paling banyak adalah kasus klas II divisi 1. Kesimpulan: Terdapat hubungan antara kebiasaan buruk bernafas melalui mulut dengan tingkat keparahan maloklusi pada anak sekolah dasar. Kata kunci: Bernafas melalui mulut, kebiasaan buruk, maloklusi
PENGARUH MINUMAN ENERGI DAN SUSU FERMENTASI TERHADAP PELEPASAN ION FOSFAT DAN FLUOR RESIN KOMPOSIT BIOAKTIF Irpansyah Irpansyah; Sherli Diana; Aulia Azizah
Dentin Vol 4, No 3 (2020)
Publisher : Universitas Lambung Mangkurat

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ABSTRACTBackground: Bioactive composite resin is a restoration material which has the ability to release calcium, phosphate, and fluorine ions. Bioactive composites release the ion at an acidic pH. The release of ions causes reduced activity of protease enzymes such as metalloproteinases (MMPs) and cathepsins which play a role in collagen degradation. This enzyme is one of the causes of decreasing the life of the bioactive composite resin with dentin. Purpose: The purpose of this study was to determine the effect of energy drinks and fermented milk on the release levels of phosphate ions and fluorine ions of bioactive composite resins. Methods: The bioactive composite resin specimens (ACTIVATM BioACTIVE-Restorative / USA) with a diameter of 15mm and 1mm thick (ISO 4149) were divided into 3 immersion groups. The release of phosphate ions was measured using a UV-VIS spectrophotometer and the release of fluorine ions was measured using a Lutron pH meter. Results: The largest release of phosphate ions occurred in the energy drink immersion group and the largest release of fluorine ions occurred in the fermented milk immersion group. Conclusion: The immersion group of energy drinks and fermented milk had an effect on the release of phosphate ions and fluorine ionsKeywords : Bioactive Composite Resin, Energy Drink, Fermented Milk, Fluorine Ion, Phosphate IonABSTRAK      Latar Belakang: Resin komposit bioaktif merupakan bahan restorasi yang memiliki kemampuan melepaskan ion kalsium, ion fosfat, dan ion fluor. Komposit bioaktif mengeluarkan ion pada pH yang asam. Pelepasan ion menyebabkan berkurangnya aktivitas enzim protease seperti metalloproteinases (MMPs) dan cathepsin yang berperan dalam degradasi kolagen. Enzim tersebut merupakan salah satu penyebab penurunan usia ikatan resin komposit bioakif dengan dentin. Tujuan: Tujuan penelitian ini adalah untuk mengetahui pengaruh minuman energi dan susu fermentasi terhadap kadar pelepasan ion fosfat dan ion fluor resin komposit bioaktif. Metode: Spesimen resin komposit bioaktif (ACTIVATM BioACTIVE-Restorative/USA) diameter 15mm dan tebal 1mm (ISO 4149) yang dibagi menjadi 3 kelompok perendaman. Pelepasan ion fosfat diukur menggunakan spektrofotometer UV-VIS dan pelepasan ion fluor diukur menggunakan pH meter Lutron. Hasil: Pelepasan ion fosfat terbesar terjadi pada kelompok perendaman minuman energi dan pelepasan ion fluor terbesar terjadi pada kelompok perendaman susu fermentasi. Kesimpulan: Kelompok perendaman minuman energi dan susu fermentasi memiliki pengaruh terhadap pelepasan ion fosfat dan ion fluor.Kata kunci: Ion Fluor, Ion Fosfat, Minuman Energi, Resin Komposit bioaktif, Susu Fermentasi.
UJI TOKSISITAS EKSTRAK KULIT BATANG ULIN (Eusideroxylon zwageri) TERHADAP SEL FIBROBLAS BHK-21 SECARA IN VITRO Ismi Natasya Salwa; I Wayan Arya Krishnawan Firdaus; Aulia Azizah
Dentin Vol 5, No 3 (2021)
Publisher : Universitas Lambung Mangkurat

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Abstract

ABSTRACTBackground: Antioxidants can come from plants that contain flavonoids such as ironwood. The bark of ironwood is declared effective to be used as a mouthwash because of the content of flavonoids, phenolics, tannins, saponins, alkaloids, and terpenoids. Ironwood bark extract to be used as an alternative material must be safe for oral tissues, so it is necessary to do a toxicity test. Objective: To analyze the toxic effect of ironwood bark extract through IC50 on BHK-21 fibroblast cells. Methods: This study was a pure laboratory experimental study with posttest-only control group design, consisting of 12 groups with 10 treatment groups given ironwood bark extract at concentrations of 5%, 15%, 25%, 35%, 45%, 55%. , 65%, 75%, 85%, and 95% and 2 control groups, namely cell control and media control. It was repeated 3 times so that the total sample was 36 samples. Toxicity test media used MTT assay which produced color absorbance and cell viability was calculated. Results: The results showed that the cell viability of the entire treatment group was >60% so it had no toxic effect. In addition, based on the IC50> 0.1%, which is 3.746%, it has no toxic effect on BHK-21 fibroblast cells. Conclusion: Ironwood bark extract at concentrations of 5%, 15%, 25%, 35%, 45%, 55%, 65%, 75%, 85%, and 95% had no toxic effect on BHK-21 fibroblast cells.   Keywords: BHK-21 fibroblast cells, Ironwood bark extract, , toxicity ABSTRAKLatar Belakang: Antioksidan dapat berasal dari tanaman yang mengandung flavonoid seperti ulin. Kulit batang ulin dinyatakan efektif untuk dijadikan obat kumur karena adanya kandungan flavonoid, fenolik, tanin, saponin, alkaloid, dan terpenoid.  Ekstrak kulit batang ulin untuk dijadikan sebagai bahan alternatif harus bersifat aman untuk jaringan rongga mulut sehingga perlu dilakukan uji toksisitas. Tujuan: Menganalisis efek toksik ekstrak kulit batang ulin melalui IC50 terhadap sel fibroblas BHK-21. Metode: Penelitian eksperimental laboratoris murni dengan posttest-only with control group design, terdiri dari 12 kelompok dengan 10 kelompok perlakuan yang diberi ekstrak kulit batang ulin konsentrasi 5%, 15%, 25%, 35%, 45%, 55%, 65%, 75%, 85%, dan 95% dan 2 kelompok kontrol, yaitu kontrol sel dan kontrol media. Dilakukan 3 kali pengulangan sehingga total sampel berjumlah 36 sampel. Media uji toksisitas menggunakan MTT assay yang menghasilkan absorbansi warna dan dilakukan perhitungan viabilitas sel. Hasil: Viabilitas sel seluruh kelompok perlakuan adalah >60% sehingga tidak memiliki efek toksik. Selain itu, berdasarkan nilai IC50>0,1% yaitu sebesar 3,746% tidak memiliki efek toksik terhadap sel fibroblas BHK-21. Kesimpulan: Ekstrak kulit batang ulin pada konsentrasi 5%, 15%, 25%, 35%, 45%, 55%, 65%, 75%, 85%, dan 95% tidak memiliki efek toksik terhadap sel fibroblas BHK-21. Kata kunci: Esktrak kulit batang ulin, sel fibroblas BHK-21, toksisitas.
Co-Authors Aaliyah, Della Alya Adilla, Bilqis Luthfi Afdel, Buna Ahmad Akhmad Aufayed Ma’rifatullah Alexandra, Frisca Amelia, Rizqy Anandita Ahmad Antung Lutfiliawan Ari Widyarni Aspriyanto, Didit Aulia Rahimah Ayu Azizah, Puty Azidi Irwan Azwar Fida Maulana Azzahra, Azizah Bambang Supeno, Bambang Bayu Indra Sukmana Choeroh, Niati Choirun Nisa Debby Saputera, Debby Dewi Nurdiana Diana Wibowo Dilla Mayarani Dinda Chesya Elsi Setiandari L.O Eva Naulia Faulina Windiyana Fitria, Novita Nanda Hamdani, Riky Hasanah, Asiyah Wardatul Hatta, Isnur Hayatunnufus Hayatunnufus Hery Haryanto Hidayah, Antung Nurul I Wayan Arya Krishnawan Firdaus Ika Kusuma Wardani Irpansyah Irpansyah Ismi Natasya Salwa Jessica Laurent Citradi Juli Harnida Purwaningayu Jumairoh, Siti Nok Kaspul Kaspul Koko Komarudin Kumala Dewi, Renie Kusumawati, Rani Labib Sajwandi M. Syabrina Madani, Pattika Reyhan Maharani Laillyza Apriasari Mahmudah, Istiyati Mohdari, Mohdari Muhammad Aulia Rifa Syarafi Muhammad Irfan Fanshuri Muhammad Luthfi Azzuhdi Muhammad Yunanda Anhar Muslimah, Chairul Nadia Deviyana Natasya Nurul Izzati Ngatmin Nida Amalia Nisaa’, Solikhatun Nurul Indah Qoriaty Nurwicaksono, Arya Dwi Oktiani, Beta Widya Pramitha, Selviana Rizky Pravitasari, Ayu Prima Putri, Bela Kusuma Rahmad Arifin Renie Kumala Dewi Ridoti, Afina Riky Riky Rosihan Adhani, Rosihan Sanjaya, Astria Mei Sari, Galuh Dwinta Sarifah, Norlaila Setyawardhana, Raden Harry Dharmawan Sherli Diana Sherly Nuralisa Sinay Sitepu, Alexander siti rahmah Sulistyowati Sulistyowati Sunardi Sunardi Tri Putri, Deby Kania Wahyu Widiyatmoko Wasilah, Elis Shofiyatul Widodo Widodo Wirawan, Rendy Yasmina Aulia Yuni Kusumawati Yuniarti Yuniarti Yunika Nur Indah Sari Z. Paramitha, Andi Irmaya