Article Per Year (5 Year)
p-Index From 2021 - 2026
0.659
P-Index
This Author published in this journals
All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Indonesian Journal of Pharmaceutical and Clinical Research International Journal Of Science, Technology & Management (IJSTM) Sciences and Clinical Pharmacy Research Journal
Haro, Ginda
Unknown Affiliation
Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Public Health Transportation

Published : 5 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 5 Documents
Search

 1 
PENETAPAN KADAR KALIUM, KALSIUM, NATRIUM DAN MAGNESIUM DALAM BUNGA NANGKA (Artocarpus eterophyllus Lam.) JANTAN SECARA SPEKTROFOTOMETRI SERAPAN ATOM Masfria, Masfria; Maulidar, Nanda Putri; Haro, Ginda
Media Farmasi: Jurnal Ilmu Farmasi Vol. 15 No. 2: September 2018
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v15i2.12659

Abstract

Nangka merupakan salah satu buah tropis yang keberadaannya tidak mengenalmusim. Tanaman nangka adalah tanaman berumah satu, artinya dalam satutanaman dapat dijumpai bunga jantan dan bunga betina. Mineral memegangperanan penting dalam pemeliharaan fungsi tubuh secara keseluruhan. Mineraldigolongkan dalalm mineral makro yang dibutuhkan dalam jumlah 100 mg seharidan mineral mikro kurang dari 100 mg sehari. Bunga nangka kurang populerdikalangan masyarakat dan belum ada penelitian terdahulu yang meneliti tentangkandungan dalam sampel tersebut. Tujuan penelitian ini adalah untuk mengetahuikandungan mineral kalium, kalsium, natrium dan magnesium dalam bunganangka jantan. Preparasi sampel dilakukan dengan proses dekstruksi kering.Penentuan kadar kalium, kalsium, natrium dan magnesium dilakukan denganmetode spektrofotometri serapan atom (SSA) masing-masing pada panjanggelombang 766,5 nm; 422,7 nm; 589,0 nm dan 285,2 nm dengan nyala udaraasetilen.Hasil penelitian menunjukkan bahwa kadar kalium, kalsium, natrium danmagnesium pada bunga nangka jantan yaitu [530,810] ± 2,760 mg/100g; [54,928]± 0,519 mg/100g; [16,087] ± 1,208 mg/100g dan [16,653]± 0,205 mg/100g
Cytotoxicity Activity of Ethanol Extract of Andaliman Fruits (Zanthoxylum acanthopodium DC.) towards 4T1 Breast Cancer Cells Rosidah, Rosidah; Hasibuan, Poppy Anjelisa Zaitun; Haro, Ginda; Satria, Denny
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 2 No. 2 (2019): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (888.661 KB) | DOI: 10.32734/idjpcr.v2i2.3220

Abstract

Breast cancer is one of the world's leading cause of death in women. Due to the resistance of chemotherapeutic agents, there is a continuous need to search of natural products with anticancer activity. The use of natural products is expected to increase the effectiveness and decrease side effect. The purpose of this study was to investigate the anticancer activity of ethanol extract of andaliman fruits (EEAF) towards 4T1 cells. Extracts were prepared by maceration using solvent ethanol 96%. 4T1 cells were grown in culture medium DMEM then given by EEAF and doxorubicin. Cytotoxic test in vitro was done by MTT method [3-(4,5-dimetiltiazol-2-il) -2.5 difeniltetrazolium bromide] which is then analyzed using SPSS 21. The results from this study showed that the cytotoxic results (IC50) after treatment with EEAF and doxorubicin were 54.48 ± 0.22 µg/mL dan 0.80 ± 0.02 µg/mL.Based on the result above, we conclude that EEAF has cytotoxic activity towards 4T1 cancer cells. Key words: andaliman fruits, Zanthoxylum acanthopodium DC., ethanol extract, breast cancer, 4T1 cell line.
Simultaneous Analysis of Tablets Content Vitamin C And Zinc In Visible Spectrophotometry Sulasmi, Sulasmi; Muchlisyam, Muchlisyam; Haro, Ginda
International Journal of Science, Technology & Management Vol. 4 No. 2 (2023): March 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i2.782

Abstract

Most drugs on the market contain multiple active ingredients, each of which is intended to enhance the drug's therapeutic effect and ease of administration. Determination of the levels of efficacious substances in drug preparations is essential for agencies that conduct drug determinations, such as the Food and Drug Supervisory Agency (BPOM) and the drug industry; therefore, a rapid and dependable analytical method, as well as relatively inexpensive and easily accessible tools and operational costs, are required. In practice, however, it can produce accurate and precise results. This research will be conducted by optimizing the solvent and simultaneously analyzing the levels of Vitamin C and Zinc in the tablet preparation without any separation step using visible spectrophotometry. Vitamin C and Zinc were found to be soluble in a mixture of methanol and water with a ratio of 50:50 after a single examination with the addition of the complexing agent dhitizon at a concentration of 0.1%, which produced a pink color. Calculation of Vitamin C and Zinc's linearity. The linearity value described is the correlation coefficient value for both Vitamin C and Zinc, which is very close to one, indicating an excellent relationship between the drug concentration and the absorbance value. This also suggests that absorbance will increase as concentration increases. The method validation requirements for linearity, accuracy, and precision as well as the limit of detection (LOD) and the limit of quantification (LOQ) were met by the analytical method validation with promising results.
Antioxidant, Antibacterial Activity, and Chemical Composition Analysis of Habbatussauda (Nigella sativa) Products Circulating in Medan City Using GC-MS Method Bangun, Sofia; Putra, Effendy; Haro, Ginda
Sciences and Clinical Pharmacy Research Journal Vol. 2 No. 4 (2026): January
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/scpr.v2i4.5116

Abstract

Habbatussauda (Nigella sativa) products marketed in Medan City, Indonesia were analyzed to determine their chemical composition, antioxidant capacity, and antibacterial activity. Antioxidant activity was evaluated using DPPH, ABTS, and FRAP assays with UV-Vis spectrophotometry, while antibacterial activity was assessed by measuring inhibition zones against Staphylococcus aureus. Chemical constituents were identified using Gas Chromatography–Mass Spectrometry (GC-MS). The results showed that oil-based Habbatussauda preparations exhibited significantly higher antioxidant capacity and antibacterial activity compared to powdered products across all tested methods. GC-MS analysis revealed the presence of major bioactive compounds, including thymoquinone, dithymoquinone, and p-cymene, which are known to contribute to antioxidant and antibacterial effects. The findings indicate that the formulation type strongly influences the bioactivity of commercial Habbatussauda products. Oil-based preparations demonstrate superior functional properties and may offer greater therapeutic potential than powdered forms. This study provides scientific evidence to support informed consumer selection and quality evaluation of Habbatussauda products.
FERMENTATION OF BITTER MUSTARD GREENS (Brassica juncea (L.) Czern.: PHYTOCHEMICAL SCREENING, PROXIMATE COMPOSITION, AND ISOLATION OF LACTIC ACID BACTERIA Nasri, Nasri; Cintya, Henni; Haro, Ginda; Silalahi, Jansen; Pakpahan, Gita Asima E.; Sitanggang, Sarah Novia S.; Sefira, Inka
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 8 No. 02 (2025): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v8i02.24242

Abstract

Fermented vegetables are widely consumed functional foods, but scientific data on traditionally fermented bitter mustard greens are still limited. This study aimed to evaluate the phytochemical profile and proximate composition of Brassica juncea after spontaneous fermentation and to isolate lactic acid bacteria (LAB) formed during the process. A laboratory experimental design was applied; bitter mustard greens were spontaneously fermented in brine for seven days at room temperature. Daily changes in pH and organoleptic characteristics were recorded. Phytochemical screening was performed on fresh and fermented samples (leaves, stems, brine). Proximate analysis included moisture, ash, acid-insoluble ash, crude fat, protein, and carbohydrates using AOAC methods. LAB were isolated on MRS–CaCO₃ agar and characterized phenotypically. Fermentation produced a progressive decrease in pH (from 5.0 to 2.9–3.3) accompanied by sour aroma and yellowish discoloration, indicating active lactic acid fermentation. Flavonoids, phenolics, and terpenoids were present in both fresh and fermented samples, although weaker reactions occurred in stems and brine. Proximate analysis revealed very high moisture content (88.76–95.20%), low protein (0.53–0.88%), low fat (5.03–5.50%), and low residual carbohydrates. LAB isolates (ASP-CF, ASP-B, ASP-D) were Gram-positive, catalase-negative, acid-producing, and non-H₂S-forming. In conclusion, traditional spontaneous fermentation of Brassica juncea produces a LAB-dominated fermented product that retains major phytochemical groups and exhibits proximate characteristics typical of fermented vegetables, supporting its potential as a functional food. Further molecular identification of LAB and quantitative metabolite profiling are recommended.
Co-Authors Bangun, Sofia Cintya, Henni Denny Satria, Denny Hasibuan, Poppy Anjelisa Zaitun Jansen Silalahi Masfria Maulidar, Nanda Putri Muchlisyam, Muchlisyam Nasri Nasri, Nasri Pakpahan, Gita Asima E. Putra, Effendy Rosidah Rosidah Sefira, Inka Sitanggang, Sarah Novia S. Sulasmi Sulasmi