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All Journal PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Journal Syifa Sciences and Clinical Research (JSSCR) Indonesian Journal of Community Dedication Diagnosis: Jurnal Ilmiah Kesehatan Medfarm: Jurnal Farmasi dan Kesehatan Indonesian Journal of Pharmaceutical Education Jurnal Pengabdian Masyarakat Berkarya Journal of Pharmaceutical Science and Herbal Technology
Indrayani, Ferna
STIKES Nani Hasanuddin Makassar
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Transportation Other

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In-vitro Anti-tuberculosis Activity and Phytochemical Screening of Lantana (Lantana camara L.) Flower Ferna Indrayani; Reski Yalatri Wirastuty
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia), Vol. 18 No. 02 Desember 20
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pharmacy.v18i2.9108

Abstract

This study aimed to determine the quality of raw materials, screen the phytochemicals, and evaluate the anti-tuberculosis activity of Lantana (Lantana camara L.) flower extract. The method used was direct observation in the laboratory. Lantana flower were processed into crude drugs and then extracted using 70% ethanol solvent. The extract obtained was evaluated for phytochemical screening and anti-tuberculosis activity assay. The in-vitro anti-tuberculosis activity assay was carried out using the Lowenstein-Jensen method. The results showed that the ethanolic extract of the Lantana flower was thick, dark brown with an aromatic odour and tasteless. The ethanolic extract of the Lantana flower showed a specific gravity of 1.0028 g/ml, the ethanol-soluble extractable of 1.15%, water-soluble extractable of 1.187%, the loss on drying of 8.21%, and total ash content of 9.40%. It contained chemical compounds such as alkaloids, flavonoids, tannins, saponins, steroids, and glycosides. The in-vitro results showed that extract at concentrations of 25, 50, and 100 µg/ml showed no colonies on the media from the 1st to the 6th week. Hence can be reported as susceptible. It can be concluded that the ethanol extract of the Lantana flower contains chemical compounds that potentially as anti-tuberculosis.
Co-Authors Adinda Nisa Shakila darwis darwis, darwis Datu, Jumiati Ernawati Ernawati Hasma Kartika Sari Wijayaningsih Mato, Rusni Mina La Isa, Wa Muhammad Asri Muin, Rahmatullah Muthmainnah B Mutmainna, Amriati Mutmainnah, Amriati Muzakkir Muzakkir Novianti Novianti Nurul Hikma Reski Yalatri Wirastuty Sakka, La Suryanita Wirastuty, Reski Yalatri