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Hubungan Mutasi Gen K-RAS terhadap Respon Terapi pada Pasien Kanker Kolorektal di RSUP Prof. DR. IGNG. Ngoerah Tahun 2017-2019. Bramantya, Putu Arya Rahadi; Wihandani, Desak Made; Dewi, Ni Nyoman Ayu; Ruma, I Made Winarsa
E-Jurnal Medika Udayana Vol 13 No 3 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i03.P13

Abstract

K-RAS is one of the most frequently mutated genes found in colorectal cancer cases. The K-RAS gene has about 30%-40% contribution to the formation of colorectal cancer. This research is an analytic observational study with a cross-sectional design to explain the characteristics of patients with colorectal cancer at Prof. dr. IGNG. Ngoerah 2017-2019 and assessed the relationship between K-RAS gene mutations and response to therapy. The results of the chi-square test showing a significant relationship between the type of KRAS gene mutation and the response to therapy where p=0.035 (p<0.05). This shows that there is a significant relationship between mutations in the K-RAS gene in colorectal cancer and the response to therapy in colorectal cancer patients at Prof. Dr. IGNG. Ngoerah General Hospital in 2017-2019.
EFEKTIVITAS JUS BUAH SEBAGAI TERAPI KOMPLEMENTER TERHADAP TEKANAN DARAH PASIEN HIPERTENSI : A SYSTEMATIC REVIEW OF RANDOMIZED CONTROLLED TRIALS Mahendra, Bayu; Surudarma, I Wayan; Wihandani, Desak Made; Ruma, I Made Winarsa
E-Jurnal Medika Udayana Vol 11 No 9 (2022): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2022.V11.i9.P17

Abstract

Hypertension treatment can be helped through complementary therapies, one of which is fruit juices. This study aimed to systematically review the evidence from various study regarding the effect of fruit juices on blood pressure in hypertensive patients and the types of fruit juices that are proven to be effective in reducing hypertension.This study is systematic review. Literature searching was conducted in four electronic databases, namely CINAHL, EMBASE, Pubmed, and Sciencedirect with the phrase fruit juices AND (hypertension OR blood pressure). Studies obtained from searching will be selected based on a screening title and abstract, eligibility criteria, and assesment risk of bias. The results of the study obtained 21 final studies with RCT research designs that passed the screening with complete eligibility criteria. However, the studies with valid results only amounted to 8 studies. These data show that as many as 5 studies prove fruit juices can reduce blood pressure in hypertensive patients and 3 other studies have stated the opposite. Thus, it can be concluded that there is strong evidence that fruit juices has a significant effect on reducing blood pressure in hypertensive patients. Fruit juices that have been shown to be effective are orange juice and queen garnet plum juice
Relationship between leg muscle explosive power and lay-up shoot ability wahyu, I Made Wahyu Pranatha Putra; Dewi, Anak Ayu Nyoman Trisna Narta; Wahyuni, Nila; Ruma, I Made Winarsa
Physical Therapy Journal of Indonesia Vol. 5 No. 1 (2024): January-June 2024
Publisher : Universitas Udayana dan Diaspora Taipei Medical University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/ptji.v5i1.168

Abstract

Background: Lay-up shoot is one of the basic techniques that a basketball athlete must master to be a winner. The shooting technique involves jumping and dribbling the ball as close as possible into the ring. This study aimed to describe the relationship between leg muscle explosive power and lay-up shoot ability. Methods: This research was a descriptive study with a correlational design that used a total sampling technique that targeted all students who were basketball club members at Public Senior High School 8 Denpasar concerning inclusion and exclusion criteria. A vertical jump test measured leg muscle explosive power, and the lay-up shoot ability was measured by doing a lay-up shoot ten times. Results: The results showed a relationship between leg muscle explosive power and the lay-up shoot ability of the students. Most students have above-average legs, muscle explosive power, and good lay-up shooting skills. The better the leg's muscle explosive power, the better the lay-up shoot ability, which shows that the leg muscle explosive power is positively correlated with the lay-up shoot ability Conclusion: This study found a significant relationship between leg muscle explosive power and ability lay-up shoot students at the basketball club Public Senior High School 8 Denpasar.