Erfi Prafiantini
Departemen Ilmu Gizi Fakultas Kedokteran Universitas Indonesia Indonesian Hydration Working Group - FKUI

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Journal : World Nutrition Journal

Partially Hydrolyzed Whey Protein: A Review of Current Evidence, Implementation, and Further Directions Badriul Hegar; Zakiudin Munasir; Ahmad Suryawan; I gusti Lanang Sidhiarta; Ketut Dewi Kumara Wati; Erfi Prafiantini; Irene Irene; Yvan Vandenplas
World Nutrition Journal Vol. 5 No. 1 (2021)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V05.i1.0008

Abstract

Background: Human milk is known to be the best nutrition for infants as it provides many health benefits. For non-breastfed infants, cow's milk based infant formula is the most optimal option to provide the needed nutrition. However, approximately 2-5% of all formula-fed infants experience cow’s milk allergy during their first year of life. Partially hydrolyzed whey formula (pHF-W) have been widely recommended to prevent the development of allergic disease in infants. However, according to epidemiological data, approximately half of the infants developing allergy are not part of the at-risk group.Objectives and Methods: This article aims to review the effects of pHF-W in preventing allergy, especially atopic disease, in all non-breastfed infants, as well as the safety aspect of pHF-W if used as routine formula. The role of pHF-W in the management of functional gastro-intestinal (GI) disorders is also reviewed.Results: Several clinical studies showed that pHF-W decrease the number of infants with eczema. The strongest evidence is provided by the 15-year follow up of the German Infant Nutritional Intervention study which showed reduction in the cumulative incidence of eczema and allergic rhinitis in pHF-W (OR 0.75, 95% CI 0.59-0.96 for eczema; OR 0.67, 95% CI 0.47-0.95 for allergic rhinitis) and casein extensively hydrolysed formula  group (OR 0.60, 95% CI 0.46-0.77 for eczema; OR 0.59, 95% CI 0.41-0.84 for allergic rhinitis), compared to CMF as a control, after 15 years of follow-up. pHF-W was also found to be beneficial in the management of functional GI disorders such as regurgitation, constipation and colic.Conclusions: The use of pHF-W in allergic infants has been recommended in various guidelines across the countries, as a primary prevention of allergic disease. One pHF-W has been approved by the US FDA and the European Commission's European Food Safety Authority (EFSA) for its safety and suitability as a routine infant formula for all healthy infants. According to the data obtained in the management of functional GI disorders, pHF-W is better tolerated than formula with intact protein. Further studies assessing the effect of routine use of pHF-W in a larger population of non-breastfed infants should also be conducted, in order to observe any potential harm and to determine the benefit and cost-effectiveness ratio.
Pattern of fiber intake in different socio-demographic settings among elderly in Jakarta, Indonesia and its associated factors Nanda Fauziyana; Erfi Prafiantini; Novi Silvia Hardiany
World Nutrition Journal Vol. 4 No. 2 (2021): Volume 04 Issue 2, August 2021
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V04.i2.0002

Abstract

Introduction Despite many health benefits from dietary fiber, inadequate intake is prevalent among elderly population. This study aims to obtain the pattern of fiber intake in different socio-demographic backgrounds among elderly in Jakarta area, Indonesia and its’ associated factors. Methods: A cross-sectional study was conducted among elderly aged > 60 years in 5 community health center across Jakarta province. A total of 126 elderly were interviewed using two non-consecutive 24-h dietary recall methods to obtain dietary intake data. Socio-demographic backgrounds on age, sex, education, income, marital status, and energy intake were assessed using structured questionnaire. Mann-Whitney or independent t-test was performed to measure the different of fiber intake in each socio-demographic variable. Linear regression test was performed to analyze the variables that associated with fiber intake. Results: Majority of 98.4% of elderly have total fiber intake <80% of Indonesian Recommended Dietary Allowance (RDA) with average intake of 6.6 g/d. Lower fiber intake was significantly found in females, widowed/separated, have lower education and income, and have inadequate energy intake. Factors associated with total fiber intake were income (adjusted β=0.20, p=0.01) and energy intake adequacy (adjusted β=0.65 p=0.00). Conclusion: Fiber intake among elderly in urban area is inadequate and the pattern was worse in the low socio-demographic settings. By this finding, it is important to give priority to the socially disadvantages group when formulating nutrition intervention policy in this population setting.
Protein and iron intake adequacy among high school girls in Depok, Indonesia Meirina Khoirunnisa; Yoga Devaera; Umi Fahmida; Fiastuti Witjaksono; Erfi Prafiantini
World Nutrition Journal Vol. 4 No. 2 (2021): Volume 04 Issue 2, August 2021
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V04.i2.0004

Abstract

Introduction: Iron deficiency anemia is the most common type of anemia among adolescent girls. The prevalence of anemia among pregnant women increased from 2013 to 2018, and females age 15-24 years had the highest prevalence of anemia. Therefore, knowing the baseline status of protein and iron intake —particularly animal-sourced protein as the main source of heme iron—is important to design future intervention program. Thus, this study was aimed to assess the protein and iron intake adequacy of High School girls in Depok, Indonesia. Methods: 211 girls from Senior High School in Depok, Indonesia participated in this study. Subjects were selected using a multi-stage random sampling method. A questionnaire was administered to obtain general characteristics. Dietary intake data were obtained using a 3-day non-consecutive 24hr recall 1 weekend 2 weekdays interview. Anthropometric status was measured and calculated. Data were analyzed using IBM SPSS Statistics 20. Spearman’s correlation (significance p<0.05) was used to determine the factors related to protein and iron intake. Results: This population had inadequate intake of energy (97.2%), protein (59.7%), and iron (98.6%). However, intake of fat was higher than recommended in 59.2% of participants. Protein and iron intake were not correlated with age, father’s education, mother’s education, and the number of household member.
The effect of intermittent fasting 5:2 on IL-6 levels in obese male employees in Jakarta Diva Octavia Sarah; Karima Yudhistina; Erfi Prafiantini; Lily Indriani Octovia; Novi Silvia Hardiany
World Nutrition Journal Vol. 7 No. 01 (2023): Volume 07 Issue 1, August 2023
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/10.25220/WNJ.V07.i1.0009

Abstract

Background: Obesity is a condition of excessive fat accumulation in adipose tissue. This condition causes endothelial damage, increase macrophage infiltration, and inflammation in adipose tissue. Inflammation happens due to the increase of interleukin-6 (IL-6) as a proinflammatory cytokine which responsible for the occurrence of chronic diseases. Intermittent fasting is a potentially effective method for losing weight and suggested can reduce levels of proinflammatory cytokines. Objective: The aim of this study is to determine the effect of 5:2 intermittent fasting on IL-6 cytokine levels in obese employees in Jakarta. Methods: This study used a cross-sectional method conducted on 50 healthy male employees aged 19–52 years with a body mass index (BMI) ≥25 kg/m2. Subjects were divided into two groups, the 5:2 intermittent fasting group and the non-fasting group. Intermittent fasting 5:2 was observed every Monday and Thursday for eight weeks. IL-6 levels were obtained through examination using an enzyme-linked immunosorbent assay (ELISA) method. Statistical analysis was performed by Mann Whitney and Kruskal Wallis test. Results: The results showed that the median of IL-6 levels decreased in fasting group from 5,10 (1.06–9.81) pg/mL to 4.64 (1.00–13.39) pg/mL and increased in non-fasting group from 3.65 (1.17–38.70) pg /mL to 6.35 (2.44–19.86) pg/mL, but the change was not significant. Conclusion: Intermittent fasting 5:2 tend to decrease IL-6 levels in obese male employees in Jakarta although the change of IL-6 level was not significant.