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All Journal Sari Pediatri Jurnal Gizi Klinik Indonesia Amerta Nutrition World Nutrition Journal Makara Journal of Health Research
Erfi Prafiantini
Departemen Ilmu Gizi Fakultas Kedokteran Universitas Indonesia Indonesian Hydration Working Group - FKUI
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health Other

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Partially Hydrolyzed Whey Protein: A Review of Current Evidence, Implementation, and Further Directions Badriul Hegar; Zakiudin Munasir; Ahmad Suryawan; I gusti Lanang Sidhiarta; Ketut Dewi Kumara Wati; Erfi Prafiantini; Irene Irene; Yvan Vandenplas
World Nutrition Journal Vol. 5 No. 1 (2021)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V05.i1.0008

Abstract

Background: Human milk is known to be the best nutrition for infants as it provides many health benefits. For non-breastfed infants, cow's milk based infant formula is the most optimal option to provide the needed nutrition. However, approximately 2-5% of all formula-fed infants experience cow’s milk allergy during their first year of life. Partially hydrolyzed whey formula (pHF-W) have been widely recommended to prevent the development of allergic disease in infants. However, according to epidemiological data, approximately half of the infants developing allergy are not part of the at-risk group.Objectives and Methods: This article aims to review the effects of pHF-W in preventing allergy, especially atopic disease, in all non-breastfed infants, as well as the safety aspect of pHF-W if used as routine formula. The role of pHF-W in the management of functional gastro-intestinal (GI) disorders is also reviewed.Results: Several clinical studies showed that pHF-W decrease the number of infants with eczema. The strongest evidence is provided by the 15-year follow up of the German Infant Nutritional Intervention study which showed reduction in the cumulative incidence of eczema and allergic rhinitis in pHF-W (OR 0.75, 95% CI 0.59-0.96 for eczema; OR 0.67, 95% CI 0.47-0.95 for allergic rhinitis) and casein extensively hydrolysed formula  group (OR 0.60, 95% CI 0.46-0.77 for eczema; OR 0.59, 95% CI 0.41-0.84 for allergic rhinitis), compared to CMF as a control, after 15 years of follow-up. pHF-W was also found to be beneficial in the management of functional GI disorders such as regurgitation, constipation and colic.Conclusions: The use of pHF-W in allergic infants has been recommended in various guidelines across the countries, as a primary prevention of allergic disease. One pHF-W has been approved by the US FDA and the European Commission's European Food Safety Authority (EFSA) for its safety and suitability as a routine infant formula for all healthy infants. According to the data obtained in the management of functional GI disorders, pHF-W is better tolerated than formula with intact protein. Further studies assessing the effect of routine use of pHF-W in a larger population of non-breastfed infants should also be conducted, in order to observe any potential harm and to determine the benefit and cost-effectiveness ratio.
Pattern of fiber intake in different socio-demographic settings among elderly in Jakarta, Indonesia and its associated factors Nanda Fauziyana; Erfi Prafiantini; Novi Silvia Hardiany
World Nutrition Journal Vol. 4 No. 2 (2021): Volume 04 Issue 2, August 2021
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V04.i2.0002

Abstract

Introduction Despite many health benefits from dietary fiber, inadequate intake is prevalent among elderly population. This study aims to obtain the pattern of fiber intake in different socio-demographic backgrounds among elderly in Jakarta area, Indonesia and its’ associated factors. Methods: A cross-sectional study was conducted among elderly aged > 60 years in 5 community health center across Jakarta province. A total of 126 elderly were interviewed using two non-consecutive 24-h dietary recall methods to obtain dietary intake data. Socio-demographic backgrounds on age, sex, education, income, marital status, and energy intake were assessed using structured questionnaire. Mann-Whitney or independent t-test was performed to measure the different of fiber intake in each socio-demographic variable. Linear regression test was performed to analyze the variables that associated with fiber intake. Results: Majority of 98.4% of elderly have total fiber intake <80% of Indonesian Recommended Dietary Allowance (RDA) with average intake of 6.6 g/d. Lower fiber intake was significantly found in females, widowed/separated, have lower education and income, and have inadequate energy intake. Factors associated with total fiber intake were income (adjusted β=0.20, p=0.01) and energy intake adequacy (adjusted β=0.65 p=0.00). Conclusion: Fiber intake among elderly in urban area is inadequate and the pattern was worse in the low socio-demographic settings. By this finding, it is important to give priority to the socially disadvantages group when formulating nutrition intervention policy in this population setting.
Protein and iron intake adequacy among high school girls in Depok, Indonesia Meirina Khoirunnisa; Yoga Devaera; Umi Fahmida; Fiastuti Witjaksono; Erfi Prafiantini
World Nutrition Journal Vol. 4 No. 2 (2021): Volume 04 Issue 2, August 2021
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V04.i2.0004

Abstract

Introduction: Iron deficiency anemia is the most common type of anemia among adolescent girls. The prevalence of anemia among pregnant women increased from 2013 to 2018, and females age 15-24 years had the highest prevalence of anemia. Therefore, knowing the baseline status of protein and iron intake —particularly animal-sourced protein as the main source of heme iron—is important to design future intervention program. Thus, this study was aimed to assess the protein and iron intake adequacy of High School girls in Depok, Indonesia. Methods: 211 girls from Senior High School in Depok, Indonesia participated in this study. Subjects were selected using a multi-stage random sampling method. A questionnaire was administered to obtain general characteristics. Dietary intake data were obtained using a 3-day non-consecutive 24hr recall 1 weekend 2 weekdays interview. Anthropometric status was measured and calculated. Data were analyzed using IBM SPSS Statistics 20. Spearman’s correlation (significance p<0.05) was used to determine the factors related to protein and iron intake. Results: This population had inadequate intake of energy (97.2%), protein (59.7%), and iron (98.6%). However, intake of fat was higher than recommended in 59.2% of participants. Protein and iron intake were not correlated with age, father’s education, mother’s education, and the number of household member.
Profil Asupan Minum pada Anak Prasekolah di Daerah Urban dan Rural di Indonesia dan Faktor-faktor yang Memengaruhinya Titis Prawitasari; Bernie Endyarni Medise; Diana Sunardi; Dewi Friska; Erfi Prafiantini; Rizki Yusrini Pohan; Budi Wiweko
Sari Pediatri Vol 22, No 4 (2020)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp22.4.2020.236-42

Abstract

Latar belakang. Asupan minum yang kurang akan berdampak terhadap performa fisik dan kognitif serta dapat menimbulkan manifestasi klinis, seperti pusing, lesu, dan gangguan konsentrasi. Anak memiliki proporsi cairan tubuh yang lebih tinggi dibandingkan dewasa. Hingga saat ini belum ada data mengenai kecukupan asupan minum anak prasekolah di Indonesia.Tujuan. Mengetahui kecukupan asupan minum anak prasekolah di daerah urban dan rural di Indonesia.Metode. Penelitian dengan desain potong lintang dilakukan pada bulan Januari-Maret 2016 di Jakarta dan Maluku pada anak usia 36-72 bulan. Perhitungan jumlah cairan dilakukan dengan mencatat jumlah yang diminum dalam 7 Day-Fluid Diary Record. Asupan minum total ditentukan berdasarkan jumlah yang dikonsumsi dari semua kategori dan sesuai dengan angka kecukupan gizi (AKG) 2019.Hasil. Sebanyak 585 anak mengikuti penelitian ini dengan median asupan minum adalah 1133,1 (85-2991,4) mL/hari dan jenis asupan paling tinggi adalah air putih. Subjek yang tinggal di daerah urban mempunyai faktor risiko lebih rendah untuk mengalami asupan minum yang kurang (RR=0,580; 95%IK: 0,418-0,807; p=0,001). Demikian pula semakin muda usia subjek, maka semakin kecil kemungkinan untuk mengalami kejadian asupan minum yang kurang (RR =0,497; 95%IK: 0,356-0,694; p=0,000).Kesimpulan. Rerata asupan minum anak usia prasekolah di Indonesia sedikit lebih rendah dari anjuran AKG. Anak prasekolah berusia ≥54 bulan dan anak yang tinggal di area rural lebih berisiko mengalami kekurangan asupan minum.
Pengaruh puasa intermiten 5:2 terhadap kadar malondialdehida pada karyawan pria dewasa dengan obesitas Karima Yudhistina; Erfi Prafiantini; Novi Silvia Hardiany
Jurnal Gizi Klinik Indonesia Vol 17, No 4 (2021): April
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.61765

Abstract

Effect of intermittent fasting 5:2 on plasma malondialdehyde levels in adult male employees with obesityBackground: Obesity is a major risk factor for various non-communicable diseases such as type 2 diabetes mellitus and cardiovascular disease. In obesity, the free radical product will be produced, such as malondialdehyde (MDA) which plays a role in the pathogenesis of various diseases. Intermittent fasting (IF) is an alternative way to reduce free radical levels in the body therefore it can prevent complications of obesity. However, the effect of IF on MDA level in an obese adult male in Jakarta has not been reported.Objective: The objective of this study was to determine the effect of IF on malondialdehyde levels in adult male employees with obesity in Jakarta.Methods: This study used a randomized controlled clinical trial. The subjects were men aged 19-59 years with a body mass index (BMI) ≥ 25 kg/m2, divided into fasting and control groups, each group consists of 25 subjects. Intermittent fasting 5:2 is calorie restriction up to 20-25% was done every Monday and Thursday, and not allowed to eat and drink during 14 hours of fasting. Before the intervention, both groups were given education about balanced nutrition. Association of intermittent fasting with MDA and catalase was analyzed by means of difference formula with a significance limit of 5%.Results: MDA levels post-intervention significantly decreased compared to the pre-intervention both in the fasting group [1,3(0,9-2) nmol/mL to 0,4(0,3-0,6) nmol/mL] and in the control groups [1,4(0,9-1,9) nmol/mL to 0,5(0,3-0,7) nmol/mL]. MDA level post-intervention in the fasting group was significantly lower (p<0,05) compared to the control group.Conclusions: Intermittent fasting 5:2 during 8 weeks can decrease MDA levels in adult males with obesity in Jakarta.
Diet Quality Profile among Urban Elderly in Jakarta during COVID-19 Pandemic in Indonesia Nanda Fauziyana; Novi Silvia Hardiany; Erfi Prafiantini
Amerta Nutrition Vol. 6 No. 2 (2022): AMERTA NUTRITION
Publisher : Universitas Airlangga, Kampus C, Mulyorejo, Surabaya-60115, East Java, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v6i2.2022.191-197

Abstract

Background: Insulin resistance is a condition in which insulin cannot take up glucose, increasing blood glucose. Elderly people are more exposed to insulin resistance, requiring dietary interventions that extend longevity. Trehalose, a naturally occurring sugar, showed potentially reduce insulin resistance which can be measured using the HOMA-IR (Homeostatis Model Assessment-Insulin Resistance) index. Objectives: This study aimed to assess HOMA-IR levels as a parameter of insulin resistance in old rats after giving trehalose sugar. Methods: Experimental research with 28 male Wistar rats (Rattus novergicus) was separated into 4 groups, the control group of young rats (Group A), the control group of old rats (Group B), a group of old rats that were given 2% Trehalose solution (Group C), and a group of old rats that given 2% sucrose solution (Group D) that observed for 8 weeks. Results: The results showed differences in HOMA-IR levels (p<0.001) between old and young subjects. The intervention in Group C was optimal in reducing levels of HOMA-IR (p<0.001) by 18.2% compared with the old control, while Group D increased levels of HOMA-IR by 14.3% (p<0.001) compared with the old control. The age of the subjects with HOMA-IR level is positively correlated (p<0.001; r=0.721) and the weight of subjects with the HOMA-IR level is also positively correlated (p<0.001; r=0.698), indicating that the older and the greater weight of subject resulting in the bigger of HOMA-IR value. Conclusion: Trehalose is effective in reducing HOMA-IR levels as a parameter of insulin resistance in old rats.
The Effect of Intermittent Fasting 5: 2 on Body Weight and Insulin Resistance among Obese Employees in Jakarta Anni Rahmawati; Fiastuti Witjaksono; Erfi Prafiantini
Amerta Nutrition Vol. 5 No. 2 (2021): AMERTA NUTRITION
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v5i2.2021.158-165

Abstract

Latar Belakang: Prevalensi penduduk dewasa di Indonesia yang obesitas mengalami peningkatan dari tahun ke tahun. Sementara itu, angka obesitas pada pekerja, terutama di perkotaan juga makin meningkat. Puasa intermiten dapat menjadi alternatif solusi dalam tatalaksana obesitas untuk menurunkan berat badan, sehingga parameter metabolik lainnya seperti resistensi insulin juga bisa menurun.Tujuan: Mengetahui efek puasa intermiten 5:2 terhadap perubahan berat badan resistensi insulin pada karyawan obesitas di JakartaMetode: Penelitian ini menggunakan rancangan uji klinis acak terkontrol. Sampel penelitian ialah karyawan di Jakarta yang  berusia 19-59 tahun,memiliki IMT ≥ 25 kg/m2, dan memiliki lingkar pinggang ≥ 90 cm. Sampel dibagi menjadi kelompok intervensi (n=25) dan kelompok kontrol (n=25). Kelompok intervensi diminta untuk berpuasa pada hari senin dan kamis selama 8 minggu, sementara kelompok kontrol melanjutkan pola makan seperti biasa. Tidak terdapat pembatasan kalori pada kedua kelompok.  Pengumpulan data melalui proses wawancara, pengukuran tubuh serta pemeriksaan laboratorium.  Analisis data untuk melihat perbedaan rerata antar kelompok dengan menggunakan uji t tidak berpasangan atau uji Mann-Whitney, sementara untuk melihat perubahan dalam kelompok menggunakan uji t berpasangan atau Wilcoxon.Hasil: Perubahan berat badan pada kelomok intervensi ialah -0,8kg (-5,1- 2,2), sementara perubahan berat badan pada kelompok kontrol -0,3kg(-7,9 – 2,8). Perubahan kadar HOMA-IR pada kelompok intervensi ialah -0,29 (-17,78 – 6,84), sementara perubahan kadar HOMA-IR pada kelompok kontrol -0,46 (-18,94 – 10,55). Tidak terdapat perbedaan bermakna rerata perubahan berat badan dan resistensi insulin pada kelompok yang berpuasa dibandingkan kelompok yang tidak melakukan puasa (p>0,05). Terdapat perbedaan berat badan pada kelompok intervensi dengan p = 0,026.Kesimpulan: Tidak terdapat perbedaan perubahan berat badan dan kadar HOMA-IR pada kelompok yang berpuasa dibandingkan kelompok yang tidak melakukan puasa, walaupun perbedaan berat badan pada kelompok intervensi turun bermakna. Perlu dilakukan promosi dan edukasi kesehatan  secara berkala untuk meningkatkan pengetahuan dan mengubah perilaku karyawan akan gizi seimbang sehingga dapat mencegah terjadinya obesitas serta penyakit metabolik terkait obesitas.
Association of Parenting Style and Mindful Eating with Sodium Intake among Adolescents in Indonesia Pamungkas, Rizqy Amanatul Husna; Prafiantini, Erfi; Chandra, Dian Novita
Makara Journal of Health Research Vol. 27, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Most adolescents have an excessive sodium intake associated with hypertension and cardiovascular disease (CVD). Parents have an important role in controlling adolescents’ nutritional intake, including sodium, through healthy eating. Mindful eating is considered healthy eating with the potential to control nutritional intake. This study aims to analyze the association of parenting style and mindful eating with sodium intake among adolescents. Methods: This cross-sectional study involved adolescents aged 15–18 years. Sodium intake was measured by repeated 24-hour food recall. Parenting style was examined with a validated parenting style and dimensions questionnaire self-administered by the adolescent parent. Mindful eating was evaluated using a mindful eating questionnaire (MEQ) self-administered by the adolescent. Data were analyzed using Kruskal–Walls and Spearman correlation. Results: Parenting style has no significant association with sodium intake, and mindful eating has a negatively significant correlation with sodium intake (p < 0.05; r = −0.17). Conclusions: Parenting style has no direct association with sodium intake. However, mindful eating has a significant association with sodium intake and parenting style. Mindful eating shows potential as a mediator between parenting style and sodium intake.
Association of vitamin E intake and malondialdehyde (MDA) levels with cognitive function in elderly residing at the Budi Mulia Tresna Werdha nursing home, East DKI Jakarta Ria Angelia Putri; Novi Silvia Hardiany; Erfi Prafiantini
World Nutrition Journal Vol. 10 No. 1 (2026): WNJ. Volume 10 Issue 1, Agustus 2026
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V10.i1.0015

Abstract

Background: Cognitive dysfunction is one of the health problems associated with elderly. Oxidative stress is thought to play a role in the neurodegenerative process through increased production of free radicals that cause nerve cell damage. Vitamin E is an antioxidant that protects cell membranes from oxidative damage, whereas malondialdehyde (MDA) is a biomarker of oxidative stress produced by lipid peroxidation. The objective of this study is to analyze the association of vitamin E intake and MDA levels with cognitive function among elderly residents of Budi Mulia 1 Nursing Home in DKI Jakarta, Indonesia. Methods: This secondary study employed a cross-sectional design using data derived from a primary study investigating the association between zinc intake, superoxide dismutase activity, and cognitive function among elderly. A total of 85 participants met the inclusion and exclusion criteria. Vitamin E intake was assessed using a Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ), plasma MDA levels were measured from stored plasma samples, and cognitive function was evaluated using the Indonesian version of the Montreal Cognitive Assessment (MoCA-Ina). Results: The median age of the participants was 69 years (range: 60–91 years). The median vitamin E intake, plasma MDA level, and cognitive function score were 3.7 mg/day (2.5–3.8), 2.85 nmol/mL (1.88–6.77), and 16 (1–30), respectively. No significant association was found between vitamin E intake and cognitive function (r = 0.027; p = 0.806), nor between plasma MDA levels and cognitive function (r = 0.096; p = 0.380). Conclusion: There was no significant association between vitamin E intake or plasma MDA levels and cognitive function among elderly.
Co-Authors Ahmad Suryawan Akmal P. Suprapto Anni Rahmawati Anwar S. Ibrahim Aryo Tedjo Badriul Hegar Bernie Endyarni Medise Budi Wiweko Chandra, Dian Novita Dendi Priyanto Dewi Friska Diana Sunardi Fiastuti Witjaksono I gusti Lanang Sidhiarta Irene Irene Kardha, Putu Chandra Dewi Karima Yudhistina Ketut Dewi Kumara Wati Lestari Octavia Meirina Khoirunnisa Nanda Fauziyana Nanda Fauziyana Novi Silvia Hardiany Pamungkas, Rizqy Amanatul Husna Pramesthi, Indriya Laras Ria Angelia Putri Rina Agustina Rizki Yusrini Pohan Rizqi, Nov Sari, Okky Lupita Sholihah, Lini Anisfatus Subari A. Riyanto Titis Prawitasari, Titis Umi Fahmida Yoga Devaera Yudhistina, Karima Yvan Vandenplas Zakiudin Munasir