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Ethanol-based solvent system for recovery antioxidant activity Centella asiatica L. Urban and its application in sleep-deprived Rats Wardatun, Sri; Sofihidayati, Trirakhma; Afifah, Nida; Juhroh, Juju
Pharmaciana Vol. 14 No. 2 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i2.27277

Abstract

Antioxidants have the ability to eliminate free radicals by donating electrons to oxidants. Preclinical and clinical studies show that Centella asiatica L. Urban has antioxidant activity. Ethanol was the best solvent for extracted antioxidant compounds from Centella asiatica L. Urban. The concentration of ethanol solvents effect to the compounds extracted and its antioxidant activities. The objective of study to determine ethanol based solvent systems for best recovery of antioxidant activities and in vivo antioxidant activity of the most active extract using stress induced sleep-deprived rats with glutathione (GSH) concentration parameters. Ethanol based solvent system show different recovery antioxidant activity of Centella asiatica L. Urban. Ethanol 70% had the highest recovery of antioxidant activity with an IC50 value of 76.76 ppm. Ethanol 70% Centella asiatica L. Urban extract given in sleep-deprived rats at 300 mg/kg were not significantly different in glutathione levels from those group rats that received the positive control solution (ascorbic acid). The 70% ethanol extract of C. asiatica L. Urban has the potential to ameliorate the stress induced by sleep deprivation.
Komunikasi Menjadi Salah Satu Cara Efektif Dalam Pendidikan di TK An Nizam Barus, Melianna Br; Pulungan, Nailah; Afifah, Nida; Nasution, Arifah; Anggraini, Elya Siska
Madani: Jurnal Ilmiah Multidisiplin Vol 2, No 6 (2024): Madani, Vol 2, No. 6 2024
Publisher : Penerbit Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.12172327

Abstract

Effective communication is a fundamental element in the learning process. The interactions that exist between educators and students, as weel as between students, become the basis for transferring knowledge, instilling values, and developing character. However, in practice, effective communication in education still often encounters obstacles. This can be caused by various factors, such as educators’ lack of understanding of effective communication strategies, lack of preparation and practice, as weel as cultural and language barriers. This research aims to analyze the importance of effective communication in education. identifying key elements in effective communication in education. Developing strategies to build effective communication in education. This research uses qualitative methods. The results of the research show that effective communication in education has a very important role in increasing learning motivation, understanding of the material, and active participation of students.
Pengaruh Konsentrasi Ragi dan Lama Waktu Fermentasi terhadap Kadar Protein, Kadar Serat dan Sensori Tempe Segar Moulia, Mona Nur; Ahmad, Shaf Rijal; Afifah, Nida
Teknotan: Jurnal Industri Teknologi Pertanian Vol 18, No 3 (2024): TEKNOTAN, Desember 2024
Publisher : Fakultas Teknologi Industri Pertanian

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jt.vol18n3.5

Abstract

Tempe dibuat dari bahan dasar kacang kedelai yang difermentasi dengan jenis kapang Rhizopus sp. Proses fermentasi dan konsentrasi ragi yang tepat menghasilkan tempe yang tinggi protein, serat kasar dan antioksidan. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh konsentrasi ragi dan lamanya fermentasi terhadap karakteristik mutu dan sensori tempe. Penelitian ini menggunakan Rancangan Acak Kelompok (RAK) dengan faktor konsentrasi ragi dan lama fermentasi. Konsentrasi ragi yang digunakan yaitu 0,2 g; 0,4 g; dan 0,8 g (K1, K2, K3) dan lama fermentasi yaitu 36 jam, 44 jam dan 52 jam (L1, L2, L3). Analisis tempe terdiri dari kadar protein menggunakan metode Kjeldahl, serat kasar menggunakan metode Gravimetri dan uji sensori (warna, aroma, tekstur, kekompakan, citarasa dan daya terima) dengan 30 orang panelis tidak terlatih. Semakin sedikit pemberian konsentrasi ragi dan semakin cepat waktu fermentasi maka nilai protein yang dihasilkan semakin tinggi (17,86%), sebaliknya kadar serat semakin tinggi dengan semakin banyak konsentrasi ragi yang diberikan dan semakin lama waktu fermentasi (9,08%). Berdasarkan uji sensori pada tempe segar, secara keseluruhan tempe dengan konsentrasi ragi 0,4g dan lamanya fermentasi 44 jam memperoleh tingkat kesukaan yang lebih tinggi dibandingkan dengan perlakuan yang lain.
Ethanol-based solvent system for recovery antioxidant activity Centella asiatica L. Urban and its application in sleep-deprived Rats Wardatun, Sri; Sofihidayati, Trirakhma; Afifah, Nida; Juhroh, Juju
Pharmaciana Vol. 14 No. 2 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i2.27277

Abstract

Antioxidants have the ability to eliminate free radicals by donating electrons to oxidants. Preclinical and clinical studies show that Centella asiatica L. Urban has antioxidant activity. Ethanol was the best solvent for extracted antioxidant compounds from Centella asiatica L. Urban. The concentration of ethanol solvents effect to the compounds extracted and its antioxidant activities. The objective of study to determine ethanol based solvent systems for best recovery of antioxidant activities and in vivo antioxidant activity of the most active extract using stress induced sleep-deprived rats with glutathione (GSH) concentration parameters. Ethanol based solvent system show different recovery antioxidant activity of Centella asiatica L. Urban. Ethanol 70% had the highest recovery of antioxidant activity with an IC50 value of 76.76 ppm. Ethanol 70% Centella asiatica L. Urban extract given in sleep-deprived rats at 300 mg/kg were not significantly different in glutathione levels from those group rats that received the positive control solution (ascorbic acid). The 70% ethanol extract of C. asiatica L. Urban has the potential to ameliorate the stress induced by sleep deprivation.