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All Journal The Indonesian Journal of Infectious Diseases J-KESMAS: Jurnal Kesehatan Masyarakat PREPOTIF : Jurnal Kesehatan Masyarakat JK Unila (Jurnal Kedokteran Universitas Lampung) Proceedings of the International Conference on Nursing and Health Sciences Jurnal Penyakit Dalam Indonesia
Syarif, Syahrizal
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health

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Penyakit Gagal Ginjal Kronis Stadium 5 Berdasarkan Determinan Umur, Jenis Kelamin, dan Diagnosa Etiologi di Indonesia Tahun 2018 Nasution, Syahrul Hamidi; Syarif, Syahrizal; Musyabiq, Sofyan
Jurnal Kedokteran Universitas Lampung Vol 4, No 2 (2020): JK UNILA
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jk unila.v4i2.2885

Abstract

Penyakit gagal ginjal kronik telah menjadi isu yang sangat penting dalam beberapa tahun terakhir karena frekuensinya meningkat dan tingginya biaya yang ditimbulkannya semakin dilihat sebagai masalah kesehatan masyarakat utama yang terkait dengan kematian dini yang berkaitan dengan implikasi sosial dan ekonomi yang penting. Selain diagnosis dan deteksi dini, pengetahuan terkait penyakit gagal ginjal kronik (GGK) berdasarkan determinan umur, jenis kelamin, dan diagnosa etiologi di Indonesia tahun 2018 ini dapat dijadikan bahan/bukti ilmiah dalam perencanaan, pelaksanaan program, evaluasi program, dan menentukan skala prioritas pada program pencegahan dan pengobatan penyakit ginjal kronik di Indonesia yang merupakan tujuan dilakukannya penelitian ini. Jenis penelitian ini adalah penelitian literatur riview. Populasi target adalah seluruh pasien gagal ginjal kronik stadium 5 di Indonesia. Populasi terjangkau pada penelitian ini adalah seluruh pasien gagal ginjal kronik stadium 5 yang terdata di kumpulan data Indonesian Renal Registry (IRR) tahun 2018. Sampel penelitian ini adalah seluruh (total sampling) pasien gagal ginjal kronik stadium 5 yang terdata di kumpulan data Indonesian Renal Registry tahun 2018.Penelitian ini dilakukan pada bulan Maret-Juni 2020 dengan menggunakan data IRR tahun 2018. Berdasarkan data IRR 2018 jenis kelamin laki-laki merupakan pasien GGK terbanyak sebesar 57% (36.976) dan perempuan sebesar 43% (27.608). Determinan usia, kelompok usia ≤44 tahun sebanyak 26,04% dan kelompok usia ≥45 tahun merupakan yang terbanyak sebesar 73,96%. Berdasarkan diagnosa etiologi, hipertensi merupakan yang terbanyak dan menempati urutan pertama sebesar 36%, diikuti nefropati diabetik 28%, tidak diketahui 12%, glomerulopati primer 10%, lain-lain 5%, pielonefritis kronik 3%, nefropati obstruktif 3%, nefropati asam urat, ginjal polikistik, dan nefropati lupus masing-masing sebesar 1%. Kesimpulan kelompok usia ≥45 tahun, berjenis kelamin laki-laki, dan memiliki hipertensi merupakan determinan terbanyak pasien GGK di Indonesia tahun 2018.Kata Kunci : Gagal ginjal kronik stadium 5, Indonesian Renal Registry, penyakit gagal ginjal kronik,.
Comparative Evaluation of Alpha-Fetoprotein Serum inHepatocellular Carcinoma Patients with Non-Viral Etiology Aprilicia, Gita; Bantas, Krisnawati; Syarif, Syahrizal; Kalista, Kemal Fariz
Jurnal Penyakit Dalam Indonesia Vol. 8, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction. Non-viral etiology of hepatocellular carcinoma (HCC) now needs attention. Hepatocellular carcinoma which was caused by hepatitis B and hepatitis C could be controlled in the national program, while HCC from non-B non-C etiology has become a further concern with the with the increased of metabolic syndrome. Serum alpha-fetoprotein is a tumor marker commonly used for screening for HCC in patients with liver cirrhosis (LC). However, in HCC patients with nonviral etiology, AFP serum tends to be normal. This study aimed to evaluate the performance of AFP serum based in HCC and LC patient with non-viral etiology and to evaluate the factors associated with elevated AFP. Methods. Data HCC from registry at Cipto Mangunkusumo Hospital in the period August 2015 to December 2019 were collected. Patients with liver cirrhosis (LC) were taken as the control group. The etiology of liver disease is determined by viral serological examination. Non-viral etiology was defined as a patient who was anti-HCV negative and HBsAg negative. Differences in AFP levels were evaluated by using the Mann Whitney test. Performance of serum AFP in viral and non-viral etiologies were evaluated by receiver operation character (ROC). The factors associated with an increase in AFP by a threshold of 10 ng/ml were evaluated by multivariate analysis using logistic regression. Results. There were 295 HCC patients and 155 LC patients who were included in this study. Non-viral etiology was found in 16.1% of LC group and 14.9% of HCC group. The median serum AFP in HCC patients was higher than in LC patients, 187.50 ng/ml vs. 4.60 ng/ml, p 5 cm was 2.89 (95% CI: 1.56 - 3.67; p value 0.001). Conclusions. AFP Serum is low in HCC patients with non-viral etiology. The increase of serum AFP above 10 ng/ml is associated with etiology of viral hepatitis and tumor size.
FAKTOR YANG MEMPENGARUHI PASIEN TUBERKULOSIS RESISTAN OBAT YANG TIDAK MEMULAI PENGOBATAN: LITERATURE REVIEW Rizkiyani, Indri; Syarif, Syahrizal
J-KESMAS: Jurnal Kesehatan Masyarakat Vol 10, No 1 (2024): J-KESMAS Volume 10 Nomor 1, Mei 2024
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Al Asyariah Mandar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35329/jkesmas.v10i1.4973

Abstract

Drug-resistant tuberculosis (DR TB) patients who have been diagnosed but not enrolled to treatment could be a source of primary transmission and the risk of increasing DR TB cases in the community. The aim of this literature review is to determine the factors that influence pre-treatment lost to follow up of DR TB patients by searching the literature through Google Scholar, ScienceDirect, ProQuest and PubMed which was published in the period 2016 to 2023 with the keywords "drug resistant tuberculosis", "treatment initiation", “enrollment rate”, and “pre-treatment lost to follow up”. Seven articles were obtained of which three research articles came from China, two from South Africa, one from India, and one from Ethiopia. Factors that influence DR TB patients not starting treatment include age, economic status, drug sensitive TB treatment status, inadequate health service infrastructure, lack of experienced clinicians, health seeking behavior, and health system delays. The low rate of DR TB treatment initiation requires special attention, both in terms of health services provided by the government and support from the community, in order to break the chain of transmission in the community.
A Literature Review: Analysis of Clinical Pathway Implementation for Covid-19 Patients Chohan, Zakir; Syarif, Syahrizal; Sudaryo, Mondastri Korib
Proceedings of the International Conference on Nursing and Health Sciences Vol 5 No 2 (2024): July-December 2024
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/picnhs.v5i1.3003

Abstract

Clinical pathway is a guideline for evidence-based medical care, best service, patient expectations for communication facilities, multidisciplinary activities, patients, families, as documentation, monitoring, recording, variants, providing the necessary resources and results. Objective to determine the extent to which the implementation of the clincal pathway is applied and is beneficial to Covid-19 patients.Method: The method used was to conduct a critical analysis of research articles, regarding the implementation of clinical pathways for Covid-19 patients during the pandemic taken from the Pub Med and PMC databases with the keywords used: Implementation AND clinical pathway AND Covid-19 AND pandemic. The number of articles analysed was 116 and then obtained 3 relevant articles. Results: Clinical pathway is useful in facilitating the lack of access to patient examination services, supporting examinations, and also treatment. Clinical pathways that are incorporated into E-medical records help clinicians to get the latest information and improve adherence to evidence-based guidelines so as to produce good results for services. Clinical pathways are needed as guidelines in the application of diagnostic and management of Covid-19 disease in children.Conclusion: Clinical pathway implementation is needed in services, especially in access gaps, up-to-date information, clinician compliance, diagnostic guidelines and management of Covid-19 patients to get good evidence-based.
FAKTOR YANG BERHUBUNGAN DENGAN KELENGKAPAN TERAPI PENCEGAHAN TUBERKULOSIS SENSITIF OBAT DI KOTA JAKARTA BARAT TAHUN 2020 - 2023 Budiarti, Indah; Syarif, Syahrizal
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 9 No. 1 (2025): APRIL 2025
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v9i1.43132

Abstract

Tatalaksana TBC laten sesuai rekomendasi WHO tahun 2018 dengan Program Terapi Pencegahan Tuberkulosis (TPT) baru dilaksanakan tahun 2020 di Indonesia. Capaian Angka Kelengkapan TPT di DKI Jakarta 76.7% dari target 80%. Studi ini untuk memberikan gambaran karakteristik penerima TPT di Kota Jakarta Barat, termasuk faktor yang berhubungan kelengkapan TPT sensitif obat. Penelitian ini menggunakan desain kohort retrospektif dengan sumber data sekunder dengan total sampel 890 memenuhi kriteria inklusi dan eksklusi dari total 1555 penerima TPT dari Sistem Informasi Tuberkulosis (SITB) tahun 2020 - 2023. Hasil univariat didapatkan proporsi kelengkapan TPT Jakarta Barat adalah 94%. Hasil analisis multivariat didapatkan hasil peluang kelengkapan terapi signifikan pada waktu setelah 72 hari terapi untuk hubungan durasi pemberian TPT 3 bulan (aHR: 8.68; 95% CI: 6.29 – 11.97) dibanding paduan 6 bulan, jenis pemberi layanan TPT puskesmas lebih berpeluang lengkap (aHR: 1.76; 95% CI: 1.06–2.89) dibanding pasien rumah sakit, dan bila pemeriksaan TST positif (aHR: 1.26: 95% CI 1.05 – 1.49) dibanding pasien yang tidak dilakukan TST. Kesimpulan dari penelitian ini yakni penguatan implementasi program TPT secara holistic perlu dilakukan dengan mempertimbangkan alokasi dukungan sesuai karakteristik pasien yang lebih berpeluang melengkapi TPT, agar program TPT ini dapat berjalan seefektif dan seefisien mungkin.
Detection of Tuberculosis Cases Among Correctional Facility Inmates in Indonesia Karlinda, Amelia Yuri; Syarif, Syahrizal
The Indonesian Journal of Infectious Diseases Vol. 11 No. 1 (2025): The Indonesian Journal of Infectious Diseases
Publisher : Rumah Sakit Penyakit Infeksi Prof Dr. Sulianti Saroso

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32667/ijid.v11i1.404

Abstract

Background: Tuberculosis (TB) remains a major health burden in correctional facilities, with incidence rates significantly higher than in the general population due to confined and overcrowded environments. Systematic screening is an essential approach to detecting TB cases early; however, national data on the effectiveness of systematic screening in Indonesian correctional facilities remains limited. Methods: This cross-sectional study utilized data from TB screening of 206,337 inmates across 376 correctional facilities in Indonesia conducted between July and December 2023. Screening included symptom assessment and chest X-ray (CXR) examination, followed by rapid molecular testing (TCM) for suspected cases. Analysis was performed to evaluate the proportion of TB case detection and the association between screening results and TB diagnosis. Results: A total of 4,881 TB cases were identified, with a detection proportion of 2.37% and a prevalence rate of 2,369 per 100,000 inmates. Systematic use of CXR successfully identified TB cases, including among asymptomatic inmates, with 25.99% of inmates showing abnormal CXR findings confirmed to have TB. There was a statistically significant association between CXR results and TB case detection (p < 0.001). Conclusion: Systematic screening combining symptom assessment, CXR, and TCM is effective in enhancing early TB case detection in correctional facilities. These findings reinforce the need for widespread implementation of comprehensive screening strategies, strengthening of healthcare services, and infection control measures to reduce the TB burden in Indonesian correctional settings.
HUBUNGAN OBESITAS SENTRAL DENGAN HIPERTENSI DERAJAT 1 PADA WANITA DI INDONESIA (ANALISIS DATA SKI 2023) Octaryana, Octaryana; Syarif, Syahrizal
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 9 No. 2 (2025): AGUSTUS 2025
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v9i2.47303

Abstract

Hipertensi merupakan masalah kesehatan masyarakat yang utama dan menjadi penyebab signifikan morbiditas serta mortalitas di seluruh dunia. Berdasarkan Survei Kesehatan Indonesia (SKI) tahun 2023, prevalensi hipertensi pada penduduk usia 18 tahun ke atas di Indonesia mencapai 30,8%. Hipertensi derajat 1 merupakan fase awal hipertensi yang perlu mendapat perhatian khusus melalui deteksi dini agar dapat mencegah komplikasi serius. Selain itu, obesitas sentral juga merupakan faktor risiko penting yang berkontribusi pada peningkatan tekanan darah dan kejadian hipertensi, terutama pada wanita. Prevalensi obesitas sentral pada wanita di Indonesia pada tahun 2023 dilaporkan sebesar 54,1%. Penelitian ini bertujuan untuk menganalisis hubungan antara obesitas sentral dengan hipertensi derajat 1 pada wanita di Indonesia. Metode penelitian yang digunakan adalah desain cross-sectional dengan pendekatan analisis multivariat untuk mengendalikan variabel kovariat seperti umur. Hasil penelitian menunjukkan prevalensi hipertensi derajat 1 pada wanita sebesar 10,79%. Wanita yang mengalami obesitas sentral memiliki risiko 1,992 kali lebih tinggi (Adjusted POR = 1,992; 95% Confidence Interval: 1,762 – 2,250) untuk menderita hipertensi derajat 1 dibandingkan dengan wanita tanpa obesitas sentral setelah dikontrol variabel umur. Berdasarkan temuan ini, diperlukan upaya serius dalam menurunkan prevalensi obesitas sentral melalui penerapan intermitten fasting dan peningkatan aktivitas fisik secara rutin sebagai strategi pencegahan hipertensi di kalangan wanita Indonesia.
Co-Authors Aprilicia, Gita Chohan, Zakir Indah Budiarti, Indah Karlinda, Amelia Yuri Kemal Fariz Kalista, Kemal Fariz Krisnawati Bantas Mivtahurrahimah, Mivtahurrahimah Octaryana, Octaryana Rizkiyani, Indri Sofyan Musyabiq Wijaya Sudaryo, Mondastri Korib Syahrul Hamidi Nasution