Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Jurnal Kedokteran Diponegoro Medica Hospitalia
Afriliana, Liza
Unknown Affiliation
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
THE EFFICACY OF TOPICAL CLINDAMYCIN GEL ON SEVERITY DEGREE OF ACNE VULGARIS AMONG FEMALE COLLEGE STUDENTS Hapsari, Rani Puspita; Widayati, Retno Indar; Afriliana, Liza; Hadi, Purnomo
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 4 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (424.391 KB)

Abstract

Background: Acne vulgaris is a chronic inflammatory disease in the pilosebaceous follicle of the skin as the result of Propionibacterium acnes colonization. Clindamycin is an antibiotic that is effective against most gram-positive anaerobic bacteria such as the strain of  Propionibacterium sp. Clindamycin in topical form inhibits P. acnes lipase enzyme resulting in the decrease of free fatty acid on the skin surface and the decrease of the Propionibacterium acnes population.  Aim: To know the effect of topical clindamycin gel application on the severity degree of acne vulgaris among female college students of Diponegoro University. Methods: The study has done on 34 female college students of Diponegoro University who were diagnosed with Acne Vulgaris. All of the subjects underwent a face skin examination where the acne lesions were counted before and after the treatment. The treatment given was the application of clindamycin topical gel once a day for four weeks. The counted acne lesions were classified into the severity degree of acne vulgaris by Plewig and Kligman. The study compared the severity degree of acne vulgaris before and after the treatment. Statistical analysis of this study used the Wilcoxon test. Result: The result of pre and post-treatment data showed a significant decrease in the severity degree of acne vulgaris after the treatment application (p=0.000). The decrease of severity degree was marked by the decrease of acne lesion count after having four weeks of treatment. This significant result indicated an effective recovery of acne vulgaris after being given the treatment of topical clindamycin. The antibiotic and anti-inflammation effects of clindamycin were discovered effectively healing the lesions of acne vulgaris, therefore, decreasing its severity. Conclusion: Topical clindamycin can effectively reduce the severity degree of acne vulgaris among female college students of Diponegoro University.
Benefits of Topical Avocado Oil in Improving Skin Moisture: A Study in Atopic Dermatitis Patients Pramitasari, Yuniar Dian; Muslimin, Muslimin; Afriliana, Liza
Medica Hospitalia : Journal of Clinical Medicine Vol. 13 No. 2 (2026): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v13i2.1473

Abstract

BACKGROUND : Atopic dermatitis is a chronic skin condition characterized by recurrent flare-ups that impair skin barrier function and significantly affect patients’ quality of life. One of the key strategies in managing atopic dermatitis is to strengthen and maintain the skin's barrier function while reducing inflammation commonly achieved through the use of moisturizers such as petrolatum. However, petrolatum has several drawbacks, including a thick consistency that makes it difficult to apply, a greasy and shiny appearance, and the potential to cause follicular occlusion. As an alternative, avocado oil offers promising benefits due to its non-comedogenic properties and non-greasy finish. AIM :  To determine the difference in effectiveness between avocado oil and petrolatum in improving skin moisture. METHOD : This study is a single-blind randomized clinical trial using a two-parallel group pre- and post-test design. Samples were selected using consecutive sampling. The treatment was applied to the right and left forearms of patients with non flare-ups atopic dermatitis. RESULT :  The variable of user complaints was statistically significant in the general characteristics, with a p-value of <0.05. The TEWL (Transepidermal Water Loss) score for topical avocado oil showed a significant difference compared to petrolatum, with a p-value of <0.001. CONCLUSION : A greater reduction in TEWL (indicating improved skin moisture) was observed with the application of 100% topical avocado oil in patients with non flare-ups atopic dermatitis, compared to the use of 100% topical petrolatum.
Co-Authors Hapsari, Rani Puspita Muslimin Muslimin Purnomo Hadi Retno Indar Widayati Yuniar Dian Pramitasari