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All Journal Indonesian Journal of Biotechnology INDONESIAN JOURNAL OF PHARMACY BIOEDUKASI Dinamisia: Jurnal Pengabdian Kepada Masyarakat JURNAL PENDIDIKAN TAMBUSAI Advances in Food Science, Sustainable Agriculture and Agroindustrial Engineering (AFSSAAE) Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Pengabdian dan Peningkatan Mutu Masyarakat (JANAYU) Prosiding University Research Colloquium Safari : Jurnal Pengabdian Masyarakat Indonesia International Journal of Health Science and Technology JHeS (Journal of Health Studies) Jurnal Sosial dan Sains Hasil Karya Aisyiyah Untuk Indonesia Baktimu : Jurnal Pengabdian Kepada Masyarakat Jurnal Bioteknologi & Biosains Indonesia (JBBI) Baktimu : Jurnal Pengabdian Kepada Masyarakat Jurnal Bioteknologi & Biosains Indonesia
Annisa Khumaira
Universitas Aisyiyah Yogyakarta
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Journal : BIOEDUKASI

 1 
POTENCY OF ANTICANCER COMPOUNDS FROM THE InaCC LIPI COLLECTION Actinomycetes WERE ANALYZED USING antiSMASH Annisa Khumaira; Tsania Taskia Nabila
BIOEDUKASI Vol 19 No 1 (2021)
Publisher : PROGRAM STUDI PENDIDIKAN BIOLOGI FAKULTAS KEGURUAN DAN ILMU PENDIDIKAN UNIVERSITAS JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/bioedu.v19i1.22747

Abstract

Every year cancer cases have always increased. According to WHO data, in 2020, there were 19.2 million cases of cancer. Cancer treatment is still developing by exploring medicinal compounds that have a minimal risk to healthy cells but can still kill cancer cells. Secondary metabolites from the phylum Actinomycetes are often explored to determine their usefulness, one of which is an anticancer compound. The InaCC project from LIPI has several collections of Actinomycetes that have never been explored, mainly novel species obtained in the 2011-2016 timeframe. The purpose of this study was to analyze the genomic sequences of the InaCC Actinomycetes collection using antiSMASH to determine the potential of the compounds for anticancer. First, the genome sequence data search was carried out through the NCBI gene bank, then analyzed the sequences using antiSMASH 5.0, after searching for the compounds' potential through publication search using the ChEMBL Database and Google Scholar. In the NCBI database, all bacterial phylum Actinomycetes InaCC 2011-2016 have not found any genomic sequence data to use bacteria with the closest relationship for antiSMASH analysis. The closest relatives' analysis results showed that BGC compounds that can have anticancer properties in the bacterial collection of the phylum Actinomycetes InaCC 2011-2016 include terpenes butyrolactol, furans, alkyresorcinol, desferroxamine, and siderophore. These results indicate that the phylum Actinomycetes bacteria could have BGC anticancer compounds and could be developed to treat cancer. The analysis of this research needs to be confirmed again if each bacterium's genomic sequence is complete.
Isolation and Characterization of Local Microorganisms (MOL) of Bamboo Shoots (Dendrocalamus asper) and Its Effect on the Growth of Pakcoy Plants (Brassica rapa L.) Mariatil Kabatia; Annisa Khumaira; Arif Bimantara
BIOEDUKASI Vol 21 No 2 (2023)
Publisher : PROGRAM STUDI PENDIDIKAN BIOLOGI FAKULTAS KEGURUAN DAN ILMU PENDIDIKAN UNIVERSITAS JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/bioedu.v21i2.39430

Abstract

MOL is an organic fertilizer made from fermented natural materials that contain carbohydrates and many macro and micro nutrients. This type of fertilizer also contains microorganisms that its contribute towards role as biofertilizer. One potential organic material for MOL that is easily available is bamboo shoots. Bamboo shoots contain important nutrients which can improve plant growth and development. The purpose of this study was to determine what bacteria are contained in bamboo shoot MOL and to determine its effect on growth in pakcoy plants (Brassica rapa L). This research is an experimental study using RAL (Complete Randomized Design), including: isolation and characterization of bamboo shoot MOL, application of MOL to pakcoy plants (Brassica rapa L) containing bacterial isolates from bamboo shoot MOL. The observed parameters include plant height, root length, number of leaves and wet weight of pakcoy plants followed by statistical analysis using analysis of variance (ANOVA) and characterization results on isolates obtained based on Bergey's Manual of Determinative Bacteriology. From the research results obtained that the prediction of the genus of bacteria contained in bamboo shoots is Lactobacillus, Streptococcus Sp, Saccharococcus, Veillonella sp, Azotobacter, and Rhizobacter which play a role in accelerating decomposition so as to produce the best quality fertilizer and MOL contained in bamboo shoots has a significant effect on the growth of pakcoy (Brassica rapa L). The best result for MOL bamboo shoots that are good for pakcoy plant growth is obtained at a concentration of 150ml / L so that MOL bamboo shoots have the potential for pakcoy plant growth.
Isolation and Characterization of Sugarcane Root (Saccharum sp.) Rhizobacteria and Their Influence on the Growth of Lettuce Plants (Lactuca sativa L.) Rismaningsih, Eka; Khumaira, Annisa; Nugraheni, Ika Afifah
BIOEDUKASI Vol 22 No. 2 (2024)
Publisher : PROGRAM STUDI PENDIDIKAN BIOLOGI FAKULTAS KEGURUAN DAN ILMU PENDIDIKAN UNIVERSITAS JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/bioedu.v22i2.43596

Abstract

Lettuce (Lactuca sativa L.) is a horticultural commodity with good commercial value. Lettuce production is insufficient for consumer needs because of the excessive use of inorganic fertilizers, which reduce soil fertility. This research aims to decide rhizobacteria in the rhizosphere of sugarcane roots and their influence on increasing the growth of lettuce plants. The methods used are observational methods for taking composite soil samples. Macroscopic observations of bacterial colonies include the shape, elevation, edges, and color of the colonies produced. Through gram staining and physiological tests, including catalase, motility, carbohydrate fermentation, and indole tests, performed microscopic character observations. Field tests as PGPR were carried out on lettuce plants with treatment P0, P1, P2 and P3. The parameters observed were plant height, number of leaves, wet weight, dry weight, and root length. Based on the results of the research, the PGPR of sugarcane roots has rhizobacteria such as Corynebacterium sp, Terrabacter, Saccharococcus, Aeromicrobium, Paracoccus, Ancylobacter, Planococcus, and Azotobacter. PGPR affects the growth of lettuce plants, especially on plant height, number of leaves, and root length. Treatment P3 (PGPR 7.5 ml/L) and treatment P1 (2.5 ml/L) obtained the best concentrations, yielding optimal results on all test parameters. Treatments P0 and P2 did not have a significant effect on the growth of lettuce plants.
Formulation, Stability Test and Antibacterial Activity of Banana Leaf Extract Liquid Soap (Musa sp.) against the Growth of Escherichia coli Wahyuningsih, Erpika Ambar; Khumaira, Annisa
BIOEDUKASI Vol 22 No. 3 (2024)
Publisher : PROGRAM STUDI PENDIDIKAN BIOLOGI FAKULTAS KEGURUAN DAN ILMU PENDIDIKAN UNIVERSITAS JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/bioedu.v22i3.47850

Abstract

Liquid soap is an important component in maintaining skin cleanliness. Good liquid soap is soap that contains natural antioxidants because it can protect the body from free radicals and prevent cell damage and is also antibacterial because it can prevent and kill pathogens. One source of easily available phytochemical compounds with antioxidant and antibacterial activity is banana leaves (Musa sp.). The aim of this research was to formulate physically and chemically stable banana leaf extract liquid soap and test the antibacterial effectiveness of banana leaf extract liquid soap with formulations of 0%, 1%, 3%, 5% and 7% against the growth of Escherichia coli. This research was carried out using Completely Randomized Design which included making extracts, phytochemical screening tests, organoleptic tests, hedonic tests, pH tests, homogeneity tests, foam stability tests, and antibacterial tests on Escherichia coli using the diffusion method (paper disc). Then statistical analysis of variance (ANOVA) was carried out to determine the differences in the five formulas. Integrating banana leaf phytochemical compounds into soap formulas produces products that are antioxidant and antibacterial. The best formula is at an extract concentration of 7% because it provides optimal antibacterial test results and meets SNI standards for foam stability.
Co-Authors Adika Pranata Afif Pranaya Jati Afifa, Adinda Afifah Nurul Falih Aini, Zahratun Annaziha, Salma Arif Bimantara Arlia Rasita Ata Rofita Wasiati Baihaqi, Muhammad Azizan Azmani Batubara, Maryam Dinar Mindrati Fardhani Dini Alfaruqi, Hamiyawati Qoimatu Fathah, Rigel Nurul Fuad Gandhi Torizal Hamiyawati Qoimatu Dini Alfaruqi Ika Afifah Nugraheni Inna Armandari Khasana, Nanda Putri Insan Mariatil Kabatia Meivi, Sandrina Miwing Nurul W Muhammad Alfikri Muhammad Arjun Najib Muhammad Arjun Najib Muthi Ikawati Nanda Putri Insan Khasana nita widyaningsih Nosa Septiana Anindita Nurul W, Miwing Rahmawati, Fitri Maulidah Risky Fauzy Hasibuan Rismaningsih, Eka Saharuddin, Erni Sandra Fitriany, Dhea Sari, Windy Adinda Susila, Wisnu Adhi Sutopo Aris Wibowo Tsania Taskia Nabila Tsania Taskia Nabila Viko Aldi Putra Viko Aldi Putra Wahyuni Wulansari Wahyuningsih, Erpika Ambar Wibowo, Sutopo Aris widyaningsih, nita Wisnu Adhi Susila Wiwit Probowati Yogi Ertanto Zintya Sari, Fitria