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Uncontrolled blood sugar tends to increase prevalence of dermatomycosis in diabetic type 2 patients Surja, Sem Samuel; Hermawan, Melyawati; Wijaya, Meiliyana; Pramanta, Pramanta; Yolanda, Hanna
Universa Medicina Vol 37, No 3 (2018)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (729.675 KB) | DOI: 10.18051/UnivMed.2018.v37.188-194

Abstract

Background The prevalence of type 2 diabetes mellitus (DM) is increasing. Diabetic patients have a higher risk of getting dermatomycosis. Dermatomycoses, although a common health problem amongst DM, is often misdiagnosed and consequently undertreated. Studies on the association between dermatomycosis and type 2 diabetes are lacking, especially in Indonesia. Therefore, the aim of this study was to determine the prevalence, etiology, and association of dermatomycosis with diabetic control of type 2 DM. MethodsA cross-sectional study was performed involving 87 subjects with type 2 DM. Demographic and clinical data, including age, sex, and blood glucose level, were collected. If a dermatomycosis lesion was found, a specimen would be taken for identification. Determination of serum glucose level was conducted using Roche c111 analyzer®. Statistical analysis was performed with the chi-square test and Kolmogorov-Smirnov two-independent sample test.ResultsSeventeen (19.55%) subjects had dermatomycosis. The predominant age group affected was 51 - 60 years (42.4%). The number of clinically apparent dermatomycosis was greater in the uncontrolled than in the controlled blood sugar group, but the difference was statistically not significant (p > 0.05). The lesions were mostly found on the nails (74%) and the most common etiology was candida (50%) followed by dermatophyte (25%) and non-dermatophyte molds (25%). ConclusionUncontrolled blood sugar tends to increase the risk of dermatomycosis in type 2 DM patients. Fungal skin infections are common in type-2 DM patients, especially in those with poor glycemic control.
UJI COBA PENGGUNAAN LIMBAH AIR KELAPA TUA SEBAGAI BAHAN DASAR MEDIA ISOLASI Yolanda, Hanna; Mulyana, Yanti
Majalah Kedokteran Bandung Vol 43, No 3
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (618.309 KB)

Abstract

Media pembenihan isolasi yang umumnya digunakan adalah media sintetik yang diimpor dan harganya mahal. Banyak bahan organik yang secara alamiah mengalami pemecahan senyawa organik kompleks menjadi senyawa sederhana oleh mikrob. Berdasarkan pemikiran inilah, peneliti mencoba membuat media isolasi dengan bahan dasar limbah air kelapa tua, sehingga dapat menjadi pertimbangan sebagai media yang lebih ekonomis. Metode penelitian adalah eksperimental laboratorik dengan mengisolasi bakteri uji menggunakan media berbahan dasar air kelapa tua. Media air kelapa tua dikomposisikan menyerupai komposisi agar MacConkey dan lempeng agar darah (LAD). Media standar yang digunakan adalah agar MacConkey dan LAD. Media kontrol yang digunakan adalah media agar 15 g/L dan media agar air kelapa tua. Bakteri yang diuji adalah beberapa spesies Enterobacteriaceae dan kokus gram positif. Variabel yang dinilai adalah gambaran makroskopis dan mikroskopis. Analisis data menggunakan teknik Wilcoxon matched pairs test dan sign test. Hasil penelitian menunjukkan perbedaan tidak bermakna (p>0,05) antara media standar dan media air kelapa tua. Gambaran spesifik dari bakteri uji seperti koloni berwarna merah, gambaran mukoid, dan zona hemolitik tampak serupa antara media standar dan media air kelapa tua. Simpulan penelitian ini adalah air kelapa tua dapat dimanfaatkan sebagai bahan dasar media isolasi Enterobacteriaceae dan kokus gram positif. [MKB. 2011;43(3):117?21].Kata kunci: Agar MacConkey, air kelapa tua, isolasi, lempeng agar darah, media  Using Ripe Coconut Waste-Water as Base for Isolation Media SubstanceThe culture media commonly used for isolation are imported and expensive. Many organic materials are naturally decomposed from complex organic compounds to simple ones by microbes. Based on this principles, this study wants to make isolation media with ripe coconut waste-water as based substance, so it can be considered as economical culture media. The method was laboratoric experimental by isolating tested bacteria with ripe coconut waste-water as based substance. The composition of the media were adjusted with MacConkey agar and blood agar base. Standard media were MacConkey agar and blood agar base. Control media were agar 15 g/L media and ripe coconut waste-water agar media. Tested bacteria were a number species of Enterobacteriaceae and positive gram cocci. The evaluated variables were macroscopic and microscopic images. Data was analized by Wilcoxon matched pairs test and sign test methods. This study did not find a significant differences (p>0.05) between standard media and ripe coconut waste-water media. Specific characteristics of tested bacteria, such as red colonies, mucoid, and hemolitic zone, were similar between standard media and ripe coconut waste-water media. The conclusion is ripe coconut waste-water can be used as base for isolation media substance of Enterobacteriaceae and gram positive cocci. [MKB. 2011;43(3):117?21].Key words: Blood agar base, MacConkey agar, isolation, media, ripe coconut waste-water DOI: http://dx.doi.org/10.15395/mkb.v43n3.56
PENGARUH KONSUMSI DARK CHOCOLATE TERHADAP FUNGSI KONSENTRASI VISUAL MAHASISWA FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS KATOLIK INDONESIA ATMA JAYA Jeremiah Mai Nugraha; Hanna Yolanda; Linda Suryakusuma
Bahasa Indonesia Vol 18 No 1 (2019): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v18i1.2203

Abstract

Introduction: Cognitive function is essential for medical students to support learning at the university. One part of cognitive function that is very important in student learning is visual concentration. Visual concentration is the process of maintaining a concentration of thought on a visual object by putting aside other things that are not related. Concentration can be increased in several ways, one of which is to consume nutritious foods that contain flavonoids such as dark chocolate. The purpose of this study was to determine the effect of dark chocolate consumption on visual concentration of cognitive function in Atma Jaya’s medical students.Methods: This was an experimental study and the data were tested using t-paired statistical test. The research was conducted from March to April 2019 at Atma Jaya Catholic University of Indonesia School of Medicine and Health Sciences, Jakarta. The data ovtained from Stroop Test before and after intervention of dark chocolate. A total of 51 respondents were selected according to the research criteria.Results: As many as 48 people (94.1%) experinced an increase in the Stroop Test Score, a person (2%) did not experience a change in the Stroop Test Score, and two people (3.9%) experinced a decrease in the Stroop Test Score. The result of statistical test show significant results (p<0.01). The average score before the intervenion was obtained at 77.02±10.42 and the average score after the intervention was obtained at 77.02±11.81 (Δ= +12.26).Conclusion: There is an effect of dark chocolate consumption on visual concentration of cognitive function in Atma Jaya’s medical student
HUBUNGAN KEBERSIHAN DIRI DENGAN KEJADIAN INFEKSI ENTEROBIUS VERMICULARIS PADA ANAK USIA 2 – 10 TAHUN DI RUMAH SUSUN PENJARINGAN Natasha Gabby Ratimanjari; Hanna Yolanda
Bahasa Indonesia Vol 18 No 2 (2019): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v18i2.2224

Abstract

Introduction: Development of medicine in Indonesia goes along with the diseases that emerged from lifestyle. Prevention can be done by implementing clean and healthy life protection (PHBS). One of the diseases that can occur due to lack of PHBS is worm infection. One of the worms that often infects children is Enterobius vermicularis. This study was conducted to assess the relationship between personal hygiene and E. vermicularis infection. Methods: This is a cross-sectional study with data taken from 110 children (2-10 years) with parents / guardians at Rumah Susun Penjaringan, North Jakarta. The independent variable of this study is personal hygiene and the dependent variable is E. vermicularis infection in children that uses data from questionnaires and lab exams. Results: The study was attended by 110 respondents. It is found that more than 80% of respondents wash their hands with soap before eating, wash their hands with soap after using the toilet, do not scratch the anus at night, routinely clip nails at least once a week, and use footwear while playing outdoors. More than 90% of respondents change their bed sheets regularly and took a bath twice a day. All respondents bathed using clean water and soap. More than 70% of respondents do not bite their nails, wash their hands after going to play, and consume anthelmintics. More than 50% of respondents do not wear other people's underwear. The results of the laboratory study found no E. vermicularis eggs. Conclusion: There is no infection of E. vermicularis in children age 2 – 10 at Rumah Susun Penjaringan
Nepenthes rafflesiana pitcher liquid has antifungal activity against Candida spp. Hanna Yolanda; Ingrid M. Makahinda; Maureen Aprilia; Nikki Sanjaya; Harry Gunawan; Rita Dewi
Universa Medicina Vol. 33 No. 2 (2014)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2014.v33.83-90

Abstract

BACKGROUNDTo develop new effective antifungals, it is essential to search for antifungal compounds from plants such as Nepenthes spp., which have their greatest diversity in Indonesia. Since chitin-induced liquid (CIL) from Nepenthes khasiana pitchers has antifungal activity, due to their naphthoquinone content, this study aimed to evaluate antifungal activity of Nepenthes rafflesiana pitcher liquids on Candida spp.METHODSCollected pitcher liquids were of 3 types: non-induced liquid (NIL), prey-induced liquid (PIL), and chitin-induced liquid (CIL). Non-induced liquid (NIL) was collected from fresh naturally opened pitchers, PIL from opened pitchers after 3 hours of induction with Zophobas morio larvae, and CIL from closed pitchers after 5 days of chitin solution injection. The antifungal activity of the liquids against C. albicans, C. glabrata, C. krusei, and C. tropicalis were detected by disc diffusion and macrodilution methods.RESULTSInhibition zone diameters of NIL, PIL, and CIL against C. albicans were 35.00 (35.00 – 39.33) mm, 26.33 (23.00 – 40.00) mm, and 30.00 ( 28.00 – 32.00) mm, respectively, while for C. glabrata the zone diameters were 22.22 ± 3.66 mm, 29.89 ± 2.79 mm, and 28.89 ± 1.17 mm, respectively. No inhibition zones were found for NIL, PIL, and CIL against C. krusei and C. tropicalis. At concentrations of 80%, almost all samples showed visually apparent inhibition of fungal growth.CONCLUSIONThe pitcher liquid of N. rafflesiana has antifungal properties, presumably due to the presence of many potentially active substances, such as naphthoquinones, as has been proven in other studies.
Hexane neem leaf extract more potent than ethanol extract against Aspergillus flavus Jenny Hidayat; Ay Ly Margaret; Hanna Yolanda; Lies K. Wibisono
Universa Medicina Vol. 33 No. 3 (2014)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2014.v33.171-178

Abstract

BACKGROUND Aspergillus flavus is one of the causes of aspergillosis, with a high virulence and resistance to standard antifungals, resulting in a high mortality rate. Medicinal plants are increasingly used as they are relatively safer with minimal side effects. Previously we found that the ethanol extract of neem (Azadirachta indica A Juss) leaves inhibits A. flavus growth in vitro. However, most chemical compounds with antifungal effect are nonpolar. The purpose of this research was to compare the antifungal effect of neem leaves extracted in a nonpolar solvent to that of leaves extracted in a polar solvent. METHODS An in vitro experimental research was conducted between October 2013 and January 2014. Neem leaves were extracted in ethanol or hexane at various concentrations. A macrodilution test with 48-hour incubation time was done in triplicate on 8 groups of samples. These comprised the neem leaf ethanol extract (NLEE) at 0.5, 1.0, and 2.0 g/dL, neem leaf hexane extract (NLHE) at 0.5, 1.0, and 2.0 g/dL, positive control, and negative control groups. Fungal growth was detected on Sabouroud dextrose agar. Statistical analysis used Chi square and Fisher’s exact test. RESULTS NLHE had a higher, but statistically non-significant, inhibitory effect on A. flavus than NLEE (p=0.996). At higher concentrations, the antifungal effect of NLHE is better than that of NLEE. CONCLUSION There is no significant difference in in-vitro inhibitory effectivity on A. flavus of neem leaves between extracts in polar and nonpolar solvents.
Antifungal activity of neem leaf ethanol extract on Aspergillus flavus Ayly Margaret; Hanna Yolanda; Wibisono Lies K
Universa Medicina Vol. 32 No. 2 (2013)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2013.v32.80-85

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BACKGROUNDAspergillosis is an infectious disease due to inhalation of Aspergillus spores.Drug resistance to aspergillosis has been reported since 14 years ago. Therefore,alternative treatment using herbals began to attract the attention of the medicalprofession and the community, because herbals are relatively safe and haveminimal side effects. Neem (Azadirachta indica) is an herb with broad spectrumbiological activity, but studies on the antifungal activity of neem leaves arelacking. The objective of this study was to evaluate the activity of neem leaveson Aspergillus flavus (A. flavus).METHODSThis was a laboratory experimental study using A. flavus samples obtained frombronchial washing specimens of inpatients. Neem leaf extract in ethanol (NLE)was prepared in various concentrations. Aspergillus. flavus antifungal activityof NLE were assessed by disc diffusion (using NLE at 1.0; 0.75; 0.50; 0.25 g/dL)and macrodilution (using NLE at 1.0; 0.75; 0.5; 0.25; 0.125 g/dL). Ketoconazole0.1 g/dL was used as antifungal positive control. Disc diffusion and macrodilutionwere conducted using Sabouraud dextrose agar and broth, to measure inhibitionzone diameter and minimal inhibitory concentration (MIC), respectively. Statisticalanalysis was performed using Mann-Whitney test from SPSS 15.RESULTSThere were significant differences in inhibition zone diameter (p = 0.034) betweenA. flavus samples exposed to NLE (1 g/dL) and the control group exposed toketoconazole (0.1 g/dL). The MIC of NLE against A. flavus was 0.5 g/dL.CONCLUSIONSNeem leaf ethanol extract has antifungal activity against A.flavus in vitro.
BAHASA BATAK TOBA SEBAGAI PEMBENTUK KARAKTER DAN PENUNJANG PEMBELAJARAN KURIKULUM 2013 DI SD N 173652 KABUPATEN TOBA Yolanda, Hanna; Sinaga, Warisman
Kompetensi : Jurnal Pendidikan dan Humaniora Fakultas Keguruan dan Ilmu Pendidikan UNIBA Vol 16 No 1 (2023): Kompetensi
Publisher : Fakultas Keguruan dan Ilmu Pendidikan, Universitas Balikpapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36277/kompetensi.v16i1.96

Abstract

Karya ilmiah ini memiliki judul Signifikansi Bahasa Batak sebagai Faktor Kunci dalam Membentuk Karakter dan Mendukung Pembelajaran dalam Kurikulum 2013 di Sekolah Dasar Kabupaten Toba. Penelitian Ini memiliki tujuan agar dapat mengetahui Bagaimana Signifikansi Bahasa Batak sebagai Faktor Kunci dalam Membentuk Karakter dan Mendukung Pembelajaran dalam Kurikulum 2013 di Sekolah Dasar Kabupaten Toba. Karya ilmiah ini menggunakan Teori yang digunakan adalah teori kognitivisme dan teori konstruktivisme. Metode yang digunakan metode kualitatif. Hasil yang telah didapat dalam penelitian ini merupakan : (1) Terdapat 12 karakter yang memiliki peran penting dalam pembentukan karakter siswa SD 173652 desa Tanjung Pasir, (2) Dalam penelitian ini ditemukan 2 peran bahasa Batak Toba sebagai penunjang pembelajaran kurikulum 2013 yang gunakan di SD 173652 Desa Tanjung Pasir, (3) Dalam penelitian ini ditemukan 2 faktor yang mempengaruhi bahasa Batak Toba sehingga memiliki peran dalam pembentukan karakter dan sebagai penunjang pembelajaran Ke 2 faktor itu adalah faktor internal dan faktor eksternal. Faktor eksternal terbagi menjadi 3 yaitu faktor  internal psikologis, faktor internal kebiasaan, faktor internal cita-cita  dan faktor eksternal juga terbagi menjadi 3 yaitu faktor keluarga, faktor lingkungan sekitar dan faktor lingkungan sekolah. Seluruh faktor di atas berpengaruh dalam memberikan peran pada bahasa Batak Toba sebagai pembentuk karakter dan sebagai penunjang pembelajaran kurikulum 2013 di SD 173652 Desa Tanjung Pasir, Kecamatan Parmaksian, Kabupaten Toba.
PENGENALAN PROGRAM STUDI FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK INDONESIA ATMA JAYA MELALUI WORKSHOP PEMBUATAN APUSAN TINJA DAN DEMO PREPARAT PARASITOLOGI Surja, Sem Samuel; Olivia, Vera; Margareta, Revi; Yolanda, Hanna; Joprang, Freggy Spicano; Kaisar, Maria Mardalena Martini; Wijaya, Meiliyana
Mitramas: Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol. 3 No. 2 (2025)
Publisher : Universitas Katolik Indonesia Atma Jaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/mitramas.v3i2.6505

Abstract

Program Studi Kedokteran, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Katolik Indonesia Atma Jaya (FKIK UAJ) menyelenggarakan kegiatan edukasi berupa workshop pembuatan apusan tinja dengan pewarnaan lugol dan demo preparat parasitologi. Kegiatan dirancang untuk memberikan gambaran mengenai pembelajaran dalam program studi kedokteran terutama saat berada di tahap preklinik. Ilmu parasitologi merupakan salah satu ilmu yang wajib dikuasai oleh lulusan kedokteran. Hal tersebut relevan karena sebagai salah satu negara beriklim tropis, penyebaran penyakit infeksi akibat parasit masih banyak ditemukan di Indonesia. Kegiatan edukasi dilakukan di laboratorium FKIK UAJ diikuti oleh siswa/i SMA Pahoa Gading Serpong. Evaluasi keberhasilan kegiatan dilakukan dengan membandingkan nilai pre-test dan post-test menggunakan aplikasi Quizizz. Hasil perbandingan nilai pre-test dan post-test terdapat kenaikan sebesar 27,7%. Hal tersebut menunjukkan adanya peningkatan pengetahuan umum siswa/i di bidang parasitologi. Kegiatan yang telah dilakukan memberikan dampak yang baik terhadap program pengenalan kampus FKIK UAJ dan meningkatkan pengetahuan siswa/i terhadap bidang ilmu kedokteran khususnya parasitologi. Sehingga kegiatan serupa dapat dilakukan secara berkesinambungan.
PENGENALAN PROGRAM STUDI FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK INDONESIA ATMA JAYA MELALUI WORKSHOP PEMBUATAN APUSAN TINJA DAN DEMO PREPARAT PARASITOLOGI Surja, Sem Samuel; Olivia, Vera; Margareta, Revi; Yolanda, Hanna; Joprang, Freggy Spicano; Kaisar, Maria Mardalena Martini; Wijaya, Meiliyana
Mitramas: Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol. 3 No. 2 (2025)
Publisher : Universitas Katolik Indonesia Atma Jaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/mitramas.v3i2.6505

Abstract

Program Studi Kedokteran, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Katolik Indonesia Atma Jaya (FKIK UAJ) menyelenggarakan kegiatan edukasi berupa workshop pembuatan apusan tinja dengan pewarnaan lugol dan demo preparat parasitologi. Kegiatan dirancang untuk memberikan gambaran mengenai pembelajaran dalam program studi kedokteran terutama saat berada di tahap preklinik. Ilmu parasitologi merupakan salah satu ilmu yang wajib dikuasai oleh lulusan kedokteran. Hal tersebut relevan karena sebagai salah satu negara beriklim tropis, penyebaran penyakit infeksi akibat parasit masih banyak ditemukan di Indonesia. Kegiatan edukasi dilakukan di laboratorium FKIK UAJ diikuti oleh siswa/i SMA Pahoa Gading Serpong. Evaluasi keberhasilan kegiatan dilakukan dengan membandingkan nilai pre-test dan post-test menggunakan aplikasi Quizizz. Hasil perbandingan nilai pre-test dan post-test terdapat kenaikan sebesar 27,7%. Hal tersebut menunjukkan adanya peningkatan pengetahuan umum siswa/i di bidang parasitologi. Kegiatan yang telah dilakukan memberikan dampak yang baik terhadap program pengenalan kampus FKIK UAJ dan meningkatkan pengetahuan siswa/i terhadap bidang ilmu kedokteran khususnya parasitologi. Sehingga kegiatan serupa dapat dilakukan secara berkesinambungan.