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All Journal Narra J Jurnal Indonesia Sosial Sains Journal of Medicine and Health
Salim, Stephanie
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Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Energy Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Physics Public Health Social Sciences

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Correlation of skin moisture and serum urea level with dermatology life quality index in patients with chronic kidney disease on hemodialysis: A cross-sectional study Dalimunthe, Dina A.; Hazlianda, Cut P.; Lubis, Flora M.; Sinaga, Riana M.; Salim, Stephanie
Narra J Vol. 4 No. 3 (2024): December 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i3.967

Abstract

Chronic kidney disease (CKD) is a global health concern, with a 10% global prevalence. Its prevalence may further increase in the coming decades, thereby increasing the risk of uremic xerosis. Approximately 50–90% of patients with CKD have xerosis, leading to pruritus that affects their quality of life due to sleep disturbances, anxiety, and depression. However, the exact mechanisms underlying xerosis in CKD remain unknown. The aim of this study was to assess the correlation of serum urea levels and skin moisture with quality of life in patients with CKD. This cross-sectional study was conducted at the Universitas Sumatera Utara Hospital from March to December 2023. Patients with CKD aged ≥18 years who were undergoing hemodialysis for at least 3 months were included in this study. A translated Dermatology Life Quality Index (DLQI) questionnaire was employed to assess the patient’s quality of life. Serum urea levels and skin moisture were determined using venous blood and the Skin Moisture Checker MY-808S tool, respectively. In total, 67 patients with CKD, including 61.2% males and 32.8% individuals aged >60 years, were enrolled in this study. The mean age was 52.73±13.08 years. The mean serum urea levels, skin moisture, and DLQI scores were 154.08±49.10 mg/dL, 36.22±2.34%, and 4.67±3.98, respectively. No difference in DLQI scores was observed between normal and high serum urea levels or between dry and normal skin moisture levels (p=0.156 and p=0.804, respectively). Spearman’s correlation analysis revealed no correlation between serum urea levels and average skin moisture with DLQI (p=0.600 and p=0.353, respectively), indicating that multiple factors contribute to the dermatological quality of life in patients with CKD. Notably, DLQI in patients with CKD can be simultaneously affected by multiple factors, such as diverse sociodemographic backgrounds, coping mechanisms, and the impact of symptoms associated with CKD, other than serum urea levels and average skin moisture. Therefore, adopting a multifactorial and individualized approach is crucial to improving the DLQI scores of patients with CKD.
Studi Kasus: Optimalisasi Regenerasi Kulit Pasca Prosdeur Estetik dengan Perawatan Kulit Dermo-kosmetik Setiawan, Stanley; Darmawan, Hari; Putranto, Samuel S; Linata, Angela M; Salim, Stephanie; Nobel, Shelly
Journal of Medicine and Health Vol 6 No 2 (2024)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v6i2.8269

Abstract

The use of ecobiology-based dermocosmetics containing Antalgicine™ can expedite the optimization of skin regeneration post-aesthetic procedures. The aim of this case study assess the clinical benefit of Antalgicine™ post-aesthetic procedures. Six patients were recruited into this case study which utilizes subjective and objective measurements. Antalgicine™ was applied using a split-face study method. Subjective evaluation is graded by patients using a 1-5 Likert scale, along with objective evaluation, was performed by a blinded dermatologist. Results showed an objective reduction in post-aesthetic procedure on day 7, namely 40% for microneedling, 32% for fractional radiofrequency, and 29% for picosecond laser, as well as subjective reductions in every post-aesthetic procedure sensation, specifically pain, pruritus, tightness, and burning sensation at 67%, 75%, 67%, 33% for microneedling, 71%, 67%, 67%, 50% for fractional radiofrequency, and 67%, 75%, 78%, 60% for picosecond laser, respectively. As a conclusion, Antalgicine™ can reduce post-aesthetic procedure effects for optimizing skin regeneration.
The Human Rights Aspects Involved in the Implementation of Pregnancy Programs Through Non-Natural Methods Salim, Stephanie; Noor, Tauchid; Adriano, Adriano
Jurnal Indonesia Sosial Sains Vol. 6 No. 3 (2025): Jurnal Indonesia Sosial Sains
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jiss.v6i3.1663

Abstract

This research aims to analyze the human rights aspects involved in the implementation of pregnancy programs beyond natural methods. The focus is on understanding the legal and ethical implications of assisted reproductive technologies (ART), such as in vitro fertilization (IVF), sperm and egg donation, and surrogacy. These technologies offer solutions for couples facing infertility but raise significant human rights and ethical issues, particularly regarding patient autonomy and the legal framework surrounding their use in Indonesia. The research methodology used in this thesis is normative juridical and the research approach utilizes a statutory, conceptual and comparative approach to examine national and international legal instruments, including the Indonesian Health Law and human rights conventions, to evaluate the extent to which they protect the rights of individuals undergoing ART procedures. The study found that while existing laws provide some level of protection, there are gaps and inconsistencies that may hinder the effective realization of reproductive rights. Recommendations include improving legal clarity and regulatory oversight, raising public awareness on reproductive rights, and ensuring that ART services are accessible and ethically implemented. By addressing these issues, this thesis aims to contribute to the development of a stronger legal framework that supports individual reproductive autonomy and upholds human rights in the context of assisted reproduction.
Co-Authors Adriano Adriano, Adriano Dalimunthe, Dina A. Hari Darmawan Hazlianda, Cut P. Linata, Angela M Lubis, Flora M. Nobel, Shelly Noor, Tauchid Putranto, Samuel S Setiawan, Stanley Sinaga, Riana M.