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All Journal Public Health of Indonesia Journal of Pharmaceutical and Sciences. Svāsthya: Trends in General Medicine and Public Health
Umar, Tungki Pratama
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Active tuberculosis identification based on workers environmental sanitation during the COVID-19 pandemic Irfani, Tri Hari; Fitri, Agita Diora; Roflin, Eddy; Siburian, Reynold; Umar, Tungki Pratama
Public Health of Indonesia Vol. 7 No. 1 (2021): January - March
Publisher : YCAB Publisher & IAKMI SULTRA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v7i1.397

Abstract

Background: Coronavirus Disease 2019 (COVID-19) is a pandemic that may complicate the active detection of Tuberculosis (TB) and increase the mortality rate. This pushes for more effective and efficient case finding to mitigate the possible growing number of TB mortality.Objective: The purpose of this research was to identify TB among workers and to analyze the correlation between human, environmental, behavioral, and economic factors with TB findings among workers during the COVID-19 period.Methods: This research employed a case-control method conducted from January to December 2020. In total, 120 employees were included in this research. The employees were divided into two groups, sixty workers were involved in the TB case group, and another sixty workers were in the control group. We reported TB patients from several Public Health Center (Puskesmas) in each regency of South Sumatera, Indonesia. Sputum testing was performed by the rapid molecular tests (GeneXpert) and Ziehl-Neelsen to confirm the diagnosis of TB infection. We performed a Chi-square analysis to analyze factors that can influence TB cases.Results: In comparison to the control group, we found the association of age, body mass index, occupation, and sun exposure to the incidence of active TB cases (p<0.05).Conclusion: Since statistically significant differences between the two groups have been identified, the incidence of TB in workers might be affected by age, occupation, BMI, and exposure to sunlight. Associated significant variables can be integrated into the TB control program for better case-finding practice to recognize concealed burdens of TB that are overlooked due to COVID-19. This research was funded by Sainteks Sriwijaya University 2020.
Hubungan human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) dengan kejadian penyakit kardiovaskular: konsistenkah bukti yang ada? Fitriani, Indah; Dharmasaputra, Alan; Marshella, Sally; Rosiana, Safira; Pramesuari, Florentina Dewi; Umar, Tungki Pratama
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 4 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i4.546

Abstract

Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS) pose ongoing global health challenges. This literature review evaluates the relationship between HIV infection and increased cardiovascular diseases, outlining findings from sixteen observational studies. Key findings involve an elevated risk of hypertension, coronary artery disease, sudden cardiac death, and cardiovascular risk factors among HIV patients. Additionally, antiretroviral therapy (ART) side effects are highlighted, including specific impacts of certain drugs. The gender of HIV/AIDS patients also plays a role in cardiovascular risk profiles. The study details the pathophysiological mechanisms, such as immune activation and inflammation, involved in the heightened cardiovascular risk in individuals with HIV/AIDS. This study underscores the importance of a comprehensive understanding of cardiovascular health impacts on the HIV/AIDS population to guide informed therapeutic choices for preventing cardiovascular status deterioration.  
Mpox, HIV infection, and genital skin disease: triple burden, threats and challenges from an epidemiological perspective Adnyana, I Made Dwi Mertha; Eljatin, Dwinka Syafira; Maulana, Sidik; Ibrahim, Kusman; Umar, Tungki Pratama; Armini, Luh Nik; Cruz, Zito Viegas da
Svāsthya: Trends in General Medicine and Public Health Vol. 1 No. 1 (2024): July 2024
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v1i1.1

Abstract

The expansion and transformation of Mpox (MPX) disease alongside HIV and genital skin diseases has led to an increase in global morbidity and mortality in a relatively brief period. These diseases have a similar transmission pathway through sexual intercourse (mainly MSM/men-sex with males). This review aims to provide a concise, evidence-based overview of MPX, HIV, and genital skin disease coinfections, and to identify epidemiological threats and challenges. Our investigations revealed that from January 2022 to July 2023, there was a significant increase in the number of MPX cases, which reached a total of 88,600, resulting in 152 deaths across 113 countries. There have been case reports of triple-burden disease in six different areas of the world, with at least 52% of reported cases occurring in men who have had sexual activity with other men, 84.1% of whom do not use condoms and do not take pre-exposure prophylaxis (PrEP). In addition, the highest number of deaths due to co-infection with MPX, HIV infection, and genital skin diseases occurred in vulnerable groups (LGBTQIA2S+), especially in men who had sex with men, up to 90.9%, and experienced an increase in the frequency of triple burden diseases to 104.9%. From an epidemiological standpoint, this condition generates several threats and challenges, including an increasing burden of infectious diseases, an increase in immunocompromised populations, an increase in overlapping risk factors, diagnostic difficulties, an increase in interactions and comorbidities, and relatively complex treatment challenges. To suppress these outbreaks and pandemics, comprehensive control and prevention should be proposed collaboratively, including collaboration with the education sector to conduct better research and investigation using one health in complex settings. Epidemiological modeling can be used in the future to accelerate the control of these diseases.
Co-Authors Adnyana , I Made Dwi Mertha Agita Diora Fitri Cruz, Zito Viegas da Dharmasaputra, Alan Dwinka Syafira Eljatin Eddy Roflin Indah Fitriani Kusman Ibrahim Luh Nik Armini Marshella, Sally Maulana, Sidik Pramesuari, Florentina Dewi Rosiana, Safira Siburian, Reynold Tri Hari Irfani, Tri Hari