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All Journal Biomedical Journal of Indonesia Jurnal Pengabdian Masyarakat: Humanity and Medicine
Muthia, Putri
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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MRNA NFATC1 EXPRESSION IN GENU OSTEOARTHRITIS WITH EFFUSION Reagan, Muhammad; Hermansyah, Hermansyah; Hidayat, Rachmat; Darma, Surya; Muthia, Putri
Biomedical Journal of Indonesia Vol 6, No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v6i2.10418

Abstract

Based on a study conducted by the WHO Global Burden of Disease in 2010 stated, OA ranks 11th, the cause of disability in the world, and ranks 6th in East Asia and the Asia-Pacific countries, ranked 10th in North America, ranked 7th in Eastern Europe , and ranked 13th in Western Europe. Pathogenesis of osteoarthritis (OA) as degenerative joint disease that was once thought caused by a mechanical process. The prevalence, etiology, pathogenesis and progression of OA are still not understood until now, mainly because of the many influencing factors. This type of research is a analytic study. It was conducted in Rheumatology Polyclinic Dr. Mohammad Hoesin Palembang from February to December 2019. Affordable research population is all genu osteoarthritis sufferers with effusion who go to Dr. RSUP Mohammad Hoesin Palembang as 80 samples. Comparison of NFATC1 mRNA levels in genu osteoarthritis patients with effusion shows that there is no difference in gender and history of diabetes, whereas hypertension history and degree of osteoarthritis based on Lawrence Kalgren shows significantly different expression of NFATC1 mRNA. Age with NFATC1 mRNA expression showed no significant correlation, in contrast to BMI, Stroke Test and joint effusion volume showed a weak significant correlation, even though the direction of the correlation was negative on Stroke Test and joint effusion volume.
Faktor risiko dan gejala osteoporosis pada komunitas dewasa di Desa Ibul Besar Pemulutan Ogan Ilir Sumatera Selatan Umi Partan, Radiyati; Reagan, Muhammad; Hermansyah, Hermansyah; Darma, Surya; Muthia, Putri; Mediarty, Mediarty; Indrajaya, Taufik; Kurniati, Nova; Riviati, Nur; Yuniza, Yuniza
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 2 No 3 (2021): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V2I3.68

Abstract

. Osteoporosis is a worldwide health issue. The microarchitecture of the bone is deteriorating, which increases the risk of fracture and disability. As the Indonesian people's life expectancy increases, the incidence of osteoporosis rises, making it more difficult to manage. This community service is carried out as a form of preventive treatment in the adult community in the village of Ibul Besar III Pemulutan Ogan Ilir, South Sumatra, which is one of Sriwijaya University's guided villages, with counseling methods to increase knowledge and health checks for early detection of osteoporosis, as well as calcium supplementation. There were 81 participants in this activity, with numerous dominant risk factors for osteoporosis identified, including female gender, menopausal state, and age above 50. Musculoskeletal symptoms, such as pain in the waist and back, which can be a consequence of osteoporosis, are more common than non-musculoskeletal symptoms.
Manifestasi klinis dan derajat aktivitas penyakit pada penyandang Lupus Eritematosus Sitemik di Rumah Sakit Dr. Mohammad Hoesin Palembang Partan, Radiyati Umi; Hermansyah, Hermansyah; Darma, Surya; Reagan, Muhammad; Muthia, Putri; Salim, Eddy Mart; Kriswiastiny, Rina; Kurniati, Nova; Yuniza, Yuniza; Silitonga, Aira Priamas
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 5 No 1 (2024): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V5I1.110

Abstract

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that can affect various organs. Clinical manifestations vary from mild to severe depending on the organs involved. Manifestations of SLE in the kidney known as lupus nephritis can occur in 60% of the SLE population and are more common in Asian, Hispanic, Native American, and Black populations, especially in women of childbearing age, involvement of other organs such as neurology is referred to as neuropsychiatric lupus, as well as other organs can manifest such as mucocutaneous lupus, arthritis, pericarditis and other organs. This community service is carried out as a form of preventive treatment with counseling methods to increase knowledge and health checks for early detection of SLE, as well as promotive efforts for the SLE community in the disease polyclinic at Dr. Mohammad Hoesin Palembang, South Sumatra which is one of the teaching hospitals of the Faculty of Medicine, Sriwijaya University. This activity was attended by 35 people with SLE with several risk facts such as female gender and middle adulthood which is quite common, and some of the systemic clinical manifestations experienced are almost fatigue and fever, for musculoskeletal manifestations the most commonly experienced is arthritis, while the most common manifestations of other organs are mucocutaneous disorders. Keywords: Lupus, Autoimmune, Disease Activity
Co-Authors Eddy Mart Salim, Eddy Mart Hermansyah Hermansyah Indrajaya, Taufik Kriswiastiny, Rina kurniati, nova Mediarty, Mediarty Muhammad Reagan Nur Riviati, Nur RACHMAT HIDAYAT Radiyati Umi Partan, Radiyati Umi Silitonga, Aira Priamas Surya Darma Umi Partan, Radiyati Yuniza, Yuniza