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All Journal IJCR (Indonesian Journal of Chemical Research)
Utami, Maisari
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Materials Science & Nanotechnology

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IDENTIFIKASI 11-NOR-Δ 9 -TETRAHYDROCANNABINOL-9-CARBOXYLIC ACID (THC-COOH) DALAM SAMPEL URIN MENGGUNAKAN INSTRUMEN GAS CHROMATOGRAPHY-MASS SPECTROMETRY (GC-MS) Utami, Maisari; Abdushshobir, Muhammad Fadhil; Tanti, Tanti
INDONESIAN JOURNAL OF CHEMICAL RESEARCH Vol. 9 No. 2 (2024): Volume 9, ISSUE 2,2024
Publisher : Chemistry Department, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/ijcr.vol9.iss2.art5

Abstract

“Narkoba” is known as an narcotics, psychotropics, and other addictive substances. Drugs are substances that can affect brain function and often cause dependence. One type of drug that is common in Indonesia is marijuana. Marijuana is a psychotropic that contains tetrahydrocannabinol (THC). When THC enters the human body, it will undergo a metabolic process and produce metabolites in the form of 11-nor-δ 9 -tetrahydrocannabinol-9-carboxylic acid (THC-COOH) which are then excreted in the urine. Urine identification can be used to prove someone's use of marijuana. Identification is carried out using urine from the National Narcotics Agency's Narcotics Laboratory Center to confirm the presence of THC-COOH using a Gas Chromatography-Mass Spectrometer (GC-MS). Urine identification is carried out with a preliminary rapid test and a confirmation test using a GC-MS instrument. The identification results showed that the urine was positive for THC-COOH.
IDENTIFICATION OF 3,4-METHYLENEDIOXYMETHAMPHETAMINE (MDMA) IN URINE SAMPLES USING GAS CHROMATOGRAPHY-MASS SPECTROMETRY (GC-MS) INSTRUMENT Utami, Maisari; Tanti; Meitasari, Eryani Ayu
INDONESIAN JOURNAL OF CHEMICAL RESEARCH Vol. 9 No. 2 (2024): Volume 9, ISSUE 2,2024
Publisher : Chemistry Department, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/ijcr.vol9.iss2.art10

Abstract

Drugs, which is an abbreviation for narcotics, psychotropics and other addictive substances (NAPZA), can cause addiction and have negative impacts on the physical, psychological and social health of users. Although drugs can be used in medical treatment to relieve pain, they can also cause dangerous side effects such as stupor. One example of a drug is ecstasy (MDMA), which can cause feelings of excessive euphoria, but is very dangerous because it can cause hyperthermia, seizures, muscle damage, and disorders of the central nervous system. Drug use, including ecstasy, is very risky and can lead to death, as well as having detrimental social impacts. This study focuses on the identification and analysis of the chemical composition of a tablet suspected to contain illegal substances using Gas Chromatography-Mass Spectrometry (GC-MS). Based on the research results, it shows that the presence of 3,4-methylenedioxymethamphetamine (MDMA) with a similarity index of 94.65%. Additionally, caffeine was also detected in the sample with a similarity index of 96.2%. These findings are crucial for forensic investigations, providing reliable data for law enforcement in the identification of illicit drugs.
Co-Authors Abdushshobir, Muhammad Fadhil Meitasari, Eryani Ayu Ramadani, Randy Samsunar, Sigit Tanti Tanti Tanti