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Therapeutic Effects of Patchouli (Pogostemon cablin) Essential Oil in Relieving Eczema Symptoms in Infants and Toddlers: A Literature Review Deliana, Fitri; Illian, Didi Nurhadi; Nadirah, Siti; Sari, Fadia; Khairan, Khairan
Journal of Patchouli and Essential Oil Products JOURNAL OF PACTHOULI AND ESSENTIAL OIL PRODUCT : VOLUME 2, ISSUE 1 (JUNE 2023)
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jpeop.v2i1.32073

Abstract

This literature review aims to investigate and analyze the therapeutic effect of Patchouli essential oil (Pogostemon cablin) in alleviating eczema symptoms in infants and young children. Eczema is a common skin condition characterized by inflammation, itching, and redness that can significantly affect the quality of life of affected children and their families. Conventional treatments often use topical corticosteroids, which can have potential side effects. This review systematically examines relevant studies, articles, and research from reputable databases, focusing on the use of patchouli essential oil as an alternative therapeutic approach to treat eczema symptoms in the pediatric population. Several aspects are considered, including the chemical composition of patchouli essential oil, its potential mechanisms of action, and its reported efficacy in reducing inflammation and relieving itching associated with eczema. The results of the literature review suggest that patchouli essential oil possesses anti-inflammatory, antimicrobial, and antioxidant properties that may contribute to its therapeutic effect in the treatment of eczema. Several studies have reported positive results, including a reduction in erythema, itching, and overall severity of eczema symptoms in infants and young children. However, the literature also has some limitations, such as the lack of standardized protocols, varying study designs, and limited long-term follow-up data. Overall, this literature review provides valuable insights into the therapeutic effects of patchouli essential oil in alleviating eczema symptoms in infants and young children. Further well-designed studies are needed to determine the optimal dosage, formulation, and long-term safety profile. The results of this review contribute to the growing body of knowledge on alternative treatments for pediatric eczema and provide a foundation for future research and clinical applications in this area.
Utilization of Spent Arabica Coffee Grounds as Raw Material for Activated Charcoal in Liquid Bath Soap Formulation Maysarah, Hilda; Desiyana, Lydia Septa; Nurzuhra, Siti; Illian, Didi Nurhadi
Pharmaceutical Sciences and Research Vol. 10, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Arabica coffee (Coffea arabica) is one of the most popular coffees among Acehnese, an ethnic group from Aceh, Indonesia. The amount of coffee consumed is directly proportional to the amount of coffee waste produced. Spent coffee grounds are the residue obtained during the brewing process. Spent coffee grounds can be utilized by converting them into active charcoal adsorbents. This study aimed to produce activated charcoal from spent arabica coffee grounds (SACG), to utilize it as an active ingredient in the liquid bath soap formulations, and to determine the best formula. The characterization of activated charcoal was conducted and compared to the Indonesian National Standard (SNI). The liquid bath soap contains activated charcoal from SACG was divided into five formulas with various concentrations of cocamidopropyl betaine (CAPB) and sodium lauryl sulphate (SLS) surfactants. Furthermore, the evaluation of liquid bath soap formula was performed. The characterization results showed that activated charcoal produced from SACG met the SNI requirements with a yield of 86.3%, volatile substance content of 10.67%, water content of 5.67%, ash content of 1.7%, pure carbon content of 81.96%, and iodium absorption of 1522.8 mg/g. The evaluation results revealed that liquid bath soap formula with activated charcoal from SACG containing a combination of 5% CAPB and 5% SLS (F5) was the best formula that met the requirements. SACG can be used as an excellent raw material for activated charcoal in liquid bath soap formulations.
New Insights of Response Surface Methodology Approach in Optimizing Total Phenolic Content of Zanthoxylum acanthopodium DC. Fruit Extracted Using Microwave-Assisted Extraction and the Impact to Antioxidant Activity Sumaiyah, Sumaiyah; Murwanti, Retno; Illian, Didi Nurhadi; Lubis, Muhammad Fauzan; Tampubolon, Keshia
Indonesian Journal of Chemistry Vol 24, No 6 (2024)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.95922

Abstract

Zanthoxylum acanthopodium DC., a unique spice plant from North Sumatra, is rich in beneficial secondary metabolites, particularly phenolic compounds. This study utilized the microwave-assisted extraction method to enhance the extraction of these bioactive compounds. The goal was to determine the optimal extraction conditions, including solvent concentration (X1), microwave power (X2), and extraction time (X3) to maximize the total phenolic content (TPC) of Z. acanthopodium fruit. A Box-Behnken design, part of response surface methodology, was used with three factors at three levels: X1 (50%, 75%, and 100% ethanol in water), X2 (180, 300, and 450 W), and X3 (3, 8.5, and 14 min). The phenolic compounds in the optimized extract were identified using LC-HRMS, and its antioxidant activity was measured using radical scavenging activity assays. The statistical analysis indicated a significant quadratic model (p-value < 0.05), with a high R2 of 86.25%. Optimal conditions for maximum TPC (159.637 ± 5.72 mg GAE/g) were achieved with 50% ethanol, 450 W, and 8.5 min, outperforming conventional extraction methods. Compared to the non-optimized extract, the optimized extract also exhibited strong antioxidant activity, particularly in DPPH radical inhibition. This method successfully optimized TPC in Z. acanthopodium fruit, enhancing its antioxidant properties.
Pemetaan Saintifik terhadap Potensi Tanaman Brassicaceae sebagai Anti-inflamasi: Analisis Bibliometrik Periode Tahun 2003−2024 Tivanie, Riza Ayu; Murti, Yosi Bayu; Illian, Didi Nurhadi; Nugroho, Agung Endro
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.871

Abstract

The Brassicaceae family is recognized for its antioxidant and anti-inflammatory properties. Due to its widespread distribution, it serves as a prominent source of bioactive phytochemicals, attracting considerable research interest. Brassicaceae plants contain several secondary metabolites, including glucosinolates, which are precursors to bioactive compounds like isothiocyanates (e.g., sulforaphane) that have demonstrated anti-inflammatory effects. This study aims to investigate keywords, countries, number of publications, institutions, authors, and journals related to Brassicaceae plants as anti-inflammatory agents during the period 2003–2024 using a comprehensive bibliometric analysis method. Information was collected using the Scopus database, followed by data analysis using the Biblioshiny R Package and VOSviewer. A total of 760 articles meeting the inclusion criteria were analyzed. The results indicate that 2023 saw the largest increase in research publications, with China emerging as the leading contributor, while the USA had the highest citation count. The International Journal of Molecular Sciences was identified as the most popular publishing journal. Kyung Hee University was designated as the most productive institution, with Li Y as the author with the highest contribution. Bibliometric data also highlighted several therapeutic target molecules, including cytokines, nitric oxide, cyclooxygenase-2, and Nrf2, which play crucial roles in the action mechanisms of signature metabolites from Brassicaceae plants, including sulforaphane, isothiocyanates, glucosinolates, and flavonoids, for therapeutic purposes as anti-inflammatory, antioxidant, antimicrobial, and chemopreventive agents. These findings highlight the significant potential of Brassicaceae medicinal plants for various therapeutic mechanisms and provide recommendations for future research in the pharmacy field.
PEMBERDAYAAN PETANI GARAM DI DESA LAM UJONG MELALUI TRANSFER TEKNOLOGI PEMBUATAN GARAM SPA DAN SABUN CAIR Irwan, Irwan; Illian, Didi Nurhadi; Putri, Cut Namira; Elisa, Sofia; Deria, Salsabila; Setiawan, Ichsan; Miswar, Edy; Putra, Dedi Fazriansyah; Nurliza, Eli; Azmi, Nurul
Jurnal Abdi Insani Vol 11 No 4 (2024): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v11i4.2105

Abstract

Lam Ujong Village is one of the villages in the Baitussalam sub-district of Aceh Besar Regency. The majority of people in this coastal area work as salt farmers to support their livelihoods. Despite the abundant salt production, it has not significantly increased the community's income, as salt processing is limited to selling salt directly to consumers. Processing sea salt into creative, economically valuable products has not been pursued due to a lack of innovation and skills. Sea salt is rich in minerals with great potential to be utilized as a key raw material in producing spa salts and liquid soap. This community service activity will be conducted in Lam Ujong Village in 2024, in partnership with a group of salt farmers. The project will be carried out in three stages: pre-activities (socialization and initial preparation for educational activities), main activities (training and technical guidance on producing environmentally friendly spa salt and liquid soap), and post-activities (evaluation of results).The program results demonstrated a significant improvement in the technical skills and understanding of salt farmers regarding the production process of spa salts and liquid soap. This success highlights that well-targeted technology transfer can be a key driver in the economic transformation of local communities while promoting more sustainable natural resource management. Key Word: Blue economy, Spa Salt, Liquid Soap, Salt Farmers