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All Journal Jurnal Riset Kesehatan Jurnal Ilmu Kedokteran dan Kesehatan Biopendix: Jurnal Biologi, Pendidikan dan Terapan 3BIO: Journal of Biological Science, Technology and Management BIOEDUPAT: Pattimura Journal of Biology and Learning Jurnal Inkofar JUKEJ: Jurnal Kesehatan Jompa Jurnal Sains dan Kesehatan
Mayuri, Nindya Sekar
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Education Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Transportation Veterinary

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Effectiveness of Bamboo Stick Liquid Smoke (Bamboo sp.) With Methanol Extract of Sengon Twig Wood (Falcataria moluccana) as a Disinfectant Nabillah, Hurient Sani; Sonya, Luluil Fajry Thasya; Fitriani, Dilla Saphira; Muzjahidah, Nelly Siti; Vaolina, Putri; Fadhila, Feldha; Rumidatul, Alfi; Mayuri, Nindya Sekar
Jurnal Riset Kesehatan Vol 13 No 1 (2024): MEI 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jrk.v13i1.10597

Abstract

Pathogenic microorganisms that cause infectious diseases are widely spread in the environment, especially in public places that allow microorganisms to multiply. Disinfectants are used to prevent the spread of these microorganisms. The use of chemical-based disinfectants can cause side effects, so it is necessary to look for alternatives from natural materials, such as a mixture of bamboo stem liquid smoke and methanol extract from Sengon twig wood. The purpose of this study was to determine the effectiveness of a mixture of bamboo stem liquid smoke and methanol extract of Sengon twig on bacteria and fungi. This research method began with an inhibition test of the disc and well diffusion method with five comparison treatments (50:50, 40:60, 30:70, 20:80, 10:90) to obtain the most effective comparison of the volume of 100% bamboo stem liquid smoke mixture and 11% sengon twig wood methanol extract, then tested using the Total Plate Count (TPC) method with swab samples on wooden tables. The results showed that the most effective comparison of the volume of 100% bamboo stem liquid smoke mixture and 11% sengon twig wood methanol extract was the volume ratio of 50:50 from the results of the inhibition zone on Salmonella typhimurium with a diameter of 10.3 mm. The results of the mixed effectiveness test with a ratio of 50:50 with the swab test on the table showed a decrease in the number of bacteria (51%) and fungi (65%). This shows that the mixture of bamboo stem liquid smoke and methanol extract of Sengon twig wood is effective as a disinfectant.
Toksisitas Akut dan Efek Protektif Ekstrak Etanol Schima wallichii terhadap Histopatologi Hati dan Ginjal Mencit yang Diinduksi Aloksan Risa, Tiara Nova; Rahmawati, Mutia; G R, Lutfi Khoiriyah; Kodariah, Liah; Mayuri, Nindya Sekar; Rumidatul, Alfi
JUKEJ : Jurnal Kesehatan Jompa Vol 5 No 1 (2026): JUKEJ: Jurnal Kesehatan Jompa
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jkj.Vol5.Iss1.2491

Abstract

Diabetes melitus (DM) merupakan penyakit metabolik kronis yang memicu komplikasi pada hati dan ginjal melalui mekanisme stres oksidatif. Tanaman Puspa (Schima wallichii (D.C) Korth) mengandung senyawa bioaktif antioksidan seperti flavonoid dan tanin yang berpotensi sebagai agen antidiabetes. Penelitian ini bertujuan mengevaluasi toksisitas akut serta efek protektif ekstrak etanol ranting S. wallichii terhadap gambaran histopalogi hati dan ginjal mencit (Mus musculus) yang diinduksi aloksan. Mencit jantan diinduksi aloksan 150 mg/kgBB secara intraperitoneal, kemudian diberikan ekstrak secara oral dengan dosis 98 mg/kgBB (P1) dan 196 mg/kgBB (P2). Parameter yang diamati meliputi berat badan, kadar glukosa darah, gejala toksisitas klinis, serta perubahan mikroskopis jaringan hati dan ginjal. Hasil menunjukkan tidak terdapat mortalitas maupun gejala toksik berat selama 14 hari pengamatan, sehingga nilai LD₅₀ semu dikategorikan praktis tidak toksik (>196 mg/kgBB). Secara histopatologis, kelompok P2 menunjukkan perbaikan signifikan pada jaringan hati (p < 0,05) yang ditandai dengan penurunan derajat degenerasi dan nekrosis. Pada ginjal terdapat tren penurunan skor kerusakan secara deskriptif, namun belum menunjukkan perbedaan bermakna secara statistik (p > 0,05). Dapat disimpulkan bahwa ekstrak ranting S. wallichii aman pada dosis uji, efektif memperbaiki kerusakan hati (hepatoprotektif), serta memiliki potensi nefroprotektif terbatas pada model mencit diabetes.
Co-Authors Alamsyah, Muhamad Thamrin Alifah, Aqil Anisa, Divia Arrsy, Aulia Nur Asifadilah, Ayu Dianah, Pepin Nur Fadhila, Feldha Fauzia Azzahra, Fauzia Fitriani, Dilla Saphira Fitriani, Rima G R, Lutfi Khoiriyah Hafid, Naila Akfalia Juniar, Fadia Rahma Kodariah, Liah Kusuma Handayani, Kusuma Mareta Hera Siswana, Dwi Risyani Muzjahidah, Nelly Siti Nabila, Hasna Putri Nabillah, Hurient Sani Nainggolan, Ribka Debora Ni'am, Ayu Rahayu Nurul Nurjaman, Deni Nurjana, Siti Qomariah, Annisa Nur Rahmawati, Mutia Ramadhani, Intan Puspita Rina Marlina Risa, Tiara Nova Rohmah, Fitriani Nurhidayati Rumidatul, Alfi Sonya, Luluil Fajry Thasya Sugara, Yuliannisa Tantiani, Aisyah Putri Vaolina, Putri Yuliani, Septa Yusuf, Nabila Islami Zahroh, Salsabila