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All Journal Indonesian Journal of Medicine Jaringan Laboratorium Medis ARTERI : Jurnal Ilmu Kesehatan Borneo Community Health Sevice Journal Jurnal Ilmiah Pengabdian Masyarakat Bidang Kesehatan Academic Hospital Journal
Setyowatiningsih, Lilik
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Biochemistry, Genetics & Molecular Biology Dentistry Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health

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Peningkatan Derajad Kesehatan Ibu Hamil dengan Pemantauan Kadar Hemoglobin dan Edukasi Pada Ibu Hamil Untuk Mencegah Stunting Setyowatiningsih, Lilik; Surati, Surati; Maulanah, Mochamad Rizal; Duri, Iin Desmiany
Borneo Community Health Service Journal VOLUME 4 NOMOR 1 TAHUN 2024
Publisher : Fakultas Ilmu Kesehatan Universitas Borneo Tarakan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35334/neotyce.v4i1.4988

Abstract

Maternal Mortality Rate (MMR), both during pregnancy, childbirth and postpartum, is an important thing that must be considered, as an effort to increase the health status of mothers and the life expectancy of babies born. Maternal death cases describe the mother's health status, nutritional status, environmental health conditions and the level of availability of health services and health personnel for the mother. Based on 2019 Central Java Health Office data, the maternal mortality rate was 331 cases and Sukoharjo district recorded 5 cases of maternal death. This community service activity aims to improve the level of health of pregnant women by monitoring hemoglobin levels and increasing knowledge by providing education about anemia in pregnant women and the impact of stunting. This activity was carried out in 2 stages and 3 ways, namely by providing pre, material and post. The material is delivered directly and using leaflets. The number of participants in this activity was 50 people. The results show that the average knowledge of pregnant women increased after education was provided by providing materials and leaflets.
Pengaruh Pemberian Kopi Robusta (Coffea canephora) terhadap Penurunan Kadar Glukosa Darah pada Tikus Rattus norvegicus dengan Kondisi Diabetes Melitus Sofyanita, Eko Naning; Maulana, Mochamad Rizal; Auliya, Qurrotu A'yuni; Setyowatiningsih, Lilik; Swastyaputri, Adita Puspitasari
ARTERI : Jurnal Ilmu Kesehatan Vol 5 No 3 (2024): Mei
Publisher : Puslitbang Sinergis Asa Professional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37148/arteri.v5i3.439

Abstract

Diabetes Mellitus (DM) leads to an increase in Reactive Oxygen Species (ROS), which disrupts the function of pancreatic β-cells. The dependency on medications often occurs, hence there is a need for natural remedies with antihyperglycemic properties, such as coffee. Coffee contains high levels of antioxidants like chlorogenic acid, flavonoids, and caffeine, which are exogenous antioxidants that can activate NRF-2 and increase the activity of the enzyme Superoxide Dismutase (SOD), thus acting as an antihyperglycemic agent. This study aims to determine the effect of robusta coffee on blood glucose levels in rats with DM conditions. This experimental study used a Randomized Control Pretest-Posttest Group Design. The sample in this study included 24 male Rattus norvegicus rats, aged 3 months, with a body weight of 230-250 grams, divided into 4 groups randomly after a one-week acclimation period. The DM condition was induced by administering streptozotocin at 40 mg/KgBW, followed by a pretest blood glucose level examination after 3 days of streptozotocin induction. The diabetic rats were then given robusta coffee once a day for a period of 14 days. On the 15th day, a posttest blood glucose level examination was conducted. The results showed that the control group (KN) had no significant difference (p=0.530), while the treatment groups KP (p=0.003), KK1 (p=0.013), and KK2 (p=0.000) showed significant differences (p<0.05). The conclusion of this study is that the administration of robusta coffee (Coffea canephora) can reduce blood glucose levels in rats with diabetes mellitus.
Gambaran Stabilitas Pooled plasma CPDA Sebagai Bahan Kontrol Kualitas Pemeriksaan Asam Urat Pada Uji Presisi Within run dan Between day Setyaji, Yoki; Duri, Iin Desmiany; Setyowatiningsih, Lilik
Jaringan Laboratorium Medis Vol 6, No 2 (2024): November 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i2.10933

Abstract

The quality of laboratory test results is ensured by implementing quality control measures, which usually require control materials. The high cost of commercial control materials poses a challenge for laboratory quality control. Commonly, laboratory control materials are commercial control serums derived from animal serum that undergoes lyophilization during manufacturing. This study aims to assess the stability of CPDA pooled plasma that has been frozen for 60 days, using precision tests both within-run and between-day. Methods: This experimental research utilized CPDA pooled plasma samples from hematology laboratory waste at Poltekkes Kemenkes Semarang. The samples were frozen at -20℃ for 60 days. Quality control (QC) analysis was conducted using within-run and between-day precision tests without replication, to determine the standard deviation (SD) and coefficient of variation (CV). The results were then statistically analyzed using a one-way ANOVA to assess the difference in CPDA pooled plasma stability between the within-run and between-day precision tests. The QC results for within-day and between-day precision were as follows: the average for within-day was 4.066 and for between-day 3.2785; SD for within-day was 0.20 and for between-day 0.09; CV for within-day was 4.9% and for between-day 2.9%. The one-way ANOVA test showed a significance value of 0.316, indicating no significant difference between the within-day and between-day QC methods in terms of precision testing. Conclusion: CPDA pooled plasma remains stable in maintaining the precision of QC results for uric acid using the enzymatic colorimetric method (end-point) after 60-80 days of storage and can be used as an alternative to commercial control materials in uric acid QC testing.
Effect of Bamboo Shoot (Gigantochloa Nigrociliata) Extract on Decreased Blood Pressure and Tnf-Α in Male Wistar Rats (Rattus Norvegicus) Surati, Surati; Setyowatiningsih, Lilik; Aulia, Qurrotu A’yuni; Widiyanto, Santo Yoseph Didik; Sutrisna, EM
Indonesian Journal of Medicine Vol. 8 No. 1 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Hypertension is a non-communicable disease based on increased pathologies such as RAS, inflammation, and oxidative stress. Bamboo shoot extract contains BSP, phenol, and flavonoids that can reduce inflammatory status, oxidative stress, and ACE. The study aims to determine the effect of bamboo shoot extract on decreased blood pressure and TNF-α in male Wistar Rats made hypertensive.Subjects and Method: This study used a True Experimental Design with the Posttest Only Control Group Design. The study was located at the Integrated Biomedical Laboratory of the Faculty of Medicine, Sultan Agung Islamic University, Semarang in April-July 2021. The study sample of 24 male Wistar Rats was randomly divided into 4 groups. The dependent variables of the study were Blood pressure and TNF-α. The independent variable was bamboo shoot extract. Blood pressure was measured by Pressure Recording Tail Cuff, and TNF-α was measured by using the ELISA method with CATALOG Number KET 9007-48 well. The data were analyzed by using the One Way Anova Test.Results: This study showed no significant difference from systolic or diastolic blood pressure results of male Wistar rats in the K1, K2, and K3 groups after the intervention. Meanwhile, the average levels of TNF-α decreased significantly in the K3 group (Mean= 1.99; SD= 1.13) compared with the control group K0 (Mean= 16.70; SD= 7.45) and it was statistically significant p<0.001.Conclusion: There is no significant effect on blood pressure in male Wistar rats that obtained bamboo shoot extract, but there is a significant effect on TNF-α levels in male wistar rats that obtained bamboo shoot extract.Keywords: bamboo shoots, hypertension, blood pressure, TNF-α, male wistar rat.Correspondence: Surati. Department of Cytohistotechnology, Study Program of Health Analyst, Health Polytechnic, Ministry of Health Semarang. Jl. Wolter Monginsidi No. 115, Pedurungan, Semarang, Central Java, Indonesia, Email: analis_surati@yahoo.com. Mobile: 085226825024.Indonesian Journal of Medicine (2023), 08(01): 121-127https://doi.org/10.26911/theijmed.2023.08.01.12 
Hemoglobin Levels in PRC Blood Products Before and After Shelf Life Period Ranika Puteri, Orchelanesya Avrilia; Setyaji, Yoki; Setyowatiningsih, Lilik
Academic Hospital Journal Vol 7, No 2 (2025)
Publisher : Rumah Sakit Akademik Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ahj.v7i2.106350

Abstract

Background: PRC is a component found in living creatures, which plays an important role in transporting oxygen and metabolic products to body tissues. PRC transfusion is indicated at Hb levels < 7.0 g/dl, especially in patients with acute anemia. In the transfusion process, before there is a request for blood to be transfused, the blood will be stored in a blood bank. A good blood storage process is needed to maintain the quality of blood products so that they are safe for transfusion. During the storage process, hemoglobin levels in the blood can change. The longer blood is stored, the more red blood cells become fragile and lyse, thereby increasing the concentration of hemoglobin in the blood. This study aims to determine and describe the description of hemoglobin levels in pre- and post-PRC blood products during the shelf life at UDD PMI Rembang Regency.Method: This type of research uses analytical descriptive research and a research design with purposive sampling techniques. The samples used in this study were 30 bags of PRC blood, which met the inclusion and exclusion criteria.Result:  The results of this study showed an increase in hemoglobin levels, with the average pre-storage hemoglobin level being 14.99 g/dl, while the average post-storage hemoglobin level was 17.5 g/dl.Conclusion: In this study, there was an average increase in hemoglobin levels of 2.51 g/dl or 16.74%. This could be caused by temperature, storage time, and anticoagulants.
Hubungan Antara Higiene Sanitasi Terhadap Kontaminasi Telur Cacing Non STH Pada Sayur Lalapan di Warung Makan Setyowatiningsih, Lilik; Wikandari, Ririh Jatmi; Surati, Surati
Jaringan Laboratorium Medis Vol. 4 No. 1 (2022): May 2022
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v4i1.8325

Abstract

Fresh vegetables can be a source of transmission of worm infections to humans. The behavior of washing fresh vegetables that are not good by housewives and sellers of fresh vegetables in food stalls becomes large in transmitting worm infections if there are worm eggs that are still attached to fresh vegetables. The most common contamination found in fresh vegetables were eggs of the intestinal nematode Soil Transmitted Helminths (STH) as well as non-STH and trematodes. The purpose of this study was to determine the relationship between sanitation hygiene and contamination of non-STH worm eggs in fresh vegetables at food stalls in Semarang City. This type of research is an observational study with a cross sectional approach. Based on the results of laboratory tests, from a total of 165 samples examined, eggs of non-STH worms with species of Fasciola sp and Toxocara sp were found in 45 food stalls selling fresh vegetables. Based on bivariate analysis, there was no significant relationship between personal hygiene (p = 0.071) and environmental sanitation (p = 0.334) on contamination of non-STH worm eggs in fresh vegetables in food stalls in Pedurungan District, Semarang.
Faktor-faktor Risiko Kelainan Kadar Hemoglobin pada Pengendara Ojek Motor Online di Kawasan Industri Tanjung Mas Kota Semarang Setyowatiningsih, Lilik; Wikandari, Ririh Jatmi
Jaringan Laboratorium Medis Vol. 5 No. 2 (2023): November 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i2.9564

Abstract

Air pollution can affect health conditions, CO and Pb are one of the compositions of vehicle exhaust gases that are dangerous. Online motorcycle taxi drivers have a high risk of exposure to pollutants. This research aims to determine the risk factors that affect hemoglobin levels in online motorcycle taxi drivers in the Tanjung Emas Area of Semarang City. The method used observational analytics with a cross-sectional approach. The total population in this study was 55 respondents and the number of respondents was determined using total sampling. Based on the results of examining hemoglobin levels using a hematology analyzer, of 55 respondents, 47 respondents had normal hemoglobin levels and 8 respondents had abnormal hemoglobin levels. The results of the Chi square test on smoking status have a significant relationship (p=0.04) to the blood hemoglobin level of online motorcycle taxis in the Tanjung Emas Area of Semarang city while in the status of Education, length of work, and knowledge there is no significant relationship (>0.05) to the hemoglobin level of online motorcycle taxi drivers in the Tanjung Emas Area of Semarang City. The conclusion of this study is that there is a significant relationship between smoking status and hemoglobin levels of online motorcycle taxi drivers in the Tanjung Emas Area of Semarang City and there is no significant relationship between education factors, length of work time, and knowledge of hemoglobin levels of online motorcycle taxis in the Tanjung Emas Area of Semarang City.
Gambaran Stabilitas Pooled plasma CPDA Sebagai Bahan Kontrol Kualitas Pemeriksaan Asam Urat Pada Uji Presisi Within run dan Between day Setyaji, Yoki; Duri, Iin Desmiany; Setyowatiningsih, Lilik
Jaringan Laboratorium Medis Vol. 6 No. 2 (2024): November 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i2.10933

Abstract

The quality of laboratory test results is ensured by implementing quality control measures, which usually require control materials. The high cost of commercial control materials poses a challenge for laboratory quality control. Commonly, laboratory control materials are commercial control serums derived from animal serum that undergoes lyophilization during manufacturing. This study aims to assess the stability of CPDA pooled plasma that has been frozen for 60 days, using precision tests both within-run and between-day. Methods: This experimental research utilized CPDA pooled plasma samples from hematology laboratory waste at Poltekkes Kemenkes Semarang. The samples were frozen at -20℃ for 60 days. Quality control (QC) analysis was conducted using within-run and between-day precision tests without replication, to determine the standard deviation (SD) and coefficient of variation (CV). The results were then statistically analyzed using a one-way ANOVA to assess the difference in CPDA pooled plasma stability between the within-run and between-day precision tests. The QC results for within-day and between-day precision were as follows: the average for within-day was 4.066 and for between-day 3.2785; SD for within-day was 0.20 and for between-day 0.09; CV for within-day was 4.9% and for between-day 2.9%. The one-way ANOVA test showed a significance value of 0.316, indicating no significant difference between the within-day and between-day QC methods in terms of precision testing. Conclusion: CPDA pooled plasma remains stable in maintaining the precision of QC results for uric acid using the enzymatic colorimetric method (end-point) after 60-80 days of storage and can be used as an alternative to commercial control materials in uric acid QC testing.
Mentoring and Empowerment Diploma Three Student in Blood Bank Technology, Health Polytechnic, Ministry of Health, Semarang, Through Training in Making Soy Milk as an Effort to Prevent Anemia Afrianti, Dina; Hartono, Rodhi; Setyowatiningsih, Lilik; Sofyanita, Eko Naning; Wahyudi
Jurnal Ilmiah Pengabdian Masyarakat Bidang Kesehatan (Abdigermas) Vol. 2 No. 1 (2024): Jurnal Ilmiah Pengabdian Kepada Masyarakat Bidang Kesehatan (Abdigermas)
Publisher : CV Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/abdigermas.v2i1.169

Abstract

Mentoring participants know about anemia and its symptoms. Participants know the equipment and materials needed to make soy milk and know the steps on how to make soy milk and participants are able to give a demonstration of making soy milk to the residents of the target village. Residents of the assisted villages know how to make soy milk. Community service activities with the Entrepreneurship Development Program (PPK) scheme with the theme "Assistance in the Empowerment of Diploma Three Technology Students at the PolkesMar Blood Bank through training in making soy milk (Soymilk) as an effort to prevent anemia" was carried out on Friday 28 July 2023 with a target of 10 people participating. consisting of 8 active students and 2 alumni. The output is in the form of videos and pamphlets on making soy milk that have received IPR certificates as well as the expertise of training participants resulting from a series of training activities on making soy milk (Soymilk) targeting students and alumni. This has also been implemented in community service activities for the target village residents in Pundan Hamlet, Subdistrict. Kebondowo Banyubiru, Semarang district, which will be held on Sunday 15 October 2023. The successful achievement of this activity was that all participants in the training on making soy milk were able to give demonstrations on making soy milk to the residents of the target villages. Residents of the assisted villages were given education about anemia and solutions to preventing anemia, the committee also showed videos of making soy milk, distributed pamphlets and gifts to residents of the assisted villages.
Co-Authors Aulia, Qurrotu A’yuni Auliya, Qurrotu A'yuni Dina Afrianti1 Duri, Iin Desmiany Eko Naning Sofyanita Em Sutrisna Maulana, Mochamad Rizal Ranika Puteri, Orchelanesya Avrilia Ririh Jatmi Wikandari Rodhi Hartono Setyaji, Yoki Sofyanita, Eko Naning Surati Surati Swastyaputri, Adita Puspitasari WAHYUDI Widiyanto, Santo Yoseph Didik