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HUBUNGAN KADAR ENZIM ASETILKOLINESTERASE TERHADAP KADAR GLUKOSA PETANI YANG TERPAJAN PESTISIDA Suhartono, Eko; Edyson, Edyson; Budianto, Windy Yuliana; Sekartaji, Hapsari Lintang; Fahira, Nurul Savira; Cahyadi, Herry
Jurnal Publikasi Kesehatan Masyarakat Indonesia Vol 5, No 2 (2018): Jurnal Publikasi Kesehatan Masyarakat Indonesia
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jpkmi.v5i2.5482

Abstract

AbstrakPestisida merupakan bahan kimia yang digunakan untuk mengendalikan serangga, jamur, gulma dan lain-lain. Penggunaan pestisida yang tak terkendali menyebabkan keracunan dan berdampak pada ganguan metabolisme. Untuk membuktikan hal tersebut telah diteliti hubungan antara kadar enzim asetilkolinesterase dengan kadar glukosa darah petani yang terpajan pestisida. Rancangan penelitian ini bersifat analitik, dengan pendekatan cross sectional. Subjek penelitian adalah seluruh anggota kelompok tani Kurnia Makmur di Kecamatan Landasan Ulin Utara Banjarbaru dengan menggunakan jumlah sampel minimal sebesar 60 orang. Pemeriksaan sampel kadar enzim asetilkolinesterase dalam darah dan glukosa dalam darah dilakukan dengan bekerjasama dengan Labkesda Kabupaten Banjar dengan No. 001/LKA/C/VII/2016 s/d 60/LKA/C/VII/2016. Data dikumpulkan dari Dinas Kesehatan Banjarbaru tahun 2016. Analisis bivariat digunakan untuk menjelaskan hubungan dua variabel yaitu antara kadar kolinesterase dengan kadar glukosa darah dengan menggunakan uji Spearman dengan derajat kepercayaan 95%. Hasil penelitian didapatkan rerata kadar asetilkolinesterase pada petani berjenis kelamin laki-laki dan perempuan melebihi batas normal (L= 4,6-11,5 U/L; P=3,9-10,8 U/L). Hal ini menandakan bahwa sebanyak 63,34% petani mengalami keracunan pestisida. Sementara itu, rerata kadar glukosa darah petani masih tergolong normal (Gula darah sewaktu „T 125 mg/dL) meskipun pada petani berjenis kelamin wanita ditemukan sebanyak 5% mengalami hiperglikemia. Hasil uji Spearman didapat r =0,049 (p=0,768; p>0,05) yang berarti tidak ada hubungan yang bermakna antara kadar asetilkolinesterase dengan kadar glukosa darah petani yang terpajan pestisida.Kata-kata kunci: Pestisida, kolinesterase, glukosa, diabetesAbstractPesticides are chemicals used to control insects, fungi, weeds and others. Uncontrolled use of pesticides causes poisoning and affects metabolic disorders. To prove the above has been investigated the relationship between the levels of enzyme acetylcholineserase with blood glucose levels of farmers exposed to pesticides. The design of this study is analytic, with cross sectional approach. Research subjects were all members of Kurnia Makmur farmer group in Kecamatan Landasan Ulin Utara Banjarbaru by using minimum sample amount of 60 people. Examination of samples of cholinesterase enzyme levels in blood and glucose in blood was done in collaboration with Labkesda Kabupaten Banjar with no. 001 / LKA / C / VII / 2016 s / d 60 / LKA / C / VII / 2016. Data was collected from Banjarbaru Health Office in 2016. Bivariate analysis was used to explain the relationship between two variables, ie, between cholinesterase and blood glucose level using Spearman test with 95% confidence degree. The result showed that the level of acetylcholinesterase in male and female farmers exceeded the normal limit (L = 4.6-11.5 U / L; P = 3.9-10.8 U / L). This indicates that as many as 63.34% of farmers are poisoned by pesticides. Meanwhile, the average blood glucose level of farmers is still normal (blood sugar at „T 125 mg / dL) although the female-female farmers found as many as 5% had hyperglycemia. Spearman test result obtained r = 0.049 (p = 0.768; p> 0.05) meaning there is no significant relation between level of acetylcholinesterase with blood glucose level of farmer exposed by pesticide.Keyword: pesticide, acetylcholinesterase, glucose, diabettes
Bibliometric Analysis of Lead's Effects on the Nervous System Sekartaji, Hapsari Lintang; Hartoyo, Edi; Febriana, Silvia Kristanti Tri; Noor, Zairin; Sanyoto, Didik Dwi; Iskandar, Iskandar
Berkala Kedokteran Vol 20, No 2 (2024)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v20i2.20536

Abstract

Lead (Pb) is a heavy metal that is proven to cause various health problems. In its development, research trends on the effects of Pb on the nervous system are still a topic of research. This study aims to identify trends, research focus, and research contributions to understanding the impact of Pb on the nervous system. The method used, namely bibliometric analysis with the help of Publish or Perish (POP) with the keyword Pb on autism and VOS Viewer software and Scopus database. Keyword analysis was conducted on 131 documents from 2013-2024. The results concluded that there are 4 keywords, namely child, lead, effect, and metal and have a great opportunity for future research. This analysis also found that the article entitled "Mechanisms of lead and manganese neurotoxicity" was the most cited article, with 153 citations.
Domestic Wastewater Treatment to Control River Pollution in Sungai Pinang, Samarinda, East Kalimantan Suhartono, Eko; Erlena, Erlena; Sekartaji, Hapsari Lintang; Putera, Gusti Muhammad Perdana; Thalib, Iskandar; Syauqiah, Isna; Hafifah, Ifa; Trang, Ha Thi Thu
Jurnal Presipitasi : Media Komunikasi dan Pengembangan Teknik Lingkungan Vol 21, No 3 (2024): November 2024
Publisher : Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/presipitasi.v21i3.869-878

Abstract

Filtration is a method for controlling water pollution. This study aimed to engineer a filtration system using a combination of Melaleuca cajuputi (galam) wood charcoal and zeolite to process domestic wastewater. The research focused on domestic wastewater from Sungai Pinang Village, Samarinda, East Kalimantan, an area with significant water pollution issues. The samples were divided into three groups, each containing zeolite and galam wood charcoal in different ratios: Group 1 (1:1), Group 2 (1:2), and Group 3 (2:1). Each sample was exposed to contact times of 30, 60, and 90 minutes. Biological Oxygen Demand (BOD), Chemical Oxygen Demand (COD), Ammonia (NH3), and pH were measured for each treatment group at each contact time. Results showed that prolonged contact with the filtration method significantly reduced all parameters except pH (P<0.05). Each treatment combination did not significantly reduce all parameters except pH (P>0.05). Group 2 was found to be the most effective in improving water quality. In conclusion, this study demonstrates that the filtration method can reduce pollutant levels, with the combination of galam wood charcoal and zeolite in a 2:1 ratio being the most effective.