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All Journal Jurnal Ilmiah Biosaintropis (Bioscience-Tropic) JOPS (Journal Of Pharmacy and Science) Jurnal Kreativitas PKM JCPS (Journal of Current Pharmaceutical Sciences) Journal Syifa Sciences and Clinical Research (JSSCR) Jurnal Riset Kefarmasian Indonesia Kampurui Jurnal Kesehatan Masyarakat Jurnal Insan Farmasi Indonesia Journal of Applied Nursing and Health Gemakes: Jurnal Pengabdian Kepada Masyarakat Jurnal Farmasi Sains dan Praktis Nutriture Journal Jurnal Pendidikan Kesehatan (e-Journal) Parapemikir Jurnal Ilmiah Farmasi PRIMER: Jurnal Ilmiah Multidisiplin Health Care Media
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Analisis Kandungan Asam Retinoat Pada Krim Pemutih Di Pasar Singosari Kabupaten Malang Dengan Menggunakan Uji Warna SbCl3 Dan Kromatografi Lapis Tipis Mahmudah, Annida Lutfa; Jayadi, Lukky; Sabila, Nurma
PRIMER : Jurnal Ilmiah Multidisiplin Vol. 2 No. 3 (2024): PRIMER : Jurnal Ilmiah Multidisiplin, Juni 2024
Publisher : LPPM Institut Teknologi Dan Kesehatan Aspirasi

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Asam retinoat merupakan bahan yang dilarang dalam kosmetik berdasarkan Peraturan Kepala BPOM No: HK.00.05.42.1018 tentang Bahan Kosmetik. Akan tetapi selama lima tahun terakhir, penambahan asam retinoat masih ditemukan pada berbagai sediaan kosmetik, salah satunya yaitu krim pemutih. Sehingga, penelitian ini bertujuan untuk mengetahui ada tidaknya kandungan asam retinoat pada krim pemutih di Pasar Singosari Kabupaten Malang. Sampel yang diteliti adalah 11 krim pemutih tanpa nomer izin BPOM. Pemeriksaan kualitatif secara bertahap dilakukan dengan uji warna menggunakan pereaksi antimon triklorida (SbCl3) dan metode Kromatografi Lapis Tipis (KLT) dengan fase diam lempeng KLT silika gel 60F254 dan fase gerak n-heksan – asam asetat glasial 0,33% dalam etanol p.a (9:1) v/v. Hasil uji warna menunjukkan bahwa empat sampel diduga mengandung asam retinoat (sampel D, E, F, dan H) ditandai dengan hasil uji warna yang sama dengan kontrol positif yaitu ungu. Sampel yang diduga positif tersebut dilanjutkan untuk dianalisis dengan KLT dan hasilnya negatif mengandung asam retinoat karena nilai Rf sampel tidak sama dengan larutan standar asam retinoat. Nilai Rf sampel D dan E yaitu 0,013 dan 0,034, sedangkan nilai Rf dari baku asam retinoat yaitu 0,175. Dari hasil penelitian ini dapat disimpulkan bahwa 11 sampel krim pemutih yang diteliti dinyatakan negatif mengandung asam retinoat.
ANALISIS KANDUNGAN HYDROQUINONE TERHADAP KEAMANAN PADA KRIM PEMUTIH HERBAL YANG DIPERJUALBELIKAN DI PASAR BESAR KEPANJEN KABUPATEN MALANG Lukky Jayadi
Health Care Media Vol 5 No 2 (2021): Jurnal Healthcare Media
Publisher : ITKM WIDYA CIPTA HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70633/2721-6993.169

Abstract

Abstrak Krim pemutih herbal merupakan produk yang mengandung bahan aktif herbal yang menekan atau menghambat pembentukan melanin yang akan menghasilkan kulit lebih cerah. Hydroquinone sering disalahgunakan sebagai pemutih tambahan pada kosmetik yang bertujuan untuk menarik perhatian konsumen dan menghemat biaya produksi karena harganya yang murah. Penelitian ini merupakan penelitian eksperimental dan bertujuan untuk mengetahui apakah krim pemutih herbal yang diperjualbelikan di Pasar Besar Kepanjen Kabupaten Malang mengandung hydroquinone. Populasi dalam penelitian ini adalah pedagang yang menjual krim pemutih herbal di Pasar Besar Kepanjen Kabupaten Malang. Penelitian ini meneliti 4 sampel yang diambil dengan menggunakan teknik purposive sampling. Pengujian kandungan hydroquinone pada krim pemutih herbal ini dilakukan dengan metode reaksi warna FeCl3 dan KLT (Kromatografi Lapis Tipis). Hasil dari pengujian pereaksi warna sampel C dan D positif mengandung hydroquinone dengan berubah warna menjadi hitam. Pengujian dengan kromatografi lapis tipis didapat hasil kedua sampel yaitu sampel C dan D positif mengandung hydroquinone dengan ditandai adanya bercak warna ungu yang sejajar dengan baku standar hidrokuinon dan nilai Rf sebesar 0,2. Berdasarkan hasil penelitian diperoleh bahwa kedua krim herbal tersebut tidak memenuhi SNI (Standar Nasional Indonesia) nomor 16-4954-1998 tentang Persyaratan Krim Pemutih Kulit dan Peraturan Kepala Badan POM Republik Indonesia Nomor 23 tahun 2019 Tentang Persyaratan Teknis Bahan Kosmetika. Kata kunci: Hydroquinone, krim pemutih herbal, FeCl3, KLT Abstract Herbal whitening cream is a product that contains active ingredients that suppresses or inhibits the formed melanin which will produce brighter skin. Hydroquinone is often misused as an additional bleaching in cosmetics that aims to attract the attention of consumers and save production costs because of the low price. This research is an experimenta research which aims to determine whether the herbal whitening creams that are sold in Pasar Besar Kepanjen, Malang contain hydroquinone. The population in this research were traders who sell herbal whitening creams at Pasar Besar Kepanjen, Malang. This research examined 4 samples taken using purposive sampling technique. The results of testing the color reagent samples positive C and D contain hydroquinone by changing their color into black. Tests with Thin Layer Chromatography (TLC) obtained the results of the two samples, namely samples positive C and D contain hydroquinone, marked by a parallel purple spot which is equal with hydroquinone standard and Rf value of 0,2. Based on the results of the study, it was found that the two herbal creams unqualified in SNI (Indonesian National Standard) number 16-4954-1998 concerning Requirements for Skin Whitening Cream and Regulation of the Head of POM Republik Indonesia Number 23 of 2019 concerning Technical Requirements for Cosmetics Ingredients. Keywords: Hydroquinone, herbal whitening cream, FeCl3, TLC
ANALISIS ZAT PEWARNA MERAH RHODAMIN B PADA GULA KAPAS DI KABUPATEN PASURUAN Nisa, Manzila Fitrotun; Jayadi, Lukky; Fajar, Ibnu
Jurnal Pendidikan Kesehatan (e-Journal) Vol. 11 No. 1 (2022): Jurnal Pendidikan Kesehatan (E-Journal)
Publisher : Poltekkes Kemenkes Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31290/jpk.v11i1.2718

Abstract

Rhodamine B is a synthetic dye that is used to dye textiles, but it is often misused to color a street food product such as cotton sugar. The short term effects of Rhodamin B if it comes in contact with the skin or eyes are irritation of the affected area, acute poisoning, abdominal pain, vomiting, diarrhea, headaches, dizziness and hypersalivation. While the long-term effects caused are irritation of the gastrointestinal tract, disorders of several reproductive functions such as infertility or infertility, damage to liver and kidney function. This research was conducted to determine the use of Rhodamine B dye in cotton sugar in Pasuruan Regency. The cotton sugar used as the sample was taken from 3 different places, namely Markets (sample A), Town Square (sample B) and Store (sample C) representing the Pasuruan district. Analysis of cotton sugar was carried out by the color drawing method using wool yarn with Thin Layer Chromatography (TLC). The results showed that the three samples were negative and did not contain Rhodamine B red dye, this can be seen from the Rf value which cannot be calculated because on the KLT plate no orange stain was formed under the 366 nm UV lamp. It can be concluded that cotton sugar in Pasuruan Regency is safe for consumption because it does not contain red dye Rhodamin B
TAPIS BAHAYA RISIKO STUNTING MELALUI PEMBERDAYAAN MASYARAKAT DAN PENDAMPINGAN KELUARGA DI KELURAHAN MULYOREJO KOTA MALANG: TACKLING THE DANGERS OF STUNTING THROUGH COMMUNITY EMPOWERMENT AND FAMILY ASSISTANCE IN MULYOREJO SUB-DISTRICT MALANG CITY Dwipajati, Dwipajati; Astuti, Erlina; Tyas, Maria Ciptaning; Ernawati, Naya; Kurniasari, Fitriana; Pertami, Sumirah Budi; Jayadi, Lukky; Trisnanto, Puguh Yudho
GEMAKES: Jurnal Pengabdian Kepada Masyarakat Vol. 5 No. 3 (2025): GEMAKES: Jurnal Pengabdian Kepada Masyarakat
Publisher : Politeknik Kesehatan Kemenkes RI Jakarta I

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36082/gemakes.v5i3.2739

Abstract

Masalah makan pada balita seringkali menjadi salah satu faktor penyebab terjadinya balita stunting. Ibu balita menjadi penentu keberhasilan praktek pemberian makan balita. Sedangkan kader posyandu merupakan penggerak masyarakat yang turut ambil bagian dalam mentransfer informasi terkait gizi dan kesehatan dalam mendukung tumbuh kembang balita. Sehingga pengabdian masyarakat ini bertujuan meningkatkan kemampuan kader dalam mendeteksi gangguan tumbuh kembang pada balita yang mengarah pada kondisi stunting dan juga peningkatan kemampuan ibu balita dalam menyiapkan makanan balita stunting sehingga berdampak pada pertambahan tinggi dan berat badan. Hasil kegiatan ini menunjukkan adanya peningkatan pengetahuan kader posyandu yang masuk kategori baik dalam mendeteksi gangguan tumbuh kembang baik dari segi antropometri atau penggunaan form skrining (KPSP). Selain itu terjadi peningkatan peningkatan keterampilan Ibu balita dalam menyiapkan makan sehingga nafsu makan anak membaik. Nafsu makan yang membaik menyebabkan peningkatan berat badan dan tinggi badan balita dengan rerata peningkatan berat badan selama 1 bulan sebesar 420 gram dan pertambahan tinggi badan sebesar 1,88 cm. Program  pengabdian masyarakat pendampingan pada keluarga balita stunting yaitu menjadi salah satu terobosan baru  dalam  penentuan strategi  yang  efektif  dan  terintegrasi,  berbasis  masyarakat  untuk menurunkan  resiko  stunting.
Pre-Clinical Laboratory Evaluation of Chlorhexidine for Disinfection of Semi-Critical Respiratory Equipment in Nursing Practice Ariningpraja, Rustiana Tasya; Ulfa, Marina; Jayadi, Lukky; Maslukha, Andini; Effendy, Nuraeni
Journal of Applied Nursing and Health Vol. 8 No. 1 (2026): Journal of Applied Nursing and Health
Publisher : Chakra Brahmanda Lentera Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55018/janh.v8i1.546

Abstract

Background: Healthcare-associated infections (HAIs) remain a persistent challenge in nursing practice, particularly in the reprocessing of semi-critical respiratory equipment. Although chlorhexidine is widely used as an antiseptic, evidence regarding its pre-clinical disinfectant performance, physicochemical suitability, and waste safety within nurse-led device reprocessing workflows remains limited. This gap is especially relevant in settings where reusable respiratory devices are routinely handled by nurses. Methods: This study employed a pre-clinical experimental laboratory design. The independent variable was chlorhexidine concentration, while dependent variables included antimicrobial efficacy (phenol coefficient), physicochemical parameters (pH, specific gravity, viscosity), and acute toxicity. Antimicrobial testing was conducted against Staphylococcus aureus and Pseudomonas aeruginosa. Physicochemical assessments followed standardized laboratory procedures, and acute toxicity was evaluated using Danio rerio (zebrafish) larvae to inform waste disposal safety. Expert validation was conducted using the Content Validity Index (CVI). Descriptive and endpoint-based analyses were applied without inferential statistics. Results: Chlorhexidine demonstrated strong bactericidal activity against both test organisms, with phenol coefficient values indicating effective disinfectant performance. Physicochemical characteristics remained within acceptable ranges for semi-critical respiratory device reprocessing. Toxicity assessment showed dose-dependent larval mortality, indicating the need for dilution before waste discharge. Expert validation identified chlorhexidine 7.5% as the most clinically relevant concentration for nurse-led practice. No p-values were applied due to the endpoint-based experimental design. Conclusion: Chlorhexidine shows effective pre-clinical disinfectant potential for semi-critical respiratory equipment within controlled laboratory conditions. Its application in nursing practice should be accompanied by standardized concentration control and mandatory dilution before disposal to mitigate environmental toxicity. Further clinical and field-based validation is recommended.
ANALISIS PEWARNA RHODAMIN B DAN PENGAWET NATRIUM BENZOAT PADA SAUS TOMAT YANG DIPERDAGANGKAN DI PASAR BESAR TRADISIONAL KOTA MALANG Jannah, Orchidosia Zukhruffin; Suwita, Komang; Jayadi, Lukky
Jurnal Riset Kefarmasian Indonesia Vol. 3 No. 1 (2021): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v3i1.105

Abstract

One type of food product that usually uses food additives in the form of coloring agents and preservatives is sauce. Tomato sauce is a pasta-shaped product with a distinctive aroma of tomatoes. The number of sauces containing hazardous substances circulating in the community because of the increasing number of emerging home industries that do not use the correct rules for making sauces. The purpose of this study is to analyze the content of Rodhamin B coloring agents and levels of preservative Sodium Benzoate in tomato sauce traded in the Traditional Market of Malang City. The design of this study is observational, which is to dig data about the quality of tomato sauce in Malang City's Big Market by looking at the content of Rhodamin B Content and Sodium Benzoate. From the results of the study note that all tomato sauce samples do not contain Rodhamin B, while 2 of the 3 samples contain sodium benzoate preservative which exceeds the maximum threshold of 1gr / kg. Therefore, the public must be careful in buying tomato sauce products or other products that can be harmful to health.
ANALISIS KANDUNGAN PEMANIS BUATAN SIKLAMAT PADA SIRUP YANG BEREDAR DIPASAR BESAR MALANG SECARA KUANTITATIF MENGGUNAKAN METODE SPEKTROFOTOMETRI UV-VIS Jayadi, Lukky; Hernaningsih, Maritha
Jurnal Riset Kefarmasian Indonesia Vol. 3 No. 3 (2021): Jurnal Riset Kefarmasin Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v3i3.184

Abstract

Sweeteners are chemical compounds that are often added and used for industrial food processing products as well as beverages and foods, sweeteners consist of natural sweeteners and synthetic sweeteners, one of the synthetic sweeteners is sodium cyclamate. This study aims to identify and determine the level of sodium cyclamate in syrup by UV spectrophotometry method and to determine the level of sodium cyclamate in syrup is still safe for consumption. The type of research is experimental and descriptive. The research sample used is syrup which is sold in the big market of Malang City. The method used for the determination of sodium cyclamate levels was done by UV spectrophotometry whose absorption was measured at a maximum wavelength of 314 nm. The results of the quantitative analysis showed that there were positive samples containing sodium cyclamate, namely sample 1, sample 2 and sample 3. The assay results in sample 1 were 238.78 mg/kg, sample 2 was 239.65 mg/kg and sample 3 was 241.39 mg/kg. Of the three samples tested for levels of cyclamate in syrup sold in the big market in Malang City, they still meet the requirements set by the head of the Food and Drug Supervisory Agency.
FORMULASI LULUR BODY SCRUB BERAS KETAN HITAM (ORYZA SATIVA VAR. GLUTINOSA) DENGAN PERPADUAN YOGURT SEBAGAI ZAT AKTIF Agata, Shelly Dwi; Jayadi, Lukky
Jurnal Riset Kefarmasian Indonesia Vol. 4 No. 3 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i3.293

Abstract

Scrub is a cosmetic preparation for skin care that functions as an abrasive in the form of scurb granules that can remove dead skin cells from the epidermis. The scrub used in this study was derived from black glutinous rice (Oryza Sativa Var. Glutinosa) which contains antioxidant components and can help activate vitamin B1 which helps maintain healthy skin and helps skin look brighter. In addition, the components of the active substance are also needed. Yogurt was chosen as the active ingredient of the preparation because it has Alpha Hydroxy Acid (AHA) which can help the exfoliation process and help remove dead skin cells and increase the skin's natural moisture factor. The purpose of making body scrub preparations using yogurt as an active substance with varying concentrations of 0%, 5%, 10% and 15%. This research was conducted experimentally. The physical quality test of the preparation includes organoleptic test, homogeneity test, pH test, adhesion test, dispersibility test, stability test, and emulsion type test. The results show that the preparations made meet the physical evaluation of the scrub preparations meet the quality requirements, meet the organoleptic quality evaluation, namely the formulation of the scrub preparations F0, F1, F2, and F3 with semi-solid texture, purplish gray color with a mixture of black glutinous rice and yogurt. Each preparation is homogeneous. Emulsion type o/w. pH ranged from 7, 45 - 6, 74. It complies with the quality requirements of the spreadability test and has good emulsion stability. The conclusion of this study is that the F3 formulation with the addition of 15% yogurt has the best physical quality in the organoleptic test, homogeneity test, pH test, dispersibility test, stability test, and emulsion type test.
Co-Authors Agata, Shelly Dwi Anisatur Rahmah Kurniawan Ariningpraja, Rustiana Tasya Astuti, Erlina Dwipajati, Dwipajati Effendy, Nuraeni Fitri Ratnasari Hernaningsih, Maritha I Komang Suwita Ibnu Fajar Ikayanti, Retno Indra, Febryan Feriza Jannah, Orchidosia Zukhruffin Kurniasari, Fitriana Mahmudah, Annida Lutfa Maslukha, Andini Naya Ernawati Nisa, Manzila Fitrotun Nurma Sabila Pertami, Sumirah Budi Sandry Kesuma Shelly Dwi Agata Siti Cholifah Trisnanto, Puguh Yudho Tyas, Maria Ciptaning Ulfa, Marina Wattiheluw, Muhammad Hasan zuri rismiarti