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All Journal Medicinus : Jurnal Kedokteran Jurnal Impresi Indonesia
Ilmiani, Tasya Khalis
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Religion Economics, Econometrics & Finance Education Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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The Role of Probiotics in Preventing Post-Appendectomy Complications in Obese Child: A Case Report Ilmiani, Tasya Khalis; Sianturi, Efry Theresia; Musyayyadah, Musyayyadah; Ernawati, Tutik
Jurnal Impresi Indonesia Vol. 4 No. 10 (2025): Jurnal Impresi Indonesia
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jii.v4i10.7091

Abstract

Appendicitis is an inflammation of the appendix that often occurs in children. Appendectomy is the primary treatment. Obese children have a higher risk of having post-operative complications. Probiotics play a role in maintaining a balanced gut flora, potentially accelerating post-operative recovery. Case: A 12-year-old boy, weighing 50 kg, standing 140 cm tall, and with a BMI of 25.5 kg/m² (above the 95th percentile according to the CDC 2000), was diagnosed with acute appendicitis and underwent a laparoscopic appendectomy. On the first postoperative day, the patient experienced constipation and abdominal distension. He received a total energy intake of 1,300 kcal/day and was given two sachets of probiotics (Lactobacillus acidophilus, Bifidobacterium longum, and Streptococcus thermophilus) daily. On the third day, his abdominal distension decreased, and his bowel pattern improved. Discussion: Obesity causes changes in the gut microbiota, increases inflammation, and slows gut motility and wound healing. Studies show that a combination of probiotics can lower the risk of constipation and post-operative infection. The motility of the gastrointestinal tract can improve, and the inflammation will reduce. Probiotics also play a role in gut health by increasing the production of short-chain fatty acids. In this case, probiotic administration is supporting its use in post-appendectomy recovery in obese children by showing a rapid symptom improvement. Conclusion: Probiotics can help accelerate post-appendectomy recovery in obese children by balancing the gut microbiota, reducing inflammation, and improving gut motility.
The Role of Glycemic Load, Dairy, and Fatty Acids in Acne Disorders: A Systematic Review and Meta-Analysis Limanda, Claudia Felicia; Mathlubaa, Asya; Istikanto, Ferdian Harum; Sisca; Nabila, Yusra; Amalia, Shania Rizky; Putri, Syafira Ayudiah Syah; Ilmiani, Tasya Khalis; Hartanto, Ericko; Nurfadhila, Melinda
Medicinus Vol. 15 No. 1 (2025): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v15i1.10771

Abstract

Background: Modern dietary patterns characterized by high glycemic load, dairy consumption, and imbalanced fatty acid profiles may aggravate acne through insulin, IGF-1, and inflammatory pathways. However, findings across studies remain inconsistent. This systematic review and meta-analysis aimed to evaluate the associations between dietary glycemic load, glycemic index, dairy intake, and fatty acid composition with acne disorders. Methods: Following PRISMA 2020 guidelines, PubMed, EMBASE, and Scopus were systematically searched to September 2025. Eligible human studies assessing quantitative relationships between these dietary exposures and acne risk or severity were included. Random-effects meta-analyses were performed using the Hartung–Knapp–Sidik–Jonkman method, with effect sizes expressed as standardized mean differences (SMD) or risk ratios (RR). Result: Five studies encompassing 716 participants (426 acne, 290 controls) met the inclusion criteria. Pooled estimates indicated no significant associations for glycemic load (SMD = 0.09; 95% CI −0.30 to 0.49), glycemic index (SMD = 0.09; 95% CI −0.30 to 0.49), fatty acids/adiponectin (SMD = 0.11; 95% CI −0.74 to 0.97), or dairy consumption (RR = 1.04; 95% CI 0.25 to 4.25). Heterogeneity ranged from moderate to high (I² = 65–90%). Certainty of evidence was moderate for glycemic and dairy outcomes, and low for fatty acids. Conclusions: No significant pooled associations were observed between dietary glycemic load, dairy intake, or fatty acids and acne risk. Despite biological plausibility linking diet to acne via hormonal and inflammatory mechanisms, evidence remains inconsistent. Larger, controlled trials are warranted to define the role of nutritional interventions in acne management.
Co-Authors Amalia, Shania Rizky Hartanto, Ericko Istikanto, Ferdian Harum Limanda, Claudia Felicia Mathlubaa, Asya Musyayyadah, Musyayyadah Nabila, Yusra Nurfadhila, Melinda Putri, Syafira Ayudiah Syah Sianturi, Efry Theresia sisca Tutik Ernawati