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All Journal Medicinus : Jurnal Kedokteran Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Indonesian Journal of Global Health research Bali Dermatology Venereology and Aesthetic Journal
Limanda, Claudia Felicia
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health

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FACTORS AFFECTING MEDICAL STUDENTS’ STRESS DURING COVID-19 PANDEMIC: A CROSS-SECTIONAL STUDY Limanda, Claudia Felicia; Purnawati, Susy; Adiputra, Luh Made Indah Sri Handari; Tirtayasa, Ketut
Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Vol 12, No 1 (2023): Maret
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpki.77961

Abstract

Background: Since the emergence of COVID-19 in 2019, Indonesia’s COVID-19 Task Force has implemented distance or online learning in educational sectors, especially in Java and Bali. In its implementation, a certain number of medical students developed a tendency to prefer online learning compared to face-to-face learning without completely understanding its risks. Other factors such as financial barriers, social isolation, limitation of physical activity, change of diet, and anxiety-prone tendencies in COVID-19 pandemic, not much further research has been carried out. This study aims to determine whether medical students’ stress can be aggravated by several factors, namely online learning, financial barriers, social isolation, limitation of physical activity, change of diet, and anxiety-prone tendencies in order to obtain information whether online learning can be applied, even when the pandemic is over.Methods: Research design used a quantitative approach. Data collection was performed through online questionnaires distributed to 238 medical students selected using simplified random sampling. Data was analysed descriptively and inferentially. Inferential analysis used T-Test and ANOVA Test.Results: Online learning, financial barriers, social isolation, limitation of physical activity, change of diet, and anxiety-prone tendencies independently and cumulatively elevate medical students’ stress. Cumulatively, independent factors mentioned above have 85% effect in aggravating of medical students’ stress.Conclusion: Online learning application has to be reconsidered due to additional stress implicated to medical students. In addition, financial barriers, social isolation, limitation of physical activity, change of diet, and anxiety-prone tendencies are important factors in aggravating medical students’ stress.
Effect of Chicken Bile Application on Scar Healing Process limanda, Claudia Felicia; Intizam, Marwa Humaira; Jusuf, Pierre Joshua; Tanujaya, Monica Aprilia; Rusyati, Luh Made Mas
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 6, Issue 1 (June 2023)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/6kq9ke38

Abstract

Type of scars varies from mild fine line scars to abnormal scars which treatment will differ according to its type, site, symptoms, and severity. Scars have a great impact of human life, namely physically, aesthetically, psychologically, and socially that make choosing the right treatment very important. Treatment for scars can be done conventionally in health care facilities and traditionally. Chinese traditional medicine has been known to have a major role in scar treatment. One of the examples is the use of chicken bile. "Chicken bile", "Chicken bile effect", "Wounds", and "Wound healing process" were the keywords applied to scientific online databases. Wound healing is composed of three initial stages, such as inflammatory, proliferative, and remodeling stage. Chicken bile is known to have a low but strong bilirubin level with little biliverdin. These agents can serve as antipyretic, antioxidant, anti-inflammatory, and anti-atherogenic that can aide wound healing. Bile also supports protein metabolism, fat metabolism, energy production, and synthesis of glycogen. Most importantly, bile contains matrix metalloproteinases (MMPs) that function to degrade type IV collagen which have an important role in wound reepithelization process, altering wound matrix, enabling cell to migrate, and tissue remodeling. Thus, it is certain that MMPs are essential in wound healing.
Role of secretomes in chronic wound treatment: a review Limanda, Claudia Felicia; Intizam, Marwa Humaira; Augustin, Dara Cynthia
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 7, Issue 2 (July 2024)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/balidervenaesthj.v7i2.98

Abstract

Living with a chronic wound may prove to be devastating to patients both physically and psychologically. Wound increases economic and society burden due to low healing rate, prolonged hospital treatment, and increased epidemiology worldwide. Therefore, application wound treatment modalities are necessary for patient recovery. However, each modality has their own advantage and limitation. As a newly-founded modality, secretome, which originated from Mesenchymal stem cells (MSCs) plays an important role in chronic wound healing due to its ability in promoting tissue regeneration and self-renewal that supports cell proliferation and migration. However, different therapeutic potentials can arise according to each source of stem cells. This review highlights the importance of secretome as a modality in treating chronic wounds. Secretome types, stem cell origin, and results when applied in vitro and in vivo will also be comprehensively reviewed.
Effectiveness and tolerability of bakuchiol (Psolarea corylifolia) as a dermal anti-aging modality: A systematic review on skin wellness and harmony Limanda, Claudia Felicia; Els, Vanessa; Hernowo, Elliana Freya; Winaya, Ketut Kwartantaya
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 8, Issue 1 (2025)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/balidervenaesthj.v8i1.116

Abstract

Skin aging is a natural phenomenon caused by a decline in collagen production that leads to skin thinning, dry and pale skin, wrinkles, and sagging. Skin aging may not contribute to the mortality rate. However, people tend to connect their symbol of inner self to external appearance. Therefore, psychosocial effects such as social anxiety, low self-esteem, and low satisfaction in life will affect their personal and social life. Anti-aging procedures focus on the prevention of damage, replacement of tissues, and skin rejuvenation. Bakuchiol (Psolarea corylifolia) is a novel anti-aging product with antioxidant, anti-inflammatory, and anti-aging properties that is deemed effective and tolerable in skin rejuvenation. This comprehensive review aims to further examine the effectiveness and tolerability of bakuchiol based on previous studies in order to provide new insights into delaying skin aging. A comprehensive literature search was conducted to assess the effectiveness and tolerability of bakuchiol as a dermal anti-aging modality from search engines, PubMed, Google Scholar, CORE, Science Direct, and Cochrane using search terms (“Bakuchiol” OR “Psolarea corylifolia”) AND (“Dermal Aging” OR “Skin Aging”). Bakuchiol proved to have anti-inflammatory and antioxidant properties to maintain youthfulness and skin appearance. Regarding tolerability, bakuchiol has fewer side effects compared to other commonly used modalities. Therefore, bakuchiol (Psolarea corylifolia) is an effective and tolerable modality in the treatment of aging skin.
Role of Vitamin D in the Treatment of Atopic Dermatitis Limanda, Claudia Felicia; Gabriella, Gabriella; Bernadetta, Elvira; Hakim, Jackson; Tansuri, Verika Christabela
Indonesian Journal of Global Health Research Vol 6 No 4 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i4.3195

Abstract

Atopic dermatitis (AD) is a chronic and recurrent inflammatory condition that affects patients' quality of life. One alternative that has an anti-inflammatory effect on AD is vitamin D (25-hydroxyvitamin D (25(OH)D). Although the main treatment for AD uses drugs such as corticosteroids or immunosuppressants, the side effects caused are quite high. Therefore, the aim of this review This literature aims to find out more about the effectiveness of vitamin D against AD, so that it can be an alternative treatment option. Objective: To determine the role of vitamin D in the treatment of atopic dermatitis. Method: The research took database sources from Pubmed, Google Scholar, Science Direct, and Cochrane from 2014-2023 which were then selected based on the inclusion and exclusion criteria that had been created. A total of 17972 articles were found using the keywords ("Vitamin D" OR "Calciferol" OR "Calcitriol") AND "Atopic Dermatitis" AND ("Role" OR "Function") which then after screening, 16 articles were taken for this literature review. Results: AD is an inflammatory condition that is influenced by various factors. The severity of this disease can be assessed using SCORAD or EASI. AD patients generally have lower serum vitamin D levels and decreased SCORAD index. However, vitamin D supplementation in AD treatment varies according to each country and geographic region. Conclusions: Various studies have been conducted to review the effects of vitamin D supplementation on AD, but not all of them show significant effects. This is influenced by many factors, especially age, dosage, preparation, country and geographical area. So more in-depth research is needed on this matter.
The Role of Glycemic Load, Dairy, and Fatty Acids in Acne Disorders: A Systematic Review and Meta-Analysis Limanda, Claudia Felicia; Mathlubaa, Asya; Istikanto, Ferdian Harum; Sisca; Nabila, Yusra; Amalia, Shania Rizky; Putri, Syafira Ayudiah Syah; Ilmiani, Tasya Khalis; Hartanto, Ericko; Nurfadhila, Melinda
Medicinus Vol. 15 No. 1 (2025): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v15i1.10771

Abstract

Background: Modern dietary patterns characterized by high glycemic load, dairy consumption, and imbalanced fatty acid profiles may aggravate acne through insulin, IGF-1, and inflammatory pathways. However, findings across studies remain inconsistent. This systematic review and meta-analysis aimed to evaluate the associations between dietary glycemic load, glycemic index, dairy intake, and fatty acid composition with acne disorders. Methods: Following PRISMA 2020 guidelines, PubMed, EMBASE, and Scopus were systematically searched to September 2025. Eligible human studies assessing quantitative relationships between these dietary exposures and acne risk or severity were included. Random-effects meta-analyses were performed using the Hartung–Knapp–Sidik–Jonkman method, with effect sizes expressed as standardized mean differences (SMD) or risk ratios (RR). Result: Five studies encompassing 716 participants (426 acne, 290 controls) met the inclusion criteria. Pooled estimates indicated no significant associations for glycemic load (SMD = 0.09; 95% CI −0.30 to 0.49), glycemic index (SMD = 0.09; 95% CI −0.30 to 0.49), fatty acids/adiponectin (SMD = 0.11; 95% CI −0.74 to 0.97), or dairy consumption (RR = 1.04; 95% CI 0.25 to 4.25). Heterogeneity ranged from moderate to high (I² = 65–90%). Certainty of evidence was moderate for glycemic and dairy outcomes, and low for fatty acids. Conclusions: No significant pooled associations were observed between dietary glycemic load, dairy intake, or fatty acids and acne risk. Despite biological plausibility linking diet to acne via hormonal and inflammatory mechanisms, evidence remains inconsistent. Larger, controlled trials are warranted to define the role of nutritional interventions in acne management.
Co-Authors Amalia, Shania Rizky Augustin, Dara Cynthia Bernadetta, Elvira Els, Vanessa Gabriella, Gabriella Hakim, Jackson Hartanto, Ericko Hernowo, Elliana Freya Ilmiani, Tasya Khalis Intizam, Marwa Humaira Istikanto, Ferdian Harum Jusuf, Pierre Joshua Ketut Tirtayasa LUH MADE INDAH SRI HANDARI ADIPUTRA Luh Made Mas Rusyati Mathlubaa, Asya Nabila, Yusra Nurfadhila, Melinda Putri, Syafira Ayudiah Syah sisca Susy Purnawati Tansuri, Verika Christabela Tanujaya, Monica Aprilia Winaya, Ketut Kwartantaya