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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan MEDIC MEdical Dedication Electronic Journal Scientific of Environmental Health And Diseases
Ekaputri, Tia Wida
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Education Environmental Science Health Professions Medicine & Pharmacology Nursing Physics Public Health

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AT Genotype of FTO rs9939609 Enhances Risk for Central Obesity Under Obesogenic Lifestyle Maharani, Citra; Puspasari, Anggelia; Enis, Rina Nofri; Ekaputri, Tia Wida; Shafira, Nyimas Natasha Ayu
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 13 No. 1 (2025): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v13i1.38811

Abstract

Background: Central obesity is a major risk factor for cardiovascular diseases, influenced by both genetic and lifestyle factors. The rs9939609 variant of Fat Mass and Obesity-Associated (FTO) gene has been associated with increased risk of central obesity, potentially modulated by dietary intake and physical activity. Objective: This study aimed to investigate the association between the FTO rs9939609 variant and central obesity, and its interaction with dietary intake and physical activity among adults in Jambi, Indonesia. Method: A cross-sectional study was conducted on 175 adults. Central obesity was defined using NCEP ATP III criteria. Dietary intake and physical activity were assessed using 24-hour food recall and the IPAQ, respectively. Genotyping was performed using the Tetra ARMS-PCR. Bivariate analysis was used to assess associations. Results: Individuals with the AT genotype had a significantly increased risk of central obesity (OR= 3.29; 95% CI: 1.30–8.35; p= 0.01). Under the dominant model (AAAT), the association remained significant (OR= 2.90; 95% CI: 1.17-7.16; p= 0.02). The risk was higher among individuals with high caloric intake (OR= 4.64) and low to moderate physical activity (OR= 4.77). Conclusion: The FTO rs9939609 variant is associated with increased central obesity risk, and in the presence of obesogenic lifestyle factors.
Training Mothers on Complementary Feeding Preparation and Toddler Growth Screening at Olak Kemang Health Center harahap, huntari; Aurora, Wahyu Indah Dewi; Hanina, Hanina; Ekaputri, Tia Wida; Ayudia, Esa Indah
Scientific Of Environmental Health and Diseases (e-SEHAD) Vol. 5 No. 1 (2025): Electronic Journal Scientific of Environmental Health And Diseases
Publisher : LPPM Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/e-sehad.v5i2.37910

Abstract

Background: Proper complementary feeding is crucial for optimal child growth and development. However, many mothers lack knowledge about the correct preparation, timing, and nutritional composition of complementary feeding, increasing the risk of malnutrition and stunting in toddlers. This community service program aimed to enhance maternal knowledge on complementary feeding and conduct growth and development screenings for toddlers. Method: The program was conducted at Olak Kemang Health Center and involved 15 mothers and their children. The intervention included hands-on training led by nutrition experts on the proper preparation and nutritional composition of complementary feeding. Additionally, toddlers underwent growth and development assessments using anthropometric measurements and the Pre-Screening Questionnaire for Development (KPSP). Result: The majority of toddlers (73.33%) had normal nutritional status, while 13.33% were underweight and 13.33% were overweight. Growth and development screening showed that 93.3% of toddlers demonstrated normal development, whereas 6.67% had developmental delays. The training significantly improved mothers' knowledge of complementary feeding preparation. Conclusion: Regular educational programs are essential to improve maternal knowledge on complementary feeding and enhance early childhood growth monitoring. These efforts can help reduce the risk of malnutrition and stunting among toddlers.
OPTIMIZING MATERNAL AND CHILD HEALTH: ENHANCING PUBLIC AWARENESS OF TORCH INFECTIONS DURING PREGNANCY Ekaputri, Tia Wida; Enis, Rina Nofri; Tarawifa, Susan; Harahap, Huntari; Syauqy, Ahmad; Perkasa, Tengku Arief Buana
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 8 No. 1 (2025): MEDIC. Medical dedication
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

TORCH infections (Toxoplasmosis, Rubella, Cytomegalovirus, Herpes simplex) pose significant risks during pregnancy, contributing to congenital abnormalities and adverse neonatal outcomes. In Indonesia, limited public awareness and inadequate preventive practices exacerbate these risks. This community service initiative aimed to enhance knowledge about TORCH infections among reproductive-aged women through a hybrid educational seminar. Conducted in collaboration with Peduli TORCH, the program utilized the "5P Framework" (Pathogen Awareness, Prenatal Screening, Pathogen Management, Postnatal Monitoring, Preventive Practices) to deliver evidence-based strategies. A total of 54 participants (87% female, 61.1% from Jambi Province) attended the seminar, combining in-person and virtual engagement. Pre- and post-tests assessed knowledge improvement, revealing a statistically significant median score increase from 70.0 to 100.0 (p<0.001, Wilcoxon test). Participants reported high satisfaction with the seminar’s content, interactive format, and accessibility, though logistical refinements were suggested for future iterations. The initiative successfully bridged knowledge gaps, emphasizing the importance of early screening, vaccination, and hygiene practices. By empowering women and leveraging community engagement, this program highlights the potential of targeted educational interventions to reduce TORCH-related morbidity and improve maternal-child health outcomes. Culturally adapted, hybrid approaches demonstrate promise for scalable public health strategies in low-resource settings.
The Effect of Ethanol Extract of Senggani Leaves (Melastoma malabathricum) on Reducing Paw Edema in Rats Induced By Carrageenan Ekaputri, Tia Wida; Dewi, Hasna; Wulandari, Putri Sari; Enis, Rina Nofri
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 13 No. 1 (2025): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v13i1.38925

Abstract

Background: The extract of senggani leaves (Melastoma malabathricum) has attracted attention as a potential anti-inflammatory agent due to its diverse phytochemical content, including flavonoids, tannins, and other polyphenols, which have been shown to possess antioxidant and anti-inflammatory activities in several previous studies. This study aims to determine the difference in the percentage of inflammation inhibition of paw edema in rats induced by carrageenan through the administration of senggani leaves extract. Methods: In this study, 24 rats were divided into 4 groups. Negative control group was given Na-CMC 0.5%, Positive control group was given Na-diclofenac 50 mg/kg BW. Two dosage groups were given senggani extract solution at 250 and 500 mg/kg BW. Carrageenan is used to induce local inflammation by injecting a 2% carrageenan solution in physiological NaCl subcutaneously into the subplantar region of all test animal groups to elicit an edema response. Paw thickness is measured using calipers at hour 0 before inflammation induction, followed by measurements at hours 1, 2, 3, 4, and 5. Results: The peak inhibitory effect (62.10% and 60.41%) for both doses of senggani extract was observed at the 3rd hour, suggesting a rapid onset of action. At the higher dose (500 mg/kg BW), senggani extract exhibited comparable or even slightly superior inhibitory effects to Na-diclofenac. Conclusion: Senggani extract has potential as a natural anti-edema agent. Further research is needed to explore its mechanism of action and optimize its therapeutic use.
Co-Authors Ahmad Syauqy Anggelia Puspasari Citra Maharani dewi, hasna Esa Indah Ayu, Esa Indah Hanina, Hanina Huntari Harahap Nyimas Natasha Ayu Shafira Putri Sari Wulandari Rina Nofri Enis Tarawifa, Susan Tengku Arief Buana Perkasa Wahyu Indah Dewi Aurora