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All Journal Indonesian Journal of Cancer Chemoprevention JURNAL ILMIAH GLOBAL EDUCATION Indonesian Journal of Health Science
Octaviani, Putri
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Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Public Health Veterinary Other

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Health system transformation in Indonesia: Implementation and challenges of six policy pillars El-Tsana, Ashfiya Vi'aqila; Alvianty, Rizka Ayu; Octaviani, Putri; Syahidah, Raisha; Wasir, Riswandy
Indonesian Journal of Health Science Vol 5 No 3 (2025)
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/ijhs.v5i3.1548

Abstract

Indonesia’s health system transformation is structured around six strategic pillars: primary care, referral services, system resilience, financing, human resources, and health technology. This study aims to assess the implementation progress and challenges associated with these pillars. A literature review was conducted using national and international databases (Google Scholar and ScienceDirect), focusing on peer-reviewed articles published between 2016 and 2025. Four studies were selected based on inclusion criteria that emphasized relevance to Indonesia’s health system transformation agenda. The review identified key challenges, including limited digital infrastructure, uneven distribution of the health workforce, rigid financing mechanisms, particularly within Public Service Agency (BLU) institutions and weak intersectoral coordination. Many facilities remain unprepared for digital integration, particularly the implementation of Electronic Medical Records (EMR). Although some improvements have been observed, structural barriers continue to hinder the overall progress. Strengthening digital readiness, enhancing workforce capacity, adopting more flexible budgeting mechanisms, and improving coordination, especially through platforms such as SATUSEHAT are recommended as strategic responses. However, this study has several limitations, such as the limited availability of articles that cover all six pillars comprehensively and most of the studies used emphasize legal and administrative aspects rather than specific analysis in the health sector. These limitations limit the generalization of the findings. These findings are expected to inform more adaptive and equitable health policy reforms in Indonesia.
Molecular Docking and Molecular Dynamic Simulation on the Interaction of Saffron’s Active Compunds with HER-2 Protein Adelina, Rosa; Maharani, Dila Aulia; Octaviani, Putri; Putra, Sendi Handika
Indonesian Journal of Cancer Chemoprevention Vol 14, No 2 (2023)
Publisher : Indonesian Society for Cancer Chemoprevention

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14499/indonesianjcanchemoprev14iss2pp117-127

Abstract

Human epidermal growth factor receptor-2 (HER-2) is an essential oncogene in breast cancer. HER-2 causes 25% of breast cancer, and this type of cancer tends to grow and spread faster than others but had a good response to HER-2 targeted therapy. This study aims to analyze chemical compounds in saffron plants (Crocus sativus) that potential to breast anticancer activity by inhibiting HER-2 receptor (PDB ID: 3RCD). The study employed in silico research such as molecular docking using AutoDock Tools software, and visualization with Biovia Discovery Studio. In addition, molecular dynamic simulation was conducted using GROMACS software, with visualization performed using Grace. The molecular docking results showed that Crocetin has a lower binding energy value of -8.37 kcal/mol compared to Herceptin, which is -7.11 kcal/mol and the lowest energy among Saffron bioactive compounds. These results indicated that the affinity of Crocetin in binding to HER-2 receptor is better than Herceptin. The molecular interactions were hydrogen, hydrophobic, electrostatic, and unfavorable bonds. The MD results showed that the RMSD value meets the 0.2-0.5 nm stability requirements. According to the data analysis, Herceptin appears to have a more stable RMSF value when compares to Crocetin. The Rg graph of both complexes showed stability until the end of the simulation. The H-bond results show that the Herceptin complex has more hydrogen bonds than the Crocetin complex. These results showed that the chemical components of saffron plants have the potential as breast anticancers by inhibiting the HER-2 receptor.Keywords: anticancer, Crocus sativus, HER-2 receptor, molecular docking, molecular dynamic.
Perencanaan SDM kesehatan: Mewujudkan kebutuhan tenaga kesehatan melalui strategi yang efektif Octaviani, Putri; Fitri, Tasya Ariani; Kurnia, Inara Perdana; Wasir, Riswandy; Arbitera, Cahya
Indonesian Journal of Health Science Vol 4 No 6s (2024): Mewujudkan Indonesia Sehat: Transformasi Sistem Kesehatan di Era Baru
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/ijhs.v4i6s.1275

Abstract

Perencanaan Sumber Daya Manusia (SDM) kesehatan adalah hal yang penting dalam mewujudkan pelayanan kesehatan yang optimal dan merata di Indonesia. Artikel ini mengkaji analisis kebutuhan, distribusim serta beban kerja tenaga kesehatan sebagai bagian dari strategi perencanaan yang efektif. Dengan menggunakan metode studi literatur, penelitian ini menyoroti ketimpangan distribusi tenaga kesehatan, khususnya di daerah yang sulit dijangkau, serta tingginya beban kerja yang dapat menurunkan kualitas pelayanan. Metode seperti Workload Indicators of Staffing Needs (WISN) dan Analisis Beban Kerja (ABK) digunakan untuk mendukung perencanaan berbasis data. Hal yang direkomendasikan meliputi pemberian insentif bagi tenaga kesehatan di daerah tertinggal, pelatihan untuk meningkatkan keterampilan, serta pemanfaatan tekonologi dalam manajemen adminitrasi. Selain itu, kolaborasi lintas sektor antara pemerintah, institusi pendidikan, dan sektor swasta juga diperlukan untuk memastikan keberlanjutan tenaga kesehatan yang berkualitas. Dengan perencanaan yang berbasis data dan pendekatan holistic, sistem kesehatan di Indonesia dapat mengatasi ketimpangan, meningkatkan efisiensi, serta memberikan akses pelayanan yang lebih baik bagi seluruh masyarakat. Pendekatan ini diharapkan menjadi Solusi untuk menciptakan sistem kesehatan yang Tangguh dan berkelanjutan.
Organic Waste Reduction Strategy through Maggot Cultivation and Composting In Kota Pari Village Purba, Renti Eva; Humairoh, Syahfitri; Angginta, Teguh; Akbar, Muhammad Fazlan; Octaviani, Putri
Jurnal Ilmiah Global Education Vol. 6 No. 4 (2025): JURNAL ILMIAH GLOBAL EDUCATION
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/jige.v6i4.4397

Abstract

Kota Pari Village is a developing village or can be categorized as an independent village. Waste is one of the problems experienced by this village. Waste generation in this village mostly comes from household waste which is a type of organic waste and the low level of public knowledge about waste management, especially organic waste, further exacerbates the situation in Kota Pari Village so that the waste problem becomes more complex and needs to be addressed immediately. The purpose of this activity is to carry out waste management through the use of insects (maggot cultivation) and microorganisms (composting) to reduce organic waste generation. This activity was carried out on June 1, 2024 until October 30, 2024. The methods used were identifying problems, conducting socialization, preparing containers and materials and training. The community that participated in this program showed a very good reaction and participated in all series of activities actively. The cultivation of maggot and composting of organic waste that has been carried out can foster community awareness in managing organic waste properly and can be a solution and strategy in reducing organic waste in the village environment.
Co-Authors Akbar, Muhammad Fazlan Alvianty, Rizka Ayu Angginta, Teguh Arbitera, Cahya El-Tsana, Ashfiya Vi'aqila Fitri, Tasya Ariani Humairoh, Syahfitri Kurnia, Inara Perdana Maharani, Dila Aulia Purba, Renti Eva Putra, Sendi Handika Riswandy Wasir Rosa Adelina Syahidah, Raisha