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All Journal Majalah Kedokteran Bandung Sari Pediatri Universa Medicina jurnal ilmu keolahragaan Muhammadiyah Medical Journal
Handoko, Willy
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Humanities Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Patofisiologi Jantung pada Latihan Fisik Berat Handoko, Willy; Natalia, Diana
Jurnal Ilmu Keolahragaan Vol 7, No 1 (2024): JURNAL ILMU KEOLAHRAGAAN
Publisher : Universitas Tanjungpura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/jilo.v7i1.77959

Abstract

Latihan fisik yang rutin dapat menyebabkan beberapa perubahan fisiologis yang menguntungkan pada tubuh dan efektif dalam pencegahan dan bersifat terapeutik pada berbagai jenis penyakit kronik, seperti penyakit jantung koroner, hipertensi, gagal jantung, obesitas, depresi dan diabetes melitus. Meskipun bermanfaat, latihan fisik, sama halnya dengan obat–obatan farmasi memiliki batas maksimum. Latihan fisik yang dilakukan secara berlebihan akan mempunyai dampak negatif (seperti trauma musculoskeletal atau stres kardiovaskuler) yang lebih besar daripada manfaatnya
THE EFFECT OF SINGLE- AND REPEATED- EXCESSIVE SWIMMING EXERCISE ON KIDNEY HISTOPATHOLOGY OF MALE RATS WISTAR STRAIN (Rattus norvegicus) Tripani, Wenni Juniarni; Ilmiawan, Muhammad In’am; Handoko, Willy
Muhammadiyah Medical Journal Vol 1, No 1 (2020): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (778.278 KB) | DOI: 10.24853/mmj.1.1.33-42

Abstract

Background: Physical exercise aims to improve or maintain physical fitness. However, excessive physical exercise may cause increase of oxidative stress which leads to cellular injury, including in the proximal tubules of kidney. This research aims to find out the effect of single- and repeated- excessive swimming exercise to the kidney histopathology of male wistar rats (Rattus norvegicus). Methods: This research was an experimental study with complete random and post test only control group design. Twenty seven male wistar rats were divided into three treatment groups: control group, single- excessive swimming exercise group (45 minutes for one day), and repeated- excessive swimming exercise group (45 minutes/day for seven days). In the end of the treatment, the kidney of the rats were taken to be analyzed by using hematoxylin-eosin stain. The mean of proximal tubules injury of kidneys were counted by two observers using blinded method. Data were analyzed by using one way anova test. Result: The analysis showed there was a significant difference in the mean percentage of proximal tubules injury between control group and single swimming group as well as the repeated swimming group (Anova p=0,000), also there was significant difference between the treatment groups (p=0,020). The highest average of proximal tubules injury was in the single swimming group. Conclusion: Single- and repeated- excessive swimming exercise causes the proximal tubules injury of kidney.
Threat of zoonotic malaria and strategy to overcome in Kalimantan (Indonesian Borneo) bordering Malaysian Borneo Natalia, Diana; Handoko, Willy; Rahmayanti, Sari; Wahyudi, Tri; Abdul Rashid, Ayu Akida; Divis, Paul Cliff Simon
Universa Medicina Vol. 44 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2025.v44.208-218

Abstract

Indonesia aims to eradicate malaria by 2030. Indonesia has the second highest disease burden in the WHO South-East Asia region, after India, accounting for 9% of all malaria cases in 2024. Malaria cases have dropped dramatically due to national strategic plans and programs, and the Indonesian Ministry of Health has certified several districts as malaria-free zones. Malaria cases in Kalimantan (Indonesian Borneo), have declined during the last two decades. Nearly all regencies within these provinces have been declared as having low malaria endemic status (API<1 per 1000 people), except for one regency in East Kalimantan Province, which showed a high endemicity level (API>5 per 1000 people). This reduced incidence, however, contrasts sharply with the zoonotic infection caused by the simian parasite Plasmodium knowlesi, which is prevalent in Malaysian Borneo. Only a few cases of P. knowlesi infection have been reported in South and Central Kalimantan Province since 2010. This difference between Kalimantan, Indonesia and Borneo, Malaysia appears contradictory given that both regions have a similar epidemiological risk of zoonotic malaria infection and share the same natural habitat. The references were tracked using various databases, such as Google Scholar, PubMed (MEDLINE) and other sources (Google engine and manual searching using a reference list). This review’s objective was to describe current malaria and zoonotic malaria, mosquito vector prevalence, and the available data from case reports along the Kalimantan border in Indonesia during the malaria elimination phase, compared with malaria distribution in the neighbouring country, Malaysian Borneo.
Pengaruh Pengajaran dengan Media Video terhadap Pengetahuan Mahasiswa tentang Pengukuran Antropometri Bayi Linati, Raudina Dwita; Handoko, Willy; Andriani, Rini
Sari Pediatri Vol 27, No 1 (2025)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp27.1.2025.51-7

Abstract

Latar belakang. Antropometri adalah salah satu metode dalam penilaian status nutrisi pada anak maupun dewasa. Malnutrisi menjadi salah satu masalah kesehatan masyarakat di Indonesia terutama Kalimantan Barat dengan proporsi 19,58%. Saat pandemi COVID-19 dilaksanakan pembelajaran jarak jauh, sehingga diperlukan suatu media yang inovatif sebagai upaya pembelajaran mahasiswa mengenai pengukuran antropometri bayi. Tujuan. Mengetahui perubahan pengetahuan mahasiswa mengenai pengukuran antropometri bayi setelah pengajaran dengan media video.Metode. Penelitian menggunakan metode one group pretest-posttest. Sampel penelitian diambil secara total sampling dengan jumlah 100 mahasiswa Program Studi Kedokteran Universitas Tanjungpura angkatan 2021. Analisis bivariat menggunakan uji t berpasangan.Hasil. Proporsi mahasiswa dengan tingkat pengetahuan “sangat baik” meningkat dari 29% sebelum intervensi menjadi 72% setelah intervensi, menunjukkan adanya peningkatan yang signifikan setelah pemberian media video. Penggunaan media pembelajaran berbasis video terbukti efektif dalam meningkatkan pengetahuan siswa mengenai pengukuran antropometri pada bayi.Kesimpulan. Pengajaran dengan media video secara signifikan meningkatkan pengetahuan mahasiswa kedokteran mengenai pengukuran antropometri bayi.
Effect of Spinal Anesthesia on Blood Pressure During Cesarean Section in Private Indonesian Hospital Nanmi, Nassya Putri; Lailly, Husnul; Armyanti, Ita; Novitarini, Poppy; Handoko, Willy
Majalah Kedokteran Bandung Vol 57, No 2 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.4104

Abstract

The 2018 Indonesian Basic Health Research Data presented an increase in the number of cesarean sections from the previous years, with an increase of 17.6%. In Anugerah Bunda Khatulistiwa Hospital, a private hospital in Pontianak, Indonesia, cesarean section was performed in 689 and 641 cases in 2021 and 2022, respectively. This trend highlights the importance of understanding the anesthesia methods used during this procedure, including spinal anesthesia. Despite the common use of this type of anesthesia, spinal anesthesia an cause changes in the maternal blood pressure. This study aimed to determine the effect of spinal anesthesia on patients’ blood pressure during cesarean section. This retrospective observational analytical study was conducted at the Anugerah Bunda Khatulistiwa Hospital Pontianak, Indonesia, from May 2023 to January 2024. Medical records were selected from 246 patients using consecutive sampling method. Most patients aged between 27 and 29 years, with 207 were in the productive age group (20-35 years). The mean weight was 72.77 kg (±10.43) and the mean height was 156.70 cm (±5.85). The majority were overweight based on the BMI score (n=111), and the spinal anesthesia dose used was 15 mg bupivacaine. The Friendman test on the systolic and diastolic blood pressures before and after anesthesia to determine the effect of spinal anesthesia on blood pressure. The results showed a p-value of 0.000 (p<0.05) for both systolic and diastolic observations. This indicates that spinal anesthesia influences the blood pressure of patients undergoing cesarean sections under spinal anesthesia.
Co-Authors Abdul Rashid, Ayu Akida Armyanti, Ita Diana Natalia Divis, Paul Cliff Simon Erwin Setiawan, Erwin Ilmiawan, Muhammad In’am Lailly, Husnul Linati, Raudina Dwita Nanmi, Nassya Putri Novitarini, Poppy Rini Andriani Sari Rahmayanti Tri Wahyudi Tripani, Wenni Juniarni