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Bahraen, Raehanul
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology

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Penentuan Cut-off Indeks Diskriminasi Diagnosis Pada Anemia Defisiensi Besi Dan Beta Thalassemia Minor Bahraen, Raehanul
Jurnal Kedokteran Vol 10 No 1 (2021): volume 10 nomor 1 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i1.489

Abstract

Background: Beta thalassemia minor and iron deficiency anemia were most common cases of mild hypochoromic microcytic anemia. The differential diagnosis between beta thalassemia minor and iron deficiency anemia was important to avoid unnecessary iron therapy and to avoid false beta thalassemia minor diagnosis. We need valid and easy formula to make differentiate between them. It can be applied by using the red blood cell index (RBC) in the basic hematology examination. Methods: This study was a cross-sectional study with 30 samples of ADB and 30 samples of BTM in DR. Sarjito Hospital, Yogyakarta. Iron deficiency anemia was defined as microcytic anemia with mean corpuscular volume (MCV) <80 fL with ferritin levels <12 ?g / dl and hemoglobin A2> 3.5%. Beta thalassemia minor was defined as microcytosis with hemoglobin A2 ? 3.5%. We compared ten different discrimination formulas with seven red cell parameters. The calculation includes the cut-off value, sensitivity, specificity, positive predictive value , negative predictive value, and evaluation of the receiver operative characteristic (ROC) curve. Results: This study showed that Green & King, RDW index and Sirdah formula have the largest area under curve with value respectively 0.995; 0.992 and 0.0909 dan cut-off value <84.7; <240,7 and <40,12. Conclusion: The Green & King, RDW index and Sirdah formila were the highest formula to differentiate Beta thalassemia minor and iron deficiency anemia in DR. Sardjito hospital, Yogyakarta.
The Effect of Knowledge Level on Anemia among Adolescent Girls in Coastal West Lombok Rachman, Amanda Azkiyah; Lestarini, Ima Arum; Bahraen, Raehanul
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10282

Abstract

Hemoglobin levels below 12 g/dL, or anemia, continue to be a serious health issue in developing nations like Indonesia. Teenage girls in coastal areas are particularly at risk. Although research in West Lombok is still in its infancy, knowledge is thought to be the first step in prevention. The aim of this study is to analyze the effect of knowledge level on anemia among adolescent girls in coastal West Lombok. This categorical analytic observational study applied a cross-sectional design, chosen for its efficiency in assessing associations at a single point in time. Purposive sampling recruited 101 respondents who met inclusion criteria (female, aged 15–19, residing in coastal West Lombok, willing to participate). Exclusion criteria included chronic illness or refusal of blood testing. Data were obtained using a validated online questionnaire and hemoglobin measurement. Statistical analysis employed Chi-square test with SPSS version 25.0. The result indicated no significant association was found between knowledge and anemia (p=0.599). However, girls with low knowledge had 1.3 times higher risk of anemia (OR=1.295; 95% CI: 0.493–3.399), suggesting other contributing factors such as nutrition and socioeconomic conditions. In conclusion, knowledge alone does not significantly affect anemia incidence. Integrated education, nutritional interventions, and routine iron supplementation are recommended, with further studies needed.
The Difference in Total Cholesterol Levels Between Male Smokers and Non-Smokers Aged 20-50 Years Humam, Anang Muh. Naufal; Bahraen, Raehanul; Suryani, Dini
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7711

Abstract

Indonesia is ranked third in the world after India and China with the largest number of smokers. LDL, triglyceride, total cholesterol, and HDL levels can all rise and fall due to smoking. While HDL serves to prevent the formation of atherosclerosis, high LDL levels can increase the risk of atherosclerosis. POCT (Point of Care Testing) is one procedure to check total cholesterol levels. The purpose of this study was to determine the difference in total cholesterol levels of male smokers and non-smokers aged 20-50 years in the Kopang Health Center work area in 2023. This study used a cross-sectional approach. The sampling technique in this study was purposive sampling. The results of this study showed that 63.3% were light smokers, 36.7% were moderate smokers and no heavy smokers. A total of 66.7% of smokers had normal total cholesterol levels while 33.3% experienced increased levels. Non-smokers as many as 96.7% had normal total cholesterol levels and 3.3% experienced increased levels. The results of the Chi-square test showed a P value of 0.010, which means P <0.05, so there is a significant difference between the cholesterol levels of smokers and non-smokers. The conclusion is that total cholesterol levels are normal in smoker respondents and total cholesterol levels are high in non-smoker respondents. The recommendation from this study is the importance of reducing cigarette consumption, controlling cholesterol levels regularly, and maintaining a healthy lifestyle to prevent a significant decrease in HDL levels.
Gastric Lymphoma : A Literatur Review Pramudya, Rian; Alami, Fathimah Nur; Sesariana, Mayumi Agestia; Balqis, Ananda Amirah; Fidelia, Puspa Zalika; Yulianti, Nur Afni; Bahraen, Raehanul
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.7913

Abstract

Gastric lymphoma is the second most common finding in gastric malignancies worldwide. Gastric lymphoma is a lymphoproliferative disorder that originates in the stomach and encompasses various histological findings. In cases of gastric lymphoma, the most frequently diagnosed types are diffuse large B-cell lymphoma (DLBCL) and mucosa-associated lymphoid tissue (MALT) lymphoma. There is a known association between Helicobacter pylori infection and genetic mutations with the occurrence of gastrointestinal lymphoma. Treatment options for gastric lymphoma include observation, antibiotic therapy, radiation therapy, surgery, and chemotherapy. The therapy provided can be either monotherapy or a combination of treatments.
Co-Authors Alami, Fathimah Nur Balqis, Ananda Amirah Dini Suryani, Dini Fidelia, Puspa Zalika Humam, Anang Muh. Naufal Ima Arum Lestarini Pramudya, Rian Rachman, Amanda Azkiyah Sesariana, Mayumi Agestia Yulianti, Nur Afni