Claim Missing Document
Check
Articles

Found 4 Documents
Search

Uji Efek Inhibitorik Komponen Bioaktif Bawang Putih (Allium sativum) terhadap Lanosterol 14α-demethylase pada Candida albicans melalui Studi In Silico Ananda, Aditya Tri; Nuzula, Alsya Firdausi; Safitri, Devi Ayu
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 5, No 2 (2020): June 2020
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v5i2.2940

Abstract

Candida albicans is a unicellular fungi which causes candidiasis in human and livestock animals especially chicken. Candidiasis could reduce productivity significantly by early culling and causing a great deficit in the farm. Allium sativum or garlic is widely known as herbal which has an inhibitory effect in fungi’s growth. This research’s aim is to prove the effectivity of bioactive compound in Allium sativum to lanosterol 14α-demethylase which plays a role in ergosterol synthesis as a basic structure in fungi’s cell membrane. The ligand sheet retrieved from PubChem database and for the receptor in Protein Data Bank database. Molecular docking conducted by using Autodock Vina and then ligand-receptor complex is visualized with PyMOL and Ligplot+. From compounds that we have been analyzed, Gallic Acid has the most negative binding energy than other compounds have and it has the same amino acid residue with control. In conclusion of that, Gallic Acid in Allium sativum has potential as anti-candidiasis drug.
Detection of Escherichia coli Contamination using Most Probable Number (MPN) methods in Chicken Meats in Market of Surabaya Wardhana, Dhandy Koesoemo; Safitri, Devi Ayu; Annisa, Suwaibatul; Effendi, Mustofa Helmi; Harijani, Nenny
Jurnal Medik Veteriner Vol. 4 No. 1 (2021): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol4.iss1.2021.118-124

Abstract

Foodborne diseases are diseases transmitted through contaminated food and are one of the main public health problems. The bacteria that usually contaminates chicken meat is Escherichia coli. E. coli contamination in chicken meat can affect consumer health. Chicken meat processing and market conditions affect the level of bacteria contamination. This study aims to measure the contamination of E. coli bacteria in chicken meat in Surabaya's markets. The method which used to count and estimate the number of E. coli bacteria found in chicken meat in this study was Most Probable Number (MPN). The results showed 20 samples (33.3%) from 60 samples gave negative results. This indicated that only 20 samples of chicken meat were safe for consumption because the MPN value is <1 í— 101 CFU/g while the remaining 40 samples (66.7%) were not safe for consumption because the MPN value is> 1 í— 101 CFU/g. The standard of SNI 3924: 2009 concerning the minimum requirement for the amount of E. coli contamination in chicken meat is 1í—101 CFU/g so that the contamination of E. coli which found in chicken meat in Surabaya was high.
Descriptive Study of Learning Interest of Grade VIII Students of SMP Muhammadiyah 2 Tarakan City Safitri, Devi Ayu; Rahmi, Siti; Muhja, Zainal Abidin
Journal of Social Science and Economics (JOSSE) Volume 2, Issue 2, August 2025
Publisher : Asha Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70188/z0mwrr78

Abstract

This study aims to analyse the learning interests of grade VIII students at SMP Muhammadiyah 2 Tarakan City and the factors that affect them. This study uses a descriptive qualitative approach with the main informants, namely grade VIII students, subject teachers, and homeroom teachers. Data sources were obtained from direct observations, in-depth interviews, and documentation of learning activities. The data analysis technique uses the Miles and Huberman interactive model, namely data reduction, data presentation, and conclusion drawn. The results showed that students' learning interests were in the medium category, influenced by internal factors such as motivation, perception of the material, and curiosity; as well as external factors such as teachers' teaching methods, the role of parents, and learning environment conditions. Teachers who can create an interactive and fun learning atmosphere are proven to increase students' interest in learning. Family support is also a significant factor in encouraging students' active involvement in the learning process.
Efektivitas Teknik Assertive Training Untuk Mengurangi Bullying Di Pondok Pesantren Modern Al-Istiqamah Ngatabaru Safitri, Devi Ayu; Nurwahyuni, Nurwahyuni; Fitriani, Dian; Puswiartika, Dhevy
Jurnal Ilmiah Dikdaya Vol 15, No 2 (2025): SEPTEMBER
Publisher : Universitas Batanghari Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33087/dikdaya.v15i2.819

Abstract

PenelitianinibertujuanuntukmelihatefektivitaslayanankonselingkelompokdenganTeknikAssertive Training untuk mengurangi bullying di PPM Al-Istiqamah Ngatabaru khususnya kelas IX FB, subjek dalam penelitianiniberjumlah8santri.Teknikpengumpulandatadalampenelitianiniadalahkuesionerkorbanbullying Olweus. Data yang telah diperoleh diolah dan dianalisis menggunakan metode deskriptif dan uji hipotesis menggunakanrumusWilcoxonSignedRankTest.Hasilanalisisdeskriptifmenunjukkanbahwasebelumdiberikan layanankonselingkelompokTeknikAssertiveTrainingterdapat4santrikorbanbullyingdenganklasifikasitinggi dan 4 santri korban bullyingdengan klasifikasi sedang. Setelah diberikan layanan konseling kelompok Teknik AssertiveTraining sebanyak4kalipertemuan, terdapat3santrikorban bullyingdenganklasifikasisedangdan5 santrikorbanbullyingdenganklasifikasirendah.HasilujihipotesismenunjukkanbahwaThitung<Ttabelmaka hipotesisnol(Ho)ditolakyangartinyaTeknikAssertiveTrainingefektivuntukmengurangiperilakubullyingpada santridiPPMAl-IstiqamahNgatabaru.Halinimembuktikanjikakonselingkelompok TeknikAssertiveTraining dapat mengurangi perilaku bullying di PPM Al-Istiqamah Ngatabaru