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All Journal JSFK (Jurnal Sains Farmasi & Klinis) Herbal Medicine Journal
Safyanty, Rahmi
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Implementasi Penyesuaian Obat Diabetes pada Saat Puasa Ramadan dan Pengaruhnya Terhadap Nilai HbA1c Safyanty, Rahmi; Andrajati, Retnosari; Supardi, Sudibyo; Dewi Sartika, Ratu Ayu
JSFK (Jurnal Sains Farmasi & Klinis) Vol 7 No 2 (2020): J Sains Farm Klin 7(2), Agustus 2020
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.7.2.126-134.2020

Abstract

This study aimed to evaluate the effect of diabetes medication adjustment during Ramadan fasting according to the recommendation of International Diabetes Federation-Diabetes and Ramadan International Alliance (IDF-DAR) to HbA1c values in type-2 diabetes mellitus patients. The study was conducted at a hospital in Jakarta, Indonesia with a cross-sectional study design involving 80 ambulatory patients with type-2 DM who fasted during Ramadan in 2016. About 60% of patients used oral antidiabetes drug (OAD), mostly the combination of biguanide + sulfonylurea drugs (27.5%). The adjustments were made in which 56.2% was in accordance with IDF-DAR recommendations. The study showed that the HbA1c values decreased insignificantly (p = 0.082) from 8.75 ± 1.90 to 8.63 ± 1.82 after the adjustment. The appropriate drug adjustment based on IDF-DAR had a significant effect on the HbA1c value of DM patient with p-value 0.030 (p < 0.05).The discrepancy of drug use based on IDF-DAR 3.222 times greater caused uncontrolled HbA1c. The most influential variable to HbA1c value was drug type with p-value 0.006 (p < 0.05). Improper adjustment of Insulin or combination insulin-OAD caused HbA1c value 5 times greater to be uncontrolled than OAD.
Analisis Pola Penggunaan Obat Analgetik Pada Pasien Neurologis di RSUD Padang Panjang Marjoni, Mhd Riza; Safyanty, Rahmi; Sari, Lidya Puspita
Herbal Medicine Journal Vol 8 No 2 (2025): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58996/hmj.v8i2.164

Abstract

Neuropathic pain represents a complex clinical challenge and often requires long-term pharmacological therapy. The prescribing patterns of analgesic medications in managing neuropathic pain serve as important indicators for evaluating therapeutic effectiveness, rationality, and individualization. This study aims to analyze the characteristics of analgesic prescribing patterns among neurological outpatients at the Neurology Outpatient Clinic of RSUD Padang Panjang in 2025. A retrospective observational method was employed, involving 100 neurological patient prescriptions selected through purposive sampling. Data were extracted from prescription sheets and patient eligibility forms, then analyzed descriptively to assess prescription characteristics, combination patterns, and diagnostic distribution. The findings revealed that Eperison was the most frequently prescribed medication (71%), followed by sodium diclofenac (56%) and gabapentin (51%). Triple-drug therapy was the most common combination (35%), with sodium diclofenac–eperison–gabapentin being the predominant regimen (40% of triple combinations). The most common diagnosis was low back pain (31.42%), followed by arthrosis (8.57%). The prescribing pattern reflects a polypharmacy approach that integrates muscle relaxants, NSAIDs, and anticonvulsants. The dominance of combination therapies highlights the complex pathophysiology of neurological pain and underscores the need for evidence-based protocol standardization.
Co-Authors Dewi Sartika, Ratu Ayu Mhd. Riza Marjoni Retnosari Andrajati Sari, Lidya Puspita Sudibyo Supardi