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All Journal Health Information : Jurnal Penelitian Jurnal Abdi Insani Media Kesehatan Politeknik Kesehatan Makassar Jurnal Analis Kesehatan Kendari
Jakaria, Febrianti
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Pola Pertumbuhan Jamur Candida spp. pada urin Penderita Diabetes Melitus dengan Glukosa Terkontrol dan Tidak Terkontrol: Penelitian Laboratorium Anwar, Aan Yulianingsih; Jakaria, Febrianti
Health Information : Jurnal Penelitian Vol 15 No 3 (2023): September-Desember
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/hijp.v15i3.1134

Abstract

Diabetes mellitus is a chronic metabolic disorder caused by the pancreas not producing enough insulin or the body being unable to use the insulin produced effectively. DM sufferers who have uncontrolled glucose suffer from abnormalities in the function of the main defense cells. DM sufferers experience disruption of these main defense cells due to an imbalance in the functions of chemotaxis and phagocytosis which makes diabetes mellitus sufferers more susceptible to infection. High blood sugar levels also damage the system, thereby reducing the sufferer's sensitivity to Candida albicans fungal infections. The genital area in diabetes mellitus patients contains a lot of glucose which is a nutrient for fungal growth. The aim of this research was to examine the growth patterns of Candida spp. In the urine of DM sufferers, glucose is controlled and uncontrolled. The method used is descriptive analysis with a cross sectional design. The results of the study showed that of the 30 respondents with controlled glucose, 1 was found to be positive for Candida spp. Meanwhile, 11 of the 30 respondents with uncontrolled glucose were found to be positive for Candida spp. In his urine. The conclusion of the research is that there is a relationship between the growth of Candida spp. In controlled and uncontrolled glucose with p value (0.001<0.05).
Deteksi Gen Jamur Candida spp. pada Swab Tenggorok Penderita Tuberculosis dengan Metode Polymerase Chain Reaction Yulianingsih, Aan; Basri, Acce; Jakaria, Febrianti
Health Information : Jurnal Penelitian Vol 14 No 1 (2022): Januari-Juni
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/hijp.v14i1.459

Abstract

Pulmonary tuberculosis is the leading cause of death associated with the Mycobacterium tuberculosis complex globally. The incidence of tuberculosis is calculated as dividing the number of new cases of the disease in a year in one hundred thousand population. Many risk factors associated with TB are coinfection with the fungus Candida spp. Coexistence between fungal pathogens and pulmonary TB is a common clinical condition in immunosuppressed patients. Thus, there is a need for screening in patients with tuberculosis co-infected with Candida spp, especially in cases of patients with inadequate response to OAT therapy. The purpose of this study was to determine the candida spp gene in throat swabs of TB patients at the Kalumata Health Center. The method used is descriptive analytic with a cross sectional design. The genes used were C. albicans (665 bp), C. Parasilopsis I (837 bp), C. Parasilopsis II (310 bp), C. guilliermondii (205 bp) and C. lusitaniae (799 bp). The results showed that from 30 samples found 7 sampels (23,3%) Candida albicans species, Candida parasilopsis II as many as 8 samples (26.7%) and 15 samples were negative (50%). The conclusion of this study is that from 30 samples, 15 samples were detected that had the Candida spp gene.
ANALISIS KADAR ALP (ALKALINE PHOSPATASE) PADA IBU HAMIL TRIMESTER III DI WILAYAH KERJA PUSKESMAS GAMBESI KOTA TERNATE SELATAN Jakaria, Febrianti; Nikma; Irma Berliana Hi. Lewa; Samad Hi. Husen
Jurnal Analis Kesehatan Kendari Vol. 7 No. 1 (2024): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 7 (1) Desember 2024)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v7i1.334

Abstract

ALP is present in almost all body tissues, starting from the liver, kidneys, intestines and placenta. The placenta in pregnant women is a food transport medium from mother to fetus with the help of the ALP enzyme, where the ALP enzyme breaks down proteins into amino acids. ALP is an enzyme used to assess hepatocellular and hepatobiliary disorders. This enzyme is found in bones, liver and placenta. ALP in liver cells is found in sinusoids and bile duct membranes, apart from that, ALP is often found in osteoblast activity. Normal values ​​are higher in children, pregnant women and in bone injuries. Objective: Determine ALP levels in third trimester pregnant women in the working area of ​​the Gambesi Community Health Center. Method: The type of research used in this research is descriptive. Descriptive research is carried out on a group of objects which usually aims to describe or provide an overview of the object being studied as it is without carrying out analysis. Results: In this study, the sample used was 23 people obtained from pregnant women in the third trimester in the working area of ​​the Gambesi Health Center, South Ternate City using accidental sampling. Based on the research results, examination of ALP levels obtained high results from 21 respondents and normal results from 2 respondents. Conclusion: Based on the results of research on ALP (Alkaline phosphatase) levels in pregnant women in the third trimester in the working area of ​​the Gambesi Health Center, South Ternate City using the Selectra Pro Xs and Microlab 300 tools. An increase in ALP levels was found in 21 respondents and 2 respondents were normal.
PEMANFAATAN MEDIA ALTERNATIF DALAM ISOLASI BAKTERI PADA URINE PENDERITA INFEKSI SALURAN KEMIH DI WILAYAH DAERAH BINAAN KELURAHAN DUFA-DUFA KOTA TERNATE Erpi Nurdin; Jakaria, Febrianti; Hasanuddin, Riskawati
Jurnal Abdi Insani Vol 11 No 3 (2024): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v11i3.1775

Abstract

Bacteriological examination, especially bacterial culture, is the gold standard for infectious diseases. The very limited availability of culture media encourages the use of alternative media, especially to see the presence of bacteria in the urine of patients with Urinary Tract Infections (UTIs). The price of semi-synthetic culture media is quite expensive and it is difficult for producers to obtain it in the North Maluku region, especially in Ternate City. The use of this alternative media is expected to provide direct benefits to detect the presence of bacteria through the urine of patients with UTIs and improve the knowledge and skills of ATLM cadres regarding the procedure for using alternative media. The use of tuna as one of the alternative media ingredients has not been optimal for the purposes of microbiology laboratory diagnostics. Carried out in the form of socialization which is implemented in the form of lectures, presentations of materials by the community service team with material on the use of alternative media for examining bacteria that cause UTIs. This activity also involves the activeness of participants by working on assessment worksheets and ending with a post-test activity. In the form of knowledge and application of the Use of alternative culture media based on tuna in examining urinary tract infections in the Dufa-Dufa Village community. The test results showed an increase in the percentage of understanding of community service participants, where at the beginning of the activity there were 54% who did not understand UTI and microbiology laboratory examinations, after receiving education there were no more participants who did not understand. In the choice of understanding enough at the beginning of the test 42% and post test 0%. From the criteria understood at the beginning with only 4%, increased to 48%. In the criteria very understood from 0% increased to 52%. The results of the UTI examination through urine culture with alternative media were that there was UTI in 32 people (64%) and the possibility of UTI in 18 people (36%). Increased understanding of the importance of conducting urine culture examinations related to UTI up to 100%, where 48% understood and 52% understood very much. There were 64% of participants with UTI and the possibility of UTI 36%.
The Effect of Sample Volume Variation on Blood Glucose Measurements Using POCT Devices within the Context of Public Health Services Puasa, Rony; Yulianingsih, Aan; Jakaria, Febrianti; Nikma, Nikma
Media Kesehatan Politeknik Kesehatan Makassar Vol 20 No 2 (2025): Media Kesehatan
Publisher : Direktorat Politeknik Kesehatan Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/medkes.v20i2.1798

Abstract

Blood glucose testing is a crucial step in the detection and monitoring of diabetes mellitus, especially within the context of public health services. The use of Point-of-Care Testing (POCT) devices has become a practical choice due to their speed and ease of use. However, the accuracy of the test results can be influenced by various factors, one of which is the volume of the blood sample utilized. This study aims to evaluate blood glucose measurements using variations in sample volume on a POCT device. The research employed a laboratory experimental design with a within-subject approach. A total of 55 respondents participated in the study. The blood sample volume variations tested were 0.3 µl, 0.5 µl, and 0.7 µl. The measurements were carried out using the Easy Touch POCT device, and the results were compared with a standard laboratory control instrument. The study findings indicate that a blood sample volume of 0.7 µl produced glucose values most consistent with the standard laboratory results, where, based on SPSS analysis, the p-value was > 0.05 (0.137 > 0.05), indicating no significant difference between the POCT measurements and the standard laboratory instrument at this volume. In contrast, sample volumes of 0.3 µl and 0.5 µl showed significant differences compared to the reference values (p < 0.05), which could affect the accuracy of the measurements and potentially impact the accuracy of diagnosis and patient monitoring. Based on these results, it can be concluded that the volume that yields the highest accuracy for glucose testing using the Easy Touch POCT device is 0.7 µl. This study highlights the importance of standardizing blood sample volume in the use of POCT to enhance the accuracy of test results, particularly in primary healthcare settings such as community screening programs or public health centers (puskesmas).
Co-Authors Aan Yulianingsih Anwar Basri, Acce Erpi Nurdin Hasanuddin, Riskawati Irma Berliana Hi. Lewa Nikma Nikma, Nikma Puasa, Rony Samad Hi. Husen Yulianingsih, Aan