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All Journal Indonesian Journal of Tropical and Infectious Disease Jurnal Respirologi Indonesia Jurnal Respirasi (JR)
Indriani, Sri Indah
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Earth & Planetary Sciences Health Professions Medicine & Pharmacology Public Health

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C-Reactive Protein and Procalcitonin as Markers for Post-Bronchoscopic Complications: A Literature Review Indriani, Sri Indah; Yovi, Indra; Syaf, Syarlidina; Simatupang, Elvando Tunggul Mauliate
Jurnal Respirologi Indonesia Vol 44, No 2 (2024)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v44i2.638

Abstract

In the respiratory system, bronchoscopy is a basic procedure utilized for both diagnostic and therapeutic purposes. Despite being a generally safe procedure, bronchoscopy can result in complications that range in severity from moderate to severe. Pulmonary infection is among the potential complications that can happen after a bronchoscopy procedure. An incidence of 0.2% to 5.2% has been described typically for complications such as empyema, lung abscess, and pneumonia that may develop after bronchoscopy procedures. Although these complications are uncommon, their prognosis can be quite bad. The risk of pulmonary infection, specifically pneumonia, has been related in several studies to sepsis and mortality in patients enduring bronchoscopy procedures. The initiation of the infection exposure process into the lung can be assisted through a variety of factors, including the underlying diagnosis and the type of intervention performed during the bronchoscopy procedure. A critical complication that needs additional consideration is the potential transmission of infection through bronchoscopy procedures. It is beneficial to consider prophylactic antibiotics before a procedure due to the possibility that infectious agents will be transferred from one patient to another. Antibiotic prophylaxis may involve the utilization of C-reactive protein (CRP) and Procalcitonin (PCT) testing as determining parameters. Serial PCT and CRP 24–96 hours post-bronchoscopy procedure might help to determine one of the post-bronchoscopy complications.
Lung Abscess Located in Lesion of Lung Tumor and Multiple Cavities due to Pulmonary Tuberculosis: A Case Report Indriani, Sri Indah; Simatupang, Elvando Tunggul Mauliate; Wibowo, Adityo; Makmur, Andreas; Fidiawati, Wiwit Ade
Jurnal Respirasi Vol. 10 No. 1 (2024): January 2024
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v10-I.1.2024.55-60

Abstract

Introduction: People with tuberculosis (TB) have an increased risk of pulmonary cancer. They are also disproportionately affected by risk factors like immune suppression, smoking, and alcohol misuse. A lung tumor is reported to have occurred after an episode of TB, but we reported a patient with a lung tumor with co-infection TB and lung abscess at the same time. Case: A 73-year-old man was hospitalized at Arifin Achmad General Hospital, Pekanbaru, with a 3-day history of bloody cough 2-3 times a day, 1-2 tablespoons estimated by the patient for blood from the cough. The patient had a cough with white phlegm in the last 4 months before the bloody cough. The patient also had a fever, night sweats, a limp body, decreased appetite for 6 months, and decreased body weight by 15 kg in the last year. Heterogenic consolidation on the superior lobe of the lung with prominence compression and irregular boundaries in the apex was found. We found an air bronchogram and multiple cavities with air-fluid levels inside the lesion. We also found a satellite nodule in the inferior lung and a mass connected with the chest wall. GeneXpert showed low detection for Mycobacterium tuberculosis. The patient was diagnosed with a left lung abscess, pulmonary TB, left lung tumor T4N2M1a, unspecified type of tumor stage IVA PS2, and osteoporosis. Conclusion: Lung tumors could also be diagnosed with co-infection TB. Proper diagnosis to make sure cancer and TB are co-infected is necessary. Therefore, it will not be just a single disease that is treated.
Diagnosis Approach of Endobronchial Tuberculosis: Literature Review Ginting, Mario Oktafiendi; Indriani, Sri Indah; Simatupang, Elvando Tunggul Mauliate
Indonesian Journal of Tropical and Infectious Disease Vol. 13 No. 1 (2025)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v13i1.60257

Abstract

Pulmonary tuberculosis (PTB) remains a global health problem and the leading cause of death from infectious diseases. Indonesia as an endemic country and the second highest contributor of PTB cases in the world provides support and attention to PTB case finding and treatment success. Endobronchial tuberculosis (EBTB) is problematic PTB because the lesions are often not detected by sputum examination and chest X-ray. Clinically, there is no significant difference in symptoms between TB and EBTB. In general, EBTB gives a more severe clinical appearance due to airway stenosis. Bronchoscopy and thoracic computed tomography scan (CT scan), along with microbiological investigations, are the most useful diagnostic tools for confirming and evaluating tracheobronchial stenosis. In addition, bronchoscopy can also be used as a longterm treatment in cases of EBTB due to airway stenosis. The goals of treatment are the eradication of Mycobacterium tuberculosis (Mtb) bacilli with antituberculosis drugs (ATD) and the prevention of airway stenosis. Intervention of bronchoscopic techniques and surgery are required for those patients who develop severe tracheobronchial stenosis that causes significant symptoms, including dyspnea, repeated post-obstructive pneumonia or bronchiectasis. The most common complications of EBTB are airway stenosis, atelectasis, hemoptysis and shortness of breath accompanied by wheezing despite the administration of ATD. Bronchoscopic intervention can support the acceleration of EBTB treatment, prevent repeated hospitalizations and improve the quality of life of patients. Acceleration of diagnosis and administration of ATDs in a complete and routine way is expected to reduce morbidity and even mortality rates in EBTB cases.
Co-Authors Adityo Wibowo, Adityo Andreas Makmur, Andreas Ginting, Mario Oktafiendi INDRA YOVI Simatupang, Elvando Tunggul Mauliate Syaf, Syarlidina Wiwit Ade Fidiawati