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All Journal Indonesian Journal of Tropical and Infectious Disease The International Journal of Tropical Veterinary and Biomedical Research Journal of International Surgery and Clinical Medicine
Maulina, Novi
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Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

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The Relationship Between Tuberculosis Knowledge and The Attitudes and Behaviors Of Dayah Students Rahman, Muhammad; Kurniawan, Ferry Dwi; Habibie, Yopie Afriandi; Arliny, Yunita; Maulina, Novi
Journal of International Surgery and Clinical Medicine Vol. 4 No. 2 (2024): (Available online: 1 December 2024)
Publisher : Surgical Residency Program Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jiscm.v4i2.60

Abstract

Introduction: Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis and is one of the leading causes of death worldwide. Indonesia ranks second in global TB case counts, with a high transmission rate, particularly in high-risk environments such as Islamic boarding schools. This study aims to evaluate the knowledge, attitudes, and behaviors related to TB among students at Dayah Madrasah Aliyah Swasta Babun Najah in Banda Aceh. Additionally, it will analyze the relationship between their knowledge, attitudes, and behaviors in the context of TB prevention. Methods: This study employed an observational analytic method with a cross-sectional design and utilized cluster sampling. Primary data were gathered through questionnaires. The research was conducted at Dayah Madrasah Aliyah Swasta Babun Najah, located in the Ulee Kareng District of Banda Aceh, on August 29, 2024. Bivariate analysis was performed using the non-parametric Spearman's rank correlation coefficient test. Results: A total of 90 students participated in the study. The findings revealed that 67.8% of respondents had good knowledge, 78.9% demonstrated positive attitudes, and 47.8% exhibited good behaviors regarding tuberculosis (TB) prevention. Spearman Rank analysis indicated a moderately strong positive correlation between knowledge and attitudes (r = 0.527) and between knowledge and behaviors (r = 0.535), with a p-value of less than 0.025. Conclusion: Enhancing knowledge among students is crucial for fostering better attitudes and behaviors related to TB prevention, particularly in high-risk environments.
Description of Mothers' Knowledge, Attitudes, and Behavior Regarding Deworming The Children Against Soil-Transmitted Helminthiasis at The Lampaseh Health Center in Banda Aceh City Suryawati; Putra, Teuku Romi Imansyah; Liansyah, Tita Menawati; Maulina, Novi; Maulidina, Rizka Yuliani; Al-Muchtari, Teuku Az Zikri
Indonesian Journal of Tropical and Infectious Disease Vol. 12 No. 3 (2024)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v12i3.54434

Abstract

Helminth infections are a significant public health problem in developing countries, including Indonesia, where the prevalence ranges from 60% to 90%. One common helminth infection is Soil-Transmitted Helminthiasis (STH), which particularly affects children. One of risk factors is children who lack personal hygiene, especially when they are playing with soil. The increased incidence of STH can be prevented by deworming programs, and the role of parents, especially maternal parenting. This study aims to determine the description of the level of knowledge, attitudes and behavior of mothers on deworming the children against STH at the Lampaseh Health Center, Banda Aceh City, Indonesia. This research is descriptive with a cross-sectional design. The sample consists of mothers with children aged 2-12 years, selected using accidental sampling techniques. Data were collected through interviews using structured questionnaires. The results showed that the level of maternal knowledge of deworming the children against STH categorized as good (95.1%), quite good (3.9%), and less good (1.0%) as well as the attitude of mothers was categorized into good (51.5%), quite good (46.6%), and less good (1.9%). However, the mother’s behavior was good (69.9%) and less good (30.1%). The conclusion was that the knowledge, attitudes, and behavior of mothers on deworming the children against STH need to be maintained and improved.
The Role of Gut Microbiota-derived Tryptophan Metabolites in Mycobacterium tuberculosis Infection: A Mini-Review Maulina, Novi; Hayati, Zinatul; Hasballah, Kartini; Zulkarnain, Zulkarnain; Zulkifli, Baidillah
The International Journal of Tropical Veterinary and Biomedical Research Vol 7, No 2 (2022): Vol. 7 (2) November 2022
Publisher : The Faculty of Veterinary Medicine of Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/ijtvbr.v7i2.30165

Abstract

The gut microbiota has a major contribution in human physiology and influences disease pathogenesis, including in tuberculosis (TB) lung infection. Gut-lung axis has demonstrated the interplay of these two organs, mediated by metabolites produced by the gut microbes or derived from host molecules transformation. Tryptophan (Trp) is one of the essential aromatic amino acids catabolized as kynurenine, serotonin (5-hydroxytryptamine), and indole derivatives, including indole propionic acid (IPA), via 3 pathways. The latter was microbiota-derived Trp catabolism, which has known to have an immunomodulatory role, as ligands for Aryl hydrocarbon Receptor (AhR). Intriguingly,Mycobacterium tuberculosisrequired Trp as a nitrogen source, especially in CD4+ T cells-generated stress, to survive in the phagosome of macrophage and to cause disease. Recently, IPA is identified as a new anti-mycobacterial compound, which is specific and has broad spectrum of anti-mycobacterial activity. The structural similarity of this gut microbiota-derived metabolite and Trp allows IPA to inhibit the TrpE anthranilate synthase in Trp biosynthesis pathway in Mtb. In this review, wesummarize findings from recent work by focusing on the role of Trp metabolites in host cells in TB infection.A better understanding of this chemical signal could potentially serve as a novel strategy for managing this chronic inflammatory disease.
Histopathological profile and radiological features of lung cancer with and without a history of pulmonary tuberculosis at dr. Zainoel Abidin Hospital, Banda Aceh Mardhatillah; Kurniawan, Ferry Dwi; Maulina, Novi; Arliny, Yunita; Sakdiah; Andayani, Novita
Journal of International Surgery and Clinical Medicine Vol. 4 No. 2 (2024): (Available online: 1 December 2024)
Publisher : Surgical Residency Program Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jiscm.v4i2.64

Abstract

Introduction: Lung cancer is one of the types of malignancies that is the leading cause of cancer deaths worldwide. In Indonesia, the incidence of lung cancer is quite high, with pulmonary TB as a risk factor that can increase the risk of lung cancer in the future. This study aims to describe the histopathological profile and radiological picture of lung cancer patients in patients with and without a history of pulmonary TB at dr. Zainoel Abidin Hospital Banda Aceh. Methods: This study uses retrospective methods and univariate analysis. The subjects of this study are lung cancer patients at dr. Zainoel Abidin Hospital from January 2022 to December 2023. Result: The results of this study showed that of the 184 patients, 6.5% of them had lung cancer with a history of pulmonary TB, while the other 93.5% had lung cancer without a history of pulmonary TB. Of the two groups of lung cancer, the majority of patients were aged 51-60 years (32.6%), male (83.7%), still working (81%), from Aceh (99.5%), and Muslim (99.5%). Most lung cancer patients were diagnosed at stage IV (86.4%), with Squamous Cell Carcinoma being the most common type of histopathology (57.1%). In lung cancer patients with a history of pulmonary TB, post-TB lesions are often found, such as fibrosis (83.3%), calcification (50%), cavitation (33.3%), pleural thickening (16.7%), and atelectasis (8.3%). Conclusion: Efforts to prevent lung cancer, especially in patients with a history of pulmonary TB, need to be continued so that the risk of developing lung cancer can be reduced.
Co-Authors Al-Muchtari, Teuku Az Zikri Habibie, Yopie Afriandi Kartini Hasballah Kurniawan, Ferry Dwi Mardhatillah Maulidina, Rizka Yuliani Novita Andayani, Novita Rahman, Muhammad Sakdiah Suryawati Teuku Romi Imansyah Putra Tita Menawati Liansyah Yunita Arliny Zinatul Hayati Zulkarnain Zulkarnain Zulkifli, Baidillah