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Roosevelt, Alfreds
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Journal : Jurnal Farmasi Sandi Karsa

 1 
Uji Toksisitas Ekstrak Rimpang Temu Hitam (Curcuma aeruginosa Roxb.) Terhadap Larva Udang (Artemia salina Leach) dengan Metode Brine Shrimp Lethality Test (BSLT) Zulfiah, Zulfiah; Megawati, Megawati; Herman, Herman; H. Ambo Lau, Sulfiyana; Hasyim, Muh. Farid; Murniati, Murniati; Roosevelt, Alfreds; Kadang, Yuniharce Kadang; AR, Nurul Izza; Patandung, Gerfan
Jurnal Farmasi Sandi Karsa Vol 6 No 1 (2020): Jurnas Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v6i1.67

Abstract

Penelitian ini bertujuan mengetahui adanya potensi toksisitas dari ekstrak rimpang temu hitam terhadap larva udang Artemia salina Leach dengan metode BSLT. Desain penelitian yang digunakan adalah eksperimental laboratorium yang dilaksanakan di Laboratorium Biologi Sekolah Tinggi Ilmu Farmasi Makassar. Tumbuhan rimpang temu hitam (Curcuma aeruginosa Roxb.) merupakan salah satu tumbuhan yang berada di Indonesia dan memiliki banyak khasiat. Tanaman ini mengandung senyawa alkaloid, saponin, flavonoid dan kurkuminoid. Penelitian ini mengunakan sampel ekstrak etanol, hewan uji yang digunakan berupa Artemia salina Leach yang dibagi dalam 5 kelompok tiap kelompok terdiri dari 10 ekor larva yang dimasukkan kedalam vial. Konsentrasi yang digunakan adalah 20 ppm, 40 ppm, 60 ppm, 80 ppm dan 100 ppm dan terdapat juga kontrol negatif. Pengamatan terhadap larva yang mati dilakukan 24 jam setelah pemberian sampel uji. Data persen kematian larva Artemia salina Leach dibuat persamaan regresi linier dengan membuat persamaan garis lurus yang menghubungkan antara nilai log konsentrasi dan nilai probit. Hasil penelitian bahwa ekstrak etanol rimpang temu hitam memiliki nilai LC50 37,73115 ppm. Pemberian kelima konsentrasi yang berbeda pada penelitian ini menunjukkan potensi toksisitas terhadap larva Artemia salina Leach.
Uji Efek Antimikroba Infusa Daun Pare (Momordica charantia L.) Terhadap Pertumbuhan Staphylococcus aureus Edi Kamal, Sainal; Megawati, Megawati; H. Ambo Lau, Sulfiyana; Hasyim, Muhammad Farid; Murniati, Murniati; Roosevelt, Alfreds; Kadang, Yuniharce; AR., Nurul Izza; Patandung, Gerfan
Jurnal Farmasi Sandi Karsa Vol 5 No 2 (2019): Jurnal Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v5i2.58

Abstract

Penelitian ini merupakan penelitian eksperimen untuk mengetahui efek antimikroba infus Daun Pare (Momordica charantia L.) terhadap pertumbuhan Staphylococcus aureus. Tujuan dari penelitin ini adalah untuk mengetahui efek antimikroba infus Daun Pare (Momordica charantia L.) terhadap pertumbuhan Staphylococcus aureus. penelitian ini dilakukan di Laboratorium Mikrobiologi Politeknik Kesehatan Makassar. Hasil penelitian menunjukkan bahwa Daun Pare mempunyai efek antimikroba terhadap Staphylococcus aureus yaitu konsentrasi 5% sebesar 10 mm, 10% sebesar 14,66, dan konsentrasi 20% sebesar 19 mm, sedangkan kontrol negatif tidak menimbulkan efek.
Uji Identifikasi Senyawa Alkaloid Ekstrak Metanol Daun Kelor (Moringa oleifera Lamk) Menggunakan Metode Metode Kromatografi Lapis Tipis Zulfiah, Zulfiah; Herman, Herman; AR., Nurul Izza; Kadang, Yuniharce; Roosevelt, Alfreds; H. Ambo Lau, Sulfiyana; Murniati, Murniati; Hasyim, Muhammad Farid; Megawati, Megawati; Patandung, Gerfan
Jurnal Farmasi Sandi Karsa Vol 6 No 2 (2020): Jurnas Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v6i2.75

Abstract

Penelitian ini adalah hasil observasi laboratorium. Tujuan penelitian ini adalah untuk mengidentifikasi senyawa alkaloid yang terdapat pada daun kelor (Moringa oleifera L.). Identifikasi alkaloid dilakukan dengan metode maserasi dan dilanjutkan dengan metode Kromatografi Lapis Tipis (KLT). Hasil penelitian menunjukan daun kelor positif mengandung senyawa alkaloid. Harga Rf yang didapat 0,8.
Factors Causing Expired Medicine in Puskesmas Cendrawasih Makassar City Hasyim, Muhammad Farid; Roosevelt, Alfreds; Enriana, Irma
Jurnal Farmasi Sandi Karsa Vol 8 No 1 (2022): Jurnal Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v8i1.105

Abstract

Pharmaceutical services carried out at the (community health centers are one of the efforts to improve the quality of health services for the community. This pharmaceutical service can be supported by good drug management, which is expected to prevent and overcome drug problems, such as problems with expired drug stocks. This problem can cause losses for the Community health centers and the government. This study aims to identify drug management, and determine the factors that cause expired drugs at Cendrawasih Health Center Makassar City. This type of research is a qualitative research. Data were obtained by conducting interviews with an informant and observing and reviewing expired drug stock documents. The results of the study obtained that there were 20 types of drugs that expired from January to June 2021. The causes of expired drugs were the time the drug was brought to the health center close to the drug expiration time, errors in the planning process to distribution of drugs outside the health center for unknown causes so the number of drugs that arrived at the Cendrawasih Health Center did not match the needs, the Covid-19 pandemic caused the community health centers to not be able to carry out counseling and distribution of drugs optimally. The conclusion of this study is that the implementation of drug management at the Cendrawasih Health Center has gone well but has not been maximized, besides that factors from outside the community health centers and the Covid-19 pandemic are also factors that cause expired drug stocks.
Overview of the Level of Knowledge of Narisa Pharmacy Consumers Against Cough Self-Medication Herman, Herman; Roosevelt, Alfreds; Kasman, Umrah
Jurnal Farmasi Sandi Karsa Vol 8 No 2 (2022): Jurnal Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v8i2.114

Abstract

Self-medication is an effort that most people make to deal with complaints or symptoms of disease before they decide to seek help at a health service center/health worker. Coughing is a reflection that is aroused by irritation of the lungs or respiratory tract. This study aims to describe the level of knowledge of Narisa pharmacy consumers on cough self-medication. This research was conducted from September to November 2022 at the Narisa Pharmacy. This type of research uses a descriptive method using a questionnaire. With a total sample of 88 respondents, the sample was taken using a non-probability sampling technique, namely accidental sampling. The results of this study indicate that the percentage results are 93.58%. Based on the results of the percentage of respondents' answers, it can be concluded that the level of knowledge of Narisa pharmacy consumers is categorized as high level of knowledge.
The Place to Purchase Drugs for Community Self-Medication at Green Hills Moncongloe Housing, Maros Regency Asrina, Rina; Roosevelt, Alfreds; Julyiansyah, Arqian
Jurnal Farmasi Sandi Karsa Vol 9 No 1 (2023): Jurnal Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v9i1.116

Abstract

Self-medication or self-medication is part of the community's efforts to treat minor ailments by using over-the-counter drugs, limited over-the-counter drugs and mandatory pharmacy drugs without consulting a doctor first. Most people self-medicate because they don't have time to go to the doctor, the distance to the puskesmas, hospital or doctor's office is far from home. So that people choose where to buy drugs at pharmacies, grocery stalls, minimarkets and drugstores. The purpose of this study was to find out where to buy drugs for self-medication in the Green Hills Moncongloe Housing Complex, Maros Regency. The method used in this research is descriptive method, namely research that includes surveys with data collection techniques in the form of questionnaires. This research was conducted at the Green Hills Moncongloe Housing Complex, Maros Regency which was carried out in February - March 2023 by distributing questionnaires to 50 respondents. From the results of the study it can be seen that of the 50 respondents, 29 people (58%) bought drugs at pharmacies, 16 people (32%) at grocery stalls, 3 people (6%) minimarkets, and finally 2 people (4%) drugstores. So it can be concluded that more people choose places to buy medicines at pharmacies because people believe that medicines sold at pharmacies can be trusted for their quality and authenticity and the public can obtain information about the drugs they buy.
Potensi Hiperglikemia Kombinasi Ekstrak Kulit Buah Semangka (Citrullus lanatus) Dan Ekstrak Kulit Buah Naga Merah (Hylocereus polyrhizus) Edi Kamal, Sainal; Roosevelt, Alfreds; Patandung, Gerfan; Amiruddin, Achmad
Jurnal Farmasi Sandi Karsa Vol 9 No 2 (2023): Jurnal Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v9i2.129

Abstract

This study aims to determine the potential hyperglycemia of the combination of Watermelon Skin Extract (Citrullus lanatus) and Red Dragon Fruit Skin Extract (Hylocereus polyrhizus). The research method used is the alloxane induction method. Rats were divided into 5 groups, namely positive control given metformin 45 mg / Kg BB, negative control given Na. CMC 1% w/v, and variations of test groups given combination extracts with concentration variations of 6% and 13.4%; 9% and 16.4%; and 12% and 19.4% then each group was induced alloxane at a dose of 24 mg / 200g BB. The results of the study on the negative control given NaCMC 1% did not show a decrease in blood sugar levels, in the positive control given metformin 45 mg / KgBB showed an average percent decrease of 94.12%, in the combination extract test group with a dose of 6% and 13.4% showed an average percent decrease of 25.04%; 9% and 16.4% % showed an average percent decrease of 24.69%; and 12% and 19.4% % showed an average percent decrease of 55.61%. Based on the results of this study, a combination extract of 12% and 19.4% can reduce blood sugar levels of white rats. This study proved that red watermelon peel extract and red dragon fruit peel extract have antihyperglycemia effects.
Co-Authors Ali Djamhuri Amiruddin, Achmad AR, Nurul Izza AR., Nurul Izza AR., Nurul Izza Asrina, Rina Edi Kamal, Sainal Edi Kamal, Sainal Enriana, Irma Hasyim, Muh. Farid Hasyim, Muhammad Farid Hasyim, Muhammad Farid Herman Herman Julyiansyah, Arqian Kadang, Yuniharce Kadang, Yuniharce Kadang, Yuniharce Kadang Kasman, Umrah Masri, Anshari Megawati - Patandung, Gerfan Patandung, Gerfan Sulfiyana H. Ambo Lau Veithzal Rivai Zainal Zulfiah, Zulfiah