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Pengaruh Lamanya Pengobatan Terhadap Profil Darah pada Penderita Tuberkulosis Paru di Puskesmas Oesapa Ni Made Susilawati; Novian Agni Yudhaswara; Karol Octrisdey
Jurnal Ventilator Vol. 1 No. 4 (2023): Desember : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v1i4.706

Abstract

Control efforts with the DOTS (Directly Observed Treatment Short-course) strategy have been implemented. The side effects of this drug will continue as long as the sufferer takes it, furthermore anti-TB drugs (OAT) will change the metabolism in the sufferer's body. Chronic effects that arise from OAT treatment include increased levels of uric acid, glucose and hemoglobin in the blood. From the results of a preliminary study, data collection was carried out on the number of pulmonary TB sufferers in Kupang City in 2021, amounting to 385. Of this number, 72 cases were found at the Oesapa Community Health Center who were smear positive for pulmonary TB and had recovered and were still undergoing treatment. For this reason, it is necessary to carry out research to determine blood glucose, uric acid and hemoglobin levels in pulmonary tuberculosis (TB) patients who take OAT (anti-TB drugs) before taking, after taking 2 months and 6 months of treatment. This research method is descriptive and statistical. Statistical analysis using One Way Anova and Linear Regression tests was used to determine the effect of length of treatment on blood profiles in pulmonary tuberculosis sufferers. TB sufferers with anti-tuberculosis drug therapy at the Oesapa Community Health Center based on the age of the patient, there were 11 sufferers aged <30 years (55%), 9 sufferers aged >30 years (45%). Based on gender, 13 sufferers were female (65%), 7 sufferers were male (35%). Hemoglobin levels checked before treatment showed a mean of 13.015 g/dL, during 2 months of treatment 13.185 g/dL, and after 6 months of treatment the mean was 11.94 g/dL. The current blood sugar levels from table 1.3 above which were checked before treatment showed an average of 137.7 g/dL, during 2 months of treatment 145.15 g/dL, and after 6 months of treatment the average was 144.15 g/dL. Uric acid levels were based on the respondent's length of treatment with an average uric acid level before treatment of 6.16 mg/dL, 2 months of treatment 5.92 mg/dL and 6 months of treatment 6.43 mg/dL. Hemoglobin levels, instant blood sugar and uric acid before, 2 months and 6 months of treatment showed a p value <0.05, meaning the data was not normally distributed. The results of the analysis using the Friedman anova test showed a p value (0.137) > 0.05. This means there is no difference in uric acid measurement values ??before, 2 months and 6 months of treatment. The results of the analysis using the Friedman anova test showed a p value (0.142) > 0.05. This means that there is no difference in blood sugar measurement values ??before, 2 months and 6 months of treatment. The results of the analysis using the Friedman anova test showed a p value (0.378) > 0.05. This means there is no difference in Hb measurement values ??before, 2 months and 6 months of treatment
Infeksi Ascariasis Dan Anemia Pada Anak Stunting di Desa Bone, Kabupaten Kupang, Nusa Tenggara Timur Meliance Bria; Ni Made Susilawati
Jurnal Ventilator Vol. 1 No. 4 (2023): Desember : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v1i4.711

Abstract

. Helminth infection is one of the health problems in all tropical countries in the world including Indonesia. Ascaris lumbricoides is one of the Soil Transmitted Helminths (STH). Stunting are the age group that is vulnerable to helminth infection including ascariasis. A. lumbricoides infection can cause serious effects if not treated and without a clean and healthy lifestyle. Therefore, it is necessary to conduct research on the prevalence of A. lumbricoides infection and hemoglobin (Hb) level in its infected hosts. The design of this study was observational analytic with cross sectional study. The subjects of the stunting in Bone Village. The sample technique used in this method is the total population. Diagnosis was performed microscopically by Kato-Katz method and Hb levels were measured using a hematology analyzer. Microscopy examination found 6.4% eggs of A. lumbricoides and a low hemoglobin level of 22,5%, students infected with A. lumbricoides in Bone Village with very low hygiene and sanitation.
Review of Impact and Handling of Potential Antihypertensive Drug Interactions in Chronic Kidney Disease Patients: Review Dampak dan Penanganan Potensi Interaksi Obat Golongan Antihipertensi pada Pasien Penyakit Ginjal Kronis Ni Made Susilawati; Eli Halimah; Siti Saidah
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 1 (2021): (March 2021)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i1.15332

Abstract

Drug interaction is a type of Drug-Related Problems (DRPs) that caneventually increase morbidity and mortality rates. CKD patients have asignificant risk of developing polypharmacy due to comorbid diseases andpharmacokinetics' alteration. The literature review was conducted byexploring all of the articles related to the drug interaction using druginteraction analysis program in CKD patients, which obtained from threedatabases, namely Google Scholar, PubMed, and Science Direct, usingseveral keywords combination. Based on the comprehensive reviewsconducted, it is known that the most common effects of antihypertensivedrug interactions in CKD patients are decreasing effects of antihypertensivedrugs, hypotension, and hyperkalemia. Handling management used for theemergence of potential drug interactions is based on the severity of the druginteractions and complete knowledge of the patients' clinical condition. Themanagement of drug interaction by monitoring blood pressure, diuresis, andpotassium levels; Monitor the related effect symptoms; Monitor the fluidand body weight; Monitor the kidney and heart function. On the conditionwhere the handling management of potential drug interactions is not carriedout, elevated morbidity and mortality rates are the risks of complicationsarising from the drug interactions.
Hubungan Pekerjaan dan Pendidikan dengan Kejadian TB Paru di Kota Kupang Ni Putu Ayu Natalia Dewi; Ni Made Susilawati
Inovasi Kesehatan Global Vol. 1 No. 4 (2024): November: Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v1i4.1231

Abstract

Tuberculosis is an infection disease caused by Mycobacterium tuberculosis and most often infects the lungs. Pulmonary TB cases in Indonesia are the third largest in the world. NTT province occupies the 15th position out of 34th in Indonesia. Kupang city ranks first with the highest incidence of pulmonary TB in NTT. One of the factors that influence pulmonary TB is occupation and education level. This study aims to determine the differences in pulmonary TB incidence based on occupation and education level in Kupang City in 2021. This research was conducted at a health center in Kupang City, experimentally with a cross-sectional design, from March until May 2022. The research sample is secondary data of pulmonary TB patients with a total sample of 395 cases with a sampling technique that is total sampling. The result showed that there was no difference in the incidence of pulmonary TB based on occupation where p = 0,958 (p > 0,05) and there was a difference based on education level where p = 0,048 (p< 0,05). Further research is conducted to strengthen the effect of work and education level on the incidence of pulmonary TB. Keywords: ,
Pemberdayaan Kader Sebaya dalam Pencegahan Tuberkulosis pada Masyarakat di Kelurahan Oesapa Kecamatan Kelapa Lima Kota Kupang Tahun 2024 Ni Made Susilawati; Meliance Bria; Melania Fernanda Bessie
ARDHI : Jurnal Pengabdian Dalam Negri Vol. 3 No. 1 (2025): ARDHI : Jurnal Pengabdian Dalam Negri
Publisher : Asosiasi Riset Pendidikan Agama dan Filsafat Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/ardhi.v3i1.1059

Abstract

Tuberculosis (TB) is one of the ten diseases that most frequently causes death worldwide. This disease is caused by Mycobacterium tuberculosis and lasts a long time. Indonesia ranks third in the world in terms of the number of people suffering from tuberculosis, behind India, China and India. In East Nusa Tenggara, the most cases of tuberculosis are found in Kupang City, and Oesapa Village is one of the places where cases are still quite high. With so many TB cases still occurring, public knowledge about the symptoms, transmission and treatment of the disease is still lacking. It is hoped that empowering teenagers as health drivers will increase public awareness, especially teenagers, about prevention, symptom monitoring, and discovery and treatment of tuberculosis. Tuberculosis education can help teenagers understand the importance of maintaining a clean and healthy lifestyle to reduce TB transmission (1). This community service activity aims to increase youth knowledge and attitudes about pulmonary TB through comprehensive counseling, structured information, and youth empowerment. They also monitor communities for TB symptoms, especially children(2) The results of the activity show that the level of understanding among teenagers about TB disease has increased from 35 percent to 85 percent. There were no TB symptoms at the monitoring stage in the community, especially teenagers, and everyone was in good health. It is hoped that peer cadres (adolescents) can adopt a clean and healthy lifestyle and become pioneers in monitoring the symptoms of tuberculosis in the community to make it easier to find, handle and treat. Peer cadres can transfer information about pulmonary TB to the community, especially teenagers, by implementing Clean and Healthy Living Behavior