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All Journal MKGK (Majalah Kedokteran Gigi Klinik) (Clinical Dental Journal) UGM Majalah Kedokteran Gigi Indonesia ODONTO Dental Journal Dental Journal (Majalah Kedokteran Gigi) B-Dent, Jurnal Kedokteran Gigi Universitas Baiturrahmah Odonto dental journal
Vincensia Maria Karina
Department Of Periodontics, Faculty Of Dentistry, Universitas Gadjah Mada, Yogyakarta
Dentistry Health Professions Medicine & Pharmacology

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Journal : Majalah Kedokteran Gigi Indonesia

 1 
Effect of the application of curcumin (Curcuma Longa) oral gel on periodontal inflammation in patients with type 2 diabetes melitus Nur Rahman Ahmad Seno Aji; Vincensia Maria Karina; Osa Amila Hafiyyah; Kwartarini Murdiastuti; Ahmad Syaify
Majalah Kedokteran Gigi Indonesia Vol 7, No 3 (2021): December
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.69036

Abstract

Patients with Type 2 Diabetes mellitus (T2DM) were more prone to suffer from periodontitis due to unique alteration in host immune response. Application of curcumin oral gel as adjunctive therapy was expected to improve periodontal condition due to its anti-inflammatory properties. The objective of this study was to evaluate the effect of curcumin oral gel on periodontal inflammation in patients with T2DM. Sixteen periodontal pockets (n=16) from patients with T2DM were administered with curcumin oral gel using blunt cannula after periodontal curettage. Gingival Index (GI) and Periodontal Pocket Probing Depth (PPD) were evaluated a month after application. GI was assessed using visible sign of inflammation parameters including swelling, redness and bleeding upon probing. PPD was assessed using UNC-15 periodontal probe. The results were analyzed by Wilcoxon test (two related samples). The results showed that GI before treatment decreased by 51.61% a month post application. There was statistically significant difference (Sig 0.003) between GI mean before and after curcumin application. PPD decreased by 42.81% and showed statistically significant difference (Sig 0.000) by Wilcoxon Test. It is concluded that application of curcumin oral gel post curettage could decrease periodontal inflammation in patients with T2DM.
Chicken bone hydroxyapatite enhances collagen density and osteoblast cell number during bone formation of post-extraction socket wound healing process (an in vivo study) Humani, Maria Bonita Cerebrina; Kintani, Dayinta Sekar; Arindra, Pingky Krisna; Karina, Vincensia Maria; Haniastuti, Tetiana
Majalah Kedokteran Gigi Indonesia Vol 11, No 1 (2025): April
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.103626

Abstract

Tooth extraction is a common dental procedure. Osteoblasts (bone-forming cells) and collagen are key indicators of wound healing following tooth extraction. Hydroxyapatite is a calcium-rich material that promotes the secretion of Fibroblast Growth Factor (FGF), Platelet-Derived Growth Factor (PDGF), and Transforming Growth Factor Beta (TGF-β)—all of which play critical roles in the wound healing process. Chicken bones, a natural source of hydroxyapatite, contain approximately 85% calcium phosphate minerals. This study aimed to determine the effect of chicken bone-derived hydroxyapatite on osteoblast cell count and collagen density in post-tooth extraction wounds in Wistar rats. Thirty male Wistar rats were randomly divided into treatment and control groups. Tooth extraction was performed on the lower left incisor of each rat. Hydroxyapatite was prepared by calcining chicken bones at 700 °C to remove organic material. The resulting hydroxyapatite powder was implanted into the tooth sockets of rats in the treatment group, while the control group received no implantation. Both groups were sutured and treated with povidone-iodine. Three rats from each group were sacrificed on days 3, 5, 7, 10, 14, and 21. Histological samples were prepared using hematoxylin-eosin and Mallory’s Trichrome staining. Osteoblast cells (100× magnification) and collagen density (400× magnification) were examined using a light microscope and Optilab Viewer, across five fields of view per sample. Two-way ANOVA showed significant differences in both osteoblast cell counts and collagen density between groups and across observation days (p < 0.05). Least Significant Difference (LSD) post hoc analysis also revealed significant differences between groups on all observation days (p < 0.05). In conclusion, chicken bone-derived hydroxyapatite significantly increases osteoblast numbers and collagen density during the post-extraction wound healing process in Wistar rats.
Comprehensive gummy smile correction: a case report on combined lip repositioning and crown lengthening Nurbaiti, Mentari Salma; Murdiastuti, Kwartarini; Karina, Vincensia Maria
Majalah Kedokteran Gigi Indonesia Vol 11, No 2 (2025): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.104349

Abstract

A gummy smile, or excessive gingival display (EGD), is a clinical condition in which more than 3–4 mm of gingiva is visible during smiling. This condition often raises aesthetic concerns and may negatively affect self-esteem. This report presents the clinical management of a 26-year-old male patient whose gummy smile was attributed to altered passive eruption, compounded by hyperactivity of the upper lip elevator muscles. To address these issues, a combined surgical approach was employed: crown lengthening and lip repositioning. Crown lengthening was performed on teeth 12, 11, and 22 to establish an appropriate tooth–gingiva ratio, while lip repositioning was carried out to limit excessive elevation of the upper lip. Postoperative evaluations revealed a significant correction of the gingival display and improved tooth dimensions. These results highlight the effectiveness of a combined periodontal and soft tissue surgical approach in achieving harmonious and predictable smile aesthetics.
Co-Authors Ahmad Syaify, Ahmad Handoko, Evan Kurniawan Humani, Maria Bonita Cerebrina Kintani, Dayinta Sekar Kwartarini Murdiastuti Muhammad Yusuf Nur Rahman Ahmad Seno Aji Nurbaiti, Mentari Salma Osa Amila Hafiyyah Padang, Lastry Ruth Pingky Krisna Arindra Pritia, Mardha Ade Rina Meiliyanawaty Sri Pramestri Lastianny, Sri Pramestri Supriatno Suryahapsari, Nastiti Mayangjati Yosaphat Bayu Rosanto