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All Journal Majalah Kedokteran Bandung JOURNAL LA MEDIHEALTICO Ahmad Dahlan Medical Journal
Ihsana, Nuni
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Level of physical fitness of member of Indonesian Medical Association in Bantul, Yogyakarta Ihsana, Nuni; Yuniasih, Dewi; Putri, Rachma Greta Perdana; Annisa, Annisa; Tejosukmono, Ario; Heriyanto, Mochammad Junaidy; Pamungkasih, Wahyu; Rokhmah, Budi Nur; Murdiyanto, Joko
Ahmad Dahlan Medical Journal Vol. 5 No. 1 (2024): May 2024
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Physical inactivity contributed to 7.2% of all-cause mortality. Many research demonstrates that the integration of physical activity and exercise into daily routine prevents chronic disease and lowers mortality. This study aims to assess the physical fitness of members of the Indonesian Medical Association in the Bantul region using a descriptive from secondary data. The subjects were 38 members of the Indonesian Medical Association. Physical fitness data was obtained using the Rockport One Mile Walking Test. Body Mass Index (BMI) is also calculated to describe excessive body fat. The majority of participants are female (52.63%) and participants dominant age ranged between 19 and 44 years old (50%). The participants aged 18 years old showed good physical fitness. The results in participants aged 19 to 44 years were more varied, there were 8 participants, 7 participants, 3 participants 1 participant had fair, good, poor, and very poor physical fitness, respectively. Physical fitness in participants aged 45 to 59 years were 9 and 5 participants showed good and fair physical fitness, respectively. The subjects aged >59 years old have 2 people with good physical fitness and 1 person with fair physical fitness. None of the participants with BMI status underweight, normal weight, or overweight showed poor physical fitness, while participants with obesity had poor and very poor physical fitness. Physical fitness is a multidimensional concept and is related to regular activity.
The Relationship between the Classic Triad of Meningitis and Types of Meningitis Budi Iftiyastuti, Selma Nissa; Rizkita, Leonny Dwi; Ihsana, Nuni; Selohandono, Andrianto
Journal La Medihealtico Vol. 5 No. 4 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i4.1542

Abstract

Meningitis is an inflammatory disease of the meninges caused by infection and non-infection. Based on WHO data for 2023, the CFR (Case Fatality Rate) for meningitis is 5.88%. In 2016 at the Southeast Asian level, Indonesia became the country with the highest mortality rate caused by meningitis. The classic triad of meningitis can assist in the early diagnosis of meningitis so that early management can be carried out to reduce mortality and morbidity if a cerebrospinal fluid examination is not possible immediately. Therefore, a study was conducted to determine the characteristics of meningitis patients, prevalence, and the relationship between the classic triad of meningitis and the incidence of infectious and non-infectious meningitis at Dr. Sardjito General Hospital Yogyakarta in 2017-2021. This study uses a cross-sectional method. The data taken is secondary data from 118 medical records of patients who have been treated. From the results, it was obtained that the highest characteristics and distribution were the age category 0-5 years (27.1%), male sex (51.7%), the most domicile outside DIY (54.2%), no/not yet school (36.4%) not/not yet working (38.1%), bacterial meningitis (39.0%), fever (89.8%), neck stiffness (78.8%). There is a significant relationship between the classic triad of meningitis and the type of meningitis (p-value 0.000). Among the three triads, it turned out that there was a solid relationship between the classic triad of meningitis and the type of infectious meningitis as indicated p-value by neck stiffness 0.000, fever 0.000, and headache 0.000.
Analysis of Functional Disaster Preparedness at Community Health Centers in Mount Merapi Disaster Prone Areas, Sleman Yogyakarta Fadly M. Bima P; Arliono, Tri Yunanto; Wijaya, Oktomi; Ihsana, Nuni; Indarto, Bayu Praditya; Hutomo, Muhammad Agita; Putri, Rachma Greta Perdana; Heriyanto, Mochammad Junaidy; Alim, Ahmad Muttaqin
Ahmad Dahlan Medical Journal Vol. 5 No. 2 (2024): November 2024
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/admj.v5i2.10946

Abstract

Mount Merapi is one of the most active volcanoes in the world, as evidenced by several major eruptions in 1768, 1822, 1849, 1872, and the most recent one in 2010. These events have significantly impacted structures and infrastructure, including health centers. Health centers serve as primary healthcare facilities and are located in areas adjacent to Mount Merapi. Based on their location, there are three health centers situated at the foot of Mount Merapi in the Sleman region of Yogyakarta. These health centers, namely Pakem, Turi, and Cangkringan, are at high risk of potential disasters, ranging from eruptions, cold lava flows, to landslides. In light of these circumstances, to maintain service quality and effective disaster response, a study on functional preparedness was conducted to assess the readiness level of these health centers. This study aimed to provide evaluation material for optimizing service quality. The research employed a quantitative analysis method, collecting numerical data to outline the preparedness level of the three health centers. The analysis results, achieved through manual calculations, indicated that Puskesmas Pakem exhibited the highest functional preparedness with a score of 0.45, categorized as "moderate." Puskesmas Turi scored 0.40, also categorized as "moderate." On the other hand, Puskesmas Cangkringan scored 0.24, falling into the "low" category. In conclusion, two health centers fell into the "moderate" category, indicating that their safety levels were operational during disasters. However, risks to the safety of staff and patients still persisted, necessitating future interventions. Meanwhile, one health center fell into the "low" category, signifying its inability to function optimally during disasters and therefore requiring immediate interventions.
Effects of Yacon Leaf Extract on MCP-1 and IL-10 Expressions and Macrophage Phenotypes in CKD Mouse Model Sofyana, Meida; Wasityastuti, Widya; Ihsana, Nuni; Purwono, Setyo; Arfian, Nur
Majalah Kedokteran Bandung Vol 56, No 2 (2024)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v56.3605

Abstract

Macrophages are essential in tissue homeostasis and immunity, but also contribute to disease development and progression. Chronic kidney disease (CKD) is characterized by interstitial infiltration of macrophages, the density of which correlates inversely with kidney survival. Studies have shown that yacon (Smallanthus sonchifolius) has beneficial effects on CKD. Therefore, this study aimed to investigate the effects of yacon leaf extract on mice with subtotal nephrectomy by evaluating the M1 and M2 macrophage counts and mRNA expressions of monocyte chemoattractant protein-1 (MCP-1 and IL-10. The mice were randomly divided into five groups: SO (negative control: underwent sham operation), SN (positive control: underwent subtotal nephrectomy), and yacon-treated groups: YK1, YK2, and YK3 (underwent subtotal nephrectomy, given peroral yacon leaf extract for 14 days with doses of 24,5 mg/kgBW/day, 49 mg/kgBW/day, and 98 mg/kgBW/day, respectively). The macrophage subtypes were assessed using immunohistochemistry anti-CD68 for M1 and anti-Arginase I for M2. MCP-1 and IL-10 mRNA expressions were analyzed using semi-quantitative PCR. Results showed that yacon leaf extract could significantly lower the M2 macrophage count (p<0.001) and the mRNA expressions of MCP-1 and IL-10 in all yacon-treated groups when compared to the SN group. However, the M1 macrophage count was only lower in the YK2 group (p=0.009). In conclusion, the administration of yacon leaf extract could attenuate kidney injury by lowering the macrophage count and the expression of MCP-1 and IL-10.
Co-Authors Alim, Ahmad Muttaqin Annisa Annisa Ario Tejosukmono Arliono, Tri Yunanto Budi Iftiyastuti, Selma Nissa Fadly M. Bima P Heriyanto, Mochammad Junaidy Hutomo, Muhammad Agita Indarto, Bayu Praditya murdiyanto, joko Nur Arfian, Nur Oktomi Wijaya Pamungkasih, Wahyu Putri, Rachma Greta Perdana Rizkita, Leonny Dwi Rokhmah, Budi Nur Selohandono, Andrianto Setyo Purwono Sofyana, Meida Widya Wasityastuti Yuniasih, Dewi