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All Journal E-Jurnal Medika Udayana J-Dinamika: Jurnal Pengabdian Kepada Masyarakat Makara Journal of Science Ahmad Dahlan Medical Journal Folia Medica Indonesiana
Putri, Rachma Greta Perdana
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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The Relationship between Nutritional Status and Menstrual Cycle among Medical Students at Ahmad Dahlan University Putri Dangga, Vathana Az Zahra; Putri, Rachma Greta Perdana; Rahmatullah, Irfan
E-Jurnal Medika Udayana Vol 13 No 4 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i04.P02

Abstract

Menstruation is the monthly shedding of the functional layer of the endometrium in the uterus that occurs when ovulation is not followed by fertilization. Menstrual irregularities occur due to hormonal disturbances caused by stress, excessive exercise, medication use, approaching menopause, eating disorders, and nutritional status such as underweight and obesity. Nutrition refers to the nutrients present in food that are required by the body to obtain energy for daily activities. Nutritional problems arise from an imbalance between the nutrients consumed and those needed by the body. To examine the relationship between nutritional status and menstrual cycles in students of the Faculty of Medicine, Ahmad Dahlan University, a research study was conducted using an observational analytical method with a cross-sectional approach. The research sample consisted of 131 students. Statistical analysis using chi-square analysis showed a p-value of 0.001, which is smaller than ? = 0.05. From these results, it can be concluded that there is a relationship between body mass index and upper arm circumference with the menstrual cycles of students in the Faculty of Medicine, Ahmad Dahlan University, while there is no relationship between waist circumference, waist-to-hip ratio, subcutaneous fat, and menstrual cycles in students of the Faculty of Medicine, Ahmad Dahlan University.
The Effect of Health Education on Knowledge of the Dangers of Smoking in Students of SMK Negeri 4 Yogyakarta Prisilla Maya Heni Pratiwi; Putri, Rachma Greta Perdana; Sukirto, Novi Wijayanti; Astuti, Fardhiasih Dwi
Ahmad Dahlan Medical Journal Vol. 5 No. 1 (2024): May 2024
Publisher : Universitas Ahmad Dahlan

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Abstract

Smoking is the activity of smoking tobacco rolls wrapped in paper or nipa leaves and then burning and producing smoke. In thesurvey results of the Ministry of Health of the Republic of Indonesia, the risk of smoking behavior in junior and senior high school students in Indonesia in 2015 was 32.82% in male students. Smoking habits lead to health risk for cardiovascular and respiratory diseases and many types of cancer. Smokers have moderate knowledge of tobacco. The study's aim is to examine the effect of health education on knowledge of the dangers of smoking in students of SMK Negeri 4 Yogyakarta. This study utilized a pre-experimental design method with One-Group Pretest-Posttest design approach. The study sample consisted of 127 students who met inclusion and exclusion criteria in class X students of SMK Negeri 4 Yogyakarta. The pretest and post-test scores varied from 22 to 29 with increased scores of the post-test’s trend. Statistical analysis using chi-square test analysis showed a p-value of 0.000 (<0.05). These results suggest that there is an influence between health education on knowledge of the dangers of smoking in students of SMK Negeri 4 Yogyakarta
Level of physical fitness of member of Indonesian Medical Association in Bantul, Yogyakarta Ihsana, Nuni; Yuniasih, Dewi; Putri, Rachma Greta Perdana; Annisa, Annisa; Tejosukmono, Ario; Heriyanto, Mochammad Junaidy; Pamungkasih, Wahyu; Rokhmah, Budi Nur; Murdiyanto, Joko
Ahmad Dahlan Medical Journal Vol. 5 No. 1 (2024): May 2024
Publisher : Universitas Ahmad Dahlan

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Abstract

Physical inactivity contributed to 7.2% of all-cause mortality. Many research demonstrates that the integration of physical activity and exercise into daily routine prevents chronic disease and lowers mortality. This study aims to assess the physical fitness of members of the Indonesian Medical Association in the Bantul region using a descriptive from secondary data. The subjects were 38 members of the Indonesian Medical Association. Physical fitness data was obtained using the Rockport One Mile Walking Test. Body Mass Index (BMI) is also calculated to describe excessive body fat. The majority of participants are female (52.63%) and participants dominant age ranged between 19 and 44 years old (50%). The participants aged 18 years old showed good physical fitness. The results in participants aged 19 to 44 years were more varied, there were 8 participants, 7 participants, 3 participants 1 participant had fair, good, poor, and very poor physical fitness, respectively. Physical fitness in participants aged 45 to 59 years were 9 and 5 participants showed good and fair physical fitness, respectively. The subjects aged >59 years old have 2 people with good physical fitness and 1 person with fair physical fitness. None of the participants with BMI status underweight, normal weight, or overweight showed poor physical fitness, while participants with obesity had poor and very poor physical fitness. Physical fitness is a multidimensional concept and is related to regular activity.
Pengenalan Makanan Halal dan Sehat Bagi Putra/Putri dari Pelajar dan Pekerja Migran di Lingkungan PCIA Taiwan: Making Halal-Healthy Food, Fun For Kids Septian Emma Dwi; Putri, Rachma Greta Perdana; Dewinta, Mustika Cahya Nirmala
J-Dinamika : Jurnal Pengabdian Masyarakat Vol 9 No 2 (2024): Agustus
Publisher : Politeknik Negeri Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25047/j-dinamika.v9i2.5024

Abstract

Perbedaan pola dan kebiasaan makan merupakan salah satu shock culture yang dihadapi oleh keluarga yang berpindah ke luar negeri untuk sekolah ataupun bekerja. Hal ini terjadi termasuk pada anak-anak yang mengikuti orangtuanya pindah ke luar negeri. Proses akulturasi pola makan yang dialami anak-anak tersebut dapat menyebabkan risiko obesitas dan penyakit kronis. Hal ini karena dipengaruhi perubahan fisik dan lingkungan baru. Disisi lain, kesibukan orangtua, juga bisa mempengaruhi keseimbangan asupan nutrisi makanan pada anak. Oleh karena itu, tim mengusulkan kegiatan pengabdian dengan tema pengenalan makanan sehat bagi anak-anak pelajar/pekerja migran di lingkungan PCIA Taiwan. Pelaksanaan kegiatan pengabdian dilakukan pada tanggal 1-2 Februari 2024 di Al-Hadi Taiwan Islamic Education & Culture Center, New Taipei City dengan sasaran anak-anak. Kegiatan berikutnya dilaksanakan secara online pada tanggal 7 Juni 2024 dengan sasaran para orangtua. Materi yang disampaikan dalam kegiatan ini meliputi pengenalan makanan sehat dan halal, adab makan dan minum dalam ajaran Islam, gangguan kesehatan yang berkaitan dengan makanan dan pencegahannya, peran orangtua dalam menghadapi shock culture perbedaan pola dan kebiasaan makan pada anak, dan praktik membuat makanan sehat dan memilih makanan halal.
Functional Disaster Preparedness at Community Health Centers in Mount Merapi Yogyakarta Disaster Prone Areas Arliono, Tri Yunanto; Putra, Fadly Muhammad Bima; Wijaya, Oktomi; Ihsana, Nuni; Indarto, Bayu Praditya; Hutomo, Muhammad Agita; Putri, Rachma Greta Perdana; Heriyanto, Mochammad Junaidy; Wijaya, Adi Indra; Alim, Ahmad Muttaqin
Ahmad Dahlan Medical Journal Vol. 5 No. 2 (2024): November 2024
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/admj.v5i2.10946

Abstract

Mount Merapi is one of the most active volcanoes in the world. The major eruptions happened in 1768, 1822, 1849, 1872, and the most recently in 2010. Three health centers are situated at the foot of Mount Merapi, with a high risk of potential disasters, ranging from eruptions and cold lava flows to landslides. To maintain service quality and effective disaster response, this study aimed to provide evaluation material for optimizing service quality and assessing the readiness level of these health centers. The research used a quantitative analysis method, collecting numerical data to outline the preparedness level of the three health centers: Puskesmas Pakem, Puskesmas Turi, and Puskesmas Cangkringan. The results, achieved through manual calculations, indicated that Puskesmas Pakem exhibited the highest functional preparedness with a score of 0.45, categorized as "moderate." Puskesmas Turi scored 0.40, also categorized as "moderate." On the other hand, Puskesmas Cangkringan scored 0.24, falling into the "low" category. In conclusion, two health centers fell into the "moderate" category, which means the risks to the safety of staff and patients persisted, necessitating future interventions. Meanwhile, one health center fell into the "low" category, signifying its inability to function optimally during disasters and requiring immediate interventions
Network Pharmacology and Molecular Docking Analysis of Nephelium lappaceum (Rambutan) Compounds as Potential Alternative Treatments for Lung Cancer Utami, Dwi; Farid, Muhammad; Putri, Rachma Greta Perdana
Makara Journal of Science Vol. 29, No. 3
Publisher : UI Scholars Hub

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Abstract

Introduction: Lung cancer is characterized by high mortality rates and poor prognosis, further requiring alternative therapies owing to the adverse effects of conventional chemotherapy. Rambutan (Nephelium lappaceum L.) has antimicrobial, antiproliferative, and antioxidant properties and can cure cancer. Method: Compounds from rambutan peel were identified through PubChem and analyzed for physicochemical properties using SwissADME. Target proteins were identified using SuperPred and compared with lung cancer–related proteins from GeneCards via Venny. Protein interactions were examined and visualized using STRING and Cytoscape, respectively. Protein activity was analyzed using WebGestalt, and docking simulations were performed using Autodock 4.2.6. Result: Physicochemical analysis of 10 active rambutan compounds via SwissADME showed favorable properties based on Lipinski’s rule, suggesting good oral bioavailability. In total, 276 specific target proteins were related to lung cancer. Cytoscape visualized the 53 core proteins implicated in lung cancer. Gene ontology and Kyoto Encyclopedia of Genes and Genomes analyses indicated that rambutan compounds are active in lung cancer pathways, particularly nonsmall cell lung cancer. The analysis identified the top 10 interacting proteins STAT3 and CASP3 had the highest interaction value of 28, followed by PIK3CA and NFKB1 at 22, MAPK3, PIK3R1, PTGS2, GRB2, MAPK1, and CASP8. Per docking simulations, 1,2-diphenylethane-1-ol was the highest affinity to STAT3 (−4.78) and CASP3 (−6.75). Conclusion: Rambutan peel compounds have remarkable anticancer potential, particularly with high affinity for STAT3 and CASP3 proteins, based on in silico molecular docking studies.
COMPARISON OF INTRAPERITONEAL AND INTRADUCTAL ROUTES IN THE GROWTH OF N-METHYL-N-NITROSOUREA-INDUCED BREAST CANCER IN SPRAGUE DAWLEY RATS: A SYSTEMATIC REVIEW 2014–2024 Prameswari, Adilla Soraya; Sompokan, Ruendhita Azzahra Sari; Annisa, Annisa; Putri, Rachma Greta Perdana; Yuniasih, Dewi; Danian, Muhamad; Tianotak, Muhammad Tri Yoga
Folia Medica Indonesiana Vol. 61, No. 2
Publisher : Folia Medica Indonesiana

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Abstract

Breast cancer is one of the[-6pc]AU: Please provide affiliations for your paper. leading causes of death for women worldwide, characterized by malignant tumors in the mammary epithelium. Breast cancer modelling using Sprague Dawley animals induced by N-Methyl-N-Nitrosourea (MNU) compounds is commonly used through various administration routes. The intraperitoneal route is the conventional route and the intraductal route is a new route capable of directly targeting the mammary ducts. Both routes affect the speed and characteristics of breast cancer cells in experimental animals. This systematic review using PubMed and Scopus databases from 2014-2024 aims to compare the effects of intraperitoneal and intraductal administration routes on breast cancer induction and the similarities in histopathological characteristics and biomarkers with human breast cancer cells. Of the 324 articles, 15 met the inclusion criteria showing that the intraductal route induces tumors faster (6–8 weeks) with Ductal Carcinoma In Situ (DCIS) type, ER+/PgR+ expression, and low Ki-67 index, resembling the luminal A subtype. The intraperitoneal route requires 8–12 weeks, producing multiple tumors with a high Ki-67 index, resembling luminal B. Administration of additional substances such as PF4, white tea, and physical activity are anti-tumorigenic, while radiation and a high-fat diet are pro-tumorigenic. Therefore, the intraductal route can be used as the main choice in selecting the route of administration of MNU induction.
Co-Authors Alim, Ahmad Muttaqin Annisa Annisa Ario Tejosukmono Arliono, Tri Yunanto Danian, Muhamad Dewinta, Mustika Cahya Nirmala Dwi Utami Fardhiasih Dwi Astuti Heriyanto, Mochammad Junaidy Hutomo, Muhammad Agita Ihsana, Nuni Indarto, Bayu Praditya Muhammad Farid murdiyanto, joko Oktomi Wijaya Pamungkasih, Wahyu Prameswari, Adilla Soraya Prisilla Maya Heni Pratiwi Putra, Fadly Muhammad Bima Putri Dangga, Vathana Az Zahra Rahmatullah, Irfan Rokhmah, Budi Nur Septian Emma Dwi Sompokan, Ruendhita Azzahra Sari Sukirto, Novi Wijayanti Tianotak, Muhammad Tri Yoga Wijaya, Adi Indra Yuniasih, Dewi