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Production of Starch-Based Bioplastic from Durio zibethinus Murr Seed Using Glycerol as Plasticizer Nanda Raudhatil Jannah; Novesar Jamarun; Yulia Eka Putri
Jurnal Riset Kimia Vol. 12 No. 2 (2021): September
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v12i2.398

Bioplastics are bio-based plastics from natural resources, made to replace conventional plastics. The utilization of biopolymers in bioplastics provide a faster degradation compared to petroleum-based plastics. Starch-based bioplastic from mixing Durio zibethinus Murr starch and glycerol as plasticizer have been conducted. In this research, the concentration of glycerol has been varied to study the effect on starch-based bioplastics mechanical properties. The tensile strength for Durio zibethinus Murr starch-based bioplastic with 20% glycerol was 50.28 MPa with 13.3% elongation. The functional group found on the Fourier transform infrared spectroscopy (FTIR) spectra indicated the presence of O-H stretch, C-H stretch, C=O stretch, and C-O stretch which stated the formation of bioplastic. The image results gained from scanning electron microscope (SEM) showed that the morphology surface of bioplastic was less homogenous and rough. The soil burial test for biodegradability showed Durio zibethinus Murr starch-based bioplastic achieved 38.9% weight loss in a 5-day observation.

The Effect of Various Concentrations of the Addition of Emulsifier Tween 80 and Span 80 on the Stability of Cream Formulation Ethanolic Extract of Basil Leaves (Ocimum Americanum L) Fitria Wulandari; Fauzia Ningrum Syaputri; Nanda Raudhatil Jannah
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 3, No 2 (2022): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v3i2.8257

ABSTRAKThis study aims to determine the effect of the various concentration of the addition of emulsifier tween 80 and span 80 on the stability of cream preparations containing ethanolic extract of basil leaves (Ocimum americanum L) before and after the freeze-thaw cycling test. The formulation of the cream preparation uses 3 of emulsifier concentrations tween 80 and span 80 (1%, 3%, 5%). The evaluation tests carried out were organoleptic, pH, viscosity, spreadability, adhesion, centrifugal test, emulsion type, homogeneity and freeze-thaw cycling. The results of several tests for the three formulations before and after the freeze-thaw cycling test at temperatures (2-8˚C) and (15-30˚C) for 24 hours, for 3 cycles, such as pH, dispersion, adhesive, and viscosity met the requirements for cream formulation. It has pH 5-5.10, dispersion test 5.1-5.8 cm, adhesiveness test 06.05-06.65 seconds and viscosity test increased significantly with a value range of 2000-30000 cPs. Except, for the centrifugal test of formula 1 because of the separation cream phase. This study concludes that the results of statistical tests analyzed using ANOVA showed no significant difference in the addition of emulsifier tween 80 and span 80 in three variations of cream dosage concentrations before and after freeze-thaw cycling for 3 cycles. Kata kunci : Kemangi; Krim; Emulgator; Span; Tween ABSTRACTPenelitian ini bertujuan untuk mengetahui pengaruh konsentrasi penambahan emulgator tween 80 dan span 80 terhadap stabilitas sediaan krim ekstrak etanol daun kemangi (Ocimum americanum L) sebelum dan sesudah uji freeze-thaw cycling. Formulasi sediaan krim menggunakan 3 konsentrasi emulgator tween 80 dan span 80 yaitu (1%, 3%, 5%). Uji evaluasi yang dilakukan adalah uji organoleptik, pH, viskositas, daya sebar, daya lekat, uji sentrifugal, tipe emulsi, homogenitas dan freeze-thaw cycling. Hasil pengujian ketiga formulasi sebelum dan sesudah uji freeze-thaw cycling pada suhu (2-8˚C) dan (15-30˚C) selama 24 jam 3 siklus seperti pH, daya sebar, daya lekat, dan viskositas memenuhi persyaratan. Hasil untuk Uji pH 5-5,10, uji daya sebar 5,1-5,8 cm, uji daya lekat 06,05-06,65 detik dan uji viskositas yang meningkat signifikan untuk formula 1, 2 dan 3 dengan kisaran nilai 2000-30000 cPs. Kecuali, uji sentrifugal formula 1 terjadi pemisahan fase krim. Penelitian ini menyimpulkan bahwa hasil uji statistik di analisis menggunkan ANOVA menunjukan tidak adanya perbedaan yang bermakna pada penambahan emulgator tween 80 dan span 80 pada tiga konsentrasi sediaan krim sebelum dan sesudah freeze-thaw cycling selama 3 siklus. Keywords : Basil; Cream; Emulsifier; Span; Tween.

ANALISIS KANDUNGAN TIMBAL DAN MERKURI DALAM LIPSTIK YANG DIGUNAKAN OLEH MAHASISWI UNIVERSITAS MUHAMMADIYAH BANDUNG: ANALYSIS OF LEAD AND MERCURY LEVELS IN LIPSTICK USED BY STUDENTS OF MUHAMMADIYAH UNIVERSITY BANDUNG Nurul Ambardhani; Nadhila Zakiya Raharja; Nanda Raudhatil Jannah
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 1 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i1.567

Lipstik termasuk salah satu jenis kosmetik yang paling banyak digunakan oleh wanita Indonesia. Penggunaan lipstik bertujuan untuk mempertahankan penampilan pengguna dan memberi warna pada bibir sehingga tidak terlihat pucat. Bahan dasar lipstik terdiri dari bahan alami dan sintesis serta adanya penambahan logam berat untuk menunjang daya tahan dan kinerja produk. Logam berat yang biasa ditambahkan yaitu timbal (Pb) dan merkuri (Hg). Penelitian ini bertujuan untuk menganalisis kandungan Pb dan Hg dalam lipstik yang digunakan oleh mahasiswi Fakultas Sains dan Teknologi, Universitas Muhammadiyah Bandung dan menentukan apakah kandungan logam tersebut berada pada batas aman yang telah ditetapkan. Lima lipstik dianalisis secara kualitatif dan kuantitatif. Pengamatan kualitatif secara organoleptis dan menggunakan reagen KI 0,5N; NaOH 2N; dan HCl 37%. Hasil analisis kualitatif menunjukkan lipstik 1, 2, 3, dan 5 mengandung Pb serta lipstik 1, 2, dan 5 mengandung Hg. Analisis kuantitatif menggunakan spektrofotometer serapan atom menunjukkan lipstik mengandung Pb dan Hg dengan masing-masing konsentrasi pada rentang 0,0300-0,1000 ppm dan 0,0021-0,0049 ppm. Kelima lipstik yang dianalisis mengandung Pb dan Hg tidak melebihi batas yang telah ditetapkan BPOM RI, yaitu 20 dan 1 ppm. Kata kunci : lipstik, logam Pb, logam Hg, spektrofotometer serapan atom

QUALITATIVE AND QUANTITATIVE ANALYSIS OF HYDROQUINONE CONTENT IN MARKETPLACE FACIAL WHITENING CREAMS Zaman Ruchiyat; Nanda Raudhatil Jannah; Ayu Shalihat
Chimica Didactica Acta Vol 11, No 1: June 2023
Publisher : FKIP USK

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jcd.v11i1.32162

Hydroquinone is one of the dangerous ingredients in facial whitening cream cosmetics which can cause skin irritation, skin redness and a burning feeling. The purpose of this study was to determine the hydroquinone content in facial whitening cream cosmetics sold in the marketplace. The method used in this study was a qualitative test using a colour reagent test and the Thin Layer Chromatography (TLC) method with toluene:glacial acetic acid as the mobile phase (5:5) and Silica Gel254 Plate as the stationary phase. Quantitative analysis used the UV Vis spectrophotometry method at a wavelength of 541 nm. The results of the qualitative test in the TLC test showed that 4 samples tested positive for hydroquinone in samples A, B, D, and E, with a range of Rf values of 0.44, 0.5, 0.52, and 0.5, respectively. The results of the quantitative test showed that 9 samples contained hydroquinone with a sample content range of 0.22 to 3.62 ppm with an LoD value of 0.637 ppm and an LoQ of 2.124 ppm. The results of this study indicate that there are still cosmetics containing hydroquinone, these results are not following the Regulation of Badan Pengawas Obat dan Makanan (BPOM) No. KH. 00.01.43.2503 of 2009 where the use of this hydroquinone ingredient is prohibited for use in facial whitening creams because it can endanger health.Keywords: Analysis, Hydroquinone, TLC, Whitening Cream

ANALISIS KANDUNGAN TIMBAL DAN MERKURI DALAM LIPSTIK YANG DIGUNAKAN OLEH MAHASISWI UNIVERSITAS MUHAMMADIYAH BANDUNG: ANALYSIS OF LEAD AND MERCURY LEVELS IN LIPSTICK USED BY STUDENTS OF MUHAMMADIYAH UNIVERSITY BANDUNG Nurul Ambardhani; Nadhila Zakiya Raharja; Nanda Raudhatil Jannah
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 1 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i1.567

Lipstik termasuk salah satu jenis kosmetik yang paling banyak digunakan oleh wanita Indonesia. Penggunaan lipstik bertujuan untuk mempertahankan penampilan pengguna dan memberi warna pada bibir sehingga tidak terlihat pucat. Bahan dasar lipstik terdiri dari bahan alami dan sintesis serta adanya penambahan logam berat untuk menunjang daya tahan dan kinerja produk. Logam berat yang biasa ditambahkan yaitu timbal (Pb) dan merkuri (Hg). Penelitian ini bertujuan untuk menganalisis kandungan Pb dan Hg dalam lipstik yang digunakan oleh mahasiswi Fakultas Sains dan Teknologi, Universitas Muhammadiyah Bandung dan menentukan apakah kandungan logam tersebut berada pada batas aman yang telah ditetapkan. Lima lipstik dianalisis secara kualitatif dan kuantitatif. Pengamatan kualitatif secara organoleptis dan menggunakan reagen KI 0,5N; NaOH 2N; dan HCl 37%. Hasil analisis kualitatif menunjukkan lipstik 1, 2, 3, dan 5 mengandung Pb serta lipstik 1, 2, dan 5 mengandung Hg. Analisis kuantitatif menggunakan spektrofotometer serapan atom menunjukkan lipstik mengandung Pb dan Hg dengan masing-masing konsentrasi pada rentang 0,0300-0,1000 ppm dan 0,0021-0,0049 ppm. Kelima lipstik yang dianalisis mengandung Pb dan Hg tidak melebihi batas yang telah ditetapkan BPOM RI, yaitu 20 dan 1 ppm. Kata kunci : lipstik, logam Pb, logam Hg, spektrofotometer serapan atom

Fomulasi Sediaan Krim Minyak Atsiri Serai Wangi (Cymbopogon Nardus L. Rendle) dengan perbedaan konsentrasi emulgator Syaputri, Fauzia Ningrum; Anzaina Sukmawati; Nanda Raudhatil Jannah; Dwintha Lestari; Tugon, Titian Daru Asmara; Wulandari, Fitria
FARMASIS: Jurnal Sains Farmasi Vol 4 No 2 (2023): Vol. 4 No 2 (2023): Farmasis: Jurnal Sains Farmasi
Publisher : Universitas PGRI Adi Buana, Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/farmasis.v4i2.7554

Latar belakang: Salah satu penyakit kulit adalah jerawat (acne vulgaris) dan bakteri yang umum menjadi penyebab jerawat yaitu Propionibacterium acne. Tanaman yang dapat digunakan sebagai anti bakteri penyebab jerawat yaitu serai wangi (Cymbopogon nardus L. Rendle), serai wangi memiliki kandungan kimia flavanoid dan banyak terkandung citronelal. Mnyak serai wangi (Cymbopogon nardus L. Rendle) dibuat dalam sediaan krim sehingga mudah untuk digunakan dan konsentrasi yang digunakan adalah 2,09 persen. Tujuan: Untuk menentukan perbedaan pengaruh konsentrasi emulgator asam stearat F1, F2, F3 (3 persen, 2,5 persen, 1,5 persen) dan trietanolamin F1, F2, F3 (2 persen, 3 persen, 4 persen) terhadap stabilitas krim mengandung minyak atsiri serai wangi sebelum dan setelah freeze thaw. Metode: evaluasi yang dilakukan yaitu cycling test dengan beberapa parameter uji seperti uji organoleptis, uji homogenitas, , uji viskositas, uji pH, uji daya sebar, uji daya lekat dan uji tipe krim. Hasil: F3 merupakan formula yang memiliki stabilitas paling baik setelah dilakukan evaluasi freeze thaw dengan karakteristik sediaan tekstur semi solid, warna putih kekuningan, bau khas minyak serai wangi, memiliki pH 6,03, daya sebar 6.8 cm, serta daya lekat 6,29 detik dan membentuk tipe M/A. memiliki sifat alir pseudoplastis tiksotropik dengan viskositas 4.000-40.000 cPs (seluruh pengujian pengambilan data dengan metode 3 replikasi). Variasi konsentrasi emulgator memberikan perbedaan pada hasil pH semakin banyak trietanolamin maka semakin basa sediaan pada dan mempengaruhi hasil daya sebar. Kesimpulan: Dari seluruh hasil uji evaluasi dapat disimpulkan bahwa formula 3 memiliki kestabilan yang optimal dengan konsentrasi asam stearat 1,5 persen dan trietanolamin 4 persen.

Nanometer-Scale Drug Synthesis: Innovations in Pharmaceutical Nanotechnology Fajriyah, Maulida; Nurjannah, Neng Rita; Ambardhani, Nurul; Jannah, Nanda Raudhatil
INFLUENCE: INTERNATIONAL JOURNAL OF SCIENCE REVIEW Vol. 6 No. 1 (2024): INFLUENCE: International Journal of Science Review
Publisher : Global Writing Academica Researching and Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar

Nanometer-scale drug development represents a new era in pharmaceutical technology, promising significant improvements in the efficacy and safety of treatments. Nanotechnology innovations in drug synthesis offer the potential to address existing global health challenges, including drug resistance and difficult-to-treat chronic diseases. However, the synthesis process at the nanometer scale faces significant obstacles, including biocompatibility issues, unclear regulations, and technical challenges in production. This research aims to explore and identify strategies to overcome these challenges, as well as assess the potential of nanotechnology innovation in the development of new drugs. The research method used is a descriptive qualitative approach, with data sourced from relevant previous literature. The data collected is then processed to gain an in-depth understanding of the research subject. The conclusions of this study indicate that although the challenges in nanometer-scale drug synthesis are significant, the potential for nanotechnology innovation in pharmaceuticals is revolutionary. Effective strategies to overcome these challenges include the development of new synthesis methods, advances in characterization techniques, and close interdisciplinary collaboration. Policies and regulations that support innovation are urgently needed to facilitate the development and implementation of these new medicines. Finally, the future of nanometer-scale medicine depends on increasing access and desirability, taking into account ethics and safety in product development.

Peningkatan Pengetahuan Jajanan Sehat melalui Penyuluhan dan Demonstrasi Deteksi Bahan Kimia Berbahaya Makanan pada Anak Usia Sekolah: Increasing Knowledge of Healthy Snacks through Counseling and Demonstration of Detection of Food Harmful Chemicals in School-Age Children Rahman, Adam Aulia; Jannah, Nanda Raudhatil; Setyaningrum, Dwi Larasati; Firdaus, Wahyu Alfath; Husnaini, Rovi
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 8 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i8.9961

The use of harmful food chemicals in snacks for schoolchildren remains a widespread issue. Each year, BPOM (the Indonesian Food and Drug Authority) identifies the presence of formaldehyde, borax, and food additives that exceed permissible levels in snack foods. School snacks are essential as they provide energy and vital nutrients for children. However, unhealthy snacks containing dangerous chemicals can impede optimal growth and development, potentially leading to various health issues. This community service, funded by an internal grant from Universitas Muhammadiyah Bandung, aims to educate children about healthy snacks through outreach activities and detecting harmful food chemicals. Pretest and posttest data were collected from 43 children from elementary to junior high school in RW 02 Cipadung Kidul, Panyileukan, Bandung. The results indicate a significant increase in the children's understanding of healthy snacks and harmful food chemicals. Initially, they answered an average of 44.76% of questions correctly. After participating in the program, this number rose to 93.81%. This increase in knowledge indicates that educational outreach, combined with demonstrations on detecting harmful food chemicals, effectively engages children and enhances their understanding of the material presented.

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