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All Journal Indonesian Journal of Chemistry Jurnal Layanan Masyarakat (Journal of Public Service) Journal of Bio-molecule Research And Engineering
Takaya, Yoshiaki
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Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Environmental Science Immunology & microbiology Social Sciences Other

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Chemotaxonomic Relationship of Oligomer Resveratrol in Three Malaysian Dipterocarpus Species from the Taxonomic Tribe of Dipterocarpaceae Nawi, Liliwirianis; Zain, Wan Zuraida Wan Mohd; Ahmat, Norizan; Osman, Che Puteh; Takaya, Yoshiaki; Kamarozaman, Aisyah Salihah; Adnan, Noorazlina; Azahar, Siti Zakirah
Indonesian Journal of Chemistry Vol 24, No 3 (2024)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.82848

Abstract

A phytochemical investigation of three species of Malaysian Dipterocarpus contributed to the isolation of 22 compounds which consist of 15 oligostilbenoids, 2 terpenes, 2 coumarins, and 3 flavonoids. The isolation of flavonoids in the Dipterocarpaceae family is very limited. Moreover, 4-methoxepigallocatechin-3-O-O-(3-methyl) gallate (20) was isolated for the first time in the plant. The occurrence of 4-O-methylgallocatechin (18) and its stereoisomer; 4-O’-methylepigallocatechin (19) was first reported in the Dipterocarpaceae family. This study also reported the existence of several types of oligostilbenoids such as davidiol A (8), stenophyllol B (9), isohopeaphenol (11), resveratrol (1), and ampelopsin E (10) which are the first occurrence in Dipterocarpus genus and suggested a significant chemotaxonomic relationship between Dipterocarpus, more closely to Vatica which is classified under Dipterocarpeae tribe.
The comparative of free energy binding between Pyrimethamine-pDHFR double mutant and Pyrimethamine-pDHFR quadruple mutant: Structure-based approach Abdjan, Muhammad Ikhlas; Aminah, Nanik Siti; Kristanti, Alfinda Novi; Takaya, Yoshiaki; Siswanto, Imam
Journal of Bio-Molecule Research and Engineering Vol 1 No 2 (2022)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbiome.v1i2.43982

Abstract

Structure-based was performed to understand the mechanism inhibition of pyrimethamine (CP6) against Plasmodium Falciparum mutants at the molecular level. A molecular docking process was carried out to obtain the initial conformation of each system. The data showed in the form of RMSD values, hydrogen bonds, and grid scores. The results show that the RMSD value in the redocking process meets the criteria of the CP6-1J3J and WRA-1J3K complexes with a value of ≤ 2 í…. Several hydrogen bonds bind to receptor-active sites, including Ile14, Asp50, Ile164, and Asn108. Additionally, the grid score (kcal/mol) binds well on the active site: CP6-1J3J (-46.86), WRA-1J3K (-65.40), and CP6-1J3k (-44.71). Furthermore, molecular dynamics simulation was carried out to determine the free energy (∆Gbind) of each complex using the MM/GBSA approach. The results show ∆Gbind (kcal/mol) in each complex, namely CP6-1J3J (-28.24), WRA-1J3K (-36.62), and CP6-1J3k (-24.23). Information on this research was expected to provide molecular insight into pyrimethamine as an antimalaria inhibitor.
TRAINING ON FOOD PACKAGING FOR MSMEs SENDEN VILLAGE TRENGGALEK BY UNAIR TEAM & PARTNER UNIVERSITIES Aminah, Nanik Siti; Kristanti, Alfinda Novi; Ramadhan, Rico; Hendradi, Rimuljo; Takaya, Yoshiaki; Khoso, Mir Hasan; Baharin, Siti Nor Atika; Abdjan, Muhammad Ikhlas
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 9 No. 2 (2025): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/.v9i2.2025.238-248

Abstract

The International Community Services program (ICS) at Universitas Airlangga, part of the Tri Dharma of the university focusing on community service, aims to enhance human resource capacities within communities. In 2024, the program targeted Senden Village, Kampak sub-District, Trenggalek District, East Java, Indonesia, to assist its MSMEs in overcoming packaging challenges that hinder market interest. Collaborating with domestic and international universities, including Universitas Mayjen Sungkono, SMBBMU University Larkana Pakistan, UiTM Negeri Sembilan Malaysia, UM Malaysia, and Meijo University Japan, the program provided intensive training on innovative and functional packaging techniques. This program was chosen and considered urgent because processed food products produced by local MSMEs are still sold in bulk and packaged haphazardly. Therefore, a touch of hygienic and "eye-catching" packaging technology is needed. Attractive and hygienic packaging technology is expected to increase the selling power of these processed food products. The training included theoretical sessions, focus group discussion (FGD) demonstrations, and the introduction of plastic vacuum sealers to improve product packaging and branding. Food packaging workshop held on July 15, 2024, where participants engaged in hands-on training, group discussions, and label design, resulting in tangible improvements in product marketability. The initiative of this activity is not only to increase the visibility and attractiveness of Senden Village products but also to introduce the natural exotism of the village and local products to the national and international community, encouraging cultural and knowledge exchange. The collaboration of this program strengthens international collaboration and provides invaluable experience for students and lecturers. The successful implementation of this program confirms Airlangga University's commitment to community service and its goal of creating a sustainable positive impact on the village community, which ultimately contributes to the development of better human resources. The training has been carried out very well and each training participant has their own brand with an attractive logo and is hygienically packaged with vacuum technology. All training participants were satisfied with this activity as well as head of village, head of PKK, and all the team involved. They hope that next year's activities can be carried out with other innovations for the progress of Senden village.
Co-Authors Abdjan, Muhammad Ikhlas Adnan, Noorazlina Ahmat, Norizan Alfinda Novi Kristanti Azahar, Siti Zakirah Baharin, Siti Nor Atika Imam Siswanto Kamarozaman, Aisyah Salihah Khoso, Mir Hasan Nanik Siti Aminah Nawi, Liliwirianis Osman, Che Puteh Rico Ramadhan, Rico Rimuljo Hendradi Zain, Wan Zuraida Wan Mohd