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All Journal HAYATI Journal of Biosciences Journal of Food and Pharmaceutical Science Jurnal Matematika & Sains Indonesian Journal of Tropical and Infectious Disease UNEJ e-Proceeding Jurnal Kimia Riset Indonesian Journal of Chemistry Jurnal Layanan Masyarakat (Journal of Public Service) Journal of Food and Pharmaceutical Sciences Bulletin of Chemical Reaction Engineering & Catalysis Journal of Bio-molecule Research And Engineering Andan Jejama: Indonesian Journal Of Community Engagement
Nanik Siti Aminah
Departemen Kimia, Fakultas Sains Dan Teknologi, Universitas Airlangga
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Laevifonol, Diptoindonesin A, dan Ampelopsin A, Tiga Dimer Stilbenoid dari Kulit Batang Shorea seminis V. Sl. (Dipterocarpaceae) Nanik Siti Aminah; Sjamsul Arifin Achmad; Euis Holisotasn Hakim; Yana Maolana Syah; Lia Dewi Juliawaty; Emilia L. Ghisalberti
Jurnal Matematika & Sains Vol 8, No 1 (2003)
Publisher : Institut Teknologi Bandung

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Abstract

Laevifonol (1), a dimer stilbenoid, namely a hybrid between ε-viniferin and ascorbic acid had been isolated from ethyl acetate extract of the stem bark of Shorea seminis V.Sl. The structure of this compound was determined on the basis of spectroscopic data.
ANTIOXIDANT ACTIVITY OF METHANOL EXTRACTS FROM THE STEM BARK OF MANGROVE PLANT Rhizophora mucronata Mahmiah Mahmiah; Giman Giman; Nanik Siti Aminah; Mulyadi Tanjung
UNEJ e-Proceeding Proceeding of 1st International Conference on Medicine and Health Sciences (ICMHS)
Publisher : UPT Penerbitan Universitas Jember

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Abstract

Numbers of diseases such as stroke, diabetes, gout,and even cancer are caused by the reaction of freeradicals (oxidants) found in the body. Those diseasescurrently have not yet controlled. Deleteriouslifestyle, lack of exercise, or genetics can be thetrigger to this oxidant. Based on Chemotaxonomic,drugs that have been used to inhibit the oxidationprocess or termination stage of free radicals containthe active ingredient in the form of secondarymetabolites of alkaloids, phenolics, terpenoids andsteroids. For example, phenolic compounds such asflavonoids, xanthones, antioxidants and polyphenolsis a good agent because it has a structure with a highdegree of oxidation (Suares, et al, 2010).Researches related to the exploration of antioxidantactive ingredient has been more focused onsecondary metabolites found in terrestrial plants.The development of natural compounds potential ofmarine plant material such as mangrove are still notreceived much attention. Spalding et al. in 2001explained that mangroves plant in Indonesia is thehighest in the world, both in terms of quantity area(± 42 550 km2) as well as the number of species (±45 species). This basic natural resource of Indonesiamangrove is certainly valuable promisingopportunities to be expanded as a biological drug.Mangroves plant that commonly used as medicinediscovered from various species i.e: Acanthusilicifolius, Avicennia alba, Avicennia marina,Avicennia offinalis, Bruguiera cylindrical, Bruguieraexaristata, Bruguiera gymnorrhiza, Ceriops tagal,Hisbiscus tiliaceus, Ipomoea pes-capre, Lumnitzeraracemosa, Nypa fructicans, Pluchea indicaRhizophora apiculata, Rhizophora mucronata andSonneratia alba. Those plants are usually utilized asantiasma, antidiuretic, antidiabetic, reliever itching,and others. (Purnobasuki, 2004).The potential of mangroves as a drug is veryimportant to be developed considering the need fordrugs is increasing deals with the growing ofpopulation and many kinds of diseases such ascancer, hypertension, tumor diseases and diseasescaused by chemical or biological waste pollutionfrom viruses and bacteria. People are more likely tochoose drugs that are natural because relatively takefew side effects or even none at all.Several studies of mangrove plants from genusRhizophora that have antioxidant bioactivity areshown in the crude butanol extract of mangrove R.apiculata with IC50 33.34 pg / mL (Gao, 2012). Themethanol extract of R. mangle’s stem were alsodocumented to have antioxidant activity (Palacio, etal, 2014).One of mangroves found in Surabaya East Coastal(Pamurbaya), East Java, Indonesia is the mangroveRhizophora mucronata. This mangrove species isindigenous mangroves that ethno-botanicallypopular used as a pain reliever and dyes naturalwood. Secondary metabolites contained in theleaves, bark, stems, roots, and fruit are different inquantity. The content of secondary metabolites inplant commonly used as a medicine is from generalpart of the bark. Therefore, on the basis ofchemotaxonomic and ethno-botany of mangroves R.mucronata, this study aims to explore the bioactivityof antioxidant from the stem bark of R. mucronata.
Skopoletin Senyawa Fenilpropanoid dari Kulit Umbi Ubi Jalar (Ipomoea batatas L.) varietas IR-melati Citra Putri Pramitha; Nanik Siti Aminah; Alfinda Novi Kristanti
Jurnal Kimia Riset Vol. 1 No. 2 (2016): Desember
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (275.816 KB) | DOI: 10.20473/jkr.v1i2.3087

Abstract

AbstrakTelah berhasil diisolasi senyawa golongan fenilpropanoid dengan nama “skopoletin” dari kulit umbi ubi jalar (Ipomoea batatas L.). Ekstraksi senyawa dilakukan dengan metode maserasi menggunakan pelarut metanol, dilanjutkan dengan partisi menggunakan n-heksana dan etil asetat. Pemisahan dan pemurnian senyawa dilakukan menggunakan teknik kromatografi kolom gravitasi. Struktur senyawa dianalisis berdasarkan data spektroskopi UV/Vis, 1D, dan 2D-NMR. Kata kunci : fenilpropanoid, skopoletin, Ipomoea batatas L. AbstractIt has been isolated phenylpropanoid group compound named scopoletin from the tuber peel of Ipomoea batatas L. Extraction of this compound was done by maceration method using methanol solvent, followed by partition with n-hexane and ethyl acetate. Separation and purofication of compound was done by gravity column chromatography techniques. Structure of compound was analyzed by UV/Vis, 1D and 2D NMR spectroscopies. Keywords : phenylpropanoid, scopoletin, Ipomoea batatas L.
4-ETOKSI-3-METOKSIFENOL DAN METIL-3,4-DIHIDROKSIBENZOAT, DUA SENYAWA TURUNAN FENOLIK DARI EKSTRAK ETIL ASETAT KULIT UMBI GADUNG (Dioscorea hispida Dennst) DAN AKTIVITAS ANTIOKSIDAN EKSTRAK ETIL ASETAT Nanik Siti Aminah; Alfinda Novi Kristanti; Qonitah Labibah; Ana Firdausyah; Yoshiaki Takaya
Jurnal Kimia Riset Vol. 3 No. 1 (2018): Juni
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (761.177 KB) | DOI: 10.20473/jkr.v3i1.8873

Abstract

Two phenolic compoundnamely 4-ethoxy-3-methoxyphenol and methyl-3,4-dihydroxybenzoic have been isolated fromDioscorea hispida Dennst. The isolation of phenolic compounds was done by maceration methods using methanol, followed by partition with n-hexane and ethyl acetate. The process of separation and purification used various chromatography techniques including vacuum liquid chromatography, column chromatography, and radial chromatography. The structure of isolated compounds were determined by spectroscopic methods including UV-Vis, IR, 1D and 2D NMR. The ethyl acetate extract was evaluated for DPPH free radical scavenging activity assay. The IC50of ethyl acetate extract was 415 ppm. The result of this assay indicated that ethyl acetate extract has a potential as an antioxidant.  Keywords: Dioscorea hispida Dennst, Dioscoreaceae, phenolic, 4-ethoxy-3-methoxyphenol, methyl-3,4-dihydroxybenzoic, and antioxidant
SKOPOLETIN SUATU SENYAWA FENILPROPANOID DARI EKSTRAK ETIL ASETAT UMBI UBI JALAR (Ipomoea batatas L.) Nanik Siti Aminah; Choirotul Isma; Alfinda Novi Kristanti
Jurnal Kimia Riset Vol. 3 No. 2 (2018): Desember
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (418.964 KB) | DOI: 10.20473/jkr.v3i2.12061

Abstract

AbstrakTelah berhasil diisolasi senyawa golongan fenil propanoid  dengan nama “skopoletin” dari ekstrak etil asetat  umbi Ubi Jalar (Ipomoea batatas L.). Ekstraksi senyawa fenolik dilakukan dengan metode maserasi menggunakan pelarut metanol, dilanjutkan partisi menggunakan n-heksana dan etilasetat. Pemurnian dilakukan dengan kromatografi kolom gravitasi dan ktomatografi radial menghasilkan senyawa golongan fenil propanoid. Struktur skopoletin diidentifikasi berdasarkan data spektrum UV, 1D dan 2D NMR.Kata kunci : fenil propanoid, skopoletin, dan Ipomoea batatas L. AbstractPhenylpropanoid group compound has been isolated as “scopoletin” from ethylacetate extract of tuber flesh Sweet potatoes (Ipomoea batatas L.). Extraction of phenolic compound was done by maceration method using methanol solvent, then partition with n-hexana and  ethylacetate, respectively. The process of purification using various chromatographic techniques yielded compound of phenylpropanoid group. Structure of scopoletin is identified based on UV, 1D, and 2D NMR spectra.Keyword  : phenyl propanoid, scopoletin, dan Ipomoea batatas L.
PENDAMPINGAN PEMBERDAYAAN HASIL LAUT KEPADA ISTRI NELAYAN PANTAI SINE DESA KALIBATUR, KECAMATAN KALIDAWIR, KABUPATEN TULUNGAGUNG Nanik Siti Aminah; Tio Christiawan Bramayudha; Marisa Nur Shahadatin; Khusnul Wardah Mukharomah; Alsya Firdausi Nuzula; Azalea Rahma Septianti; Mochamad Zakki Fahmi; Satya Candra Wibawa Sakti; Nurina Fitriani; Nita Citrasari; Rimuljo Hendradi; Taufik Taufik; Ganden Suprianto
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 5 No. 2 (2021): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jlm.v5i2.2021.390-399

Abstract

AbstractThe seawater fishery in Dusun Sine has the higher potentials, due to its location near the coastal area of Sine Beach. In general, the people in Dusun Sine make a living as sea fishermen. However, the income of the marine fishing community has not maximized because the community still uses the conventional marine product processing production system, so that the marketing of processed marine fish products is also limited. As an effort to increase the selling value of processed marine fish, the International Community Service Group empowers fishermen's wives in Sine Hamlet by conducting several activity programs in the form of socializing the manufacture of modern marine processed products in the form of Sine Foodies, home industry food (PIRT), and the use of e-commerce. This activity was held to use a health protocol and through a presentation method on product marketing licensing in the form of PIRT socialization and marketing of processed marine fish products with e-commerce as well as demonstrations on the process of making processed marine fish products in the form of shredded fish and fish balls using attractive packaging. Participants in the socialization were fishermen's wives, village cadres, and prospective entrepreneurs from Kalibatur Village.Keywords: Assistance, processed marine fish products, Processing, Licensing management, MarketingAbstrakSektor perikanan air laut yang ada di Dusun Sine, Desa Kalibatur, Kecamatan Kalidawir, Kabupaten Tulungagung, memiliki potensi yang sangat tinggi. Hal ini disebabkan letaknya yang berada di dekat wilayah pesisir Pantai Sine. Secara umum, masyarakat di Dusun Sine bermata pencaharian sebagai nelayan laut. Namun, pendapatan masyarakat nelayan laut belum maksimal karena masyarakat masih menggunakan sistem produksi pengolahan hasil laut secara konvensional, sehingga pemasaran produk hasil olahan ikan laut juga terbatas dengan seadanya. Sebagai upaya untuk meningkatkan nilai jual hasil olahan ikan laut, Tim Pengabdian masyarakat Departemen Kimia, Fakultas Sains dan Teknologi, Universitas Airlangga dengan didukung penuh oleh Kelompok mahasiswa KKN Internasional, FST, UNAIR melakukan upaya pemberdayaan para istri nelayan di Dusun Sine dengan melakukan beberapa program kegiatan berupa sosialisasi pembuatan hasil olahan laut secara modern berupa Sine Foodies, pangan industri rumah tangga (PIRT), serta penggunaan e-commerce. Kegiatan ini diselenggarakan menggunakan protokol kesehatan dan melalui metode presentasi mengenai perijinan pemasaran produk berupa sosialisasi PIRT dan pemasaran produk hasil olahan ikan laut dengan e-commerceserta demonstrasi mengenai proses pembuatan produk hasil olahan ikan laut yang berupa abon ikan dan bakso ikan dengan menggunakan kemasan yang menarik. Peserta sosialisasi adalah para istri nelayan, kader desa, dan calon pengusaha yang berasal dari Dusun Sine, Desa Kalibatur. Kata Kunci: Pendampingan, Produksi makanan olahan hasil laut, Pengurusan perijinan, Pemasaran 
(-)-AMPELOPSIN A : A DIMER RESVERATROL FROM Dryobalanops oblongifolia (dipterocarpaceae) Nanik Siti Aminah; Sjamsul Arifin Achmad; Masatake Niwa; Yana Maolana Syah; Euis Holisotan Hakim
Indonesian Journal of Chemistry Vol 6, No 1 (2006)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (227.094 KB) | DOI: 10.22146/ijc.21778

Abstract

A dimer resveratrol compound named (-)-ampelopsin A was isolated from acetone extract of the stem bark of  Dryobalanops oblongifolia (Dipterocarpaceae). The structure of this compound was determined on the basis of NMR spectroscopic data.
Design of Catechin-based Carbon Nanodots as Facile Staining Agents of Tumor Cells Yaung Kwee; Alfinda Novi Kristanti; Nanik Siti Aminah; Mochamad Zakki Fahmi
Indonesian Journal of Chemistry Vol 20, No 6 (2020)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.50327

Abstract

Carbon nanodots (CNDs) have widely received great attention as a result of favorable optical, electrical, optoelectrical, biocompatible, and non-toxic properties these nanoparticles possess. However, the exploration of nanoparticle from natural raw material was limited. In present work, the carbon dots were produced from catechin isolated from Uncaria gambir through a simple and facile process. Carbon nanodots were further produced by the pyrolysis process of catechin, which allowed it for carbonization. Owing to its unique properties such as photoluminescence with an emission peak at 500 nm (lex = 380 nm), average size diameter about 5 nm and non-toxic; Cat-CNDs were incredibly potential for staining targeted tumor cells. The staining ability by confocal microscopy observations showed their green fluorescence images which meant that the CNDs easily penetrated HeLa cells via endocytosis. The resulting CNDs which were analyzed using some significant techniques approved that the prepared Cat-CNDs were tremendously dispersible and water-soluble, good colloidal stability, excellent biocompatibility, favorable hydrophilicity, high photostability, and non-toxicity.
The Use of Chemometrics for Classification of Sidaguri (Sida rhombifolia) Based on FTIR Spectra and Antiradical Activities Abdul Rohman; Asefin Nurul Ikhtiarini; Widiastuti Setyaningsih; Mohamad Rafi; Nanik Siti Aminah; Muhamad Insanu; Irnawati Irnawati; Djoko Santosa
Indonesian Journal of Chemistry Vol 21, No 6 (2021)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.64360

Abstract

Sidaguri (Sida rhombifolia) is one of the herbal components used in traditional medicine. The application of chemometrics in the standardization of herbal medicine is common. The objective of this study was to classify Sidaguri from different regions based on FTIR spectra with chemometrics of principal component analysis (PCA) and to correlate the antioxidant activities with FTIR spectra using the multivariate calibration of partial least square regression (PLSR). The extraction of Sidaguri powder was performed using ultrasound-assisted extraction (UAE) at optimum conditions. The obtained extracts were subjected to antiradical scavenging activities using DPPH (2,2’-diphenyl-1-picrylhydrazyl) and ABTS (2,2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid) radicals. The PCA result shows that Sidaguri from different regions could be separated using 14 wavenumbers of FTIR spectra based on the PCA's loading plot. PLSR regression using the second derivative FTIR spectra at wavenumbers of 3662–659 cm–1 could predict radical scavenging activities (RSA) of Sidaguri with R2 values of 0.9636 and 0.9024 for calibration and validation models, with RMSEC and RMSEP values of 1.45% and 2.65%, respectively. It can be concluded that FTIR spectra treated by PCA were reliable for classifying Sidaguri from different regions. At the same time, PLSR was accurate and precise enough to predict the RSA of Sidaguri.
PENDAMPINGAN MERDEKA BELAJAR BIDANG KIMIA KEPADA GURU DAN SISWA SMA DI KOTAWARINGIN BARAT – KALIMANTAN TENGAH Nanik Siti Aminah; Alfinda Novi Kristanti; Rico Ramadhan; Andika Pramudya Wardana; Tio Christiawan Bramayudha
Jurnal Layanan Masyarakat Vol. 6 No. 2 (2022): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jlm.v6i2.2022.492-499

Abstract

Kabupaten Kotawaringin Barat, Provinsi Kalimantan Tengah memiliki penduduk yang didominasi oleh usia muda/dewasa dan pemerintah daerah selalu berupaya meningkatkan kualitas SDM sebagai salah satu kiat menuju penguatan ekonomi yang merupakan fokus perhatian pemerintah. Departemen Kimia Universitas Airlangga mendukung usaha pemerintah daerah dengan menyelenggarakan kegiatan pengabdian masyarakat kepada guru SMA bidang Kimia dan siswa SMA. Kegiatan dilaksanakan pada 22 – 23 Agustus 2022 dan meliputi 3 program utama. Pertama, kegiatan pelatihan skrining bioaktivitas ekstrak tanaman dan penggunaan aplikasi Chemdraw sebagai platform pembelajaran siswa diperuntukkan kepada guru SMA sederajat. Kedua, kegiatan sosialisasi pendidikan sarjana dan demonstrasi praktikum kimia ditargetkan kepada siswa SMA sederajat. Kedua kegiatan ini diselenggarakan di SMAN 1 Pangkalan Bun, Kabupaten Kotawaringin Barat. Ketiga, international community service yang dihadiri melalui zoom meeting oleh mahasiswa internasional dan terintegrasi dengan program pengmas untuk siswa SMA. Rangkaian kegiatan ini diharapkan dapat membuka wawasan guru dan siswa SMA dalam mengimplementasikan merdeka belajar. Merdeka belajar merupakan pendekatan yang dilakukan agar siswa dapat mengoptimalkan bakat dan minat guna memberikan sumbangsih terbaik bagi bangsa.
Co-Authors Abdjan, Muhammad Ikhlas Abdul Rohman Abdul Rohman Abdul Rohman Abdul Rohman Abdullah Abdulloh Abdulloh Abdulloh Alfa Akustia Widati Alfi Hudatul Karomah Alfian, Fariz Rizky Alfinda Novi Kristanti Alsya Firdausi Nuzula Alsya Firdausi Nuzula Ana Firdausyah Andika Pramudya Wardana Andika Pramudya Wardana Asefin Nurul Ikhtiarini Asma Asma Auliya Ilmiawati Azalea Rahma Septianti Baharin, Siti Nor Atika Budi Prasetyo, Antonius Choirotul Isma Citra Putri Pramitha Didik Prasetyoko Didik Prasetyoko Didik Prasetyoko Djoko Santosa Emilia L. Ghisalberti Euis Holisotan Hakim Euis Holisotasn Hakim Ganden Suprianto Giman Giman Haq, Kautsar Ul Hariyanto, Geraldo Figo Hery Suwito Imam Siswanto Irnawati Irnawati Irnawati Irnawati Khoso, Mir Hasan Khusnul Wardah Mukharomah Lia Dewi Juliawaty Mahmiah Maria Bintang Marisa Nur Sahadatin Marisa Nur Shahadatin Masatake Niwa Mochamad Zakki Fahmi Mohamad Rafi Mohamad Rafi Mohamad Rafi Mohamad Rafi Mudasir Mudasir Mudasir Mudasir Muhamad Insanu Mulyadi Tanjung Nita Citrasari NUrina Fitriani, NUrina Qonitah Labibah Rico Ramadhan, Rico Rimuljo Hendradi Rusdipoetra, R. Aryabraga Satya Candra Wibawa Sakti Sefni Reza Yolanda Septaningsih, Dewi Anggraini Setyaningsih, Widiastuti Siti Maryam Siti Maryam Sjamsul Arifin Achmad Sjamsul Arifin Achmad Suhaili, Suhaili Susilowati, Rina Priastini Syarifah Asyura, Syarifah Takaya, Yoshiaki Taufik Taufik Tio Christiawan Bramayudha Tokok Adiarto Triyono Triyono Triyono Triyono Utami Dyah Syafitri Wardana, Andika Pramudya Wega Trisunaryanti Wega Trisunaryanti Win Darmanto Yana Maolana Syah Yaung Kwee Yoshiaki Takaya Yoshiaki Takaya