Garuda - Garba Rujukan Digital

PENGGUNAAN MEDIA SOSIAL (YOUTUBE) SEBAGAI MEDIA INOVATIF DALAM PEMBELAJARAN DI MADRASAH GRESIK Abdulloh, Abdulloh; Fahmi, Mochamad Zakki; Siswanto, Imam
Jurnal ABDI: Media Pengabdian Kepada Masyarakat Vol 5, No 1 (2019)
Publisher : Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/ja.v5n1.p33-37

The community service activities have been carried out at Madrasah Aliyah Masyhudiyah Gresik. Thepurpose of service is: 1) providing understanding to teachers in making learning material throughYouTube, 2) providing motivation to teachers, 3) building teachers' confidence, and 4) using YouTube forfun learning tools. Methods of activities are lectures, demonstrations, workshops and training using theCamtasia application. Data collection techniques are based on the results of the pretest - posttest andparticipatory approach. Data analysis to measure the success category is done by calculating thepercentage of correct answers for each aspect asked, the percentage of learning videos made and thenumber of learning videos uploaded. The results of the activities are: 1) the teacher's understanding inmaking construction of video-based learning materials on average increased by 52%, 2) 100% of teachershave made videos for learning media using the Camtasia application, 3) 30% of teachers have uploadedlearning videos on social media YouTube This activity resulted in an increase in teacher understandingrelated to the importance of using YouTube as a learning medium and videos containing learning materialscreated by madrasa teachers.

A BIPOTENTIOMETRIC FIA SYSTEM FOR DETERMINATION OF VITAMIN C ., Harjana; Siswanto, Imam; ., Muzakki; ., Sumardi; Huda, Miftahul
Indonesian Journal of Pharmacy Vol 14 No 1, 2003
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

A bipotentiometric FIA system has been developed for the determination of vitamin C. The systemÂ was a single stream manifold, which consisted of a peristaltic pump, a self made injector with internal loop and two Pt-electrodes connected to a PC by serial ADC or parallel ADC interface card. One of the Ptelectrodes was located in the injector before the internal loop, while the other electrodes at the end of the TEFLON reaction tube. The PC was supported with a self-made software for controlling the pump, signal acquisition, processing, and visualisation, and further peak determination, followed by calibration of standard solutions and calculation of sample concentrations. The above FIA-system configuration was applied to determine vitamin C by the injection of sample solution into a stream of potassium hexacyanoferrate (III) solution. The optimum result was achieved with knitted tube reaction of 0.8 mm i.d., 50 cm length, at flow rate 0,64 ml/minute, and consumed 3.6 ml of carrier solution per five injection, and gave linearity range at 0.001 â€“ 0.100 N vitamin C, with the coefficient of correlation 0.9999, RSD peak to peak better than 3.0% and the error of artificial samples were less than 3.4 %.Key Words : Bipotentiometric-FIA, injector with internal loop, module-program, vitamin C

Docking of New Designed Compounds Derived from 1,6-Dihydro-1,3,5-triazine-2,4-diamine Toward Quadruple Mutant Plasmodium Dihydrofolate Reductase Imam Siswanto; Harno Dwi Pranowo; Mudasir Mudasir
Indonesian Journal of Chemistry Vol 19, No 3 (2019)
Publisher : Universitas Gadjah Mada

Resistance to the traditional antifolates is now widespread in Plasmodium falciparum and Plasmodium vivax. To find the interaction model of some compounds derived from 1,6-dihydro-1,3,5-triazine-2,4-diamine, molecular docking technique was carried out using these compounds ligand and pDHFR as the receptor. Complex ligand and the receptor from Protein Data Bank (PDB ID 1J3K) were chosen as an interaction model between a ligand and its receptor. Each compound was optimized using ab initio methods with 6-311G basis set. Partial charges of ligand were added using AM1-BCC methods. Each ligand was docked to the receptor utilizing Dock6 software. Theoretical prediction based on the binding energy between these compounds as the ligand with pDHFR as receptor resulted in 1 compound, namely 6,6-dimethyl-1-[3-(2-chloro-4,5-dibromophenoxy)propoxy]-1,6-dihydro-1,3,5-triazine-2,4-diamine possessing binding affinity better than that of WR99210 which was known to have good antimalarial activity.

PENGGUNAAN MEDIA SOSIAL (YOUTUBE) SEBAGAI MEDIA INOVATIF DALAM PEMBELAJARAN DI MADRASAH GRESIK Abdulloh Abdulloh; Mochamad Zakki Fahmi; Imam Siswanto
Jurnal ABDI: Media Pengabdian Kepada Masyarakat Vol. 5 No. 1 (2019)
Publisher : Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/ja.v5n1.p33-37

The community service activities have been carried out at Madrasah Aliyah Masyhudiyah Gresik. Thepurpose of service is: 1) providing understanding to teachers in making learning material throughYouTube, 2) providing motivation to teachers, 3) building teachers' confidence, and 4) using YouTube forfun learning tools. Methods of activities are lectures, demonstrations, workshops and training using theCamtasia application. Data collection techniques are based on the results of the pretest - posttest andparticipatory approach. Data analysis to measure the success category is done by calculating thepercentage of correct answers for each aspect asked, the percentage of learning videos made and thenumber of learning videos uploaded. The results of the activities are: 1) the teacher's understanding inmaking construction of video-based learning materials on average increased by 52%, 2) 100% of teachershave made videos for learning media using the Camtasia application, 3) 30% of teachers have uploadedlearning videos on social media YouTube This activity resulted in an increase in teacher understandingrelated to the importance of using YouTube as a learning medium and videos containing learning materialscreated by madrasa teachers.

Pemanfaatan Teknologi Digital sebagai Media Pembelajaran untuk Guru SMA-SMP Muhammadiyah Gresik Alfa Akustia Widati; Fatiha Khairunnisa; Satya Candra Wibawa Sakti; Ganden Supriyanto; Mochamad Zakki Fahmi; Imam Siswanto; Hartati Hartati; Ali Rohman
Bubungan Tinggi: Jurnal Pengabdian Masyarakat Vol 5, No 2 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/btjpm.v5i2.6873

Guru mempunyai kewajiban besar memastikan anak didik memahami materi pelajaran. Namun, waktu belajar di kelas yang terbatas dan beragamnya kemampuan siswa menyebabkan metode pembelajaran tatap muka di kelas menjadi kurang efektif dalam meningkatkan pemahaman siswa. Tantangan dunia pendidikan menuntut guru harus memiliki kompetensi penguasaan teknologi digital. Video pembelajaran yang disajikan secara virtual adalah salah satu metode pembelajaran efektif untuk siswa. Oleh karena itu, guru seyogyanya memiliki kemampuan membuat video digital secara mandiri. Pengenalan jenis teknologi digital, instalasi dan penggunaan aplikasi pembuatan video telah dilakukan ke 45 orang Guru SMP-SMA Muhammadiyah Gresik pada tanggal 21 Juni 2022 untuk meningkatkan kompetensi guru terhadap pemanfaatan teknologi digital dalam pembelajaran. Metode pelaksanaan kegiatan meliputi pemberian materi oleh tenaga ahli, praktik peserta didampingi oleh mentor, dan pembuatan video secara mandiri. Berdasar hasil analisis nilai pre-test dan post-test saat kegiatan, terdapat peningkatan nilai peserta dari sebelum pelatihan (pre-test) adalah 76,8 dan setelah mengikuti pelatihan (post-test), nilai peserta menjadi 97,2. Peserta mendapatkan peningkatan pemahaman dalam membuat video pembelajaran yang ditunjukkan dengan hasil karya video pembelajaran yang dibuat secara individu oleh peserta. Video pembelajaran yang dihasilkan peserta juga telah memenuhi kriteria video digital yang baik. Data evaluasi kegiatan menunjukkan workshop ini diperlukan dan tepat sasaran untuk pengembangan profesional khususnya Guru SMP-SMA Muhammadiyah Gresik. Konsep kegiatan juga sesuai untuk menyelesaikan permasalahan yang ada di pendidikan tingkat SMP-SMA. Dengan demikian, pelatihan ini berhasil meningkatkan kompetensi peserta tentang penggunaan video dan teknologi digital sebagai salah satu inovasi pembelajaran.Teachers are responsible for ensuring students catch on to the subject matter. However, the limited study time in class and students' varying abilities cause face-to-face learning methods to be less effective in increasing student understanding. The global challenge of education demands teachers become competent in digital mastering technology. Learning videos that are presented virtually are an effective learning method for students. Consequently, teachers should have the ability to make digital videos independently. This study introduced digital technology types, installation, and video-making applications for teachers in Muhammadiyah's junior and senior high schools in Gresik (SMP-SMA Muhammadiyah Gresik) on June 21, 2022, increasing teacher competency in using digital technology in learning. The implementation method includes providing material by experts, having participants practice accompanied by mentors, and making videos independently. Based on the analysis of the pre-test and post-test scores during the activity, there was an increase in the participant's score from before the training (pre-test), which was 76.8. After participating in the training (post-test), the participant scored 97.2. Participants gain an increased understanding of making learning videos, as shown by the results of learning videos made individually by participants. The learning videos produced by the participants also met the criteria for good digital videos. Activity evaluation data show that this workshop is necessary and right on target for professional development, especially for SMP-SMA Muhammadiyah Gresik Teachers. The activity concept is also suitable for solving problems in junior high school level education. Thus, this training succeeded in increasing the competence of participants regarding the use of video and digital technology as one of the learning innovations.

The comparative of free energy binding between Pyrimethamine-pDHFR double mutant and Pyrimethamine-pDHFR quadruple mutant: Structure-based approach Abdjan, Muhammad Ikhlas; Aminah, Nanik Siti; Kristanti, Alfinda Novi; Takaya, Yoshiaki; Siswanto, Imam
Journal of Bio-Molecule Research and Engineering Vol 1 No 2 (2022)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbiome.v1i2.43982

Structure-based was performed to understand the mechanism inhibition of pyrimethamine (CP6) against Plasmodium Falciparum mutants at the molecular level. A molecular docking process was carried out to obtain the initial conformation of each system. The data showed in the form of RMSD values, hydrogen bonds, and grid scores. The results show that the RMSD value in the redocking process meets the criteria of the CP6-1J3J and WRA-1J3K complexes with a value of â‰¤ 2 í…. Several hydrogen bonds bind to receptor-active sites, including Ile14, Asp50, Ile164, and Asn108. Additionally, the grid score (kcal/mol) binds well on the active site: CP6-1J3J (-46.86), WRA-1J3K (-65.40), and CP6-1J3k (-44.71). Furthermore, molecular dynamics simulation was carried out to determine the free energy (âˆ†Gbind) of each complex using the MM/GBSA approach. The results show âˆ†Gbind (kcal/mol) in each complex, namely CP6-1J3J (-28.24), WRA-1J3K (-36.62), and CP6-1J3k (-24.23). Information on this research was expected to provide molecular insight into pyrimethamine as an antimalaria inhibitor.

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