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All Journal JURNAL GIZI INDONESIA World Nutrition Journal INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal)
Nurwanti, Esti
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Health Professions Medicine & Pharmacology Public Health

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How high-protein, high-fiber meal replacements influence dietary intake in overweight women during weight loss Muhammad, Harry Freitag Luglio; Nurwanti, Esti; Nurdin, Naufal Muharam
World Nutrition Journal Vol. 9 No. S1 (2025): Vol. 9 No. S1 (2025): Selected conference proceedings of the Nutri Symposium 2
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V09.S1.0023

Abstract

Background and objectives: This study aims to evaluate the effects of high-protein, high-fiber dietary supplements on dietary intake among overweight women.
Efektivitas Tepung Porang (Amorphophallus oncophyllus) Dalam Menurunkan Kadar Glukosa Darah dan Meningkatkan Berat Badan Pada Tikus Diabetes yang Diinduksi Streptozotocin Estiningsih, Daru; Nurwanti, Esti; Kusumawardani, Nurul; Suprapti, Sri
INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Vol. 9 No. 2 (2025)
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/inpharnmed.v9i2.6568

Abstract

Prevalensi diabetes mellitus tipe 2 meningkat secara signifikan, sehingga diperlukan intervensi berbasis pangan fungsional. Porang (Amorphophallus oncophyllus) mengandung glukomanan yang berpotensi sebagai terapi adjuvan diabetes. Mengetahui efek pemberian tepung porang terhadap kadar glukosa darah dan berat badan tikus diabetes yang diinduksi streptozotocin (STZ). Penelitian eksperimental dengan desain *pretest-posttest randomized controlled group design* menggunakan 30 ekor tikus jantan galur Wistar. Tikus dibagi menjadi 5 kelompok: normal, kontrol negatif, kontrol positif (glibenklamid 0,1 mg/kgBB), porang dosis 40 mg/kgBB, dan porang dosis 400 mg/kgBB. Diabetes diinduksi dengan STZ 45 mg/kgBB intraperitoneal. Pengukuran glukosa darah dilakukan hari ke-0, 7, dan 14, sedangkan berat badan diukur hari ke-0, 3, 7, 10, dan 14. Data dianalisis menggunakan ANOVA satu arah dilanjutkan uji LSD (p<0,05). Kelompok porang dosis 400 mg/kgBB menunjukkan penurunan glukosa darah yang signifikan dari 386,00±24,99 mg/dL menjadi 101,00±21,60 mg/dL (p<0,05), serta peningkatan berat badan dari 130,00±3,24 g menjadi 147,25±12,12 g. Hasil ini setara dengan kelompok glibenklamid dan lebih baik dibandingkan kelompok porang dosis 40 mg/kgBB. Tepung porang dosis 400 mg/kgBB efektif menurunkan glukosa darah dan meningkatkan berat badan pada tikus diabetes yang diinduksi STZ.
Effects of high-protein high-fiber meal replacements on weight loss and dietary composition in overweight women: A randomized controlled trial Nurwanti, Esti; Muhammad, Harry Freitag Luglio; Nguyen, Ngan Thi Kim; Nurdin, Naufal Muharam
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 14, No 1 (2025): December
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.14.1.102-110

Abstract

ABSTRACTBackground: Energy deficit is essential for weight loss; however, an effective weight loss program should also focus on improving dietary composition.Objective: This study aims to evaluate the effects of high-protein, high-fiber dietary supplements on weight loss and body composition improvements in overweight individuals.Methods: This experimental study utilized a randomized controlled trial (RCT) design. Participants were women and were randomly assigned to either a control group or an intervention group. Criteria of this study are: Female aged 20-30 years; Body Mass Index (BMI) between 25 and 30 kg/m²; No allergies, including soy allergies; Fasting blood glucose level (FBG) < 100 mg/dL. The control group received 2 sessions of nutritional counselling by nutritionists to follow a low-calorie diet, while the intervention group received the same counselling along with a daily meal replacement containing 184 kcal energy, 17 grams of protein and 5 grams of dietary fiber.Results: After an 8-week weight loss program, participants in the intervention group experienced significantly greater weight loss (-3.4 ± 0.43 kg) compared to the control group (-2.4 ± 0.5 kg) (p = 0.047). Additionally, a higher proportion of participants in the intervention group (62%) achieved the 5% weight loss threshold compared to the control group (28%) (Chi-Square p = 0.033). The intervention group also showed improvements in macronutrient composition compared to control, with a greater reduction in fat intake (-7.1 vs 2.1, p = 0.013) and increased consumption of protein (5.9 vs 1.8, p = 0.002) and fiber (7.21 vs 4.26, p = 0.026).Conclusion: The use of high-protein, high-fiber meal replacements was associated with improvement of weight loss compared to standard low-calorie diet counselling alone.Keywords: Diet; meal replacement; obesity; weight loss
Co-Authors Estiningsih, Daru Harry Freitag Luglio Muhammad Kusumawardani, Nurul Naufal Muharam Nurdin Nguyen, Ngan Thi Kim Sri Suprapti